Food Bioscience
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2025
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IF 5.9
Chunying Li,Jiahui Gong,Mengfei Tian,Hongying Ge,Xiaofei Xie,Qi Liang,Ying Yang,Chunjian Zhao,Ying Liu
The typical phytochemical emodin (ED) found in Rumex acetosa L. is extensively utilized in traditional medicine and demonstrates substantial pharmacological effects. However, Rumex acetosa L. is frequently regarded as a weed and discarded, leading to the underutilization of this valuable resource. In this work, a polydopamine molecularly imprinted resin (PDA@MIR) was successfully synthesized for the selective recognition and isolation of ED. The PDA@MIR is fabricated using macroporous resin X-5 as the carrier, dopamine as the green functional monomer, and emodin as the template molecule. The PDA@MIR displays excellent adsorption capacity (41.55 mg⋅g −1 ) for ED and adsorption affinity (IF = 3.19). Meanwhile, even after going through 10 cycles of adsorption-desorption tests, it demonstrates consistent adsorption efficacy and reusability. Moreover, the PDA@MIR can serve as the innovative column filler in solid-phase extraction (SPE) for applying to the separation of ED from Rumex acetosa L. roots extracts. The adsorption recovery rate of ED reaches 90.95%, while the effective adsorption recovery rate is 85.33%. The DFT simulation and NMR analysis reveales that the recognition mechanism of PDA@MIR is attributed to interactions involving hydrogen bonds and Van der Waals forces. Furthermore, this study provides valuable insights into the design of molecularly imprinted resin materials, which possess superior recognition capabilities and exceptional selectivity for the specific separation and recognition of phytochemicals from plant extracts.
研究领域:
药用植物学
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材料科学
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分析化学
✓ 已验证
产品关联
DOI
高影响因子
ACS Sustainable Chemistry & Engineering
·
2024
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IF 7.1
Jiahui Gong,Mengfei Tian,Ying Liu,Yuting Zhang,Junhui Xing,Qi Liang,Xiaofei Xie,Chunying Li,Chunjian Zhao
In this work, a dual-responsive ionic liquid (DR-IL), namely, [C4mim][FeCl4] was developed for simultaneously extracting and separating hydrophilic phytochemicals, including epicatechin (EC), dihydroquercetin (DQ), ferulic acid (FA), and hydrophobic phytochemicals, such as emodin (ED), chrysophanol (CP), and physcion (PC), from roots of wild Rumex acetosa L. The [C4mim][FeCl4] demonstrates considerable potential for extracting and separating target phytochemicals through temperature adjustment and accelerated phase separation facilitated by a neodymium magnet. Meanwhile, a high recovery yield is obtained by adding a magnetic field. The overall extraction yield of target phytochemicals achieved by [C4mim][FeCl4] reaches 16.12 mg/g under the optimal extraction conditions, representing a 1.53–2.39-fold increase compared to conventional solvents. Furthermore, the molecular simulation and FT-IR analysis reveal that the synergistic effect of van der Waals forces and hydrogen bonds significantly contributed to the higher extraction yields of target phytochemicals.
研究领域:
植物化学
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分析化学
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药用植物研究
✓ 已验证
产品关联
DOI
高影响因子
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2025
·
IF 8.5
Jiahui Gong,Mengfei Tian,Mengying Zhang,Xiaolong Yang,Yujiao Song,Hongying Ge,Wenxue Sun,Chunying Li,Chunjian Zhao
In this study, a novel polydopamine modified carboxymethyl chitosan molecularly imprinted resin (CMCS-MIR) was synthetized for selectively adsorbed and separated epicatechin (EC) from Rumex acetosa L. The preparation process involved modifying the surface of DM-130 resin to form the polydopamine (PDA) layer firstly, which facilitated an increase in adsorption sites. Subsequently, carboxymethyl chitosan (CMCS), a green functional monomer, was utilized along with glutaraldehyde as a crosslinking agent and EC as a template molecule to synthesize the CMCS-MIR. The synthesized CMCS-MIR exhibited an adsorption capacity of 53.30 mg·g −1 within 6 h and exhibited excellent selectivity and affinity towards EC (IF = 3.31). Moreover, the CMCS-MIR maintained stable adsorption performance and reusability with the adsorption efficiency remaining above 90 % in the fifth cycle. What's more, the CMCS-MIR can be used as a novel column filler in solid-phase extraction (SPE) to separate EC from extracts of Rumex acetosa L. roots. The adsorption recovery rate of EC is 89.56 %, the desorption recovery rate reaches 88.02 %. The DFT simulation and NMR experiments indicated that the predominant adsorption mechanism was due to the strong hydrogen bonding interactions. This work offers significant insights into the development of green molecularly imprinted materials with excellent selectivity and recognition capabilities.
研究领域:
材料科学
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分析化学
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天然产物化学
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吸附分离技术
✓ 已验证
产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）