INTERNATIONAL JOURNAL OF PHARMACEUTICS
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2022
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IF 6.51
Jinfeng He,Jing Wang,Shoubei Gao,Yanshuai Cui,Xianbing Ji,Xiaoyu Zhang,Longgang Wang
Photothermal therapy uses photothermal agents (PTAs) to convert light energy to heat energy under near-infrared light to kill local tumors in cancer patients or speed up wound healing in diabetic patients. However, it is difficult to achieve high photothermal conversion efficiency for most of PTAs. Herein, daptomycin (Dap) micelles-stabilized palladium nanoflowers (Dap-PdNFs) were prepared for the first time. The palladium nanoflowers (PdNFs) inside of the Dap-PdNFs were 106 nm. The temperature of the Dap-PdNFs solution quickly rose from 26.8 °C to 52.0 °C within 10 min under irradiation with high photothermal conversion efficiency up to 38%. In addition, the cell viability of HeLa cells and HT-29 cells of Dap-PdNFs exceeded 95% in the absence of near-infrared light, indicating that Dap-PdNFs had good biocompatibility. Meanwhile, the inhibition rate of Dap-PdNFs on HeLa cells was as high as 71.2% under irradiation of 808 nm near-infrared light. More importantly, Dap-PdNFs had a good healing effect on wounds of diabetic mice under irradiation of 808 nm near-infrared light. In short, this research provides a facile method for the application of Dap-PdNFs in safe and efficient tumor treatment and wound healing.
研究领域:
生物医学工程
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纳米医学
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肿瘤学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
ACS Sustainable Chemistry & Engineering
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2017
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IF 5.951
Ning Ma,Xuehua Liu,Ziqi Yang,Guojun Tai,Yanru Yin,Shuibo Liu,Hongliang Li,Peizhi Guo,X. S. Zhao
Palladium (Pd) nanoflowers with tunable thorns were prepared by a facile and rapid route with the assistance of carrageenan. The superior nature of well-dispersed Pd nanoflowers has been disclosed by X-ray diffraction, scanning electron microscopy, and transmission electron microscopy measurements. The growth of thorns of Pd nanostructures was first stimulated with the continuous introduction of l-ascorbic acid in the synthesis system and then reached a maximum length of about 132 nm, followed by a slight decrease in concentration. Electrochemical data showed that Pd nanoflowers with the longest thorns exhibited the highest catalytic current density of 1160 mA/mg, optimized tolerance to the poisoning, and the lowest onset potential while others showed a better cycle stability with a catalytic activity maintenance of above 96% after 300 cycles. It is suggested that the structure of thin thorns of Pd nanoflowers should be easier to damage than thick thorns during the electrocatalysis of ethanol. The relationship between Pd nanoflowers and properties as well as the key factors to form the nanoflower structure were discussed based on the experimental data.
研究领域:
材料科学
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电化学
✓ 已验证
产品关联
DOI
高影响因子
ELECTROCHEMISTRY COMMUNICATIONS
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2019
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IF 4.197
Zhongping Li,Yuxin Zhang,Ruiqi Zhu,Guangming Wen,Chuan Dong,Hung-Wing Li
Loading metal nanoparticles on the surface of nanosheet supports is an attractive approach to enhancing their catalytic performance. Herein, palladium nanoflowers (Pd NFs) were prepared on amino-functionalized fullerene (C 60 -NH 2 ) by hydrothermal self-assembly using ethylenediamine (EA). Reduction of Pd ions resulted in the formation of Pd nanoflowers with a fullerene bottom layer and Pd petals. Ethylenediamine, a functionalized fullerene precursor, afforded a nitrogen-rich fullerene that ensures strong interactions between Pd 2+ and functionalized fullerene and improves the chemical and morphological stability of the resulting Pd nanoflowers. Compared with spherical Pd nanoparticles supported on amino-functionalized fullerene (C 60 -NH 2 ), the Pd nanoflowers (Pd NFs/C 60 -NH 2 ) exhibit greatly superior activity towards the reduction of 4-nitrophenol (4-NP). The nanoflowers exhibit not only a remarkable UV–vis response for the conversion of 4-nitrophenol to 4-aminophenol (4-AP) (99% in 2.0 min) with a turnover frequency of 12.35 min −1 but also a high electrochemical sensitivity to 4-nitrophenol over a wide linear concentration range (5–1000 μM), providing a detection limit of 0.09 μM (S/N = 3) at room temperature. The excellent catalytic stability and durability of Pd NFs/C 60 -NH 2 offer promising applications in catalysis.
研究领域:
材料科学
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催化化学
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环境分析化学
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF POWER SOURCES
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2014
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IF 5.211
Jing-Jing Lv,Jie-Ning Zheng,Hong-Bao Zhang,Meng Lin,Ai-Jun Wang,Jian-Rong Chen,Jiu-Ju Feng
A simple and rapid one-pot wet-chemical method is developed for large-scale preparation of reduced graphene oxide nanosheets supporting Pt–Pd nanoflowers (Pt–Pd NFs/RGOs) using hydrazine hydrate as a reducing agent, without any seed, template, organic solvent , or special apparatus. The coexistence of sodium nitrite (NaNO 2 ) and poly(vinyl pyrrolidone) (PVP), and their amounts are essential for synthesis of flower-like nanostructures . Besides, Pt–Pd NFs/RGOs have higher catalytic activity and better durability for oxygen reduction reaction , compared with commercial Pt–C (50 wt %).
研究领域:
材料科学
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化学
✓ 已验证
产品关联
DOI
高影响因子
ELECTROCHIMICA ACTA
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2014
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IF 4.086
Jie-Ning Zheng,Li-Li He,Fang-Yi Chen,Ai-Jun Wang,Meng-Wei Xue,Jiu-Ju Feng
In this work, bimetallic alloyed platinum-palladium (PtPd) nanoflowers are fabricated by one-pot solvothermal co-reduction of Pt (II) acetylacetonate and Pd (II) acetylacetonate in oleylamine system. The as-prepared nanostructures show the enhanced electrocatalytic activity for oxygen reduction reaction (ORR), dominated by a four-electron pathway based on the Koutecky-Levich plots, mainly owing to the inhibition of the formation of Pt–OH ad via the downshift of d-band center for Pt. Meanwhile, PtPd nanoflowers display good methanol tolerance and improved stability for ORR. The chronoamperometry test reveals that the current of PtPd nanoflowers remains 45.9% of its original value within 6000 s, much higher than those of commercial Pt (36.7%) and Pd (32.2%) black catalysts. Therefore, PtPd nanoflowers with unique interconnected structures can be used as a promising cathode catalyst in direct methanol fuel cells.
研究领域:
材料科学
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化学工程
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能源科学
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）