ChemistrySelect
·
2025
·Vol. 10
·期 37
·e04026
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IF 2
Hongwei Li,Zhibin Liu,Pengju Lei,Jichong Xia,Shoudeng Wang,Guixian Li,Xinhong Zhao,Dong ji
A PEG-400-assisted impregnation-precipitation method synthesized 50 wt% Ni/AC catalysts for dinitrotoluene (DNT) hydrogenation. Optimal PEG-400 dosage (0.4 g) suppressed Ni agglomeration via steric hindrance, yielding uniform 10.9-nm Ni nanoparticles and mesopores (12.24 nm). This enhanced dispersion and mass transfer, achieving complete DNT conversion in 5 min under mild conditions (120 °C, 2.1 MPa H 2 ) with 99.99% TDA selectivity and zero tar. The catalyst retained > 95.5% conversion and > 97.3% selectivity over 10 cycles, demonstrating exceptional stability. PEG's dual role in structural control and pore engineering effectively addresses the dispersion challenges inherent to high-loading catalysts. Graphical PEG-400 directs the synthesis of a 50 wt% Ni/AC catalyst via impregnation-precipitation. Optimal PEG dosage (0.4 g) enables steric hindrance control, yielding uniform 10.9-nm Ni nanoparticles and mesopores. This catalyst achieves complete DNT hydrogenation to TDA in 5 min (120 °C; 2.1 MPa H 2 ) with > 99.99% selectivity and zero tar, retaining high performance over 10 cycles.
研究领域:
催化化学
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材料化学
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化学工程
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纳米催化
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有机合成
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产品关联
DOI
高影响因子
CHEMICAL PHYSICS LETTERS
·
2018
·
IF 1.686
Shiyu Zuo,Haiming Xu,Wei Liao,Lei Sun,Qiang Li,Jie Zan,Binyang Zhang,Dongya Li,Dongsheng Xia
In this study, g-C 3 N 4 Cu 2 O was successfully synthesized in the presence of PEG-400 surfactant via an acid treatment hydrothermal method and a high-temperature calcination method. The structures and properties of as-synthesized samples were characterized using a range of techniques, such as XPS, TEM, PL and BET. The g-C 3 N 4 Cu 2 O heterojunction exhibits the enhanced photocatalytic performance and high stability. It is revealed that the addition of PEG can promote the heterojunction effect of g-C 3 N 4 Cu 2 O, effectively improving the crystallinity and specific surface area of the photocatalyst, separation efficiency of photocarriers, and light absorption, thus enhancing the photocatalytic performance.
研究领域:
材料科学
·
环境科学
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DOI
高影响因子
JOURNAL OF CHEMICAL AND ENGINEERING DATA
·
2025
·
IF 2.1
Qingxia Zhou,Yanrong Cheng,Delan Ge,Xia Guo
PEG/salt aqueous two-phase systems (ATPSs) are the most common ATPSs because they are nontoxic, biocompatible, and inexpensive; however, the limited polarity difference between the two phases hinders their application. Although increasing the molecular weight of PEG can increase the polarity difference between the two phases, the significant viscosity of the PEG phase makes mass transfer difficult once the PEG molecular weight is too high. In the present study, we focus on enhancing the performance of low-molecular-weight PEG (PEG 400)/salt ATPS by using different ionic surfactants as adjuvants; the surfactants include anionic surfactants sodium dodecyl sulfate and sodium dodecyl benzenesulfonate, cationic surfactant dodecyl trimethylammonium bromide, and zwitterionic surfactant N-dodecyl-N, N-dimethyl-3-ammonio-1-propanesulfonate. It is found that all of these surfactants can promote the PEG 400/salt ATPS formation, but their effects on the ATPS extraction performance are different. By using tryptophan and vanillin as model extracts, it is found that the anionic and zwitterionic surfactants significantly enhance the extraction performance of PEG 400/salt ATPS, while the cationic surfactant significantly reduces the ATPS extraction performance. These results illustrate the potential of anionic and zwitterionic surfactants as adjuvants in enhancing the performance of low-molecular-weight PEG/salt ATPS.
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DOI
高影响因子
CATALYSIS LETTERS
·
2021
·Vol. 152
·期 9
·2688-2694
·
IF 3.186
Cai Mingzhong,Liu Rong,Xu Caifeng,Huang Bin
Pd(OAc) 2 /XPhos–SO 3 Na in a mixture of poly(ethylene glycol) (PEG-400) and water is shown to be a highly efficient catalyst for the cyanation of aryl chlorides with potassium ferrocyanide. The reaction proceeded smoothly at 100 or 120 ºC with K 2 CO 3 or KOAc as base, delivering a variety of aromatic nitriles in good to excellent yields. The isolation of the crude products is facilely performed by extraction with cyclohexane and more importantly, both expensive Pd(OAc) 2 and XPhos–SO 3 Na in PEG-400/H 2 O system could be easily recycled and reused at least six times without any apparent loss of catalytic efficiency. Graphical Abstract Palladium-catalyzed cyanation of aryl chlorides with potassium ferrocyanide leading to aryl nitriles by using Pd(OAc) 2 /XPhos–SO 3 Na/PEG-400/H 2 O as a highly efficient and recyclable catalytic system is described.
研究领域:
有机化学
·
绿色化学
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DOI
高影响因子
CATALYSIS LETTERS
·
2022
·Vol. 153
·期 3
·732-739
·
IF 2.936
Li Jianying,Liu Rong,Ye Qian,Cai Mingzhong
[RuCl 2 ( p -cymene)] 2 in a mixture of poly(ethylene glycol) (PEG-400) and water is shown to be a highly efficient catalyst for the annulation of N -methoxybenzamides with alkynes. The reaction proceeded smoothly at 60 ºC with MesCO 2 K as a cocatalytic additive under external oxidant-free conditions, delivering a variety of substituted isoquinolones in mostly good to excellent yields. The isolation of the crude products can be easily performed by extraction with diethyl ether and more importantly, [RuCl 2 ( p -cymene)] 2 /PEG-400/H 2 O system could be facilely recycled and reused more than six times without any apparent loss of catalytic efficiency. Graphical Abstract
Ruthenium-catalyzed annulation of N -methoxybenzamides with alkynes leading to isoquinolones by using [RuCl 2 (p-cymene)] 2 /PEG-400/H 2 O as a highly efficient and recyclable catalytic system is described.
研究领域:
有机化学
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催化化学
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产品关联
DOI
高影响因子
Nano-Micro Letters
·
2022
·Vol. 14
·期 1
·1-18
·
IF 23.655
Chen Yangwu,Ma Dingtao,Ouyang Kefeng,Yang Ming,Shen Sicheng,Wang Yanyi,Mi Hongwei,Sun Lingna,He Chuanxin,Zhang Peixin
Large volumetric expansion of cathode hosts and sluggish transport kinetics in the cathode–electrolyte interface, as well as dendrite growth and hydrogen evolution at Zn anode side are considered as the system problems that cause the electrochemical failure of aqueous Zn-vanadium oxide battery. In this work, a multifunctional anti-proton electrolyte was proposed to synchronously solve all those issues. Theoretical and experimental studies confirm that PEG 400 additive can regulate the Zn 2+ solvation structure and inhibit the ionization of free water molecules of the electrolyte. Then, smaller lattice expansion of vanadium oxide hosts and less associated by-product formation can be realized by using such electrolyte. Besides, such electrolyte is also beneficial to guide the uniform Zn deposition and suppress the side reaction of hydrogen evolution. Owing to the integrated synergetic modification, a high-rate and ultrastable aqueous Zn-V 2 O 3 /C battery can be constructed, which can remain a specific capacity of 222.8 mAh g −1 after 6000 cycles at 5 A g −1 , and 121.8 mAh g −1 even after 18,000 cycles at 20 A g −1 , respectively. Such “all-in-one” solution based on the electrolyte design provides a new strategy for developing high-performance aqueous Zn-ion battery.
研究领域:
电化学
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材料科学
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能源存储
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DOI
PubMed
高影响因子
INTERNATIONAL JOURNAL OF PHARMACEUTICS
·
2020
·
IF 4.845
Jian Liu,Qilong Wang,Emmanuel Omari-Siaw,Michael Adu-Frimpong,Jing Liu,Ximing Xu,Jiangnan Yu
In this study, we sought to overcome the poor solubility and bioavailability of bismethoxycurcumin (BDMC) by fabricating a BDMC-loaded self micro-emulsifying system (BDMC-SMEDDS). Solubility and compatibility tests, pseudo-ternary phase diagrams (PTPDs) as well as d-optimal concept was applied to design the formulation. The assessment of the prepared BDMC-SMEDDS in-vitro mainly included droplet size (DS) and entrapment efficiency (EE) determination, morphology, drug release and stability testing. Besides, the in vivo behavior was also evaluated after oral administration of BDMC-SMEDDS to rats. The optimal formulation was found to compose of Kolliphor EL (K-EL, emulsifier , 645.3 mg), PEG 400 (co-emulsifier, 147.2 mg), ethyl oleate (EO, oil, 207.5 mg) and BDMC (50 mg). The BDMC-SMEDDS with satisfactory stability had a mean size of 21.25 ± 3.23 nm and EE of 98.31 ± 0.32%. Roughly 70% of BDMC was released from BDMC-SMEDDS within 84 h compared with <20% from the free BDMC. More importantly, the in-vivo behavior of BDMC-SMEDDS showed that the AUC (0-12h) and plasma concentration of BDMC increased substantially as compared to the free BDMC. Altogether, BDMC-SMEDDS has the potential to enhance the solubility and bioavailability of BDMC and could be applied in the clinics.
研究领域:
药剂学
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药物递送系统
·
药代动力学
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DOI
高影响因子
Applied Materials Today
·
2024
·
IF 7.2
Tianyu Yuan,Dongdong Liu,Qian Li,Meng Wei,Yingbao Sun,Hua Xie,Lina Du,Bochuan Yuan,Pei Deng,Yanli Guo,Yiguang Jin
Corrosive esophagitis (CE) is a severe disease caused by accidental or suicidal ingestion of corrosive chemical agents, leading to serious esophageal stenosis or fibrosis. However, the effective and safe treatment of CE is lacking. Here, a melatonin esophagus stent (MES) was prepared using the stereolithography three-dimensional (3D) printing technology with melatonin, polyethylene glycol diacrylate (PEGDA), polyethylene glycol (PEG) 400, and other additives. The MESs with the Roman columns, caduceus, Pagoda, and mace morphologies were designed and printed, respectively. Pagoda MESs exhibited good mechanical properties, retained in the esophagus for more than 24 h, and showed rapid melatonin release. MESs had high in vitro and in vivo safety. More importantly, the implanted MES was broken down into fragments in the gastrointestinal tract and then completely evacuated from the rat body. The CE rat model was established by injecting a strong alkaline solution into the esophagus. The Pagoda MES was conveniently implanted at the injury position, which remarkably alleviated the CE symptoms, reduced inflammation, and prevented esophagus stenosis and fibrosis. 3D-printed Pagoda MESs hold promise for the treatment of CE.
研究领域:
生物医学工程
·
药学
·
材料科学
·
组织工程
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产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）