MATERIALS LETTERS
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2017
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IF 2.572
Shuo Wang,Ruixin Ma,Chengyan Wang,Shina Li,Hua Wang
Quaternary chalcogenide Cu2FeSnS4 (CFTS) thin film, a potential material for application as absorber layer in thin film solar cells (TFSCs), dye-sensitized solar cell and photocatalytic, are successfully synthesized by using a convenient blade-coating method. Alkali element Rb was incorporated into CFTS thin films in order to further improve the structure and surface morphology. X-ray diffraction, Raman spectroscopy and field emission scanning electron microscopy were used to characterize the phase purity, morphology and composition of CFTS particles and thin films. It showed that the diffusion of Rb ions is uniform in the films after sulfurization, Rb ions incorporation in CFTS thin films could improve the grain size and surface morphology. All the thin films became smooth and closely packed surface, the thickness of the incorporated films is around 1 μm.
研究领域:
材料科学
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光伏技术
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薄膜制备
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DOI
高影响因子
Biomed Research International
·
2019
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IF 2.197
Mengmeng Zheng,Wenxiu Zheng,Wei Wang,Hong Guo,Hui Cao,Xiaowei Cui,Shanshan Wang,Chunchao Han
Objective. The blood of cancer patients is in a state of hypercoagulability, easily leading to thrombosis. Anemia is also a complication of tumors. Anemia and thrombosis affect the treatment of tumor patients. Methods. Ginsenosides Rb were extracted from the stems and leaves of American ginseng using water-saturated ethanol and ethyl acetate in silica gel column. Tumor mice model was established by injecting H22 hepatocellular carcinoma cells into the axilla of mice. Mice were randomly divided into 6 groups: normal control group, model control group, positive control group, low dose group (7 mg/kg), middle dose group (14 mg/kg), and high dose group (35 mg/kg). After 18 days, the blood was obtained by picking the eyeball of mice. The levels of red blood cells (RBC), hemoglobin (HGB), neutrophils/lymphocytes radio (NLR), platelets (PLT), platelet distribution width (PDW), fibrinogen (FIB), and D-Dimer (D-D) were measured and compared in each group of mice. Results. The content of obtained ginsenosides Rb reached 90.05%. This extraction process was simple and reliable. Middle dose of ginsenosides Rb could significantly increase RBC and HGB levels (P<0.05). Moreover, ginsenosides Rb could significantly reduce NLR, PLT, PDW, FIB, and D-D (P<0.01). Conclusion. ginsenosides Rb could significantly improve anaemia and hypercoagulation of blood in cancer mice. Ginsenosides Rb are a potential anticoagulant and antianemia drug in treating cancer.
研究领域:
药理学
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肿瘤学
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血液学
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DOI
PubMed
高影响因子
JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY
·
2024
·
IF 5.9
Jian Yang,Daoming Chen,Meifang Cao,Xueqing Qiu,Xinping Ouyang
The catalytic dehydration of bio-derived lactic acid into acrylic acid is one of the research hotspots in the field of green chemical industry, but the selectivity of acrylic acid and the stability of catalyst still face great challenges. In this work, a modified Hβ zeolite catalyst was prepared by sequential nitric acid treatment and Rb ion-exchange for the gas phase dehydration of lactic acid to prepare acrylic acid. The nitric acid treatment increased the content of Lewis acid sites together with the decrease of the content of Bronsted acid sites, which enhanced the dehydration and hindered the decarboxylation/decarbonylation of lactic acid. Consequently, the selectivity of acrylic acid was improved. The Rb ion-exchange not only significantly decreased the density of acidic sites but also regulated the density of basic sites of the catalyst. The optimal 0.1NA-6.8Rb/Hβ catalyst treated by 0.1 mol/L of nitric acid and 6.8 wt% of Rb ion-exchange contributed to a 99.28 % conversion of lactic acid and 76.72 % yield of acrylic acid. The catalyst showed a better stability and was easy to regenerate, maintaining 87.35 % conversion of lactic acid and 62.49 % yield of acrylic acid, respectively, after two cycles of consecutive 48 h reaction.
研究领域:
绿色化学
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催化化学
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DOI
高影响因子
JOURNAL OF THE EUROPEAN CERAMIC SOCIETY
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2019
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IF 4.029
Huiling Zhang,Rongrong Yuan,Mengfeifei Jin,Zelong Zhang,Yanxia Yu,Weidong Xiang,Xiaojuan Liang
All-inorganic lead halide quantum dots (QDs) have attracted immense interest because of their excellent photoelectric properties. By virtue of a similar ionic radius and the same valence state, Rb + /Cs + mixed-cation have become a novel mechanism to adjust multi-color emission. However, their poor stability remains a serious problem that has not been solved satisfactorily. Interestingly, QDs glass shows good thermostability and moisture susceptibility. Herein, CsPbBr 3 : x Rb ( x = 0, 0.4, 0.6, 0.8) QD glasses which yield tunable emission spectra (475–523 nm) were synthesized successfully via glass crystallization. Most importantly, the as-prepared QDs glasses exhibited ultrastability under various atmospheric, water and heat conditions. Thus, synthesis of a mixed-cation perovskite QDs glass is a new method to achieve stable multi-color emission. They are also expected to become a new generation of photoelectric materials and can be prospectively applied to light-emitting devices.
研究领域:
材料科学
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光电技术
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纳米技术
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产品关联
DOI
高影响因子
JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY
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2021
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IF 3.849
Jianjun Guo,Xiaoliang Wang,Wenrong Wang,Lingling Jia,Wei Guo,Guohua Wu
Background Phoxim is a widely used organophosphorus pesticide in agriculture. People are paying more and more attention to its toxicity. At present, there is no appropriate way to solve the phoxim poisoning of silkworm , which severely affected the development of sericulture . Fe 2+ , Cu 2+ , Rb + exerted their biological effects through various forms in vivo . Methods To evaluate the effect of Fe 2+ /Cu 2+ /Rb + on phoxim poisoning in silkworm, Bombyx mori were treated with fresh mulberry leaves soaked in 2.5 mg/L phoxim for 2 min with 50 mg/L FeCl 2 , 150 mg/L CuCl 2 , or 0.5 mg/L RbCl from 5 days of the fifth-instar silkworm. Results Fe 2+ , Cu 2+ , and Rb + pretreatments significantly inhibited the phoxim-induced reduction of survival rate and alleviated the phoxim-induced poisoning symptoms. The protective effects of Fe 2+ , Cu 2+ , and Rb + on phoxim poisoning might be due to their enhancement of superoxide dismutase (SOD), catalase (CAT), and carboxylesterase (CarE) in the hemolymph and fat body of silkworm. This enhancement might reduce reactive oxygen species (ROS) accumulation and oxidative stress (OS) caused by phoxim poisoning. Thereby it reduced the damage to silkworm tissues and cells. Conclusions These results showed that Fe 2+ , Cu 2+ , and Rb + treatments protected the silkworm from phoxim poisoning by directly enhancing the activity of SOD, CAT, and CarE enzymes and reducing oxidative stress, but not dependent on the high expression of CYP genes. The use of Fe 2+ , Cu 2+ , and Rb + to enhance the activity of SOD, CAT, and CarE enzymes may be an underlying effective way to solve phoxim poisoning in the silkworm industry.
研究领域:
昆虫学
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毒理学
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农业
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DOI
PubMed
高影响因子
Journal of Materials Chemistry B
·
2022
·Vol. 10
·期 22
·4274-4284
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IF 7.571
Changchun Wen,Xiaolu Guo,Cunji Gao,Zhongkai Zhu,Nianqi Meng,Xing-Can Shen,Hong Liang
Specific tumor-responsive capabilities and efficient synergistic therapeutic performance are the keys to effective tumor treatment. Herein, AuNRs@SiO2–RB@MnO2 was developed as a new type of tumor-responsive nanotheranostic for multimodal imaging and synergistic chemodynamic/photothermal therapy. In AuNRs@SiO2–RB@MnO2, the SiO2 layer wraps the AuNRs, providing light absorption in the second near-infrared (NIR-II) region. The SiO2 layer also adsorbs the MnO2 nanosheets, which have Fenton-like activity, resulting in a fluorescent sensing platform based on the fluorescence quenching properties of MnO2 for rhodamine B dye. The fluorescence can be recovered by the consumption of MnO2 by glutathione, which simultaneously produces Mn2+ in the tumor region. The recovery of fluorescence reflects the consumption of glutathione and the increase in Mn2+, which produces hydroxyl radicals via Fenton-like reaction in the tumor microenvironment to realize chemodynamic therapy. Meanwhile, the AuNRs are a good photothermal reagent that can effectively absorb NIR-II light and convert it into heat energy to kill tumor cells via photothermal therapy. The NIR-II absorption performance of the AuNRs provides good photoacoustic imaging and deep photothermal performance, which is favorable for efficient NIR-II photoacoustic imaging-guided photothermal therapy. As a result, the AuNRs@SiO2–RB@MnO2 nanotheranostic exhibits outstanding imaging and synergistic chemodynamic/photothermal therapeutic performance for tumor imaging and treatment.
研究领域:
生物医学工程
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纳米医学
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肿瘤学
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DOI
高影响因子
JOURNAL OF ANALYTICAL ATOMIC SPECTROMETRY
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2020
·Vol. 35
·期 5
·953-960
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IF 3.498
Wen-Gang Liu,Shuang Wei,Jian Zhang,Cong Ao,Fu-Tian Liu,Bin Cai,Hong-Ying Zhou,Ji-Long Yang,Chao-Feng Li
A cation-exchange resin is commonly used to separate Sr from geological and environmental samples. AG50 resin is the most traditional cation-exchange resin and has the advantages of good reusability and low cost. Although AG50 resin can meet the demands of most conventional geological samples, eliminating 87Rb isobaric interference from samples with high Rb/Sr ratios (>30) is difficult during one-step separation. Separating Sr twice using AG50 resin is the general approach to Rb removal. The two-step separation method is time consuming and leads to a low Sr yield. This study aimed to improve the sample throughput and overcome the problem of 87Rb isobaric interference from imperfect separation. A new separation method involving hydrofluoric acid (HF acid) coprecipitation combined with a cation-exchange resin (i.e. AG50 resin) for samples with high Rb/Sr ratios was developed. HF acid was used as a coprecipitator to remove most Rb (>90%) and recover Sr before performing AG50 column chemistry. The reliability of this method was examined using the rhyolite standard JR-2, a typical sample with a high Rb/Sr ratio (Rb/Sr = 37.36). Results in the JR-2 case showed that approximately 92% of Rb and most of the matrix elements (K, Ti, Fe, Al, Mn and Na) could be removed effectively. Moreover, Sr recovery exceeded 91% during HF acid coprecipitation. After the removal of Rb by HF acid coprecipitation, the Sr fraction with high purity was easily obtained through one-step separation using the AG50 resin column. However, we found that the removal rates of Rb and some matrix elements (such as Al and Na) were strongly affected by the composition of Al–Ca–Mg in samples. Our separation method is more suitable for samples with high Rb/Sr ratios and low Ca and Mg contents. A series of silicate rock reference materials were selected to evaluate the applicability of our method, and the Sr isotopic results were consistent with previously reported values. Overall, this rapid, simple and low-cost method shows great potential for the separation of Sr from geological samples with high Rb/Sr ratios, such as alkaline feldspar granite, alkaline granite and alkaline rhyolite.
研究领域:
地质学
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地球化学
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DOI
高影响因子
TOXICOLOGY
·
2023
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IF 4.5
Miao Zhang,Xiaowen Bi,Shuai Liu,Yu Liu,Qiyu Wang
Sodium p -perfluorous nonenoxybenzene sulfonate (OBS), an economical alternative to perfluorooctane sulfonate (PFOS) in multiple industrial fields, is widely detected in the environment. The toxicity of OBS has received increasing attention. Pituitary cells are components of the endocrine system and act as vital regulators of homeostatic endocrine balance. However, the effects of OBS on pituitary cells remain unknown. The present study explores the effects of OBS (0.5, 5, and 50 μM) on GH3 rat pituitary cells after treatment for 24, 48, and 72 h. We found that OBS significantly inhibited cell proliferation in GH3 cells with remarkable senescent phenotypes, including enhanced SA-β-gal activity and expression of senescence-associated secretory phenotype (SASP)-related genes, cell cycle arrest, and upregulation of the senescence-related proteins γ-H2A.X and Bcl-2. OBS caused significant cell cycle arrest of GH3 cells at the G1-phase and concomitantly downregulated the expression of some key proteins for the G1/S transition, including cyclin D1 and cyclin E1. Consistently, the phosphorylation of retinoblastoma (RB), which plays a central role in regulating the cell cycle, was prominently reduced after OBS exposure. Furthermore, OBS notably activated the p53-p21 signalling pathway in GH3 cells, as evidenced by increased p53 and p21 expressions, enhanced p53 phosphorylation, and augmented p53 nuclear import. To our knowledge, this study is the first to reveal that OBS triggers senescence in pituitary cells via the p53-p21-RB signalling pathway. Our study demonstrates a novel toxic effect of OBS in vitro, and provides new perspectives for understanding the potential toxicity of OBS.
研究领域:
毒理学
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细胞生物学
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内分泌学
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产品关联
DOI
PubMed
高影响因子
CATALYSIS LETTERS
·
2023
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IF 2.8
Gao Youxin,Zhou Aojia,Min Jie,Yu Chengbing
A simple redox method was used to synthesize δ-MnO 2 and introduce the first main group metal elements between the layers of δ-MnO 2 . Through testing, we found that δ-MnO 2 doped with Rb + demonstrated the best catalytic performance for formaldehyde removal. Under the condition of 36 °C and the initial formaldehyde concentration of 200 ppm, a 200 mg of Rb-MnO 2 could achieve the percentage of removal of formaldehyde 97.48%. We found that doping elements with low electronegativity and large ion radius could weaken the Mn–O bond, which is conducive to the formation of reactive oxygen species and improve the performance of catalytic oxidation. Graphical Abstract
研究领域:
材料科学
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环境科学
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产品关联
DOI
高影响因子
MOLECULAR REPRODUCTION AND DEVELOPMENT
·
2015
·Vol. 82
·期 4
·305-314
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IF 2.527
Wei-Rong Yang,Yong Wang,Yi Wang,Jiao-Jiao Zhang,Jia-Hua Zhang,Cheng Lu,Xian-Zhong Wang
SUMMARY Mammalian target of rapamycin (mTOR) is known to be involved in mammalian cell proliferation, while S-phase kinase-associated protein 2 (SKP2) plays a vital role in the cell cycle. Within the testis, estrogen also plays an important role in Sertoli cell proliferation, although it is not clear how. The present study asked if mTOR is involved in 17β-estradiol-dependent Sertoli cell proliferation. We specifically assessed if extracellular signal-regulated kinase 1/2 (ERK1/2) and/or phosphoinositide 3-kinase/protein kinase B (PI3K/AKT) exert convergent effects toward the activation of mTOR signaling, and if this signaling regulates the expression of SKP2 through retinoblastoma (RB) and early mitotic inhibitor 1 (EMI1) protein and on CCNE1 and CCND1 mRNA levels. Treatment with 17β-estradiol for 15–90 min activated mTOR, with mTOR phosphorylation peaking after 30 min. U0126 (5 μM), a specific inhibitor of (MEK1/2), and 10-DEBC (2 μM), a selective inhibitor of AKT, both significantly reduced 17β-estradiol-induced phosphorylation of mTOR. Rapamycin suppressed 17β-estradiol-induced Sertoli cell proliferation, appearing to act by reducing the abundance of SKP2 , CCND1 , and CCNE1 mRNA as well as RB and EMI1 protein. These data indicated that 17β-estradiol enhances Sertoli cell proliferation via mTOR activation, which involves both ERK1/2 and PI3K/AKT signaling. Activated mTOR subsequently increases SKP2 mRNA and protein expression by enhancing the expression of CCND1 and CCNE1 , and inhibits SKP2 protein degradation by increasing EMI1 abundance. Mol. Reprod. Dev. 82: 305–314, 2015. © 2015 Wiley Periodicals, Inc .
研究领域:
生殖生物学
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细胞信号传导
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内分泌学
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产品关联
DOI
PubMed
高影响因子
Journal of Materials Chemistry C
·
2017
·Vol. 5
·期 47
·12422-12429
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IF 5.256
T. T. Deng,E. H. Song,Y. Y. Zhou,L. Y. Wang,Q. Y. Zhang
Three isotypic double perovskites A2BAlF6:Mn4+ (A = Rb, Cs; B = K, Rb) were synthesized via a facile co-precipitation method at room temperature. XRD Rietveld refinements and Raman spectra indicate that the neighboring smaller A-site or larger B-site cation in A2BAlF6:Mn4+ lowers structural stability, but suppresses the [AlF6] octahedron to increase the crystal field strength and bond strength of the Al–F bond. Cs2KAlF6:Mn4+ presents a sharp line red light and excellent moisture resistance, but experiences severe thermal quenching. In comparison, altering the A- or B-site cation to Rb, Rb2KAlF6:Mn4+ and Cs2RbAlF6:Mn4+ shows blue shifts in emission and declining water resistance, but enhancements in thermal stability. A combination of static and dynamic emission degradations demonstrates that the water resistance of Mn4+ emission mainly relies on the structural stability of the host matrix; meanwhile, the thermal stability highly depends on the rigidity of its local accommodation. The variations of the temperature-dependent white light-emitting diode (WLED) performances further evidence their sufficient thermal stability for LED applications. These findings suggest that neighboring-cation modulation might be a feasible guideline for exploiting stable Mn4+-activated fluoride red phosphors in warm WLED applications.
研究领域:
材料科学
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光学
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DOI
高影响因子
CHINESE JOURNAL OF STRUCTURAL CHEMISTRY
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2022
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IF 0.847
Qing Yao,Kaiyu Wang,Jie Zhang,Changqian Li,Chenyu Shang,Feitong Chen,Qi Huang,Qiqi Zhao,Weiwei Zhang,Xiaoyuan Zhan,Jianxu Ding
ABSTRACT Introducing inorganic cation into hybrid organic-inorganic perovskites (HOIPs) has attracted great attention because of the enhancement stabilities without sacrificing their excellent optoelectronic properties. Here, we introduce Cs and Rb into MAPbI 1.8 Br 1.2 single crystals (SCs) to dig out the mixed cation effect on optoelectronic performances and phase stabilities. Both Rb and Cs can increase the lattice capacity, which is sufficient to relieve the lattice stress caused by photon energy, thus achieving the purpose of stabilizing the lattice structure and inhibiting migration of halide ions, compared with MAPbI 1.8 Br 1.2 SC. On the other hand, the smaller polarity of Rb and Cs reduces the electron-phonon coupling, thus significantly inhibiting the migration of halide ions. Meanwhile, through planar photo-detectors, MA 0.9 Cs 0.1 PbI 1.8 Br 1.2 -based device behaves much excellent optoelectronic performance (R = 0.170 A/W, EQE = 51.39 %, D* = 4.42 × 10 12 Jones, on/off ratio: ~522).
研究领域:
材料科学
·
光学
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）