MACROMOLECULAR BIOSCIENCE
·
2015
·Vol. 15
·期 6
·829-838
·
IF 3.851
Haiyang Yu,Zhaohui Tang,Dawei Zhang,Wantong Song,Taicheng Duan,Jingkai Gu,Xuesi Chen
A novel random copolypeptide of ornithine, arginine, glycine, and aspartic acid [Poly(ornithine-co-arginine-co-glycine-co-aspartic acid), Poly(O,R,G,D)] has been prepared through ring-opening polymerization of N -δ-carbobenzoxy-l-ornithine N -carboxyanhydride [Orn(Cbz)-NCA)], l-glycine N -carboxyanhydride (Gly-NCA) and β-benzyl l-aspartate N -carboxyanhydride [Asp(Bn)-NCA], following by subsequent deprotection and guanidization. The structure of Poly(O,R,G,D) was confirmed by nuclear magnetic resonance (NMR) spectroscopy and gel permeation chromatography (GPC). Low cytotoxicity of Poly(O,R,G,D) was confirmed from MTT assay. The Poly(O,R,G,D) contain some internal sequences of RXXR ( X = O, R, G, or D) that could be proteolytically cleaved to expose the cryptic CendR element and bind to Neuropilin-1. This would lead to vascular and tissue permeabilization. Therefore trypsin-cleaved Poly(O,R,G,D) increase the vascular leakage of Evans blue from dermal microvessels at the injection site in vivo skin permeability assay. The intratumoral injection of the Poly(O,R,G,D) significantly enhanced the concentration of cisplatin-loaded nanoparticles in MCF-7 solid tumors. These results show that Poly(O,R,G,D) could increase the vascular leakage and tissue penetration of nanoparticles in a solid tumor and can be used as a potential polymeric tumor-penetrating agent.
研究领域:
生物化学
·
肿瘤学
·
药剂学
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产品关联
DOI
PubMed
高影响因子
POLYMERS FOR ADVANCED TECHNOLOGIES
·
2014
·Vol. 25
·期 5
·575-580
·
IF 1.964
Aihua Ma,Tingwei Hu,Shaoyun Shan,Hongying Su,Shuisheng Wu,Qingming Jia
HNO 3 -doped poly(o-aminophenol) (PoAP) was synthesized by a facile chemical polymerization without using any surfactants or templates. Sphere-like microstructures of PoAP are obtained via self-assembling of two-dimensional nanoplates. The different microstructures of PoAP could be easily controlled by controlling polymerization conditions, and the possible formation mechanism of PoAP microstructures follows the prickly-fluffy-full sphere growth process. By susceptibility test, the as-synthesized PoAP exhibits superior and sustained antibacterial activities against the typical Gram-positive Bacillus subtilis . Transmission electron microscope, scanning electron microscopy, and antibacterial test showed that morphologies of the PoAP have an obvious influence on its antibacterial activities, and the reason was further discussed. The resultant PoAP in this study may have potential applications as biological materials. Copyright © 2014 John Wiley & Sons, Ltd.
研究领域:
材料科学
·
微生物学
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产品关联
DOI
高影响因子
International Journal of Electrochemical Science
·
2023
·Vol. 12
·期 4
·3417-3431
·
IF 1.5
Cheng Chen,Shihui Qiu,Songlv Qin,Guoping Yan,Haichao Zhao,Liping Wang
The free amine-containing poly(o-phenylenediamine) (PoPD) nanoparticles with significant dispersibility in organic solvents have been synthesized by chemical oxidative polymerization of o-phenylenediamine mono-hydrochloride salt. The epoxy coatings with different contents of PoPD nanoparticles (0.5 wt%, 1 wt% and 2 wt%) were then prepared by curing reaction of epoxy resin, amine hardener and amine containing PoPD nanoparticles. The corrosion protection properties of the as prepared coatings on Q235 steel were investigated by potentiodynamic polarization, open circuit potential (OCP) and electrochemical impedance spectroscopy (EIS) technique in 3.5 wt % NaCl aqueous solution for 90 days. The results indicate that the coatings with 0.5 wt% PoPD nanoparticles (0.5-PDEP) exhibits high anticorrosive performance, which is attributed to the improved barrier effect of the nano-fillers and redox catalytic capability of embedded PoPD nanoparticles with the evidence of scanning electron microscope (SEM) and XRD. This novel amine-containing PoPD nanoparticles give a promising way to enhance the anticorrosion performance of epoxy coatings and potentially have a wider range of applications in anticorrosion related engineering applications.
✓ 已验证
DOI
高影响因子
Journal of Macromolecular Science Part A-Pure and Applied Chemistry
·
2013
·
IF 0.807
Tingxi Li,Chengqian Yuan,Yuhua Zhao,Quanliang Chen,Meng Wei,Yanmin Wang
Poly(o-phenylenediamine) (PoPD) submicrospheres with an average diameter of about 400 nm have been successfully synthesized in glycine solution by simply mixing o-phenylenediamine (oPD) and ammonium persulfate at room temperature. The macromolecular structure, crystallinity and thermal stability of the as-prepared product were characterized by Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD) and thermogravimetric analysis (TGA). Results showed that the doped PoPD is partly crystal and exhibits good thermal stability. The formation mechanism of the PoPD submicrospheres was investigated by monitoring the morphology development with the polymerization time, indicating that growth of the submicrospheres is a self-assembly process. This method is facile and applicable for the large scale fabrication of PoPD submicrospheres.
研究领域:
材料科学
·
高分子化学
·
纳米材料
·
有机合成
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DOI
高影响因子
Desalination and Water Treatment
·
2024
·
IF 1
Xuyin Lin,Jinwen Jiang,Jun Wang,Jiaofen Lin,Aikebaier Reheman
ABSTRACT In this study, we used mesoporous silica materials as inorganic carrier and poly(o-phenylenediamine) with more active amino and imino groups as organic ligand to obtain functionalized adsorbent. The composite adsorbent poly(o-phenylenediamine) modified mesoporous composites (MPP) were prepared by loading poly(o-phenylenediamine) onto the surface of the aminated mesoporous material through in-situ polymerization. It was found that the maximum saturation adsorption capacity of MPP reached 225 mg/g when the solution pH, temperature, initial Hg(II) concentration, and adsorption time were 4, 298.15 K, 100 mg/L, and 240 min, respectively. When common interfering ions Zn(II), Ni(II), Cu(II), Ca(II), Mg(II) and Al(III) were present, the adsorption of Hg(II) by MPP still showed good selectivity. The adsorption of Hg(II) by MPP followed quasi-secondary kinetics and the Langmuir adsorption isotherm model, indicating that the adsorption process was chemisorption. In addition, MPP removed up to 81.35% of Hg(II) from industrial wastewater. After five cycles for adsorbent regeneration experiments, the adsorption capacity of MPP could reach 191.67 mg/g, indicating that the adsorbent has good regeneration performance and potential application value for removal of Hg(II).
研究领域:
环境科学
·
材料科学
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DOI
高影响因子
KOREAN JOURNAL OF CHEMICAL ENGINEERING
·
2014
·Vol. 31
·期 12
·2192-2197
·
IF 1.241
Anjum Muhammad Naveed,Zia Khalid Mahmood,Zhu Lihua,Haroon-ur-Rashid,Ahmad Mirza Nadeem,Zuber Mohammad,Tang Heqing
Self-assembled hollow microspheres poly( o -chloroaniline) (POC) have been synthesized by simple oxidative polymerization of o -chloroaniline using camphor-sulfonic acid (CSA) as dopant acid and ammonium persulfate (APS) as oxidant. The POC microspheres were characterized by means of FTIR, XRD and SEM analysis. Adsorption characteristics of POC spheres were studied by using methyl orange (MO) as adsorbate. It was found that adsorption of MO by POC was better described by pseudo-second-order kinetics than any other kinetic model, such as the pseudo-first-order and intra-particle diffusion models. Langmuir adsorption isotherm model was the best to fit experimental data. The results showed that hollow microspheres of POC can be used as novel and low-cost adsorbent for removal of organic dye from waste water.
研究领域:
材料科学
·
环境科学
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DOI
高影响因子
International Journal of Electrochemical Science
·
2023
·
IF 1.5
Chaogang Zhou,Chaojin Zhou,Jiawei Zhang
The poly(o-phenylenediamine)-ZnO (PoPD-ZnO) composite were synthesized by in-situ polymerization, and the waterborne polyurethane was used as the binder. The corrosion inhibition performance of the PoPD-ZnO composite coating on stainless steel was investigated. The structures of homopolymer PoPD and PoPD-ZnO composite were characterized by Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD) and scanning electron microscopy (SEM). Cyclic voltammetry demonstrates the redox properties and stability of the composite. After soaking in 3.5% NaCl for a certain period of time, the corrosion resistance of the polymer coating was studied by potentiodynamic polarization and electrochemical impedance spectroscopy (EIS). The results show that the homopolymer PoPD coating and the PoPD-ZnO composite coating can protect the stainless steel. The corrosion rate of the PoPD-ZnO composite coating with good corrosion resistance is 1.9% of bare steel. In addition, the addition of nano-ZnO facilitates the formation of a compact and low-defect coating, thereby impeding the erosion of corrosive media and improving the corrosion resistance of PoPD coatings.
研究领域:
材料科学
·
电化学
·
防腐蚀工程
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产品关联
DOI
高影响因子
CORROSION SCIENCE
·
2019
·
IF 6.355
Mingjun Cui,Siming Ren,Jibin Pu,Yonggang Wang,Haichao Zhao,Liping Wang
In this research, soluble poly(o-phenylenediamine) nanoparticles were synthesized to noncovalently functionalize the graphene nanosheets via π-π interactions, and the corresponding protective performance of epoxy composite coatings was also investigated. Results showed that the impedance modulus of the composite coatings incorporated with 0.5–1.0% G-Popd was about 10 10 Ω cm 2 after 60 days of immersion. Furthermore, the corrosion of substrate was still retarded even if there is an artificial scratch to the composite coatings. The superior protective performance of the composite coating derived from the synergistic action in the barrier property of graphene nanosheets and metal surface passivation by Popd nanoparticles.
研究领域:
材料科学
·
腐蚀与防护
·
纳米技术
✓ 已验证
DOI
高影响因子
Materials Research Express
·
2019
·Vol. 6
·期 9
·095601
·
IF 1.449
Hao Xu,Xiang-Hui Yan,Ziwei Meng,Tong Xue,Dong Li,Guoli Fang,Hongfang Shen
Nitrogen-doped mesoporous carbon/poly-o-phenylenediamine composites (denoted as N-MC/PoPD) were successfully synthesized by sacrificial hard template method followed by in situ oxidation polymerization initiated by FeCl3. It is revealed that the resultant N-MC/PoPD composites still remained original graphitization structure and narrow pore size distributions (centered at ∼3.8 nm) but suffered visibly monotonical decrease in specific surface area after oPD was increasingly polymerized onto N-MC with an increase of the mass ratio of PoPD to N-MC from 1:1 to 5:1. As supercapacitor electrode measured by galvanostatic charge-discharge in 6 mol L−1 KOH, a volcano curve was found when plotting specific capacitance of the N-MC/PoPD versus the mass ratio of N-MC to oPD; the N-MC/PoPD(2:1) with moderate surface area and the highest electrochemical conductivity delivered the highest specific capacitance of 229 F g−1 at a current density of 1 A g−1, which is twice of that obtained on the single N-MC with the maximum surface area. The remarkable enhancement in specific capacitance could be ascribed to the synergistic effect between two components of N-MC and PoPD.
研究领域:
材料科学
·
电化学
·
纳米技术
·
能源存储
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产品关联
DOI
高影响因子
ANALYTICAL BIOCHEMISTRY
·
2024
·
IF 2.6
Jieming Dong,Hongyu Zhang,Zhixiang Ding,Junyao Li,Laidi Xu,Yong Kong,Guojun Zheng
A molecularly imprinted electrochemical sensor was facilely fabricated for the detection of thymol (THY). o -Phenylenediamine (oPD) was used as the functional monomer and electropolymerized on the surface of the glassy carbon electrode (GCE) by using THY as the templates. After the THY templates were removed with 50 % (v/v) ethanol, imprinted cavities complementary to the templates were formed within the poly( o -phenylenediamine) (PoPD) films. The resultant molecularly imprinted PoPD/GCE (MI-PoPD/GCE) was used for the detection of THY, and a wide linear range from 0.5 to 100 μM with a low limit of detection (LOD) of 0.084 μM were obtained under the optimal conditions. The developed MI-PoPD/GCE also displays high selectivity , reproducibility and stability for THY detection. Finally, the content of THY in the real samples was accurately determined by the as-fabricated MI-PoPD/GCE, demonstrating its high practicability and reliability.
研究领域:
分析化学
·
生物医学工程
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产品关联
DOI
PubMed
高影响因子
SYNTHETIC METALS
·
2014
·
IF 2.222
Fang Liao,Siwei Yang,Xiubing Li,Lijun Yang,Zhihui Xie,Chenshu Hu,Shuai Yan,Tongyan Ren,Zhiduo Liu
Tunable fluorescent nanomaterials are of great significance. In this paper, the poly(o-phenylenediamine) (PoPD) nanospheres were synthesized via chemical oxidation polymerization of o-phenylenediamine (oPD) monomers by (NH 4 ) 2 S 2 O 8 (APS) at room temperature. It is interesting that when this fluorescent nanosphere was doped by F, S and Se via a simple hydrothermal progress, the fluorescence spectrum remarkably changed. The emission peak of F-doped and S-doped PoPD nanosphere was at 411 nm and 530 nm, the spectrum blue shift can be attributed to the electron-withdrawing effect of F and S. On the other side, the emission peak of Se-doped PoPD nanospheres were at 594 nm and can be attributed to the electronic donor effect of Se. These nanomaterials can be used as ultra-sensitive fluorescent detection system (ppb level) for Cu 2+ , Ca 2+ , Hg 2+ and H 2 O 2 . The tunable spectrum and sensing performance of this system is interesting and significant.
研究领域:
材料科学
·
纳米技术
·
分析化学
·
荧光光谱
✓ 已验证
DOI
高影响因子
SYNTHETIC METALS
·
2024
·
IF 4
Jieming Dong,Junyao Li,Laidi Xu,Hongyu Zhang,Yong Kong,Guojun Zheng
Au nanoparticles (AuNPs)-poly(o-phenylenediamine) (PoPD) nanocomposite was facilely prepared by a one-step method and used as the built-in redox probe for the decoration of a glassy carbon electrode (GCE). As the template molecules, diethylstilbestrol (DES) was immobilized on the AuNPs-PoPD/GCE surface by using electropolymerized o -phenylenediamine (oPD) as the imprinting layer, which was then eluted from the imprinting layer with the mixture of ethanol and water (v/v, 50 %). The resultant molecularly imprinted PoPD/AuNPs-PoPD/GCE (MI-PoPD/AuNPs-PoPD/GCE) was used for the electrochemical detection of DES in a wide range from 0.1 to 10 μM, and the limit of detection (LOD) was 0.062 μM (S/N = 3). The parameters for DES detection were also optimized in this work. The molecularly imprinted DES sensor showed high stability, selectivity and reproducibility, and it was successfully used for the detection of DES in the milk samples.
研究领域:
分析化学
·
生物医学工程
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）