A new electrochemical sensing strategy for echinacoside based on an original nanocomposite
In this work, a brand new nanocomplex (denoted as [email protected] ) is elaborately designed and successfully synthesized meaning the in-situ assembly of porous-morphology Zn-based MOFs (MOF-5) onto the as-prepared PDDA-rGO-Ni (PGN for short) nanocomposites. When this nanocomplex contributes to construct the electrochemical sensor ( [email protected] /GCE), it presents a highly-sensitive response towards echinacoside, and the first measurement for echinacoside by electrochemistry accordingly evolves forward. The crystallization processes are investigated by FT-IR instrument and XRD analysis, as well as micro-morphology of modified materials is visible upon SEM and TEM. Adorably, a novel ratiometric sensor was progressively fabricated by encapsulating methylene blue (MB) molecules into cubic MOF-5 framewoks (MB encased [email protected] /GCE), and apart from assisting in establishing the analysis method with extreme accuracy and favorable practicality, it dose devote a wider linear scale and a lower detection limit than that [email protected] /GCE has given out. Drawn from the developed calibration curve using differential pulse voltammetry (DPV) technique, the peak intensity ratio (I Ech /I MB ) varies linearly with increased echinacoside concentration in the range of 3.0 × 10 −8 – 1.0 × 10 −6 mol L −1 with limit of detection (LOD) reaching 1.0 × 10 −8 mol L −1 (S/N = 3). Additionally, the proposed assay method has been employed to detect echinacoside in real sample sliced cistanche with satisfactory results.
危险品化学品经营许可证（带存储）