Journal of Materials Chemistry A
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2023
·Vol. 11
·期 29
·15833-15843
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IF 11.9
Yi Tao,Zikun Tang,Yihong Zhong,Dequan Bao,Zhenqiu Gao,Wei Zhao,Zhen Wen,Hao Zhang,Kanghong Wang,Xuhui Sun
Photoelectrochemical (PEC) water splitting is a promising approach for the conversion of solar energy to hydrogen fuel. However, the solar-to-hydrogen (STH) efficiency is still restricted by the kinetically sluggish oxidation reaction on the surface of the photoanode. Herein, a unique composite structure (ZnO@NiO–QDs) was developed as the photoanode, in which the highly dispersed ZnO (d-ZnO) particles derived from the pyrolysis of ZIF-8 serve as the scaffolds to support NiO (cocatalysts) and colloidal CdSe(CdSexS1−x)4(CdS)2 QDs (denoted as CAS, a light absorber). Due to the enhanced hole consumption accelerated by NiO cocatalysts, the optimized photoanode (d-ZnO@NiO0.03–CAS) exhibits a higher saturated current density (Jsc) of 21.7 mA cm−2 than the d-ZnO–CAS photoanode (15.6 mA cm−2) under standard one sun (AM 1.5 G, 100 mW cm−2) solar irradiation. More importantly, such an electrode can still work as an electrocatalyst under light-off conditions via a sole electrochemical (EC) process. Thus, a well-designed bifunctional electrode that integrates cocatalysts and light absorbers makes it possible to generate hydrogen efficiently under both light-on and light-off conditions, providing an efficient and low-cost paradigm to improve the hydrogen evolution performance.
研究领域:
材料科学
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能源转换与储存
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纳米技术
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DOI
高影响因子
FOOD HYDROCOLLOIDS
·
2023
·
IF 10.7
Mengjun Wang,Linyu Nian,Jiaoyang Wu,Shujie Cheng,Zhiping Yang,Chongjiang Cao
The deterioration of postharvest fruits and vegetables caused by ethylene and microorganisms leads to global resource waste. Therefore, the development of multifunctional packaging materials that scavenge ethylene and inhibit microorganisms is essential to extend the shelf life of fruits and vegetables and minimize waste. Herein, the excellent photocatalytic performance of [email protected] nanoparticles (NPs) was incorporated into chitosan (CS) and sodium alginate (SA) matrix by layer-by-layer (LBL) assembly method to obtain CS/SA/ [email protected] nanocomposite films. These as-prepared films exhibited excellent antibacterial (antibacterial ratio >99%) and ethylene scavenging properties (scavenging ratio >40%) due to the synergistic effect between visible light-induced reactive oxygen species (ROS) and the higher specific surface area of ZIF-8. The extended shelf life of kiwifruit further confirmed the enhanced preservation performance of CS/SA/ [email protected] nanocomposite films. In addition, with the addition of [email protected] NPs, the color, and transparency of the films decreased, but the mechanical strength, thermal stability, hydrophobicity, and barrier properties were improved. In summary, the successful construction of ethylene scavenging and antibacterial films provides new ideas for the innovation of environmentally adaptive and functionalization of films.
研究领域:
材料科学
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食品科学
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纳米技术
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农业工程
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DOI
高影响因子
JOURNAL OF FLUORESCENCE
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2023
·
IF 2.7
Xu Zichen,Xu Hedan,Duan Hongliang,Li Junjie,Hu Xiao,Jiang Kaixin,Wang Guixue,Zhang Yuanyuan
Simple and sensitive detection of cardiac biomarkers is of great significance for early diagnosis and prevention of acute myocardial infarction (AMI). Here, a ratiometric fluorescent nanohybrids probe (AuNCs-QDs) was synthesized through the coupling of bovine serum albumin-functionalized gold nanoclusters (AuNCs) with CdSe/ZnS quantum dots (QDs) to realize simple and sensitive detection of cardiac biomarker myoglobin (Mb). The AuNCs-QDs probe shows pink fluorescence under UV light, with two emission peaks at 468 nm and 630 nm belonging to QDs and AuNCs, respectively. Importantly, the presence of Mb caused fluorescence quenching of the blue-emitting QDs, thereby inhibiting the fluorescence resonance energy transfer (FRET) process between QDs and AuNCs, and reducing the fluorescence intensity ratio (F 468 /F 630 ) of AuNCs-QDs probe effectively. As the concentration of Mb increases, the ratiometric fluorescent probe also exhibits a visible fluorescence color change. The detection limit was as low as 4.99 μg/mL, and the response of the probe to Mb showed a good linear relationship up to 0.52 mg/mL. Moreover, the probe has excellent specificity for Mb. Besides, the AuNCs-QDs has been applied to detect Mb of urine samples. More importantly, we also developed an AuNCs-QDs probe modified smartphone-aided paper-based strip for on-site monitoring of Mb. As far as we know, this is the first report of a smartphone-aided paper-based strip for on-site quick monitoring of Mb, which provides a useful approach for AMI biomarker monitoring and may can be extended to other medical diagnostics.
研究领域:
生物传感器
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纳米技术
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医学诊断
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心脏病学
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DOI
PubMed
高影响因子
ChemNanoMat
·
2023
·Vol. 9
·期 4
·e202200532
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IF 3.8
Xinbing Jiang,Lu Qiao,Huan Yang,Ben Q Li,Shujiang Ding
Graphical SiO 2 @Au@SiO 2 @QDs nanocomposite with dual-functionality of simultaneous heating and temperature sensing were prepared. The heating is activated by a NIR laser through SPR effect while thermal sensing is accomplished by QDs PL thermometry. These nanocomposites are used as a drug carrier for in vitro chemotherapy-photothermal co-treatment for malignant cells. This paper reports the synthesis of multi-layer SiO 2 @Au@SiO 2 @QDs nanoparticles with a dual-functionality of simultaneous heating and temperature sensing and their applications to in vitro chemo-thermal therapy. The heating is activated by a NIR-light through resonance excitation of surface plasma while in-situ thermal sensing is accomplished by the QDs photoluminescent (PL) effect. These dual function nanoparticles are used as a drug carrier for in vitro chemotherapy-photothermal co-treatment for malignant cells. A comparative study of drug release profiles was performed with and without 808 nm laser irradiation. The drug release rate was accelerated by a rise of temperature, which is induced by plasmonic heat generation associated with Au nanoshells; while the temperature change is monitored by the QD nanoparticles at the same time. The results showed that SiO 2 @Au@SiO 2 @QDs-DOX platform enabled the combination of local specific chemotherapy with external near-infrared (NIR) photothermal therapy and significantly improved the efficacy of cancer treatment. This combined treatment demonstrated synergistic chemotherapeutic-thermal effects compared to chemotherapy or photothermal therapy alone, resulting in higher efficacy.
研究领域:
纳米技术
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癌症治疗
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材料科学
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生物医学工程
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DOI
高影响因子
MICROCHIMICA ACTA
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2021
·Vol. 188
·期 12
·1-9
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IF 5.833
Tang Zhuoyun,Wei Zeliang,Huang Ke,Wei Yinhao,Li Dongdong,Yan Shixin,Huang Jin,Geng Jia,Tao Chuanmin,Chen Piaopiao,Ying Binwu
Human immunodeficiency virus (HIV) infection inflicts significant economic and social burdens on many countries worldwide. Given the substantial morbidity and mortality from HIV infection, there is an urgent need for accurate and early detection of the virus. In this study, immunofluorescence and visual techniques are described that detect the HIV-1 p24 antigen, which relied on selective recognition of Ag + /Ag nanoparticles (Ag NPs) and Cu 2+ /Cu + using cadmium telluride quantum dots (CdTe QDs). After the sandwich immunoreactions were accomplished, the alkaline phosphatase (ALP) hydrolyzed L-ascorbic acid 2-phosphate (AAP) to form ascorbic acid (AA) that further reduces Ag + and Cu 2+ to Ag NPs and Cu + , respectively. This method was highly sensitive and selective and could detect as low as 1 pg/mL of p24 antigen by naked eyes and had a good linearity in the concentration range 1–100 pg/mL. When using Ag + and Cu 2+ as media, the limit of detection (LOD) of the new method was 0.3 pg/mL and 0.2 pg/mL, respectively. Compared with clinical electrochemiluminescence immunoassay (ECLIA) results and clinical data, this method demonstrated good consistency for the quantification of HIV-1 p24 antigen in 34 clinical serum samples. In addition, this method could accurately distinguish HIV from other viruses and infections such as hepatitis B virus , systemic lupus erythematosus , hepatitis C virus , Epstein-Barr virus , cytomegalovirus , lipemia , and hemolysis . Therefore, our dual-mode analysis method may provide additional solutions to identify clinical HIV infection. Graphical abstract An immunofluorescence and visualization dual-mode strategy for the detection of p24 antigen was constructed based on immune recognition reaction and a phenomenon that cadmium telluride quantum dots (CdTe QDs) can selectively recognize Ag + /Ag nanoparticles (Ag NPs) and Cu 2+ /Cu + .
研究领域:
病毒学
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免疫学
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医学诊断
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DOI
PubMed
高影响因子
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
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2019
·Vol. 411
·期 18
·4025-4030
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IF 3.286
Li Hao-Wen,Hua Xin,Long Yi-Tao
Time-of-flight secondary ion mass spectrometry (ToF-SIMS) has shown promising applications in single-cell analysis owing to its high spatial resolution molecular imaging capability. One of the main drawbacks hindering progress in this field is the relatively low ionization efficiency for biological systems. The complex chemical micro-environment in single cells typically causes severe matrix effects, leading to significant signal suppression of biomolecules. In this work, we investigated the signal enhancement effect of graphene quantum dots (GE QDs) in ToF-SIMS analysis. A × 160 magnification of ToF-SIMS signal for amiodarone casted on glass slide was observed by adding amino-functionalized GE QDs (amino-GE QDs), which was significantly higher than adding previously reported signal enhancement materials and hydroxyl group-functionalized GE QDs (hydroxyl-GE QDs). A possible mechanism for GE QD-induced signal enhancement was proposed. Further, effects of amino-GE QDs and hydroxyl-GE QDs on amiodarone-treated breast cancer cells were compared. A significant signal improvement for lipids and amiodarone was achieved using both types of GE QDs, especially for amino-GE QDs. In addition, ToF-SIMS chemical mapping of single cells with better quality was obtained after signal enhancement. Our strategy for effective ToF-SIMS signal enhancement holds great potential for further investigation of drug metabolism pathways and the interactions between the cell and micro-environment.
研究领域:
分析化学
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生物医学工程
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材料科学
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细胞生物学
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药学
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DOI
PubMed
高影响因子
TALANTA
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2017
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IF 4.162
Sifang Lv,Feng Chen,Chunyan Chen,Xiaoming Chen,Hang Gong,Changqun Cai
We report a rapid and facile resonance light scattering (RLS) technique that utilizes CdTe quantum dots (CdTe QDs) probe to detect microRNA-122. The RLS sensor is ingeniously designed with P1 and P2 , two cDNA sequence probes with partially complementary sequences to miRNA-122. The amine-modified P1 and P2 are coupled to the surface of QDs to form functional QDs-P1 and QDs-P2 conjugates, which are collectively referred to as QDs-P. The cDNAs hybridize with the target miRNA to rapidly induce the self-assembly of QDs probe and change RLS intensity. The proposed technique can detect miRNA-122 within 40 min. RLS intensity is enhanced in proportion with miRNA-122 concentrations of 0.16–4.80 nM and has a low detection limit of 9.4 pM. In addition, the assay satisfactorily detects miRNAs in human serum samples. Thus, the assay has considerable potential for the analysis of other interesting tumor makers.
研究领域:
生物化学
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分子生物学
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分析化学
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PubMed
高影响因子
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
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2014
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IF 2.354
Yonghai Song,Mei Huang,Dan Luo,Dandan Zhong,Haoqing Hou,Fugang Xu
In this study, we investigated the interaction between EcoRI and CdS QDs modified with different functional groups as well as the conformational changes of EcoRI in the process. MUD capped (CdS–OH QDs) and UDT capped (CdS–CH 3 QDs) CdS QDs were separately prepared and used to react with EcoRI, respectively. The interaction was characterized by various spectroscopic techniques including UV–vis absorption, fluorescence and Fourier transform infrared (FTIR) spectroscopy, together with electrophoresis methods. The strength of interaction for EcoRI with CdS–OH QDs and CdS–CH 3 QDs was evaluated and analysed. Relevant thermodynamic parameters such as Δ H , Δ G and Δ S were calculated and a static quenching interaction process was proposed. The conformational change of EcoRI interacted with CdS–OH QDs or CdS–CH 3 QDs was also measured and compared. Finally agarose electrophoresis assay was performed and revealed that the enzyme activity of EcoRI was somewhat conserved after interaction with CdS QDs. This study contributed to a better understanding of protein-NPs interaction and created a framework for applications of nanomaterial-biomolecule conjugation in some fields such as nanobiology and nanomedicine.
研究领域:
纳米生物技术
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生物化学
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分子生物学
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纳米医学
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DOI
高影响因子
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
·
2022
·Vol. 414
·期 6
·2065-2078
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IF 4.478
Ou Panpan,Wu Jiawen,Lin Yu,Tan Xuecai,Wu Yeyu,Chen Zhifan,Wei Fucun,Huang Kejing
Chloramphenicol (CAP) is widely used in the food industry and animal husbandry due to its effective antibiotic effect active against gram-positive and gram-negative microorganisms. However, research shows that it can cause serious adverse reactions and side effects in the human body. In order to effectively monitor the residues of CAP, a novel and simple photoelectrochemical (PEC) sensor for sensitive detection of CAP is fabricated based on M-TiO 2 -CdTe QDs/CdS QDs composite. The results show that the prepared M-TiO 2 not only retains the original morphology and structure of MIL-125(Ti), but also exhibits more abundant pore structure and good photoelectrochemical properties. Compared with M-TiO 2 , the as-prepared M-TiO 2 -CdTe QDs/CdS QDs composite exhibits excellent PEC performances including about ninefold enhancement of photocurrent intensity, which is ascribed to the large surface of M-TiO 2 and the introduction of CdTe QDs and CdS QDs. Based on the selective inhibitory effect of CAP in the photocurrent intensity of the M-TiO 2 -CdTe QDs/CdS QDs PEC system, a novel PEC sensor for CAP concentration determination is constructed. The designed PEC sensor demonstrates a linear range from 1 to 140 nmol L −1 with a detection limit of 0.14 nmol L −1 (S/N = 3). Moreover, the method is applied to real milk samples to quantify the CAP residues with spiked recoveries in the range of 96.3–106%, and the possible detection mechanism of the M-TiO 2 -CdTe QDs/CdS QDs PEC system is also discussed. Graphical abstract
研究领域:
分析化学
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材料科学
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环境科学
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食品科学
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DOI
PubMed
高影响因子
FOOD CHEMISTRY
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2021
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IF 7.514
Rong-Rong Zhang,Xin-Tian Gan,Jin-Jin Xu,Qiao-Fen Pan,Hua Liu,Ai-Li Sun,Xi-Zhi Shi,Ze-Ming Zhang
A highly effective molecularly imprinted electrochemiluminescence sensor was constructed for prometryn determination in environmental and biological samples by using perovskite quantum dots coated with a molecularly imprinted silica layer (MIP/CsPbBr 3 -QDs) as the recognition and response element. MIP/CsPbBr 3 -QDs were immobilized on a glassy carbon electrode (GCE) through electropolymerization, and the electrochemiluminescence (ECL) response of MIP/CsPbBr 3 -QDs could be motivated under the condition of H 2 O 2 as co-reactant. ECL signal was selectively quenched with prometryn by hindering electron transfer and directly proportional to the logarithm of prometryn concentration (0.10–500.0 μg/L) with a correlation coefficient of 0.9960. Limits of detection in fish and seawater samples were 0.010 μg/kg and 0.050 μg/L, respectively. Excellent recoveries of 88.0%–106.0% were acquired for fish and seawater samples with a relative standard deviation below 4.2%. The constructed MIECL sensor based on MIP/CsPbBr 3 -QDs showed good stability, accuracy, and precision for sensitive detection of prometryn in aquaculture products and environmental samples.
研究领域:
环境科学
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分析化学
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DOI
PubMed
高影响因子
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
·
2023
·Vol. 24
·期 11
·9325
·
IF 5.6
Meng Ji,Liwei Ren,Chunyuan Tian,Xuming Zhuang,Feng Luan
In this paper, glutathione (GSH)-coated Zn-doped CdTe quantum dots (QDs) with different particle sizes were synthesized using the “reflow method”, and the interaction mechanism between the two QDs and lactoferrin (LF) was investigated systemically with different spectroscopic methods. The steady-state fluorescence spectra showed that the LF formed a tight complex with the two QDs through static bursting and that the electrostatic force was the main driving force between the two LF–QDs systems. The complex generation process was found to be spontaneous (ΔG < 0) and accompanied by exothermic and increasing degrees of freedom (ΔH < 0, ΔS > 0) by using the temperature-dependent fluorescence spectroscopy. The critical transfer distance (R0) and donor–acceptor distance (r) of the two LF–QDs systems were obtained based on the fluorescence resonance energy transfer theory. In addition, it was observed that the QDs changed the secondary and tertiary structures of LF, leading to an increase in the hydrophobicity of LF. Further, the nano-effect of orange QDs on LF is much larger than that of green QDs. The above results provide a basis for metal-doped QDs with LF in safe nano-bio applications.Keywords:quantum dots (QDs);lactoferrin (LF);interaction;spectroscopic methods;thermodynamic constants;nano-effects
研究领域:
生物化学
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纳米生物学
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PubMed
高影响因子
JOURNAL OF SOLID STATE CHEMISTRY
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2022
·
IF 3.656
Meng Chen,Chao Wang,Lei Wang,Jixiang Xu
In this work, carbon quantum dots@In 2 S 3 hollow tube (CQDs@In 2 S 3 ) with sheet-like hierarchical structure was synthesized by sulfidation CQDs@In-MIL-68. The CQDs@In 2 S 3 -2 exhibited the optimal Cr(VI) reductive ratio of nearly 100% after 45 min light irradiation in solution with pH of 4. The enhanced Cr(VI) reduction activity was ascribed to the efficient separation of electrons and holes after coupling of CQDs. The ·O 2 − was the dominant active specie to reduce Cr(VI), and possible mechanism was proposed. This work provides thought for design of high-performance photocatalysts by loading electron-collecting species to remove environmental pollutants .
研究领域:
环境科学
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材料科学
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产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）