FOOD CHEMISTRY
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2024
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IF 8.5
Yumei Chen,Jialin Zhang,RuiRui Liu,Ying Zhang,Jingming Zhou,Hongliang Liu,Yankai Liu,Ke Yan,Yanhua Qi,Enping Liu,Xifang Zhu,Aiping Wang
A label-free electrochemical immunosensor was developed to rapidly detect tilmicosin (TMC) residues in pork and milk. The immunosensor was constructed by immobilizing a high-affinity monoclonal antibody against TMC on an rGO-PEI-Ag nanocomposite-modified electrode. The rGO-PEI-Ag nanocomposites were prepared by mixing polyethyleneimine (PEI) modified reduced graphene oxide (rGO) with AgNO 3 solution. The prepared rGO-PEI-Ag nanocomposites showed good redox activity and conductivity, as characterized by ultraviolet-visible spectroscopy (UV–Vis), transmission electron microscopy (TEM), and X-ray diffraction (XRD). During the preparation process, staphylococcal protein A (SPA) was added to targetedly bind the Fc segment of the monoclonal antibody. The immunosensor showed a low detection limit (LOD) of 0.0013 ng/mL, a linear range of 0.01–100 ng/mL, and recoveries ranging from 92.77 to 100.02% in pork and 92.26–101.23% in milk. Furthermore, the immunosensor exhibited good stability, reproducibility, and specificity in detecting TMC in pork and milk real samples.
研究领域:
分析化学
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食品科学
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纳米技术
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生物化学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
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2022
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IF 5.518
Hao Tong,Hang Chen,Yali Zhao,Miaomiao Liu,Yi Cheng,Jie Lu,Yehan Tao,Jian Du,Haisong Wang
Ideal adsorption material with large adsorption capacity, strong mechanical strength and satisfied reusability plays crucial role in efficient industrial wastewater treatment and oil-water separation. Herein, porous reduced graphene oxide/poly(ethyleneimine)/polydimethylsiloxane (rGO/PEI/PDMS) sponge with robust structure was proposed under mild conditions. Owing to the enhanced interfacial interaction between rGO and PDMS when employing PEI as adhesion layer, the rGO layer was tightly stacked onto the surface of porous channels within PDMS skeleton. Compared to the pristine PDMS sponge, the water contact angle, maximum adsorption capacity towards chloroform and compressive strength at 60% strain of the champion rGO/PEI/PDMS sponge were effectively increased from 101°, 7.38 g/g and 35.82 kPa to 135°, 16.38 g/g and 111.78 kPa, respectively. The porous rGO/PEI/PDMS sponge also demonstrated good adsorption capacities towards various substrates, including organic solvents (carbon tetrachloride, chloroform, dichloromethane , dimethylformamide , n-hexane, petroleum ether, and toluene) and oils (pump oil, silicone oil soybean oil). The rGO/PEI/PDMS sponge was further assessed as oil/water separation material, displaying high efficiency and good selectivity to the representatives of both heavy and light oils. More importantly, the resultant sponge delivered excellent recyclability without obvious attenuation of adsorption capacity at least 60 cycles. This work proposed a perspective for rational designing and fabricating efficient adsorbent with robust structure and durability in practical application.
研究领域:
材料科学
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环境工程
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化学工程
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION
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2022
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IF 3.682
Juan Wu,Xi Wang,Binglong Zhu,Qinting He,Yaheng Zhang,Wei Jiang
As one of the well-known anticancer drugs, methotrexate (MTX) has been limited in clinical application due to its side effects on normal tissues. This study focused on the one-step hydrothermal synthesis and in vitro evaluation of Fe3O4/RGO-PEI as MTX carriers for targeted anticancer therapy. In which, the Fe3O4 provided magnetic response properties; RGO acted as a stage for Fe3O4 loading and improved the dispersion of Fe3O4; polyethylenimine (PEI) was used as a surface modifier and a storehouse for MTX. The prepared Fe3O4/RGO-PEI nanocomposites exhibited a suitable size, good stability and magnetic responsibility. And the MTX loading content and loading efficiency were calculated to be 26.6% and 90.5%, respectively. What’s more, due to the diffusion and dissolution of PEI, the Fe3O4/RGO-PEI-MTX exhibited excellent pH-sensitivity, the values of MTX release rate (%) within 48 h at pH 5.8 and 4.0 were 64.3% and 87.4%, respectively. Furthermore, MTT assays in cancer cells (HepG2) and normal cells (HUVEC) demonstrated that Fe3O4/RGO-PEI-MTX exhibited high anticancer activity while low toxicity to normal cells, and also the Fe3O4/RGO-PEI composites were practically non-toxic. Thus, our results revealed that Fe3O4/RGO-PEI-MTX would be a competitive candidate for targeted delivery and controlled release of MTX.
研究领域:
材料科学
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纳米技术
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药学
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癌症研究
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Nano Energy
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2020
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IF 16.602
Haitao Li,Charlynn Sher Lin Koh,Yih Hong Lee,Yihe Zhang,Gia Chuong Phan-Quang,Chao Zhu,Zheng Liu,Zhensheng Chen,Howard Yi Fan Sim,Chee Leng Lay,Qi An,Xing Yi Ling
Harvesting solar energy via pyroelectric technology is highly desired because it is a sustainable and clean solution to yield electricity. However, the low power output (below 5mW/m 2 ) and bulky device design of traditional devices hinder their practical applicability. Herein, we demonstrate a highly efficient sunlight-triggered pyroelectric nanogenerator (S-PENG) design that achieves unprecedented performance of 21.3 mW/m 2 under one sun irradiation. This is achieved via enhancing both the solar harvesting properties and the pyroelectric efficiencies rationally by employing polyethyleneimine (PEI) chemically modified reduced graphene oxide (rGO-PEI), and a pyroelectric layer based on a polarized polyvinylidene fluoride (PVDF) film respectively. Moreover, we demonstrate its practical application by adapting the S-PENG into a wearable outdoor bracelet. Using a facile hand-waving motion to replace the traditional bulky sunlight-alternating device, our compact bracelet can charge a fitness tracker after only 1 h of outdoor exposure, demonstrating its capability to be seamlessly integrated with outdoor sports activities. We expect our rational design to promote the development of S-PENG and pave the way for the utilization of sunlight as a viable on-the-go electrical source.
研究领域:
材料科学
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能源技术
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纳米技术
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF MEMBRANE SCIENCE
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2023
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IF 9.5
Qing Zeng,Chongshan Yin,Xi Li,Chunqing He
The wide distribution of the lateral size of lab-prepared graphene oxide (GO) sheets often complicates the measurement of accurate average size. Herein, a series of reduced-GO/polyethyleneimine (RGO/PEI) composite membranes with compact brick-wall structures were successfully prepared. The large lateral size of RGO sheets in the membrane benefited gas barrier properties, including oxygen, nitrogen, and water vapor. The RGO sheets acted as impermeable inorganic filler to prolong the diffusion path, forcing gas molecules to wiggle through the permeable and tortuous channels of the PEI/water mixture. The water vapor transmission rate of RGO/PEI composite membranes was relatively high, and a linear correlation was established between the length of PEI/water channels and the water vapor barrier property. The length of PEI/water channels under the same membrane thickness was determined by the lateral size of RGO sheets. Therefore, the statistic averages of lateral size of RGO sheets (from 2 . 48 μ m to 44 . 35 μ m ) showed a linear correlation with the water vapor barrier property, as confirmed by the positron annihilation technique and molecular dynamics simulations. In sum, the linear correlation could be used to practicably measure the statistic averages of lateral size of GO sheets according to water vapor permeability measurements.
研究领域:
材料科学
·
化学工程
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）