TALANTA
·
2025
·
IF 6.1
Xi Wu,Chenggang Geng,Weiwei Cheng,Zhenjiong Wang,Yan Zhang,Di Wu,Xiaozhi Tang
In this reasearch, a homogeneous electrochemical sensor based on PCN-224@MB@Apt was fabricated for the ultrasensitive determination of ochratoxin A (OTA). Firstly, nanoscale PCN-224 were synthesized as the nanocarrier to embed the signal probe of methylene blue (MB). Then, the OTA aptamer (Apt) was added and connected to PCN-224@MB via the Zr– O –P bond between Zr metal sites of PCN-224 and phosphate group of Apt as the biogate. When OTA exists, the Apt would preferentially bind with OTA and fall off from PCN-224@MB, leading to the release of MB and generation of differential pulse voltammetry (DPV) response. The DPV response of MB was linearly correlated with the amount of OTA. The optimized PCN-224@MB@Apt sensor showed outstanding detection performance towards OTA with a low detection limit of 2.6 × 10 −5 ng/mL (S/N = 3) and wide linear range (10 −4 -10 ng/mL). Meanwhile, the fabricated homogeneous electrochemical sensor exhibited splendid stability, reproducibility, and specificity. To assess the practical applicability, the PCN-224@MB@Apt sensor was applied to detect OTA in real corn samples and desirable recovery rates varying from 83.2 % to 109.6 % were obtained.
研究领域:
分析化学
·
食品安全检测
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产品关联
DOI
PubMed
高影响因子
JOURNAL OF MATERIALS SCIENCE-MATERIALS IN ELECTRONICS
·
2024
·Vol. 35
·期 26
·1-11
·
IF 2.8
Li Xiao-Bing,Ma Xiao-Ye,Zhang Xue-Feng,Jia Guo-Liang,Zhao Zhao-Ye,Wang Jun-Chuan,Wang Hui,Wu Xiang-Feng
In this work, PCN-224(Fe) porphyrin-based metal–organic frameworks and a Poly(ionic liquids) (PILs) were used to prepare PCN-224(Fe)@PIL(Cl − ) composite films by UV polymerisation. The structure, morphology, chemical composition, and electrochemical properties of the as-prepared composite film were investigated. PCN-224(Fe) was coated with a kind of P(1-vinylpyridinium chloride as monomer) on the outside to improve the electron transfer efficiency, while an electrochemical system was employed to catalysis the persulfate (PS) decomposition for the efficient degradation of tetracycline (TC). Because of the cathodic reduction reaction, the continuous redox cycle between Fe 3+ /Fe 2+ was facilitated, which enhanced the degradation activity of persulfate on tetracycline. The PCN-224(Fe)@PIL(Cl − ) composite demonstrated a superior electrocatalytic degradation efficiency of 95.8% in just 40 min for the TC model pollutant, surpassing the 63.3% efficiency of pure PCN-224(Fe) within 60 min. This work shows a successful example of using PILs to enhance catalytic degradation activity and points out a direction of preparation of catalysts for activating persulfate (PS).
研究领域:
环境科学
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材料科学
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电化学
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产品关联
DOI
高影响因子
Foods
·
2021
·Vol. 10
·期 2
·419
·
IF 4.35
Pei Hu,Zhentao Sun,Yunwen Shen,Yiwen Pan
Hydrogen peroxide (H2O2) has been reported to be used for the illegal treatment of fishery products in order to obtain “fake” freshness. Residues of H2O2in food may be of toxicology concern. In this study, a nonenzymatic sensor was developed based on Fe@PCN-224 metal–organic frameworks wrapped by Nafion to detect H2O2concentration. The hybrid structure of Fe@PCN-224 was fabricated by incorporated free FeIIIions into the center of PCN-224, which was ultra-stable due to the strong interactions between Zr6and the carboxyl group. Scanning electron spectroscopy images exhibited that Nafion sheets crossed together on the surface of Fe@PCN-224 nanoparticles to form a hierarchical and coherent structure for efficient electron transfer. Electrochemical investigations showed that the Fe@PCN-224/Nafion/GCE possessed good linearity from 2 to 13,000 μM (including four orders of magnitude), low detection limits (0.7 μM), high stability in continuous monitoring (current remained nearly stable over 2300 s) and in long-term measurement (current decreased 3.4% for 30 days). The prepared nanohybrid modified electrode was effectively applied to H2O2detection in three different fishery products. The results were comparable to those measured using photometrical methods. The developed electrochemical method has a great potential in detecting the illegal management of fishery products with H2O2.Keywords:Fe@PCN-224;Nafion;nonenzymatic sensor;hydrogen peroxide;fishery products
研究领域:
食品安全检测
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电化学分析
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材料科学
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DOI
PubMed
高影响因子
KINETICS AND CATALYSIS
·
2025
·
IF 1.4
Jiang Xin,Zeng Zhenxing
Interfacing two semiconductors for heterojuctions construction has been considered as an effective way to facilitate electron-hole separation, thus improving the photocatalytic activity. In this paper, PCN-224/g-C 3 N 4 heterojunction was constructed by PCN-224 and g-C 3 N 4 using a solvothermal method. Transmission electron microscopy (TEM) images reveal a well-matched, smooth interface between PCN-224 and g-C 3 N 4 , demonstrating the successful formation of a tight junction. Photoelectric performance tests confirm that the heterojunction significantly enhances the light absorption capability within the visible range and improves the efficiency of electron-hole separation. Herein, the PCN-224/g-C 3 N 4 heterojunction exhibited excellent photocatalytic activity in both disinfection and organic pollutant degradation. Under visible light irradiation (λ > 420 nm) for 3 h, it completely degraded phenol and effectively inactivated E. coli . In the photocatalytic process, electrons migrate from the conduction band of g-C 3 N 4 to PCN-224, while holes transfer from the valence band of PCN-224 to the valence band of g-C 3 N 4 , thereby generating \({\text{O}}_{2}^{{\bullet - }}\) and h + radicals. These generated radicals effectively oxidize and degrade phenol.
研究领域:
材料科学
·
环境科学
·
化学工程
·
纳米技术
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DOI
高影响因子
Environmental Science-Nano
·
2018
·Vol. 6
·期 1
·207-215
·
IF 6.087
Miao Peng,Guijian Guan,Hong Deng,Bin Han,Chen Tian,Junyang Zhuang,Yunyun Xu,Weizhen Liu,Zhang Lin
Considering p-arsanilic acid (p-ASA) as an organoarsenic pollutant, monitoring concentration of p-ASA is significant to maintain environmental security. Photoelectrochemical (PEC) detection is promisingly applied in environmental monitoring for its lower cost and simpler operation, compared to traditional techniques. However, general electrode materials of PEC sensors need to be modified with biological probes due to lack of specific binding sites to analytes, which may lead to complicated sensor fabrication and bio-recognizers inactivation during storage. Herein, a porphyrinic metal–organic framework/reduced graphene oxide (PCN-224/rGO) nanocomposite with simultaneously excellent photoelectric activity and strong binding characteristics was prepared and used to fabricate a PEC sensor for p-ASA detection avoiding the modification of bio-recognizers. Benefiting from the high conductivity of rGO, the separation efficiency of charge carriers was improved in PCN-224/rGO and thereby photocurrent gained an amplification of about 12 times. The PCN-224/rGO nanocomposite had strong affinity to p-ASA via Zr–O–As coordination and π–π stacking. Significantly, the binding of p-ASA could adjust the band position of PCN-224/rGO and facilitate oxygen reduction by releasing more photogenerated electrons, achieving photocurrent enhancement. The developed PEC sensor had a wide detection range, from 10 ng L−1 to 10 mg L−1, with a detection limit of 5.47 ng L−1. Furthermore, the sensor was successfully applied to monitor p-ASA in simulated natural water and swine manure lixivium. This study paved the way for the design of more efficient PEC sensors for environmental monitoring.
研究领域:
环境科学
·
材料科学
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产品关联
DOI
高影响因子
SENSORS AND ACTUATORS B-CHEMICAL
·
2025
·
IF 7.7
Yani Liu,Haoyu Chen,Lin Chai,Jing Liu,Shu Huang,Feng Liu,Xiaohua Zhu,Youyu Zhang,Meiling Liu,Shouzhuo Yao
The emergence of various nanozymes has revolutionized approaches to detecting total antioxidant capacity (TAC) in food and biological samples; however, the precise quantification of specific antioxidant species such as ascorbic acid (AA) and glutathione (GSH) continue to present significant challenges. Inspired by the functional characteristics of oxidoreductases, we have developed Cu-CeO₂ nanoparticles adorned PCN-224, which exhibit multiple mimetic behaviors, including oxidase (OXD), ascorbate oxidase (AAO), and glutathione peroxidase (GPx)-like activities. This innovative PCN-224@Cu-CeO 2 is designed for the quantitative evaluation of TAC in food, pharmaceuticals, and biological samples. Simultaneously, it enables the accurate determination of AA and GSH levels with favorable selectivity. The integration of nanozymes onto metal-organic frameworks significantly enhances both stability and catalytic efficiency. Furthermore, utilizing the multi-mimetics activity of the same materials simplifies the biosensing processes for TAC and individual antioxidants in tablets, beverages, fruits, and cells, thereby considerably diminishing experimental intricacy. Our findings not only advance the development and applications of novel nanozymes with exceptional multi-mimetic properties but also tackle selectivity challenges associated with colorimetric detection platforms that rely on oxidase and peroxidase activities.
研究领域:
生物化学
·
食品科学
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分析化学
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产品关联
DOI
高影响因子
JOURNAL OF ALLOYS AND COMPOUNDS
·
2023
·
IF 6.2
Min Xie,Qiaozhen Xu,Tao Lv,Hong Liu
The search for effective and highly selective photocatalysts for CO 2 transformation is exceptionally desirable yet challenging. Herein, a novel BiVO 4 @PCN-224(Cu) heterostructure was constructed by growing BiVO 4 nanosheets on the surface of PCN-224(Cu) rods for visible-light-driven CO 2 photoreduction. The obtained BiVO 4 @PCN-224(Cu) heterostructure could selectively reduce CO 2 into CO in the absence of sacrificial reagents. The CO yield over the optimized sample reached 70.5 μmol g −1 h −1 (corresponding to an apparent quantum yield of 0.42% at 450 nm), a 5.1-fold increase over pristine PCN-224(Cu). The boosted activity of the hybrid could be credited to the S-scheme heterojunction formed at the interface of PCN-224(Cu) and BiVO 4 , which facilitated the separation of photogenerated charges and ameliorated the redox capability. In-situ XPS and hydroxyl radical determination confirmed the S-scheme charge transfer mode. This study provides a new strategy for constructing S-scheme heterojunctions involving metalloporphyrin-based metal-organic frameworks for high-performance CO 2 conversion.
研究领域:
材料科学
·
环境科学
·
化学
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF CHROMATOGRAPHY A
·
2024
·
IF 3.8
Zirou Wang,Sitian Gu,Yu Ma,Huixiao Duo,Wei Wu,Qingli Yang,Xiudan Hou
An efficient PCN-224/graphene aerogel modified silica (PCN-224/GA@Sil)-based extraction method was established for monitoring the degradation process of two organophosphorus pesticides (OPPs) in juice. PCN-224/GA@Sil exhibited higher surface area (307.35 m 2 g -1 ) than graphene oxide modified silica (254.09 m 2 g -1 ). The introduction of PCN-224 endowed the sorbent with excellent adsorption specificity towards OPPs due to the ZrˑˑˑS/O coordination bond. PCN-224 exhibited relatively higher theoretical adsorption energies of PCN-224 towards fenitrothion and fenthion were 0.68 eV and -0.31 eV. The established PCN-224/GA@Sil-HPLC method showed the linearity of 0.2–500 μg L -1 for analytes. The matrix effects in juice were 9.68 % and 3.61 % for fenitrothion and fenthion. Finally, it was used for the sample pretreatment of juice preventing interference from food matrices to monitor the degradation of two OPPs. A combination method of ultrasound and xenon lamp was adopted to degrade fenitrothion and fenthion displaying the synergistic effect ( SE =2.12, 1.39).
研究领域:
分析化学
·
环境科学
·
食品科学
·
材料科学
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产品关联
DOI
PubMed
高影响因子
MICROCHEMICAL JOURNAL
·
2025
·
IF 5.1
Xiudan Hou,Zirou Wang,Hui Yu,Yufei Liu,Qingli Yang
Excess residues of organophosphorus pesticides in traditional Chinese medicinal herbs has been driving the development of rapid and specific detection methods. Herein, a dual-mode sensing platform was established for the simultaneous determination of glyphosate and profenofos using the colorimetric and fluorescence sensors, respectively. A Zn-incorporated porous coordination network-224 (PCN-224) was prepared to selectively adsorb glyphosate based on the coordination effect of Zr and phosphate ion, which would inhibit the peroxidase-like activity of PCN-224(Zn). An aptamer-modified nitrogen-carbon quantum dots (N-CQDs) was used to specifically recognize profenofos, further adopting the quenching effect of PCN-224(Zn) towards N-CQDs to realize the quantitative analysis. The colorimetric sensing mechanism was also studied. Coupled with a smartphone application, the established method exhibited the linearity of 0.06–3.1 μg mL −1 (glyphosate), and 0.02–3.9 μg mL −1 (profenofos). The matrix effect was 100.58 % and 95.46 % in Angelica sinensis and Codonopsis , presenting a new horizon for the multi-model sensor in real samples.
研究领域:
分析化学
·
环境科学
·
药学
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产品关联
DOI
高影响因子
ACS Applied Nano Materials
·
2023
·
IF 5.9
Longbao Zhu,Ting Gui,Ping Song,Wanzhen Li,Jun Wang,Chengrui Hu,Yuanchen Sun,Fei Ge,Weiwei Zhang
Chemodynamic therapy (CDT) is a highly promising tumor treatment modality that uses the Fenton reaction to convert intracellular hydrogen peroxide (H2O2) into cytotoxic hydroxyl groups (•OH). However, the therapeutic effects of CDT have been restricted by weak acidic pH values, insufficient H2O2 levels, and high glutathione (GSH) concentrations in the tumor microenvironment (TME). In this study, to construct PCN-224-Pt/GOD, porphyrin-based metal–organic framework nanoparticles (PCN-224) were used as the carrier to load Pt and glucose oxidase (GOD). The surface of PCN-224-Pt/GOD was covered with manganese dioxide (MnO2) to fabricate the multifunctional composite nanoparticles PCN-224-Pt/GOD@MnO2 (P–P/GOD@Mn). P–P/GOD@Mn was used to increase H2O2 levels and to decrease GSH levels for combined CDT and starvation therapy. As a result, we developed P–P/GOD@Mn nanoparticles (diameter, approximately 280 nm) with favorable size and biocompatibility. Under simulated TME conditions, P–P/GOD@Mn nanoparticles could catalyze H2O2 to generate cytotoxic hydroxyl radicals (•OH), consume glutathione (GSH), and decompose H2O2 to generate oxygen (O2). Cellular toxicity assay results showed that P–P/GOD@Mn killed MCF-7 cells in the TME, with a rate of 77%. The results of tumor-bearing mouse experiments proved that P–P/GOD@Mn nanoparticles could significantly suppress tumor cell growth, which shows the great potential of this entity in CDT and its possibility in bimodal cancer therapy.
研究领域:
生物医学工程
·
肿瘤治疗
·
纳米医学
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产品关联
DOI
高影响因子
ACS Applied Materials & Interfaces
·
2021
·
IF 9.229
Yuheng Bao,Jifan Chen,Huiqiang Qiu,Cong Zhang,Pintong Huang,Zhengwei Mao,Weijun Tong
Sonodynamic therapy (SDT) is a promising method for tumor treatment, but self-quenching property, low loading efficiency of sonosensitizers, and hypoxia tumor microenvironment (TME) hinder the efficiency of SDT. Herein, an erythrocyte membrane (EM)-camouflaged metal–organic framework (MOF) of PCN-224 nanoparticles (NPs) integrated with platinum (Pt) NPs as well as glucose oxidase (GOx) has been developed to overcome these limits. Porphyrin-based PCN-224 NPs are synthesized as a sonosensitizer with a large amount of well-organized porphyrin molecules while simultaneously acting as the nanocarriers (NCs) for Pt NPs and GOx. When the NCs are internalized by tumor cells, Pt NPs on their surface are able to utilize endogenous hydrogen peroxide (H2O2) to produce oxygen for the relief of tumor hypoxia, thus enhancing the SDT effect. After EM cloaking, the longer circulation time can improve biocompatibility in vivo and enhance accumulation in tumor tissue. Loaded GOx is beneficial to local glucose consumption and can realize the tumor starvation therapy effect. Consequently, these multifunctional NCs show amplified synergistic therapeutic effects of tumor SDT and starvation therapy, which can efficiently inhibit the tumor growth.
研究领域:
生物医学工程
·
肿瘤治疗学
·
纳米医学
✓ 已验证
DOI
PubMed
高影响因子
Small Structures
·
2025
·
IF 11.3
Jiaojiao Fan,Jianmin Chen,Wenji Li,Zhongxing Zhao,Zhenxia Zhao
Converting CO 2 into high-value-added products via “artificial photosynthesis” under mild conditions is a promising yet challenging strategy for developing efficient photocatalysts. This study reports a simple two-step solvothermal approach to fabricate the dual-metal–organic framework (MOF) nanocomposite NH 2 -UiO-66@PCN-224 (NU-66@PCN-224) with tightly integrated interfaces, which achieves efficient CO 2 to CO photocatalytic reduction under light irradiation. The epitaxially grown PCN-224, composed of Zr 6 clusters and tetrakis (4-carboxyphenyl) porphyrin (TCPP), serves as a shell layer and a visible light-absorbing antenna, thereby broadening the light absorption range of the composite material. Moreover, the tightly integrated interfaces of NU-66@PCN-224 enhance the mobility of photogenerated charge carriers, consequently enhancing its capability for CO 2 catalytic reduction. As a result, the combination of NU-66 and PCN-224 retains their individual advantages while achieving a synergistic enhancement of both adsorption and catalysis, further improving the photocatalytic performance. The as-prepared NU-66@PCN-224 catalyst exhibits outstanding photocatalytic performance, yielding 74.6 μmol g −1 h −1 of CO under irradiation without sacrificial agents or photosensitizers. This work demonstrates a straightforward and effective method for designing MOF-on-MOF photocatalysts with enhanced photoactivity.
研究领域:
材料科学
·
纳米技术
·
环境科学
·
光催化
·
能量转换
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）