ACS Omega
·
2024
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IF 3.7
Yun-qiong Yang,Yuan Zhang,Yang Liu,Feier Lin,Hao Zhang
The construction of tunable white-light-emitting materials has garnered increasing attention in the scientific community. In this study, N-doped carbon dots (N-CDs) were surface-modified with carboxylatopillar[5]arene (CP[5]) using an EDC–NHS coupling reaction to create CCDs. CCDs were then conjugated with rhodamine 6G (R6G) through host–guest interactions to fabricate the CCDs–R6G composites. These composites produced two-color fluorescence emission peaks at 447 and 557 nm when excited by a wavelength of 340 nm. Excitingly, white-light emission (0.28, 0.30) can be readily achieved by varying the R6G concentration. To further explore potential applications, a new detection method for rutin (RT) based on the inner filter effect (IFE) was developed. Experimental results verify the practicality and reliability of the fluorescence sensor based on CCDs–R6G composites for RT detection in real samples.
研究领域:
材料科学
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分析化学
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生物医学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
ANALYTICAL CHEMISTRY
·
2021
·
IF 6.986
Yamin Nie,Xiuli Tao,Haowen Zhang,Ya-qin Chai,Ruo Yuan
Ligand-protected gold nanoclusters (Au NCs) are promising electrochemiluminescence (ECL) emitters because of their striking optical properties and excellent biocompatibility, but free vibration and rotation of their ligand result in low ECL efficiency, dramatically limiting their applications. Herein, using the ligand of Au NCs as one of the building units, a Au NC-based metal–organic framework (Au NC-based MOF) was constructed by the coordination-assisted self-assembly strategy, which not only impedes the ligand rotation-induced energy dissipation but also diminishes the self-quenching effect due to the spatial distribution of Au NCs. As a proof of concept, the prepared GSH-Au NCs@ZIF-8 gives rise to a 10-fold enhanced anodic ECL efficiency compared to that of densely aggregated GSH-Au NCs with triethylamine as the coreactant. Based on high ECL efficiency of GSH-Au NCs@ZIF-8, a “signal off” sensing platform was proposed with rutin as a model analyte, achieving a low detection limit of 10 nM. Therefore, the strategy paves an effective and alternative methodology to enhance ECL efficiency of metal NCs, considerably broadening their potential applications in sensing analysis, clinical diagnosis, and light-emitting devices.
研究领域:
材料科学
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分析化学
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生物医学工程
✓ 已验证
产品关联
DOI
PubMed
高影响因子
SENSORS AND ACTUATORS B-CHEMICAL
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2020
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IF 7.1
Jiajia Xi,Hao Wang,Bihong Zhang,Faqiong Zhao,Baizhao Zeng
A molecularly imprinted polymer/Bi 2 S 3 /ZnIn 2 S 4 /ITO sensor was fabricated and used for the photoelectrochemical detection of rutin. The Bi 2 S 3 /ZnIn 2 S 4 composite was synthesized by solvothermal method and it displayed good photoelectrochemical property because of the matched energy levels of Bi 2 S 3 and ZnIn 2 S 4 . In addition, ZnIn 2 S 4 could improve the stability of the composite and avoid photocorrosion. The photocurrent signal of the Bi 2 S 3 /ZnIn 2 S 4 composite was much larger than that of Bi 2 S 3 and ZnIn 2 S 4 under visible-light irradiation. Moreover, rutin imprinted chitosan was prepared by mixing rutin and chitosan solutions, followed by simple cross-linking reaction with glutaraldehyde at room temperature. The molecularly imprinted material was combined with Bi 2 S 3 /ZnIn 2 S 4 /ITO to construct photoelectrochemical sensor, and the resulting sensor showed a low detection limit (i.e. 0.003 μM) and a wide detection range (i.e. 0.01–100.0 μM) for rutin. It also displayed high stability and selectivity. The sensor could be used for the detection of rutin in real samples.
研究领域:
分析化学
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材料科学
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药物分析
✓ 已验证
产品关联
DOI
高影响因子
MICROCHEMICAL JOURNAL
·
2024
·
IF 4.9
Rui Liu,Xin Zhang,Ri-jia Liu,Yuan Sun,Bin-qiao Ren
In this study, we created a brand-new g-C 3 N 4 -MWCNTs/Ag/β-CD-MOF electrode that can be used as a platform for the electrochemical sensing of Rutin (RT). The g-C 3 N 4 -MWCNTs/Ag/β-CD-MOF composite was synthesized via calcination treatment and electrodeposition, coupled with hydrothermal reaction. This composite could appreciably enlarge the electrochemically active surface area of the as-prepared sensor to promote electron transfer and result in the enhanced response signals.With the assistance of differential pulse voltammetry (DPV) and cyclic voltammetry (CV), the electrochemical performance of sensor can be greatly enhanced. Under these optimum conditions, the designed electrochemical sensor was able to sense RT at the lower detection limit (LOD) of 0.69 nM (S/N = 3) with a wider range of 5–500 nM and showed high sensitivity of 1.97 μA . nM −1. cm −2 at room temperature. Additionally, the selective investigation on RT was performed with the related interfering molecules, and the g-C 3 N 4 -MWCNTs/Ag/β-CD-MOF/GCE showed decent stability and reproducibility. The real-time application of the modified electrode for RT detection was monitored in both pharmaceutical and serum samples with the satisfactory recovery. Overall, this research contributes to the field of the electroanalytical sensing and offers the potential applications in the drug monitoring.
研究领域:
分析化学
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药物监测
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生物医学工程
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产品关联
DOI
高影响因子
JOURNAL OF THE ELECTROCHEMICAL SOCIETY
·
2021
·Vol. 168
·期 7
·077521
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IF 4.316
Rongqian Meng,Jianke Tang,Xiaojun Wu,Shengjian Zhang,Xin Wang,Qiaoling Li,Riya Jin
A molecularly imprinted polymer (MIP) with 3D worm-like nanorod structures was constructed by cyclic voltammetry (CV) polymerization, using 3,4-ethylenedioxythiophene (EDOT) and pyrrole (Py) as bifunctional monomers, and rutin as the template on a glassy carbon electrode (GCE). The optimum polymerization conditions of MIP were obtained by the orthogonal test. The range analysis suggested that the potential range was the most influential factor. Compared with MIP/1.5 and MIP/1.9, the MIP films prepared in the potential range of 0–1.7 V (MIP/1.7) had better current response to rutin, faster charge transfer rate and higher doping levels by differential pulse voltammetry (DPV), Chronocoulometry and X-ray photoelectron spectroscopy (XPS) analysis. Rutin could be detected in the concentration range of 0.5 nM to 1 μM, and 5 to 50 μM with the low detection limit as 0.24 nM (S/N = 3). Moreover, MIP/1.7 exhibited 3-fold increase current response toward rutin by DPV when compared with the corresponding non-imprinted polymer (NIP), revealing the success of the imprinting. This sensor also exhibited high selectivity, good long-term stability, and acceptable reproducibility. The rutin content in Flos Sophorae Immaturus (FSI) was 25.37% with good accuracy.
研究领域:
分析化学
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药物分析
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材料科学
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产品关联
DOI
高影响因子
Journal of Materials Chemistry B
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2020
·Vol. 8
·期 46
·10630-10636
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IF 5.344
Xinyu Ma,Wenyan Liao,Huaxu Zhou,Yun Tong,Fei Yan,Hongliang Tang,Jiyang Liu
Herein we report a simple and rapid approach to fabricate a vertically-ordered mesoporous silica–electrochemically reduced graphene oxide nanocomposite film (VMSF/ErGO) on an indium tin oxide (ITO) electrode surface by the electrochemically-assisted self-assembly (EASA) method, which is capable of greatly promoting the electroanalytical performance of rutin compared to the previously reported VMSF modified ITO electrode and, meanwhile, displaying excellent anti-fouling and anti-interference ability in pharmaceutical formulations and human serum. Due to the excellent electrocatalytic activity of ErGO and the synergistic enrichment effects from the π–π interaction of ErGO and the hydrogen bond effect from the VMSF, the present VMSF/ErGO/ITO sensor is able to detect rutin with a wide linear range, a high sensitivity and a low limit of detection. Moreover, the VMSF/ErGO/ITO electrode could retain the high sensing performance with high transmittance upon tailoring the concentration of the modified graphene oxide (GO), which provides a simple approach for modifying transparent ITO electrodes and could be potentially used for optoelectronic devices.
研究领域:
分析化学
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生物医学工程
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药物分析
✓ 已验证
DOI
高影响因子
MICROCHEMICAL JOURNAL
·
2025
·
IF 5.1
Xinyu Huang,Junhong Li,Huan Zhang,Xuemin Duan,Lihua Yao,Ruirui Yue,Jingkun Xu
As a natural flavonoid glycoside, rutin has been made into many medical products due to its unique pharmacological activity. However, excessive intake of rutin is harmful to health. Therefore, developing a new sensing technique to achieve highly sensitive, rapid and on-site detection of rutin is of great significance to ensure food and medicine safety. Herein, an electrochemical sensing platform was proposed based on the nanocomposite of functionalized multi-wall carbon nanotubes/poly(3,4-ethylenedioxythiophene):poly(styrenesulfonate)/Ru nanoparticles (MWCNT-COOH/PEDOT:PSS/Ru) for rutin detection. The characterization techniques reveal that MWCNT-COOH and PEDOT:PSS crossed together forming a 3D interconnecting structure with plenty of areolations and high specific surface area, and Ru nanoparticles uniformly dispersed on the surface of MWCNT-COOH/PEDOT:PSS. Moreover, due to the good film reforming property of PEDOT:PSS, the as-obtained MWCNT-COOH/PEDOT:PSS/Ru composite shows special surface appearance as flexible free-standing film, which can be freely cut and used as sensing platform directly. Electrochemical experiments confirmed that MWCNT-COOH/PEDOT:PSS/Ru composite film performed satisfactory sensing properties toward rutin detection with wide linear ranges of 0.01 ∼ 0.7 μM and 0.7 ∼ 50 μM, low detection limit of 6.1 nM and high sensitivity of 79.43 μA μM −1 cm −2 . Besides, the composite sensing platform also exhibits high selectivity, reproducibility, and stability. During actual sample testing, the sensing platform was successfully applied for rutin detection in rutin pharmaceutical tablets and black buckwheat tea, showing promising application prospects in rapid, convenient, and high-efficiency on-site test.
研究领域:
材料科学
·
分析化学
·
生物医学工程
✓ 已验证
产品关联
DOI
高影响因子
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