JOURNAL OF HAZARDOUS MATERIALS
·
2013
·
IF 3.925
Ruijuan Qu,Xinghao Wang,Zhengtao Liu,Zhenguang Yan,Zunyao Wang
Cadmium (Cd) compounds are widely distributed toxic environmental and industrial pollutants, and they may bring danger to growth and development of aquatic organisms. The effects of Ca 2+ (as CaCl 2 ), Mg 2+ (as MgSO 4 ), K + (as KCl), pH and complexants (EDTA, the commercial DOM , and three homemade DOMs) on Cd toxicity to Photobacterium phosphoreum were evaluated in standardized 15 min acute toxicity tests . Increases in Ca 2+ concentration resulted in higher EC 50 values, indicating the competition between the two ions for uptake sites at the biotic ligand. Increased waterborne Mg 2+ also reduced Cd toxicity, but to a slightly lesser degree compared with Ca 2+ . The overall decline in EC 50 data with increasing K + in test solutions suggested that Cd toxicity was enhanced at larger K + concentration. The toxicity alleviation by H + was observed over the tested pH range of 5.0–9.0. Additions of complexing agents into the exposure water reduced Cd bioavailability via complexation of Cd 2+ , and complexants from different sources displayed different protective effect. The influence of these toxicity modifying factors was finally incorporated into a model that can predict acute cadmidum toxicity for Photobacterium phosphoreum . After validation with laboratory and natural waters, the developed model could support efforts to improve the ecological relevance of presently applied risk assessment procedures.
研究领域:
环境科学
·
毒理学
✓ 已验证
DOI
PubMed
高影响因子
FOOD CHEMISTRY
·
2019
·
IF 5.399
Yisheng Chen,Caihong Huang,Bernhard Hellmann,Zhengyu Jin,Xueming Xu,Guosheng Xiao
This study presented a HPTLC platformed luminescent biosensor system for screening captan residue. First, the potential bio-effects of layers materials on the detectability of a luminescent bacteria Photobacterium phosphoreum (ATCC 11040) as the sensor cell were assessed. From comparison, it was noteworthy that the combination of sensor cells with normal silica gel layer exclusively gave outstanding detectability (<10 ng/zone). On this basis, HPTLC mediated separation and biosensing was further optimized. Then, the obtained graphic results were digitally quantified via software processing, offering satisfactory selectivity, linearity ( R 2 = 0.9901 within 10–80 ng/zone) and sensitivity (0.5 mg/kg against MRLs ≥ 6 mg/kg). Additionally, the performance of the established method was validated with different fruits (recover rates 75–96%, RSD < 11.8%). Meanwhile, it was demonstrated that detectability of this hybrid system would be tuneable by altering the combination of bacteria strains and layer materials, which was meaningful to strengthen the usability of microbial biosensors.
研究领域:
分析化学
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环境科学
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食品科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
CLEAN-Soil Air Water
·
2015
·Vol. 44
·期 1
·72-77
·
IF 1.945
Qun He,Ruijuan Qu,Xinghao Wang,Zhongbo Wei,Ping Sun,Zunyao Wang
Although it has been widely known that arsenic poses great threat to organisms and arsenic species account for the toxic effect of the metalloid, relatively little attention has been given to the arsenic toxicity to different organisms at different pH values. Three kinds of aquatic organisms including Photobacterium phosphoreum , Daphnia magna , and Danio rerio were used to study the effects of pH on the toxicity of arsenic. Toxicity test results were analyzed by calculating EC 50 values and for arsenic species at five different pH values (5.0, 6.0, 7.0, 8.0, and 9.0). As a result, As(III) is more toxic to the tested organisms than As(V), and P. phosphoreum was more sensitive to the toxicity of arsenic than D. magna and D. rerio . The toxicity of As(III) species is different for different organisms: dihydrogen arsenite, H 2 AsO 3 – , is more toxic to P. phosphoreum and D. rerio than arsenous acid, H 3 AsO 3 , while H 3 AsO 3 is more toxic to D. magna . As for As(V), arsenate, HAsO 4 2− , is the most toxic to P. phosphoreum , whereas dihydrogen arsenate, H 2 AsO 4 – , may be responsible for the toxicity to D. magna and D. rerio . As(III) and As(V) are more toxic to P. phosphoreum in an alkaline environment, while for D. magna in an acidic environment and As(III) is more toxic to D. rerio in an alkaline environment and As(V) in an acidic environment.
研究领域:
环境生物学
·
毒理学
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF HAZARDOUS MATERIALS
·
2014
·
IF 4.331
Hao Jin,Chao Wang,Jiaqi Shi,Lei Chen
The individual IC 50 (the concentrations causing a 50% inhibition of bioluminescence after 15 min exposure) of cadmium ion (Cd) and nine chlorinated anilines to Photobacterium phosphoreum ( P. phosphoreum ) were determined. In order to evaluate the combined effects of the nine chlorinated anilines and Cd, the toxicities of chlorinated anilines combined with different concentrations of Cd were determined, respectively. The results showed that the number of chlorinated anilines manifesting synergy with Cd decreased with the increasing Cd concentration, and the number manifesting antagonism decreased firstly and then increased. The joint toxicity of mixtures at low Cd concentration was weaker than that of most binary mixtures when combined with Cd at medium and high concentrations as indicated by TU Total . QSAR analysis showed that the single toxicity of chlorinated anilines was related to the energy of the lowest unoccupied molecular orbital ( E LUMO ). When combined with different concentrations of Cd, the toxicity was related to the energy difference ( E HOMO − E LUMO ) with different coefficients. Van der Waals’ force or the complexation between chlorinated anilines and Cd had an impact on the toxicity of combined systems, which could account for QSAR models with different physico-chemical descriptors.
研究领域:
环境科学
·
毒理学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
·
2014
·
IF 2.482
Xinghao Wang,Ruijuan Qu,Zhongbo Wei,Xi Yang,Zunyao Wang
Mercury (Hg) compounds are widely distributed toxic environmental and industrial pollutants and they may bring danger to growth and development of aquatic organisms. The distribution of Hg species in the 3 percent NaCl solution was calculated using the chemical equilibrium model Visual MINTEQ, which demonstrated that Hg was mainly complexed by chlorides in the pH range 5.0–9.0 and the proportions of HgCl 4 2− , HgCl 3 − and HgCl 2 (aq) reached to 95 percent of total Hg. Then the effects of cations (Ca 2+ , Mg 2+ , K + and H + ), anions (HCO 3 − , NO 3 − , SO 4 2− and HPO 4 2− ) and complexing agents (ethylene diamine tetraacetic acid (EDTA) and dissolved organic matter (DOM)) on Hg toxicity to Photobacterium phosphoreum were evaluated in standardized 15 min acute toxicity tests . The significant increase of 6.3-fold in EC 50 data with increasing pH was observed over the tested pH range of 5.0–8.0, which suggested the possible competition between hydroxyl and the negatively charged chloro-complex. By contrast, it was found that major cations (Ca 2+ , Mg 2+ and K + ) have little effect on Hg toxicity to P. phosphoreum . An interesting finding was that the addition of HPO 4 2− significantly increased Hg toxicity, which may imply that the addition of phosphate increased the soluble Hg–chloro complex species. Additions of complexing agents (EDTA and DOM) into the exposure water increased Hg bioavailability via complexation of Hg. Finally, a model which incorporated the effect of pH, HPO 4 2− , HCO 3 − , SO 4 2− and DOM on Hg toxicity was developed to predict acute Hg toxicity for P. phosphoreum , which may be a useful tool in setting realistic water quality criteria for different types of water.
研究领域:
环境生物学
·
毒理学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
AQUATIC TOXICOLOGY
·
2014
·
IF 3.513
Dali Wang,Ya Gao,Zhifen Lin,Zhifeng Yao,Weixian Zhang
Metal oxide nanoparticles (NPs) have been used increasingly and are likely to accumulate in natural water bodies, where they encounter and interact with other environmental chemicals. These interactions result in joint effects on biological systems and the environment. However, compared with the intensive research examining the toxicities of individual NPs, the toxicities of NP mixtures remain relatively unexplored. In this work, we studied the joint effects of NPs and their most likely coexisting chemicals in the environment, including NPs with different compositions, humic substances, and surfactants. Our results indicate that the joint effects of NP mixtures were usually simple addition, which is commonly adopted in real risk assessment. However, the joint effects obtained for mixtures that contained ZnO were exclusively associated with antagonism. In addition, the mixtures of NPs and surfactants resulted in complex joint effects, i.e., antagonistic, additive, and synergistic effects were found for the mixtures with ZnO, NiO, and Fe-oxide, respectively. Our study suggests that the assessments of the ecological risk of NPs, particularly ZnO NPs, should consider the impact of their coexisting chemicals in the environment.
研究领域:
环境科学
·
毒理学
✓ 已验证
DOI
高影响因子
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
·
2013
·
IF 2.203
R.-J. Qu,X.-H. Wang,M.-B. Feng,Y. Li,H.-X. Liu,L.-S. Wang,Z.-Y. Wang
This study investigated the effect of pH on cadmium toxicity to three aquatic organisms: Photobacterium phosphoreum , Daphnia magna and Carassius auratus . The acute toxicity of Cd 2+ to P. phosphoreum and D. magna at five pH values (5.0, 6.0, 7.0, 8.0, and 9.0) was assessed by calculating EC 50 values. We determined that Cd 2+ was least toxic under acidic conditions, and D. magna was more sensitive to the toxicity of Cd than P. phosphoreum . To evaluate Cd 2+ -induced hepatic oxidative stress in C. auratus at three pH levels (5.0, 7.25, 9.0), the activity of antioxidant enzymes (superoxide dismutase, catalase and glutathione peroxidase), the level of glutathione and the malondialdehyde content in the liver were measured. Oxidative damage was observed after 7 d Cd exposure at pH 9.0. An important finding of the current research was that Cd 2+ was generally more toxic to the three test organisms in alkaline environments than in acidic environments.
研究领域:
环境科学
·
水生毒理学
·
生态毒理学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
·
2018
·Vol. 25
·期 10
·9636-9646
·
IF 2.8
Li Chenguang,Qu Ruijuan,Chen Jing,Zhang Shuo,Allam Ahmed A.,Ajarem Jamaan,Wang Zunyao
Triclosan (TCS) is an antibacterial and antifungal agent widely used in personal care products, and it has been frequently detected in the aquatic environment. In the present study, the acute toxicity of TCS to Daphnia magna , Photobacterium phosphoreum , Danio rerio , and Limnodrilus hoffmeisteri was assessed under different pH conditions. Generally, TCS was more toxic to the four aquatic organisms in acidic medium. The LC 50 values for D. magna and D. rerio were smaller among the selected species, suggesting that D. magna and D. rerio were more sensitive to TCS. In addition, the oxidative stress-inducing potential of TCS was evaluated in Carassius auratus at three pH values. Changes of superoxide dismutase (SOD) and catalase (CAT) activity, glutathione (GSH) level, and malondialdehyde (MDA) content were commonly observed in all TCS exposure groups, indicating the occurrence of oxidative stress in the liver of C. auratus . The integrated biomarker response (IBR) index revealed that a high concentration of TCS induced great oxidative stress in goldfish under acidic condition. This work supplements the presently available data on the toxicity data of TCS, which would provide some useful information for the environmental risk assessment of this compound.
研究领域:
环境科学
·
毒理学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）