COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
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2024
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IF 4.9
Nian Liu,Sen Liang,Jingtao Li,Qi Li,Shuo Bai,Jing Hu
Poly (amino acid)s-based hydrogels with high biological safety and natural antibacterial capabilities have significant clinical value in wound repair dressings. Poly ( γ -glutamic acid) (PGA) and ε -poly-lysine (EPL) are among the few poly (amino acid)s that are widely available and can be biosynthesized on a large scale. In this study, PGA and EPL were selected as backbone molecules, and the complex of protocatechuic aldehyde and iron (PA@Fe) with photothermal effects was introduced to prepare the poly (amino acid)s-based antibacterial wound repair gel PGA-EPL-PA@Fe (PEPF). The PEPF gel dressing exhibited excellent adhesive, antibacterial, antioxidant, and other multiple properties, significantly promoting wound healing in rats, indicating the high clinical application prospects of poly (amino acid)s-based dressings.
研究领域:
生物医学工程
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材料科学
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伤口愈合
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药剂学
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DOI
高影响因子
SEPARATION AND PURIFICATION TECHNOLOGY
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2026
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IF 9.1
Xinxin Zhu,Liting Wang,Joe R. Zhao,Shoujuan Wang,Magdi E. Gibril,Fangong Kong
The rising contamination of water resources by levofloxacin (LEV) requires advanced remediation strategies that exceed the capabilities of the conventional methods. This study reports the rational design of a novel, multi-functional cellulose-phytic acid/Fe-MoS 2 (cellulose-PA/Fe-MoS 2 ) hybrid composite for the highly efficient removal of LEV via synergistic adsorption and photocatalysis. Cellulose served as sustainable substrate and phytic acid acted as a natural cross-linker to enhance the integration and distribution of Fe-MoS 2 onto cellulose substrate. This designed architecture results in enhanced hydrophilicity, minimized MoS 2 aggregation, and a maximized density of active sites, as confirmed by comprehensive characterization (SEM, XRD, FTIR, XPS, BET, LC-MS, EPR). The prepared composite demonstrated exceptional, temperature-dependent LEV adsorption capacities of up to 210.97 mg/g (95%) within 40 min, with kinetics and isotherms best described by pseudo-second-order and Langmuir models, indicative of chemisorption. The adsorption mechanism driven by a combination of electrostatic attraction, π–π stacking, hydrogen bonding, and coordination complexation, resulting in effective removal across a broad pH range (3−10). The cellulose-PA/Fe-MoS 2 exhibited photocatalytic effect, achieving efficient degradation of levofloxacin (LEV) (98.5%) within short time (15 mins) into small molecules (CO 2 , H 2 O, NH 3 , NO 3 , F, …etc.) as confirmed with LC-MS, driven primarily by reactive species (•O 2 − , •OH, h + ). In addition, it was demonstrated good recyclability, maintaining high performance over five consecutive cycles. These findings suggest that the designed cellulose-PA/Fe-MoS 2 composite could be used as a green and sustainable multifunctional material to simultaneously remove and degrade antibiotics from water environments.
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高影响因子
CHEMISTRY & BIODIVERSITY
·
2023
·Vol. 20
·期 8
·e202300831
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IF 2.9
Fengyun Chen,Ansar Javeed,Qiuyu Zeng,Quan Zhang,Bingnan Han
Bacterial infected environments and resulting bacterial infections have been threatening the human health globally. Due to increased bacterial resistance caused by improper and excessive use of antibiotics, antibacterial biomaterials are being developed as alternatives to antibiotics in some cases. Herein, an advanced multifunctional hydrogel with excellent antibacterial properties, enhanced mechanical properties, biocompatibility and self-healing performance, was designed through freezing-thawing method. This hydrogel network is composed of polyvinyl alcohol (PVA), carboxymethyl chitosan (CMCS), protocatechualdehyde (PA), ferric iron (Fe) and an antimicrobial cyclic peptide actinomycin X2 (Ac.X2). The double dynamic bonds among protocatechualdehyde (PA), ferric iron (Fe) and carboxymethyl chitosan containing coordinate bond (catechol-Fe) as well as dynamic Schiff base bonds and hydrogen bonds endowed the hydrogel with enhanced mechanical properties. Successful formation of hydrogel was confirmed through ATR-IR and XRD, and structural evaluation through SEM analysis, whereas mechanical properties were tested with electromechanical universal testing machine. The resulting PVA/CMCS/Ac.X2/PA@Fe (PCXPA) hydrogel has favorable biocompatibility and excellent broad-spectrum antimicrobial activity against both S. aureus (95.3 %) and E. coli (90.2 %) compared with free-soluble Ac.X2, which exhibited subpar performance against E. coli reported in our previous studies. This work provides a new insight on preparing multifunctional hydrogels containing antimicrobial peptides as antibacterial material. Graphical
研究领域:
生物材料学
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医学
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药剂学
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DOI
PubMed
高影响因子
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
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2025
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IF 8.5
Menghan Guo,Wenqing Wang,Jing Zhang,Pengfei Qi,Yifan Yan,Rui Wang
As a substitute for petroleum-based polymers, polylactic acid (PLA) always attracts great interest due to its unique eco-friendly properties and versatile applications. However, the inherent high flammability and slow natural degradation are still challenging for its wide usage. In this study, a multi-level sushi roll structured flame retardant (B@(D + E)@P-Fe) composed of boron nitride nanosheets (BNNS), iron metal-organic frameworks (Fe-MOFs), and phytic acid (PA) was synthesized through self-assembly technology and create a flame retardant PLA system. Loading of 6 wt % B@(D + E)@P-Fe enabled the PLA composites reached UL-94 V-0 rating and increased the LOI value up to 30 %. Cone calorimetry tests revealed that, compared with pure PLA, PLA composite exhibited a 32.6 % reduction in peak heat release rate and a 17.5 % reduction in total heat release. In addition, the composite material increased its crystallinity up to 51.2 % and maintained excellent mechanical properties with the modulus increasing from 2704.16 to 3448.52 MPa. Meanwhile, the as-synthesized flame retardant could be recycled with yield up to 81 %, and the purity of recovered lactic acid was 85.2 %, realizing a full life cycle of biodegradable PLA materials. This work presents a facile and eco-friendly strategy to fabricate renewable plastic with both good flame retardancy and high degradation efficiency.
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PubMed
高影响因子
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
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2022
·
IF 5.518
Xuemei Bao,Furong Wang,Qianqian Liu,Fengjiao Yu,Yang Yang
Despite enormous application prospect in wastewater treatment , the moderately hydrophilic ultrafiltration (UF) membrane with the intrinsic pore size has been proved ineffective for removal of highly emulsified oil droplets and organic dyes merely by the size screening effect. Although modification of polymer fibrous membranes by the phytic acid (PA)-metal complex coatings has been widely investigated for updating the membrane performances, the feasibility of this simple dip-coating approach in modifying polymer UF membrane with an asymmetric structure is still unrevealed and required testifying. Herein, we report the modification of asymmetric polysulfone (PSF) UF membranes through the formation of hydrophilic PA-Fe III complex coatings via controlled aggregation. We reveal that 1-cycle crosslinked PA-Fe III sequential assembly with adequate reaction time represents the optimal conditions for achieving PA-Fe III /PSF membranes with desired wettability , separation performances and reusability. The PA-Fe III complex aggregations afford the hierarchical roughness and the high density of phosphonic acid group, which favors the trapping of water and formation of a stable hydration layer to separate highly emulsified oil droplets and prevent them from fouling the membrane. Besides, the molecular layer deposition mode of the PA-Fe III compact film enables a fine adjustment of the pore aperture, guaranteeing the simultaneous rejections to small-sized emulsified droplets and non-specific organic dye molecules. The rapid, easy to scale up, and cost-effective modification process for polymer UF membranes is expected to be of technological significance for various practical applications, especially for sophisticated oily wastewater decontamination .
研究领域:
膜科学
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环境工程
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水处理
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材料科学
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高影响因子
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