WEAR
·
2021
·
IF 3.892
F.S. Meng,Z. Li,H.H. Ding,J.S. Hu,W.J. Wang,J. Guo,Q.Y. Liu
The advanced nano-additives can improve the lubrication performance of nanolubricants efficiently, which could greatly reduce energy consumption. Here, we prepared the BN coated with carbon layer (BN@C) by a novel hydrothermal coating method with pristine BN nanosheets as matrix material and glucose as carbon source. And the BN@C exhibited excellent lubrication performance as a lubricant additive . In order to investigate the tribological properties, BN@C was modified with oleic acid as a surfactant , and the friction tests were carried out on an MRS-10A four-ball friction and wear tester. Benefitting from the stable dispersity, ultrasmall particle size and the surface carbon layer of BN@C-OA, the lubrication performance was significantly improved. More impressively, BN@C-OA could enter the interface of friction pairs . The interlayer sliding occurred to improve the anti-wear and anti-friction properties. This study could provide a new avenue to synthesize the coating-containing nanocomposite additive to promote the lubrication properties of nanoparticles in oil.
研究领域:
材料科学
·
机械工程
✓ 已验证
产品关联
DOI
高影响因子
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
·
2016
·
IF 2.76
Ting Yang,Xuejun Cui,Yanbing Kao,Hongyan Wang,Jihong Wen
Hydroxyapatite (HA) nanoparticles were modified by oleic acid (OA) to improve their lipophilicity and the dispersibility in polymer. XRD and FTIR demonstrated that the surface modification did not change the chemical properties of HA. OA modified HA (OA-HA) nanoparticles were introduced into polytrimethylene carbonate/gelatin (PTMC/Gt) composite fiber scaffolds (CFSs) by electrospinning. Scanning electron microscope (SEM) showed that the distribution of OA-HA nanoparticles was more uniform than that of HA nanoparticles in the CFSs. Comparing PTMC/Gt CFSs, PTMC/Gt/HA CFSs and PTMC/Gt/OA-HA CFSs, PTMC/Gt/OA-HA CFSs showed the best mechanical property and more hydrophilic. Cell adhesion and proliferation assay (MTT assay) and confocal laser scanning microscopy (CLSM) demonstrated that the PTMC/Gt/OA-HA CFSs could provide a higher cell adhesion and proliferation environment for mandibular condylar chondrocytes(MCCs). Overall the PTMC/Gt/OA-HA CFSs have nontoxicity and good biocompatibility with MCCs and would be potential to be used in the field of bone and cartilage tissue engineering scaffolds in the future.
研究领域:
生物材料学
·
组织工程学
·
医学
✓ 已验证
产品关联
DOI
高影响因子
COLLOIDS AND SURFACES B-BIOINTERFACES
·
2019
·
IF 3.973
Yuxiang Sun,Fangfang Shi,Yajun Niu,Yu Zhang,Fei Xiong
Lipid deposition induced various diseases including nonalcoholic fatty liver and hyperlipemia. The excessive accumulation of triglyceride (TG) and the deposition of fat were the two most critical causes. Here, we developed Fe 3 O 4 @ [email protected] nanoparticles (NPs) with amphiphilic structures, which exhibited an excellent role in eliminating excess TG. Hydrophobic TG was adsorbed efficiently by Fe 3 O 4 @ [email protected] NPs through the “liposuction effect” and the formation of [email protected] complex was then conducted. The [email protected] complex was further enclosed by the endosome based on the endocytosis and subsequently was taken into the lysosome, degrading with the help of lipases. Meanwhile, the “nano-enzyme effect” of Fe 3 O 4 NPs recovered the lipid-regulated proteins including PPARα, further triggering biodegradation pathways of TG, although the lipid-regulated proteins were obviously inhibited in the high-fat hepatocytes models. These two mechanisms of Fe 3 O 4 @ [email protected] NPs together achieved the down-regulation of TG in vivo and in vitro. Therefore, our findings provided a novel thought in treating these diseases associated with lipid deposition, that is, nanoparticles modified by specific structure exhibit a superior TG removal.
研究领域:
纳米技术
·
药理学
·
肝病学
·
生物医学工程
✓ 已验证
产品关联
DOI
PubMed
高影响因子
ADVANCED FUNCTIONAL MATERIALS
·
2011
·Vol. 21
·期 23
·4470-4477
·
IF 8.508
Meng He,Peng Huang,Chunlei Zhang,Hengyao Hu,Chenchen Bao,Guo Gao,Rong He,Daxiang Cui
A novel OA/ionic liquid two-phase system combining the merits of thermal decomposition method, the IL-based strategy, and the two-phase approach is introduced to synthesize high-quality lanthanide-doped NaGdF 4 upconversion nanocrystals with different crystal-phases in OA-phase and IL-phase through a one-step controllable reaction. Oil-dispersible cubic-phase NaGdF 4 :Yb, Er (Ho, Tm) nanocrystals with ultra-small size (∼5 nm) and monodispersity are obtained in the OA phase of the two-phase system via an IL-based reaction. More importantly, water-soluble hexagonal-phase NaGdF 4 :Yb, Er nanocrystals are obtained in the same system simply by adopting an extremely facile method to complete the dual phase-transition (crystal-phase transition and OA-phase to IL-phase transition) simultaneously. The synthesized lanthanide-doped NaGdF 4 upconversion nanocrystals are effective for dual-mode UCL imaging and CT imaging in vivo.
研究领域:
材料科学
·
生物医学工程
·
纳米医学
✓ 已验证
DOI
高影响因子
MOLECULES
·
2024
·Vol. 29
·期 16
·3747
·
IF 4.2
Guanyu Chen,Weixin Zhang,Rongshu Zhu,Yanpeng Chen,Minghu Zhao,Mei Hong
Zeolite-based catalysts efficiently catalyze the selective catalytic reduction of NOxwith methane (CH4-SCR) for the environmentally friendly removal of nitrogen oxides, but suffer severe deactivation in high-temperature SO2- and H2O-containing flue gas. In this work, SSZ-39 zeolite (AEI topology) with high hydrothermal stability is reported for preparing CH4-SCR catalysts. Mild acid leaching with oxalic acid (OA) not only modulates the Si/Al ratio of commercial SSZ-39 to a suitable value, but also removes some extra-framework Al atoms, introducing a small number of mesopores into the zeolite that alleviate diffusion limitation. Additional Co3O4modification during indium exchange further enhances the catalytic activity of the resulting In-Co3O4/H-SSZ-39(OA). The optimized sample exhibits remarkable performance in CH4-SCR under a gas hourly space velocity (GHSV) of 24,000 h−1and in the presence of 5 vol% H2O. Even under harsh SO2- and H2O-containing high-temperature conditions, it shows satisfactory stability. Catalysts containing Co3O4components demonstrate much higher CH4conversion. The strong mutual interaction between Co3O4and Brønsted acid sites, confirmed by the temperature-programmed desorption of NO (NO-TPD), enables more stable NxOyspecies to be retained in In-Co3O4/H-SSZ-39(OA) to supply further reactions at high temperatures.
研究领域:
环境科学
·
催化化学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Advanced Science
·
2026
·
IF 14.1
Meng Zheng,Changyu Liu,Qin Xia,Arndt F Schilling,Jiawei Jiang,Renpeng Peng,Zixing Shu,Tian Ma,Danni Luo,Yaoyu Zhang,Yibo Fan,Xuyuan Zhang,Song Li,Kai Wang,Wentao Ke,Yuan Xiong,Yuanli Zhu,Fangzhi Mou,Jun Xiao,Hao Zhu
Osteoarthritis (OA) is a prevalent degenerative joint disease with limited effective treatment options. Joint inflammatory pain is a primary reason patients seek care, but systemic drug administration often causes severe side effects, while intra‐articular injection suffers from rapid clearance and poor tissue penetration. Herein, we develop nanozyme‐based Janus nanomotors loaded with metformin (MET) for reactive oxygen species (ROS)‐targeted therapy in OA. Leveraging intrinsic superoxide dismutase (SOD) and catalase (CAT) enzymatic activity, these nanomotors harness pathologically elevated ROS within the articular microenvironment as chemical fuel, achieving self‐propelled deep penetration into both cartilage and synovial tissue. This mechanism facilitates simultaneous on‐the‐move ROS scavenging and sustained deep‐tissue MET release, which further restores redox homeostasis and protects chondrocytes by regulating the NRF2/KEAP1 signaling pathway. Furthermore, the nanomotors can suppress nociceptive signaling in the dorsal root ganglia (DRG), thereby alleviating joint pain and improving mobility. This research offers a novel and efficient approach for cartilage protection and arthritis pain management. ROS‐responsive NM@MET nanomotors utilize elevated ROS in osteoarthritic joints to promote deep penetration into cartilage and synovium and enable sustained metformin release. By scavenging ROS, regulating NRF2/KEAP1 signaling, protecting chondrocytes, suppressing synovial inflammation, and attenuating nociceptive signaling, NM@MET alleviates pain and improves joint function.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Materials Today Bio
·
2024
·
IF 8.7
Yun Zhou,Xu He,Wen Zhang,Weiguo Zhang,Huan Zhao,Xichao Zhou,Qiaoli Gu,Hao Shen,Huilin Yang,Xingzhi Liu,Lixin Huang,Qin Shi
Osteoarthritis (OA) is a degenerative disease potentially exacerbated due to inflammation, cartilage degeneration, and increased friction. Both mesenchymal stem cells (MSCs) and pro-inflammatory macrophages play important roles in OA. A promising approach to treating OA is to modify multi-functional hydrogel microspheres to target the OA microenvironment and structure. Arginyl-glycyl-aspartic acid (RGD) is a peptide widely used in bioengineering owing to its cell adhesion properties, which can recruit BMSCs and macrophages. We developed TLC-R, a microsphere loaded with TGF-β1-containing liposomes. The recruitment effect of TLC-R on macrophages and BMSCs was verified by in vitro experiments, along with its function of promoting chondrogenic differentiation of BMSCs. And we evaluated the effect of TLC-R in balancing OA metabolism in vitro and in vivo . When TLC-R was co-cultured with BMSCs and lipopolysaccharide (LPS)-treated macrophages, it showed the ability to recruit both cells in substantial numbers. As the microspheres degraded, TGF-β1 and chondroitin sulfate (ChS) were released to promote chondrogenic differentiation of the recruited BMSCs, modulate chondrocyte metabolism and inhibit inflammation induced by the macrophages. Furthermore, in vivo analysis showed that TLC-R restored the narrowed space, reduced osteophyte volume, and improved cartilage metabolic homeostasis in OA rats. Altogether, TLC-R provides a comprehensive and novel solution for OA treatment by dual-modulating inflammatory and chondrocyte metabolism.
研究领域:
生物医学工程
·
骨科
·
再生医学
·
炎症生物学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF LUMINESCENCE
·
2019
·
IF 2.961
Yan Hua,Daocheng Hong,Sushu Wan,Yanyu Lei,Mingcai Xie,Weiqing Yang,Yu Du,Yuxi Tian
2D perovskite materials have attracted increasing attention in the last few years due to their optical tunability. However, how to control the structure of these materials is still one of the key challenges. In this work, by using photoluminescence microscopy and XRD characterization, we found that ethanol treatment can induce the reorganization of the crystal structure of 2D perovskite materials. The ethanol molecules can insert into (OA) 2 (MA)Pb 2 I 7 (OA = CH 3 (CH 2 ) 7 NH 3 ; MA = CH 3 NH 3 ) crystal lattice and preferentially dissolve MA ions reducing the MA/OA ratio. During the recrystallization, new (OA) 2 PbI 4 phase forms due to the low MA/OA ratio. On the other hand, adsorption of ethanol can induce the photoluminescence (PL) enhancement by passivation of the surface defects . Consequently, PL intensity increases and decreases as the activation/deactivation of the quenching defects. These results provide a possible way to optimize the crystal structure of 2D perovskite under mild condition.
研究领域:
材料科学
·
光学
✓ 已验证
产品关联
DOI
高影响因子
Advanced Optical Materials
·
2023
·Vol. 11
·期 13
·2300064
·
IF 9
Guoqing Xu,Shuoshuo Zang,Hewen Liu
The evidence on deciphering nucleation and growth of cesium lead halide perovskite crystals, and establishing the phase diagram of cesium lead halide perovskites of different dimensions is still lacking. In this work, a facile method for the synthesis of cesium lead bromide crystals of different molecular level dimensions at room temperature is presented by varying the OA/OAm ratios without changing the proportions of Cs and Pb precursors. Bromide ions are gradually released in the systems through the gamma-ray radiation chemistry of bromobenzene. As the volume ratios of OA/OAm increase, different products such as CsBr, Cs 4 PbBr 6 (0D), white δ -CsPbBr 3 (1D), γ -CsPbBr 3 (3D) associated with PbBr 2 sheets, and γ -CsPbBr 3 are obtained in order. 1D δ -CsPbBr 3 can be transformed into 2D CsPb 2 Br 5 through CsBr stripping in water. The phase diagram established in this work is helpful for understanding the nucleation and growth mechanism of Cs–Pb–Br perovskite crystals of different dimensions. The nucleation of Cs–Pb–Br perovskite crystals is driven by the supersaturation of either CsBr or PbBr 2 caused by varying OA/OAm ratios, i.e., 0D Cs 4 PbBr 6 at the supersaturation of CsBr, while 3D γ -CsPbBr 3 at the supersaturation of PbBr 2 . 1D perovskite is the intermediate state between 0D and 3D perovskites.
研究领域:
材料科学
·
化学
✓ 已验证
产品关联
DOI
高影响因子
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2024
·
IF 7.7
Wei Luo,Yang Yang,Yunxuan Weng,Zhigang Huang,Caili Zhang
Moisture exposure during polyester processing can lead to degradation, resulting in the formation of carboxyl and hydroxyl end-groups. To preserve mechanical properties, thorough drying and the use of chain extenders like epoxy acrylates and isocyanates during extrusion are crucial for maintaining or enhancing molecular weight through in-situ reactions. Our study introduced epoxidized cardanol oleate (ECD-OA), containing epoxy and long-chain alkyl groups, as a potential chain extender, and compared its effectiveness with commercially available epoxidized cardanol glycidyl ether (cardolite NC514). Compared to neat PLA without chain extension, the addition of 1 phr ECD-OA resulted in an increase in the molecular weight ( M w ) of PLA from 15.3 × 10 4 g/mol to 17.1 × 10 4 g/mol, demonstrating a chain extension efficiency of 11.8 %. The melt flow rate of PLA decreased from 9.9 g/10 min to 5.0 g/10 min, and the initial thermal degradation temperature of PLA increased by 5.7 °C. Upon chain extension, there was a substantial increase in both the elongation at break and tear resistance of the PLA film. The results demonstrate that ECD-OA can extend PLA molecular chains through chemical reactions and promote entanglement with the long alkane chain, consequently enhancing the mechanical and thermal properties of PLA. Due to the enzyme's preference for biobased small molecules, the PLA film with the addition of a biobased chain extender is more prone to enzymatic degradation compared to neat PLA. To conclude, ECD-OA acts as a bio-based chain extender that improves the performance of PLA while also enhancing its biodegradability.
研究领域:
聚合物科学
·
材料科学
·
生物降解材料
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Materials Horizons
·
2025
·
IF 10.7
Meiyan Liu,Xiuchen Wang,Yajing Wang,Bobo Shi,Jiaxin Feng,Zhe Liu
To break through the performance bottlenecks of electromagnetic protection materials in terms of lightweight design, broadband absorption, and multifunctional integration, this work proposes a synergistic design strategy based on magneto–dielectric coupled absorbing units and periodic micro-circular array superstructures. At the microscopic scale, oleic acid (OA)-modified γ-Fe2O3/graphene oxide (OA-γ-Fe2O3/GO) composite absorbing units were constructed and organized into precisely controllable millimeter-scale periodic micro-circular arrays. Acting as an artificial electromagnetic structure capable of actively modulating the electromagnetic field distribution, the array enables multiple scattering, progressive attenuation, and continuous impedance transition within the interface, thereby significantly optimizing the energy dissipation pathways. A pressing process was employed to integrate polytetrafluoroethylene (PTFE) onto the fabric surface, realizing a high-performance composite fabric with an overall thickness of only 0.128 mm. The resulting composite exhibits outstanding performance, with a shielding effectiveness (SET) of 73.99 dB, a minimum reflection loss (RLmin) of −31.56 dB, and an effective absorption bandwidth (RL < −10 dB) spanning 10.93–11.83 GHz. Meanwhile, it demonstrates excellent multifunctional properties, including a water contact angle of 125.7°, a tensile strength of 142 MPa, and the retention of 93% of its initial shielding performance after 10 000 bending cycles. Compared with commercial thin shielding textiles, the proposed material achieves an improvement of over 20% in shielding effectiveness and over 30% in absorption performance. This study not only provides a high-performance electromagnetic protection material but also establishes a cross-scale “unit–structure” synergistic design framework, offering a new fundamental paradigm for developing intelligent and adaptive electromagnetic protection systems. The strategy holds great potential for applications in stealth technology, aerospace engineering, and wearable electronics.
研究领域:
材料科学
·
电磁功能材料
·
纳米复合材料
·
柔性电子学
·
表面工程
✓ 已验证
产品关联
DOI
PubMed
高影响因子
SEPARATION AND PURIFICATION TECHNOLOGY
·
2024
·
IF 8.1
Jie-Ping Fan,Ping Gan,Feng-Hui Tao,Hui-Ping Chen,Hai-Long Peng,Yu-De Liu,Chun-Fang Xie
Oleanolic acid possesses a wide variety of pharmacological activities and spreads in various plants, but always co-exist with its isomers ursolic acid. Separating oleanolic acid with high efficacy from ursolic acid contaminated plant extracts is quite important. This study prepared a molecularly imprinted poly(OA[AMI] supramolecular hydrogel) (MIPSHG@OA) for selectively enriching oleanolic acid, by using the 1-allyl-3-methylimidazolium oleanolic salt (OA[AMI]) as hydrogelator, template, functional monomer and basement. The preparation conditions were optimized as 12.5 mg OA[AMI], 40 mg MBA, 4 ml solvent, 10 mg APS, and 30 μl TEMED. The characterization by FT-IR spectra, TG analysis, SEM image and equilibrium swelling ratio showed a sheet and porous structure and a large equilibrium swelling ratio of the obtained MIPSHG@OA. The adsorption performance showed the obtained MIPSHG@OA was homogeneous on the surface and uniform on the adsorption sites, the adsorption of oleanolic acid on the polymers was chemisorption and monolayer, the adsorbed oleanolic acid molecules did not interact with each other, the MIPSHG@OA had high competitive recognition performance and imprinting efficiency on oleanolic acid, and had good recyclability. In the solid phase extraction application, the results demonstrated that the synthesized MIPSHG@OA could selectively enrich oleanolic acid.
研究领域:
分析化学
·
药学
·
植物化学
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）