Materials
·
2018
·Vol. 11
·期 5
·836
·
IF 2.467
Tianxiang Li,Zhengren Shi,Xianru He,Ping Jiang,Xiaobin Lu,Rui Zhang,Xin Wang
With the aim of improving the anti-aging properties of nitrile-butadiene rubber (NBR), a functional organic filler, namely LDH–SAS, prepared by intercalating 4-amino-benzenesulfonic acid monosodium salt (SAS) into layered double hydroxides (LDHs) through anion exchange, was added to nitrile-butadiene rubber (NBR), giving the NBR/LDH–SAS composites. Successful preparation of LDH–SAS was confirmed by XRD, TGA and FTIR. LDH–SAS was well dispersed in the NBR matrix, owing to its strong interaction with the nitrile group of NBR. The obtained NBR/LDH–SAS composites exhibited excellent thermo-oxidative aging resistance as shown by TGA-DSC. Further investigation by ATR-FTIR indicated that SAS can capture the radical groups, even during the aging process, which largely accounts for the improved aging resistance.Keywords:layered double hydroxides (LDHs);nitrile-butadiene rubber (NBR);4-Amino-benzenesulfonic acid monosodium salt (SAS);thermal oxidative aging resistance properties
研究领域:
材料科学
·
聚合物化学
·
复合材料
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Nanomaterials
·
2020
·Vol. 10
·期 2
·322
·
IF 4.324
Lin-Fei Chen,Pei-Yao Xu,Chao-Ping Fu,Ranjith Kumar Kankala,Ai-Zheng Chen,Shi-Bin Wang
Due to its hydrophobicity, fisetin (FIS) often suffers from several limitations in terms of its applicability during the fabrication of pharmaceutical formulations. To overcome this intrinsic limitation of hydrophobicity, we demonstrate here the generation of poly (vinyl pyrrolidone) (PVP)-encapsulated FIS nanoparticles (FIS-PVP NPs) utilizing a supercritical antisolvent (SAS) method to enhance its aqueous solubility and substantial therapeutic effects. In this context, the effects of various processing and formulation parameters, including the solvent/antisolvent ratio, drug/polymer (FIS/PVP) mass ratio, and solution flow rate, on the eventual particle size as well as on distribution were investigated using a 23factorial experimental design. Notably, the FIS/PVP mass ratio significantly affected the morphological attributes of the resultant particles. Initially, the designed constructs were characterized systematically using various techniques (e.g., chemical functionalities were examined with Fourier-transform infrared (FTIR) spectroscopy, and physical states were examined with X-ray diffraction analysis (XRD) and differential scanning calorimetry (DSC) techniques). In addition, drug release as well as cytotoxicity evaluations in vitro indicated that the nanosized polymer-coated particles showed augmented performance efficiency compared to the free drug, which was attributable to the improvement in the dissolution rate of the FIS-PVP NPs due to their small size, facilitating a higher surface area over the raw form of FIS. Our findings show that the designed SAS process-assisted nanoconstructs with augmented bioavailability, have great potential for applications in pharmaceutics.Keywords:supercritical fluid technology;fisetin;nanofabrication;antitumor
研究领域:
药学
·
纳米技术
·
药物递送系统
·
癌症研究
·
超临界流体技术
·
材料科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF COLLOID AND INTERFACE SCIENCE
·
2024
·
IF 9.4
Yushun Wang,Xinzheng Zhang,Yuquan Yang,Huichao Wang,Woon-Ming Lau,Chenjing Wang,Zhongheng Fu,Dawei Pang,Qian Wang,Jinlong Zheng
The single atom catalysts (SACs) show immense promise as catalytic materials. By doping the single atoms (SAs) of precious metals onto substrates, the atomic utilization of these metals can be maximized, thereby reducing catalyst costs. The electronic structure of precious metal SAs is significantly influenced by compositions of doped substrates. Therefore, optimizing the electronic structure through appropriate doping of substrates can further enhance catalytic activity. Here, Pt single atoms (Pt SAs) are doped onto transition metal sulfide substrate NiS 2 (Pt SAs-NiS 2 ) and phosphide substrate Ni 2 P (Pt SAs-Ni 2 P) to design and prepare catalysts. Compared to the Pt SAs-NiS 2 catalyst, the Pt SAs-Ni 2 P catalyst exhibits better hydrogen evolution catalytic performance and stability. Under 1 M KOH conditions, the hydrogen evolution mass activity current density of the Pt SAs-Ni 2 P catalyst reaches 0.225 A mg Pt –1 at 50 mV, which is 33 times higher than that of commercial Pt/C catalysts. It requires only 44.9 mV to achieve a current density of 10 mA cm −2 . In contrast, for the Pt SAs-NiS 2 catalyst, the hydrogen evolution mass activity current density is 0.178 A mg Pt –1 , requiring 77.8 mV to achieve a current density of 10 mA cm −2 . Theoretical calculations indicate that in Pt SAs-Ni 2 P, the interaction between Pt SAs and the Ni 2 P substrate causes the Pt d-band center to shift downward, enhancing the H 2 O desorption and providing optimal H binding sites. Additionally, the hollow octahedral morphology of Ni 2 P provides a larger surface area, exposing more reactive sites and improving reaction kinetics. This study presents an effective pathway for preparing high-performance hydrogen evolution electrocatalysts by selecting appropriate doped substrates to control the electronic structure of Pt SAs.
研究领域:
材料科学
·
电化学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
SEPARATION AND PURIFICATION TECHNOLOGY
·
2021
·
IF 7.312
Xuefeng Xiao,Yongjun Sun,Jianwen Liu,Huaili Zheng
Two bioflocculants of starch-graft-P[acrylamide-acrylic acid] (SAA) and starch-graft-P[acrylamide-2-acacrylamido-2-methyl-1-propanesulfonic acid] (SAS) are designed for the flocculation–chelation of heavy metals. The successful polymer synthesis is confirmed through physicochemical characterization. SAA and SAS are used to remove Cu(II), Zn(II), and Ni(II) from simulated wastewater and Ni(II) from actual electroplating wastewater. The removal efficiencies for Cu(II), Zn(II), and Ni(II) in the simulated wastewater by SAA and SAS are more than 80.00%, whereas those for Ni(II) are more than 90.0% in the Ni-containing electroplating wastewater at the optimal condition. Flocculation experiments reveal that the sulfonate structure of SAS is highly conducive to improve flocculation efficiency. SAA and SAS have high selectivities for Cu(II) in the simulated water sample with mixed heavy metal. Finally, the 3E (i.e., environmental impact, economic benefit, and energy consumption) triangular evaluation model is established to evaluate the flocculation experiments for the removal of heavy metal ions using SAA and SAS.
研究领域:
环境科学
·
材料科学
✓ 已验证
产品关联
DOI
高影响因子
IEEE PHOTONICS TECHNOLOGY LETTERS
·
2015
·Vol. 27
·期 22
·2379-2382
·
IF 2.11
Duanduan Wu,Zhiping Cai,Yile Zhong,Jian Peng,Jian Weng,Zhengqian Luo,Nan Chen,Huiying Xu
Passive Q-switching of praseodymium (Pr
3+
)-doped fiber lasers at 635 nm with topological insulators (TIs) saturable absorbers (SAs) was experimentally demonstrated for the first time. TIs (Bi
2
Se
3
, Bi
2
Te
3
) nanosheets were embedded in polyvinyl alcohol for film-forming and incorporated into a visible Pr
3+
-doped fiber laser cavity for Q-switching operation, respectively. The Bi2Se3-based Q-switched fiber laser has a wide range pulse-repetition-rate from 191.6 to 454.5 kHz, and the Bi2Te3 one can be continuously tuned from 164.5 to 403.2 kHz. Both the Q-switching lasers have narrow pulse duration of nanosecond (ns)-level. Our results reveal that the TIs-based SAs are available for pulsed operation in the visible spectral range.
研究领域:
光学工程
·
激光技术
·
材料科学
·
纳米技术
·
量子电子学
✓ 已验证
DOI
高影响因子
RSC Advances
·
2015
·Vol. 5
·期 99
·81388-81394
·
IF 3.84
Shu-Jun Wang,Bei-Bei Wang,Feng-Wu Bai,Xiao-Jun Ma
Mass production of carbon dots (CDs) derived from chondroitin sulfate (CS) was developed by the facile hydrothermal approach for the first time. The CS derived CDs (CSCDs) possessed good dispersibility and water solubility, bright blue and green luminescence, and relative pH- and photo-stable properties. Moreover, the multicolor CSCDs could be efficiently uptaken by SAS cells and exhibited low cytotoxicity. Therefore, the responses of human oral squamous cell carcinoma SAS cells to CSCDs were further investigated by evaluating their proliferation and invasion. Compared to CS, CSCDs not only provided higher efficiency for proliferation of SAS cells, and up-regulated expression of matrix metalloproteinases to mimic extracellular matrix secretion, but also portrayed fluorescence for labeling SAS tumor cells. Hence, the multifunctional CSCDs are expected to have potential for biomedical applications.
研究领域:
生物医学工程
·
癌症研究
·
纳米技术
·
细胞生物学
✓ 已验证
产品关联
DOI
高影响因子
Nature Communications
·
2023
·Vol. 14
·期 1
·1-15
·
IF 16.6
Huang Sha,Ma Yu,Xu Yitian,Lu Pengfei,Yang Jie,Xie Yu,Gan Jianhua,Li Lin
For shade-intolerant species, shade light indicates the close proximity of neighboring plants and triggers the shade avoidance syndrome (SAS), which causes exaggerated growth and reduced crop yield. Here, we report that non-secreted ROT FOUR LIKE (RTFL)/DEVIL (DVL) peptides negatively regulate SAS by interacting with BRASSINOSTEROID SIGNALING KINASEs (BSKs) and reducing the protein level of PHYTOCHROME INTERACTING FACTOR 4 (PIF4) in Arabidopsis. The transcription of at least five RTFLs ( RTFL13/16/17/18/21 ) is induced by low R:FR light. The RTFL18 (DVL1) protein is stabilized under low R:FR conditions and localized to the plasma membrane. A phenotype analysis reveals that RTFL18 negatively regulates low R:FR-promoted petiole elongation. BSK3 and BSK6 are identified as partners of RTFL18 through binding assays and structural modeling. The overexpression of RTFL18 or knockdown of BSK3/6 reduces BRASSINOSTEROID signaling and reduces low R:FR-stabilized PIF4 levels. Genetically, the overexpression of BSK3/6 and PIF4 restores the petiole phenotype acquired by RTFL18 -overexpressing lines. Collectively, our work characterizes a signaling cascade (the RTFLs-BSK3/6-PIF4 pathway) that prevents the excessive activation of the shade avoidance response in Arabidopsis.
研究领域:
植物生物学
·
分子遗传学
✓ 已验证
DOI
PubMed
高影响因子
JOURNAL OF SUPERCRITICAL FLUIDS
·
2020
·
IF 3.744
Pei-Yao Xu,Chao-Ping Fu,Ranjith Kumar Kankala,Shi-Bin Wang,Ai-Zheng Chen
Owing to its poor solubility, the applicability of dihydromyricetin (DMY) is limited in various biomedical applications. To overcome this issue, nano-sized DMY particles (DMY NPs) were fabricated using the supercritical antisolvent (SAS) approach for improving the bioavailability of DMY. Initially, the experimental conditions were optimized such as temperature of 45 °C, pressure of 8 MPa, and DMY solution flow rate of 0.5 mL/min, resulting in the DMY particles at a mean particle size of 169.1 ± 23.7 nm. Further, the physicochemical characteristics of the resultant DMY NPs were evaluated using various characterization techniques. The DMY NPs with reduced particle size and improved dissolution rate resulted in improved anticancer, antibacterial, and biofilm inhibition efficacies, comparable to that of unprocessed DMY. Together, the designed DMY NPs using the SAS process have great potential in food and pharmaceutical industries.
研究领域:
药学
·
纳米技术
·
生物医学工程
·
化学工程
✓ 已验证
DOI
高影响因子
Phenomics
·
2022
·Vol. 2
·期 2
·119-129
·
IF 0
Huang Sha,Yang Chuanwei,Li Lin
For shade-intolerant plants, a reduction in the red/far-red (R:FR) light ratio signals the close proximity of competitors and triggers shade-avoidance syndrome (SAS). Auxin, brassinosteroid, gibberellin and some transcriptional regulators have been reported to regulate shade-induced hypocotyl elongation. However, little is understood regarding the coordination of these multiple regulatory pathways. Here, combining time-lapse growth rates and transcriptomic data, we demonstrate that auxin and brassinosteroid affect two phases of shade-induced rapid growth, whereas gibberellin mainly contributes to the second rapid growth phase. PHYTOCHROME-INTERACTING FACTOR 7 (PIF7) acts earlier than other PIFs. PIF4 and PIF5 modulate the second rapid growth phase. LONG HYPOCOTYL IN FAR-RED 1 (HFR1) and PIF3-LIKE 1 (PIL1) modulate two rapid growth phases. Our results reveal that hormonal and transcriptional regulatory programs act together to coordinate dynamic hypocotyl changes in an immediate response to a shade signal and provide a novel understanding of growth kinetics in a changing environment.
研究领域:
植物生物学
·
分子生物学
·
植物生理学
✓ 已验证
DOI
PHYSICAL CHEMISTRY CHEMICAL PHYSICS
·
2014
·Vol. 16
·期 48
·26917-26928
·
IF 4.198
Mingguang Li,Jiangang Liu,Xinxiu Cao,Ke Zhou,Qiaoqiao Zhao,Xinhong Yu,Rubo Xing,Yanchun Han
Herein, balanced intermixed and pure crystalline phases in N,N′-bis(1-ethylpropyl)-perylene-3,4,9,10-tetracarboxylic diimide (EP-PDI)-based non-fullerene organic solar cells (OSCs) were achieved via selective solvent additives (SAs). Poly[[4,8-bis[(2-ethylhexyl)oxy]benzo[1,2-b:4,5-b′]dithiophene-2,6-diyl][3-fluoro-2-[(2-ethylhexyl)carbonyl]thieno[3,4-b]thiophenediyl]] (PTB7) and 7,7′-(4,4-bis(2-ethylhexyl)-4H-silolo[3,2-b:4,5-b′]dithiophene-2,6-diyl)bis(6-fluoro-4-(5′-hexyl-[2,2′-bithiophen]-5-yl)benzo[c][1,2,5]thiadiazole) (F-DTS) possessing different compatibilities with EP-PDI were selected as model systems to investigate the guideline of SAs selection for different non-fullerene-based systems. According to the solubility parameter difference (Δδ) between EP-PDI and SAs, five different SAs were divided into two types: (I) strong intermolecular interactions with EP-PDI molecules (with Δδ values less than 5 MPa1/2), (II) weak intermolecular interactions with EP-PDI molecules (with large Δδ values). For PTB7:EP-PDI system with large and obvious phase separation, the introduction of type (II) SAs provided extra interactions with EP-PDI molecules, thus effectively reducing EP-PDI aggregate domains and increasing intermixed fractions. The incorporation of type (II) SAs resulted in a greater yield of dissociated polarons, and the final device efficiency increased from 0.02% to 1.65%. On the contrary, for finely mixed F-DTS:EP-PDI systems, type (I) SAs were considerably more effective because of the fact that the required pure crystalline phases were readily induced by the unfavorable interactions. The charge transport pathways optimized by type (I) SAs improved device efficiency from 0.18% to 2.82%. Hence, by processing selective SAs, the fraction of intermixed and pure crystalline phases for PDI-based non-fullerene OSCs can be well regulated; therefore, the final performance for both systems can be significantly improved.
研究领域:
材料科学
·
有机电子学
·
太阳能
✓ 已验证
产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）