ShiJie Yu,XiaoDong Xu,Liang Ma,Fei Zhao,JinLei Mao,Jing Zhang,ZhiFei Wang
The increasing complexity and difficulty of surgical procedures have led to a rise in medical errors within clinical settings in recent years. Gastrointestinal diseases, in particular, present significant medical challenges and impose substantial economic burdens, underscoring the urgent need for experiential, high-fidelity gastrointestinal surgical training tools. This study leverages patient-specific computed tomography (CT) and magnetic resonance imaging (MRI) data, combined with 3D printed manufacturing, to develop hydrogel organ models with tunable performance and tissue-mimicking softness. These properties are achieved by regulating the freeze–thaw cycles, cross-linking agents, and the concentration of incorporated antibacterial nanoparticles in DN hydrogels. Through the application of indirect 3D printing and the “sacrificial material method”, we successfully fabricate organ tissues such as the stomach, intestines, and blood vessels with high precision. In ex vivo surgical training demonstrations, these tissue-like soft hydrogels provide an effective platform for preoperative simulation and surgical training in digestive surgery, accommodating various surgical procedures and accurately simulating intraoperative bleeding. The development of advanced bionic organ models with specific and tunable characteristics based on DN hydrogels is poised to significantly advance surgical training, medical device testing, and the reform of medical education.
Anni Fu,Ziyang Qiu,Qiuxun Liu,Ye Chen,Yuxuan Hu,Ximei Liu
Solar-driven interfacial evaporation holds great promise for clean water production, particularly in seawater desalination and wastewater purification. However, the limited evaporation performance of evaporators and their incapability to degrade organic contaminants hinder their practical applications. Here, we develop a bifunctional frustum-array solar-driven evaporator with high efficiency in both seawater desalination and photocatalytic dye degradation. Our evaporator, designated as FATPE, is fabricated via a template-assisting method with Ti 3 O 5 /PVA/PAM hydrogels to create a frustum-array structure. Under 1 sun irradiance (1 kW m -2 ), FATPE achieves an exceptional evaporation rate of 4.34 kg m -2 h -1 , energy efficiency of 95.90%FATPE, as well as excellent desalination capability with a salt rejection rate exceeding 99.90% in simulated seawater with varying salinities. Furthermore, FATPE can realize efficient photocatalytic degradation of varying organic pollutants, exemplified with a methylene blue (MB) degradation rate of 85.37%. This work realizes the dual functional synergy of high-efficiency water purification and photocatalytic dye degradation, offering a promising strategy for producing clean water from seawater and dye-contaminated wastewater in coastal regions.
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