Research
·
2022
·
IF 11.036
Junchen Liu,Sen Lin,Wenzheng Li,Yanzhen Zhao,Dingkun Liu,Zhaofeng He,Dong Wang,Ming Lei,Bo Hong,Hui Wu
Noninvasive brain-computer interface (BCI) has been extensively studied from many aspects in the past decade. In order to broaden the practical applications of BCI technique, it is essential to develop electrodes for electroencephalogram (EEG) collection with advanced characteristics such as high conductivity, long-term effectiveness, and biocompatibility. In this study, we developed a silver-nanowire/PVA hydrogel/melamine sponge (AgPHMS) semidry EEG electrode for long-lasting monitoring of EEG signal. Benefiting from the water storage capacity of PVA hydrogel, the electrolyte solution can be continuously released to the scalp-electrode interface during used. The electrolyte solution can infiltrate the stratum corneum and reduce the scalp-electrode impedance to 10 kΩ-15 kΩ. The flexible structure enables the electrode with mechanical stability, increases the wearing comfort, and reduces the scalp-electrode gap to reduce contact impedance. As a result, a long-term BCI application based on measurements of motion-onset visual evoked potentials (mVEPs) shows that the 3-hour BCI accuracy of the new electrode (77% to 100%) is approximately the same as that of conventional electrodes supported by a conductive gel during the first hour. Furthermore, the BCI system based on the new electrode can retain low contact impedance for 10 hours on scalp, which greatly improved the ability of BCI technique.
研究领域:
生物医学工程
·
神经科学
✓ 已验证
DOI
高影响因子
Journal of Tissue Engineering and Regenerative Medicine
·
2015
·Vol. 11
·期 5
·1562-1573
·
IF 5.199
Quan Liu,Yuchen Huang,Yong Lan,Qinhua Zuo,Chenghua Li,Yi Zhang,Rui Guo,Wei Xue
Two important issues in skin tissue engineering are the vascularization and regeneration of the dermis. Basic fibroblast growth factor (bFGF) is known to promote angiogenesis and accelerate wound healing. Direct delivery of bFGF to the wound area, however, would lead to a loss of bioactivity. To this end, bFGF-loaded alginate microspheres (Ms) were fabricated and incorporated into carboxymethyl chitosan (CMCS)–poly(vinyl alcohol) (PVA) to form a composite hydrogel. Scanning electron microscopy (SEM) results indicated that the incorporation of Ms does not significantly affect the inner structure of CMCS–PVA. In an in vitro study, the release of bFGF from Ms–CMCS–PVA in a sustained manner retained higher bioactivity over a 2-week period. Full-thickness burn wounds were created in the dorsal area of rats for in vivo evaluation of skin regeneration treated with CMCS–PVA hydrogel, with and without bFGF. Compared with the control, CMCS–PVA and bFGF–CMCS–PVA groups, the bFGF/Ms–CMCS–PVA group revealed significantly faster wound recovery rates, with re-epithelialization and regeneration of the dermis. Moreover, the bFGF/Ms–CMCS–PVA group had the highest density of newly formed and mature blood vessels during the 2 mweek treatment period. The ability of the bFGF/Ms–CMCS–PVA hydrogel to accelerate wound healing in a full-thickness burn model suggests its potential for use in dermal tissue regeneration. Copyright © 2015 John Wiley & Sons, Ltd.
研究领域:
生物材料学
·
组织工程学
·
医学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF NON-CRYSTALLINE SOLIDS
·
2019
·
IF 2.6
Bocai Lin,Hongxing Hu,Zhengwei Deng,Libin Pang,Haizhen Jiang,Deping Wang,Jiusheng Li,Zhongtang Liu,Hui Wang,Xiangqiong Zeng
The synthetic hydrogel owns huge potential and broad prospects in cartilage tissue engineering due to a series of unique properties, such as bioactivity, the nutrition ions release ability, high mechanical properties and chondrogenesis capacity. Bioactive glass (BG) and PVA have been widely investigated and reported with safety and excellent biocompatibility as tissue engineering materials. In this study, we have synthesized a novel composite hydrogel formed by crosslinking between bioactive glass and PVA for cartilage repair, furthermore, we have explored the reaction mechanism of this hydrogel. It was found that hydrogen bonding was formed by the hydroxyl groups in PVA combining with the oxygen atoms from the non-bridge Si-O bond in bioactive glass, which can explain better mechanical properties for PM group than that of PVA. The tensile and compressive stress of PM5 hydrogel group has reached 4.8 MPa and 1.8 MPa equaling mechanical properties of natural articular cartilage. Moreover, the hydrogel can significantly support the proliferation of mice chondrocytes in vitro. Meanwhile, it can also effectively upregulate the expression of chondrogenesis related genes (AGGRECAN, SOX9, COL2). Therefore, the novel hydrogel possesses excellent properties in cartilage repair, and exhibits potential medical applications in the future.
研究领域:
生物材料学
·
组织工程学
·
再生医学
✓ 已验证
产品关联
DOI
高影响因子
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
·
2024
·
IF 4.9
Dai Zhang,Xinxin Zhang,Daopeng Zou,Fengyi Zhang,Xijiang Chang,Xiaoyang Yue,Hao Li
BiOBr is a bismuth-containing photocatalytic material that exhibits visible light activity, making it highly promising for applications in photocatalytic degradation of pollutants and ecological protection. However, its application is hinder by the powder form and small particle size. Loading a powder photocatalyst on a suitable carrier is a common way to solve this challenge. This study proposes that PVA hydrogel can be used as a highly efficient carrier to enhance the photocatalytic degradation performance of BiOBr. By adding a foaming agent, the pore structure of hydrogel was improved and the degradation performance to pollutants in wastewater was increased. The impact of various factors, including BiOBr photocatalyst loading, solution pH, recycling stability, and reactive species, on the photocatalytic degradation process were investigated. The performance of the PVA/BiOBr composite hydrogel to degrade methylene blue (MB) under simulated solar irradiation was studied. After a 120 min photocatalytic reaction, PVA/BiOBr-1.0 % composite hydrogel removed 99 % of 10 mg·L −1 MB, which was superior to pure BiOBr photocatalyst. This investigation is of significance as it provides insights into the integration of BiOBr catalysts key role of the PVA hydrogel carriers in enhancing the catalytic performance of BiOBr photocatalyst in wastewater treatment .
研究领域:
环境科学
·
材料科学
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF HAZARDOUS MATERIALS
·
2021
·
IF 10.588
Zhike Wang,Ting-Ting Li,Hao-Kai Peng,Hai-Tao Ren,Ching-Wen Lou,Jia-Horng Lin
Hydrogels have extensively studied as adsorbents, raw materials for the preparation of adsorbent hydrogels have low strength, while high strength hydrogels have weak adsorption capacity. In this study, PVA hydrogel was crosslinked via trihydroxy melamine and epichlorohydrin, and β-cyclodextrin with strong adsorption capacity was added to remove the heavy metal ions . Results showed that the addition of trihydroxy melamine with 8%, the compressive strength of the hydrogel was increased by approximately 20%. The Langmuir isotherm model showed that the adsorption capacity of the hydrogel for Pb(II) and Ni(II) reached 505.9 mg/g and 286.7 mg/g, respectively, and the efficiency of removing the low-concentration heavy metal ions in water more than 99%. The hydrogel is low cost, and maintained highly removal efficiency under low pH. The removal efficiency of the hydrogel remained above 90% after five repeated adsorption-desorption experiments. The hydrogels have a potential to be used in wastewater treatment as adsorbents.
研究领域:
环境科学
·
材料科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2025
·
IF 13.2
Hongjian Zhang,Yi Fang,Wen Chen,Yong Zhang
Demanded by the increasing popularity of human–machine interface, wearable electronics, robots, etc., the current mainstream pressure sensing technologies could not fully fulfill the accurate and in-time sensing requirement. Ionic-based pressure sensors, which are inspired by the working mechanism of human haptic system, present several outstanding advantages and great potential. However, how to effectively control the ion transport and compensation under mechanical deformation in ionic-devices serves as a critical challenge in this new and under-developed field. In this study, we designed and constructed an ion-selective membrane based on 2D MXene to modulating the directional cations immigration in PVA hydrogels, which is the first demonstration in this field. To be specifically, the cations are trapped by the cation-selective MXene membrane due to the negative charge surface of MXene, which creating the ion concentration gradient within the PVA hydrogels and in turn the maximum power output up to 3.81 μW/cm 2 . On this basis, we prepare a concentration difference cell by placing the MXene film between two PVA hydrogels with different ionic concentration. Furthermore, the MXene film was placed between two PVA hydrogels with different moduli and the ion transport could be induced by the stress-induced inhomogeneous deformation, resulting in the formation of ionic concentration differential. Above two models were packed as the arrays to create an ionic touchpad, which is capable of detecting and differentiating various external stimuli accurately. This work explores two kinds of transport models by designing the layer arrangement of PVA hydrogels and MXene membrane, which provides a simple and versatile strategy for developing ionic-based self-powered pressure sensors.
研究领域:
材料科学
·
传感器技术
·
生物仿生学
✓ 已验证
产品关联
DOI
高影响因子
Gels
·
2024
·Vol. 10
·期 12
·788
·
IF 5
Xiaolei Guo,Hao Zhang,Manman Wu,Zhan Tian,Yanru Chen,Rui Bao,Jinghao Hao,Xiao Cheng,Chuanjian Zhou
Hydrogels, known for their outstanding water absorption, flexibility, and biocompatibility, have been widely utilized in various fields. Nevertheless, their application is still limited by their relatively low mechanical performance. This study has successfully developed a dual-network hydrogel with exceptional mechanical properties by embedding amino-functionalized polysiloxane (APSi) networks into a polyvinyl alcohol (PVA) matrix. This hydrogel effectively dissipates energy through dense sacrificial bonds between the networks, allowing for precise control over its tensile strength (ranging from 0.07 to 1.46 MPa) and toughness (from 0.06 to 2.17 MJ/m3) by adjusting the degree of crosslinking in the polysiloxane network. Additionally, the hydrogel exhibits excellent conductivity (10.97 S/cm) and strain sensitivity (GF = 1.43), indicating its potential for use in wearable strain sensors. Moreover, at the end of its life (EOL), the sensor waste can be repurposed as an adsorbent material for metal ions in water treatment, achieving the recycling of hydrogel materials and maximizing resource utilization.
研究领域:
材料科学
·
生物医学工程
·
环境科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF SOL-GEL SCIENCE AND TECHNOLOGY
·
2021
·Vol. 101
·期 1
·103-113
·
IF 2.326
Wang Chen,Shen Zhifeng,Hu Pengfei,Wang Tao,Zhang Xing,Liang Lidong,Bai Jianguang,Qiu Liewei,Lai Xiaojuan,Yang Xiaowu,Zhang Kang
Borax-PVA hydrogels with excellent mechanical properties are prepared by simple physical mixing of polyvinyl alcohol (PVA, thickener) and borax (cross-linking agent) at room temperature. The resulting hydrogel is a three-dimensional structure composed of boric ester bonds as physical crosslinking points. Thus, the spatial structure, swelling properties, viscoelastic properties, tensile properties, and self-healing properties of hydrogels with different ratios of borax and PVA are studied. XRD confirmed that the hydrogels have similar structures near 2 θ values of 10 and 20. The microstructure of the hydrogel is confirmed by SEM and TEM. With an increase of borax mass fraction, the pore structure and morphology of hydrogel are more ordered, with substantial quantities of water immobilized within their three-dimensional structure. The viscoelastic properties and tensile properties showed that when the mass fraction of borax is 5%, the storage modulus and compressive stress of the hydrogel are the highest, reaching 100 Pa and 5.6 kPa, respectively. In addition, through physical and chemical stimulation (heating and varying pH, respectively), the hydrogels also showed reversible gel–sol conversion characteristics, indicating that the boric ester bonds have self-healing properties.
研究领域:
材料科学
·
化学工程
✓ 已验证
产品关联
DOI
高影响因子
NEW JOURNAL OF CHEMISTRY
·
2023
·Vol. 47
·期 12
·5825-5831
·
IF 3.3
Cheng Zhou,Shengping Dai,Xiaoshuang Zhou,Hao Zhu,Guanggui Cheng,Jianning Ding
Inspired by the stimuli-responsive ability of biological, a variety of hydrogel have been prepared by stimulus, showing great application value in actuators, soft robots, etc. However, it is still challenging to prepare a toughness hydrogel by the way of stimuli-responsive. Herein, we constructed a novel dual-network structure PNIPAM/PVA hydrogel using reversible molecular configuration conversion of PNIPAM chains. Under the stimulus of ethanol, the elastic modulus of PNIPAM/PVA hydrogel can be increased by 47 times (5 times the change of the modulus of sea cucumbers’ tissue) and the stress can be six times of the original. The dynamic borate ester bond formed by the cross-linking of PVA and borax in the hydrogel enables rapid self-healing (η > 99%) within three minutes without external stimulus in the natural environment. In addition, PNIPAM/PVA hydrogels also showed outstanding underwater reversible thermokinetic properties (>25°) based on the hydrophilic/hydrophobic conversion of PNIPAM under thermal stimulation. The successful preparation of ethanol stimulus-enhancing self-healing PNIPAM/PVA hydrogel actuators, provides a new idea for the development of the soft underwater robots.
研究领域:
材料科学
·
生物仿生学
·
软体机器人
✓ 已验证
产品关联
DOI
高影响因子
ADVANCED FUNCTIONAL MATERIALS
·
2021
·Vol. 31
·期 25
·2101648
·
IF 18.808
Zhen Wang,Dongmei Fu,Dazhi Xie,Shaoming Fu,Juanyan Wu,Shuanghu Wang,Fei Wang,Yicheng Ye,Yingfeng Tu,Fei Peng
Micro/nanomotors are attracting booming research enthusiasm with their revolutionary potential in biomedicine, sensing, and nanoengineering. Among the motors proposed, magnetic micro/nanomotors are of great interest with their high controllability and field biocompatibility. Yet the fabrication of magnetic actuated especially helical motors requires expensive and complicated instruments, 3D printing or glancing angle deposition, etc. Here, a soft and biocompatible helical poly(vinyl alcohol) (PVA) hydrogel motor via a versatile set-up is engineered. The obtained helical hydrogel motor offers high capacity for chemokine CXCL12 and superparamagnetic iron oxide (Fe 3 O 4 ) nanoparticles, which can then allow magnetic manipulation. With a low strength rotating magnetic field, the system is able to perform 3D precision navigation, necessary to steer the robotic system to a model diseased area. The chemokine cues from the hydrogel motor, acting as the synthetic leader cell, then directs immune T cell chemotactic migration. In a previously reported cell manipulating motor system, towing or pushing a single/two cell was demonstrated, with limited efficiency. This motor platform represents a novel approach for directing endogenous cell chemotaxis and organizing immune response.
研究领域:
生物医学工程
·
免疫学
·
纳米技术
✓ 已验证
DOI
高影响因子
SEPARATION AND PURIFICATION TECHNOLOGY
·
2022
·
IF 9.136
Yuzhe Cao,Xunkai Zhu,Zejuan Ni,Bo Ge,Wei Li,Guina Ren,Xiao Miao,Xin Shao,Cancan Liu
Freshwater has become a rare resource on account of population increase and environmental pollution. At present, most the solar-driven interfacial evaporators used for water polluted by organic solvents and dyes have an outstanding nature of clean water production due to their special design. However, its downside is that contaminants remaining in the residual polluted water cannot be removed. Herein, a device applied to water polluted by organic solvents and dyes is formed by a hydrogel-based interfacial evaporator (PVA hydrogel/CNTs) and non-wetting fabric. The photodegradation efficiency of the non-wetting fabric is 95.7% for Rh B dye after five cycles. Meanwhile, the organic solvents including toluene, cyclohexane and so on are cleared through the non-wetting fabric. Importantly, the device presents a clean water production rate of 1.73 kg·m −2 ·h −1 under 1 sun illumination and it has a freshwater produce rate of 1.63 kg·m −2 ·h −1 after 6 h of desalination experiments. Furthermore, the device displays the performance of salt resistance in a 3 h NaCl dissolution experiment. A new strategy is provided for interfacial water evaporation technology used for water dyed by organic solvents and dyes purification and has a great application potential.
研究领域:
材料科学
·
环境科学
✓ 已验证
产品关联
DOI
高影响因子
LANGMUIR
·
2024
·
IF 3.7
Yumin Wang,Ting Xu,Lide Xu,Gan Miao,Fangchao Li,Xiao Miao,Jingwei Lu,Zhiqiang Hou,Guina Ren,Xiaotao Zhu
Adhesive hydrogels are considered to be promising interfacial adhesive materials for various applications; however, their adhesive strength is significantly reduced when immersed in liquid environments (water and oil) due to obstruction of the liquid layer or swelling in liquid, and they could not always be reused when the failure of the adhesive performance occurred. Herein, a graphite oxide/poly(vinyl alcohol) (GO/PVA) hydrogel with strong adhesion in air and under liquid environments was developed by rationally regulating the interactions of water and dimethyl sulfoxide (DMSO) in the binary liquid system. The strong interaction between water and DMSO allowed the water layer of the GO/PVA hydrogel on the hydrogel surface to act as a shield to repel oil in air, under water, and even when immersed in oil, and it also endowed the obtained hydrogel with antiswelling property when immersed in water and oil. Importantly, the GO/PVA hydrogel could serve as an advanced adhesive to firmly bond different substrates in air, under water, and under oil, and interestingly, its dry and wet adhesive performance was repeatable and recyclable. This work is expected to be an important addition to the field of adhesive soft materials.
研究领域:
材料科学
·
化学工程
·
粘合材料
✓ 已验证
产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）