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PGS/PLLA@PNIPAM

Journal of Engineered Fibers and Fabrics · 2021 · IF 1.573

Preparation and characterization of PGS/PLLA@PNIPAM core-shell nanofiber membrane by electrospinning and surface ATRP grafting

Qijian Niu,Lili Ma,Junxia Guo,Xiaoping Yang

In this study, a temperature responsive PGS/PLLA@PNIPAM core-shell nanofiber membrane was prepared by combining electrospinning with surface ATRP grafting polymer technology, in which the core layer of PGS/PLLA nanofiber was prepared by electrospinning, and then the shell layer of temperature responsive PNIPAM polymer was grafted on the nanofiber surface by ATRP reaction. In the experiment, a macromolecule-initiator PGS-Br was prepared and characterized by FTIR and 1H NMR. The surface morphology, composition, element of the core-shell nanofiber membrane were characterized by SEM, FTIR, and XPS. In addition, it is worth noting that the core-shell nanofiber membrane can respond to temperature in drug release tests.

CAS / MDL: 50-81-7 64-19-7 111-20-6 20769-85-1 2210-25-5 3030-47-5

研究领域: 材料科学 · 高分子化学 · 纳米技术 · 药物传递系统

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