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RhB@Zn-MOF
Journal of Environmental Chemical Engineering · 2024 · IF 7.4

Highly sensitive and selective L-lactate monitoring in complex matrices with a ratiometric fluorescent sensor RhB@Zn-MOF

Bo Jing,Xinke Xu,Jingze Wang,Changyan Sun,Wenjun Li,Zhidong Chang

L-lactate is an essential biomarker in clinical diagnostics and food quality assessment. This study introduces a novel ratiometric fluorescence sensor, RhB@Zn-MOF, which was specifically designed for the sensitive and selective detection of L-lactate. Through the strategic incorporation of Rhodamine B (RhB) into Zn-MOF, RhB@Zn-MOF was synthesized, exhibiting dual-emission properties and could effectively distinguish L-lactate in complex biological and food matrices such as milk and sweat based on the competitive absorption mechanism. Notably, the sensor achieves a low detection limit of 0.091 μM and demonstrates excellent stability and reproducibility in varied conditions. Furthermore, the integration of the sensor with smartphone technology enables rapid, real-time analysis, showcasing potential applications in sports medicine, clinical environments, and the food industry.

研究领域: 分析化学 · 生物技术 · 临床诊断 · 食品科学 · 材料科学
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