RSC Advances
·
2015
·Vol. 5
·期 120
·99418-99424
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IF 3.84
Jinda Fang,Ke Zhang,Jingwei Jia,Zhengke Wang,Qiaoling Hu
To improve the drug-loading capacity and control the initial release of amphiphilic drug carriers, a series of N-phthaloyl-chitosan-g-(PEO–PLA–PEO) compounds were synthesized with well-defined structures. The self-assembly behavior of copolymers in aqueous solutions was confirmed by various techniques such as fluorescence spectrometry, dynamic light scattering, and transmission electron microscopy. The results demonstrated that the micellization behavior of graft copolymers was different from that of their linear counterparts. The micelle sizes of the graft copolymers could be tuned with chemical composition as well as temperature. Furthermore, when hydrophobic indomethacin was loaded into the micelles, the graft copolymer micelles trapped more indomethacin than PEO–PLA–PEO micelles, facilitating the in vitro control of the initial burst release of the drug. Drug release could be controlled in vitro by simply altering the EO/LA ratio of the grafting chains. The graft copolymer showed low cytotoxicity to 293T cells, indicating its great potential application for drug delivery.
研究领域:
生物材料学
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药剂学
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DOI
高影响因子
RSC Advances
·
2017
·Vol. 7
·期 7
·4000-4010
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IF 3.108
Yongjing Xu,Liming Zou,Hongwei Lu,Tingjie Kang
The selection of non-hazardous solvent systems is an important factor that can significantly influence fiber formation during polymer electrospinning. In this paper, poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV)/polyethylene oxide (PEO) has been electrospun using different solvent systems to investigate the influence of different solution properties on nanofiber morphology and diameter, the thermal and mechanical properties, as well as the degradation kinetics of the electrospun fibers. The morphology, thermal and mechanical properties of PHBV/PEO electrospun fibers were characterized using scanning electron microscopy (SEM), thermogravimetric analysis (TG) and differential scanning calorimetry (DSC), and a universal testing machine, respectively. The results showed that the binary-solvent system (dichloromethane/ethanol DCM/EtOH) gave the finest defect-free fibers, and exhibited the best thermal and mechanical properties of all the single solvents (chloroform (CHL), dichloromethane (DCM)). Therefore, the effect of DCM/EtOH in different ratios on PHBV/PEO electrospun fibers was studied in detail. In brief, the DCM/EtOH solvent system was considered to be the best candidate for PHBV/PEO for electrospinning.
研究领域:
材料科学
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生物医学工程
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DOI
高影响因子
Journal of Energy Storage
·
2023
·
IF 9.4
Lin Yang,Hong Zhang,Enjie Xia,Yanmei Wu,Zhicheng Li
The organic/inorganic composite solid electrolytes (CSEs) for solid-state lithium batteries (LIBs) have attracted much attention for the possible advantages such as good interfacial compatibility, low cost, high efficiency and safety, etc. In this work, Li 2 ZrO 3 inorganic Li-ion conductor is first time used as electrolyte filler for fabricating organic/inorganic CSE films. The CSE with 20 % (weight percentage) of Li 2 ZrO 3 powder in polyethyleneoxide (PEO) exhibits high comprehensive performance with room-temperature conductivity of 6.76 × 10 −6 S cm −1 , electrochemical window of 4.2 V and ionic transference number of 0.20. The introduction of Li 2 ZrO 3 obviously reduces the interfacial resistance between PEO and Li metal, and enhances the CSE stability by reducing the decomposition of LITFSI in CSE film. The assembled flexible Li/CSE/NCM811 solid-state LIBs deliver high rate capability and cycling stability. Li 2 ZrO 3 /PEO CSE is a promising electrolyte for flexible solid-state LIBs.
研究领域:
材料科学
·
能源存储技术
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DOI
高影响因子
MATERIALS LETTERS
·
2021
·
IF 3.423
Qi Han,Yan Li,Xiaopeng Lu,Di Mei,Qianqian Chen,Tao Zhang,Fuhui Wang
Antibacterial plasma electrolytic oxidation (PEO) coatings have been fabricated by in-situ incorporation of Ag particles on pure Mg. It was found that the Ag particles have been partly oxidized and incorporated into the layer during coating formation process. Ag containing PEO coatings can strongly inhibit the growth of S. aureus and the antibacterial efficiency of the coatings is mainly associated with the Ag concentration in the layer. The antibacterial rate of the coating reaches 99% and is maintained to be stable when sufficient Ag particles (above 1 wt%) are incorporated into the layer.
研究领域:
材料科学
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生物材料
·
表面工程
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DOI
高影响因子
CORROSION SCIENCE
·
2022
·
IF 7.72
Haiyang Wang,Yulai Song,Xuegang Chen,Guodong Tong,Linyang Zhang
The MgAl-LDHs film was in situ grown on the PEO film of magnesium alloy by hydrothermal growth method, and the PEO-LDHs-SDS composite film modified by sodium dodecyl sulfate (SDS) was further prepared. The results show that compared with the single-layer PEO film, the PEO-LDHs-SDS composite film exhibits excellent short-term and long-term protection performance, which can be attributed to the blocking effect of the superhydrophobic surface of the composite film, the sealing effect of LDHs on the micropores of the PEO film, and the readsorption and corrosion inhibition of SDS anions.
研究领域:
材料科学
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腐蚀工程
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表面工程
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DOI
高影响因子
Materials
·
2024
·Vol. 17
·期 13
·3094
·
IF 3.1
Chengjun Lin,Yaoyi Huang,Dingrong Deng,Haiji Xiong,Bin Lu,Jianchun Weng,Xiaohong Fan,Guifang Li,Ye Zeng,Yi Li,Qihui Wu
Replacing the flammable liquid electrolytes with solid ones has been considered to be the most effective way to improve the safety of the lithium batteries. However, the solid electrolytes often suffer from low ionic conductivity and poor rate capability due to their relatively stable molecular/atomic architectures. In this study, we report a composite solid electrolyte, in which polyethylene oxide (PEO) is the matrix and Li6.4La3Zr1.45Ta0.5Mo0.05O12(LLZTMO) and Li6.4La3Zr1.4Ta0.6O12(LLZTO) are the fillers. Ta/Mo co-doping can further promote the ion transport capacity in the electrolyte. The synthesized composite electrolytes exhibit high thermal stability (up to 413 °C) and good ionic conductivity (LLZTMO–PEO 2.00 × 10−4S·cm−1, LLZTO–PEO 1.53 × 10−4S·cm−1) at 35 °C. Compared with a pure PEO electrolyte, whose ionic conductivity is in the range of 10−7~10−6S·cm−1, the ionic conductivity of composite solid electrolytes is greatly improved. The full cell assembled with LiFePO4as the positive electrode exhibits excellent rate performance and good cycling stability, indicating that prepared solid electrolytes have great potential applications in lithium batteries.
研究领域:
材料科学
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能源存储技术
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产品关联
DOI
PubMed
高影响因子
CORROSION SCIENCE
·
2021
·
IF 7.205
Dongdong Zhang,Feng Peng,Jiajun Qiu,Ji Tan,Xianming Zhang,Shuhan Chen,Shi Qian,Xuanyong Liu
Herein, a novel smart chemical strategy for regulating the corrosion reaction to reinforce the plasma electrolytic oxidation (PEO) coating on magnesium by amorphous MnOOH is proposed. The MnOOH film could provide PEO coating with both physical shielding and chemical active healing abilities. During corrosion process, MnOOH spontaneously reacts with the corrosion-produced Mg 2+ and OH – to form layered double hydroxides , resulting in high improvement of the long-term anti-corrosion of PEO coating. Moreover, the PEO/MnOOH coating presented a certain self-healing ability for scratches, and could be used for repairing corrosion defects on further coated films.
研究领域:
材料科学
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化学工程
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DOI
高影响因子
Journal of Materials Chemistry B
·
2015
·Vol. 3
·期 20
·4259-4271
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IF 4.726
Chunhuan Shi,Zhiqing Zhang,Fang Wang,Xiaoqing Ji,Zhongxi Zhao,Yuxia Luan
There are two major hurdles for the current anti-cancer drug delivery systems. One is the emergence of multidrug resistance (MDR) and the other is the conflict between long-circulation and cellular uptake. In the present study, the anticancer drug docetaxel (DTX) was successfully loaded into three series of micelles via self-assembly using a mixture of PEO–PPO–PCL and D-α-tocopheryl poly(ethylene glycol) 1000 succinate (TPGS), for the purpose of prolonging the blood circulation time as well as overcoming MDR of DTX. Three series of copolymers with different PCL molecular weights, PEO68–PPO34–PCL9, PEO68–PPO34–PCL18 and PEO68–PPO34–PCL36, were synthesized. The prepared spherical mixed micelles (MM) were found to possess nanoscale size (25–135 nm). The PEO–PPO–PCL/TPGS mixed micelles had a low critical micelle concentration (∼10−6 g mL−1) and a low hemolysis rate (<5%), which has proved that they are safe for use in vivo. Moreover, they had obvious sustained release behavior in vitro and a longer circulation time than free DTX in vivo. The P-gp inhibition assay, cellular uptake and MTT assay in cancer cells exhibited that DTX-loaded MM could overcome MDR, show higher cellular uptake and higher antitumor efficacy than free DTX. The IC50 values demonstrated that the three series of DTX-loaded MM were 69, 82 and 100 fold effective than free DTX after 72 h treatment with MCF-7 cells, respectively. Therefore, these results demonstrated that the prepared DTX-loaded MM provide desirable application in cancer chemotherapy.
研究领域:
药学
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肿瘤学
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生物材料
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产品关联
DOI
PubMed
高影响因子
Journal of Materials Chemistry A
·
2019
·Vol. 7
·期 27
·16425-16436
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IF 10.733
Zeya Huang,Wanying Pang,Peng Liang,Zhehui Jin,Nicholas Grundish,Yutao Li,Chang-An Wang
A garnet-type solid-state electrolyte Li6.4La3Zr1.4Ta0.6O12 (LLZTO) was modified using dopamine to improve the wettability of LLZTO with PEO, allowing 80 wt% LLZTO to be uniformly dispersed in 20 wt% PEO/LiTFSI polymer electrolyte. Transmission electron microscopy and Fourier transform infrared spectroscopy confirmed a 4–5 nm thick polydopamine (PDA) layer coating on LLZTO nanoparticles. The composite LLZTO@PDA/PEO electrolyte was synthesized using a solvent casting method. The composite electrolyte has good compatibility and adhesion with both positive and negative electrodes of Li-ion batteries owing to the superior wetting capability of dopamine. This property allows for improved interfacial contact at the electrode/solid electrolyte interface which can decrease the overall resistance of the battery. With dopamine modification, the conductivity of the composite electrolyte at 30 °C increased from 6.3 × 10−5 S cm−1 to 1.1 × 10−4 S cm−1, and the interfacial resistance between the composite electrolyte and a metallic lithium anode decreased from 308 Ω cm2 to 65 Ω cm2 at 50 °C. The composite electrolyte also demonstrated improved thermal stability.
研究领域:
材料科学
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电化学
·
能源存储
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DOI
高影响因子
ELECTROCHIMICA ACTA
·
2015
·
IF 4.504
Bo Liang,Siqi Tang,Qingbai Jiang,Chuangsheng Chen,Xu Chen,Shengliang Li,Xuehui Yan
This paper presents the preparation and characterization of a series of PEO-PMMA composites containing different lithium salts (LiClO 4 or LiTFSI) with or without nano-Al 2 O 3 . Nano-Al 2 O 3 is added to the polymer electrolytes to alter the morphology, ionic conductivity , interfacial and thermal shrinkage properties. Nano-Al 2 O 3 can effectively improve the stability of the polymer electrolyte membrane interface. The tensile strength of the PEO-PMMA-LiTFSI-Al 2 O 3 electrolyte membrane is 3.24 MPa at room temperature . The study shows that the ion conductivities at room temperature for PEO-PMMA-LiTFSI (EO/Li + = 10) and PEO-PMMA-LiTFSI-Al 2 O 3 (EO/Li + = 10) are 6.71 × 10 −7 S/cm and 9.39 × 10 −7 S/cm, respectively. A good dimensional stability was observed for PEO-PMMA-LiTFSI with a thermal shrinkage of 8.7%. The electrochemical windows of PEO-PMMA-LiTFSI and PEO-PMMA-LiTFSI-Al 2 O 3 are all stable up to 4.6 V versus Li + /Li, which makes them good electrolyte candidates of lithium ion batteries with high-potential cathodes.
研究领域:
材料科学
·
电化学
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产品关联
DOI
高影响因子
SURFACE & COATINGS TECHNOLOGY
·
2021
·
IF 4.158
Zefei Yu,An Du,Chenyang Wang,Ruina Ma,Yongzhe Fan,Xue Zhao,Xiaoming Cao
Herein, a ZnO-doped plasma electrolytic oxidation (PEO) composite coating was prepared on the surface of a 1060 Al alloy by adding ZnO nanoparticles (ZnO-NPs) to the composite electrolytes of alkaline sodium silicate (Na 2 SiO 3 ) and sodium hexametaphosphate ((NaPO 3 ) 6 ). To efficiently investigate the coating's microstructure, the detached PEO coating was prepared without damage via an electrochemical method. The morphology and phase composition of the PEO coating were analyzed using scanning electron microscopy (SEM), energy-dispersive X-ray spectroscopy (EDS), transmission electron microscopy (TEM), and X-ray diffraction (XRD), and an incorporation model of ZnO-NPs was established. The results showed that the addition of ZnO-NPs slightly prolonged the anodic oxidation time and increased the breakdown voltage, whereas the working voltage and final voltage decreased slightly. The XRD results indicated that although the addition of ZnO-NPs did not result in the production of Zn-containing phases, it affected the formation and transformation reactions of other phases. SEM micrographs of the fractured cross-section of detached coating and coating/substrate interface indicated that the ZnO-NPs did not enter the interface layer, nor did it participate in the formation of the cap structure at the interface. Based on the experimental results and the “cascade discharge” model, an incorporation model of ZnO-NPs in PEO has been proposed.
研究领域:
材料科学
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表面工程
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DOI
高影响因子
TRIBOLOGY INTERNATIONAL
·
2024
·
IF 6.1
An Liu,Song Gao,Shan Du,Hailin Lu,Junde Guo
Plasma electrolytic oxidation (PEO) has demonstrated significant enhancements in the mechanical properties and corrosion resistance of titanium alloys. Despite these advantages, the presence of micropores and microcracks in the coating can still detrimentally impact tribological properties. This paper introduces a novel approach involving the in-situ growth of a surface structure. The resulting interface structure exhibits outstanding tribological properties under a load of 3 N and a speed of 1.5 cm/s. In contrast to prior studies, improvements are made to the electrical parameters and electrolyte formula of Plasma electrolytic oxidation, facilitating the in-situ growth of MoSe 2 . This results in the formation of a lubricating layer and a robust TiO 2 ceramic coating with excellent adhesion. A systematic analysis of friction, wear characteristics, reveals that MoSe 2 in situ grow on the surface of the PEO coating, within micropores, microcracks, and crater structures after hydrothermal treatment. This process significantly enhances the microporous structure of the coating, with the MoSe 2 film forming a dense and uniform interlocking layer with the PEO lower layer. Dry friction test experiments demonstrate a 33.7% reduction in friction coefficient and a 29% decrease in wear rate compared to the PEO sample, indicating the synergistic effect between the MoSe 2 film and the PEO coating.
研究领域:
材料科学
·
表面工程
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产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）