Food Analytical Methods
·
2022
·Vol. 15
·期 8
·2346-2356
·
IF 3.498
Agyekum Akwasi Akomeah,Kutsanedzie Felix Y. H.,Mintah Benjamin Kumah,Annavaram Viswadevarayalu,Braimah Alberta Osei
Norfloxacin is an antibiotic in the fluoroquinolone family licenced for use in animals. However, residues in animal products can have negative consequences for consumers. As a result, residue detection in various food matrices must be considered. Norfloxacin accumulates in animal-derived foods, causing deleterious consequences in humans such as foetal deformity, renal failure and drug resistance. A built-in SERS-Au@Ag nanosensor coupled with GA-PLS was used to rapidly detect norfloxacin in the specimen of the spiked fish muscles due to the threat to human lives. A detection limit of 2.36 × 10 −5 μg/mL was realized in the spiked fish muscle sample for norfloxacin compared to the European Commission’s maximum threshold level of 100 μg/kg, indicating the sensor’s ability to detect and quantify norfloxacin at a relatively lower level. The recovery rates (RC) and coefficient of variation (CV) measured in the spiked fish muscle samples for norfloxacin analytes and their standard solutions were between 99.70–105.00% and 0.17–5.21%, respectively. The low CV values imply the reproducibility of the obtained data. The constructed model recorded residual predictive deviations (RPD) greater than three (3), demonstrating the robustness and resilience of the developed genetic algorithm-partial least squares (GA-PLS) model. GA-PLS-built models predicted all results within 4.07 s, which indicates the nanosensor’s ability to rapidly detect norfloxacin in fish to guarantee safety and public health. The SERS probe holds promise for rapid quantification of norfloxacin at microgram per milliliter level in fish to guarantee safety in commerce. Graphical abstract
研究领域:
食品安全
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分析化学
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纳米技术
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药理学
✓ 已验证
DOI
高影响因子
TALANTA
·
2024
·
IF 5.6
Yueshou Zhang,Lichun Yang,Yulin Xu,Haiting Ren,Shi Yin,Yan Sun,Yongjun Hu
Rapid and sensitive detection of phosphate is of great significance for ensuring water safety and preventing eutrophication. In this study, we prepared Au@PATP@Ag NRs core-shell structures using 4-aminothiophenol (PATP) as an internal standard signal molecule to enhance the stability of the SERS signal. Based on the phosphate-induced decomposition of ZIF-8 and the protective effect of ZIF-8 on the internal Au@PATP@Ag NRs, a phosphate SERS sensor (Au@PATP@Ag@ZIF-8) with high sensitivity, selectivity and stability was designed. This method exhibited a good linear range of 0.1–125 μM and a detection limit of 30 nM. Furthermore, the developed sensor (Au@PATP@Ag@ZIF-8) was effectively applied to assess PO 4 3− in tap water samples, achieving recoveries between 97.44% and 104.54%. With its simple, fast and sensitive features, this method of phosphate detection in water provides a direction for the research and practical application of phosphate detection.
研究领域:
环境科学
·
分析化学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
·
2024
·
IF 4.3
Huanhuan Li,Wei Sheng,Md. Mehedi Hassan,Wenhui Geng,Quansheng Chen
The abuse of antibiotics has caused gradually increases drug-resistant bacterial strains that pose health risks. Herein, a sensitive SERS sensor coupled multivariate calibration was proposed for quantification of antibiotics in milk. Initially, octahedral gold-silver nanocages (Au@Ag MCs) were synthesized by Cu 2 O template etching method as SERS substrates, which enhanced the plasmonic effect through sharp edges and hollow nanostructures. Afterwards, five chemometric algorithms, like partial least square (PLS), uninformative variable elimination-PLS (UVE-PLS), competitive adaptive reweighted sampling-PLS (CARS-PLS), random frog-PLS (RF-PLS), and convolutional neural network (CNN) were applied for TTC and CAP . RF-PLS performed optimally for TTC and CAP (Rc = 0.9686, Rp = 0.9648, RPD = 3.79 for TTC and Rc = 0.9893, Rp = 0.9878, RPD = 5.88 for CAP). Furthermore, the detection limit of 0.0001 µg/mL for both TTC and CAP was obtained. Finally, satisfactory ( p > 0.05) results were obtained with the standard HPLC method. Therefore, SERS combined RF-PLS could be applied for fast, nondestructive sensing of TTC and CAP in milk.
研究领域:
分析化学
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食品科学
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生物医学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
·
2021
·
IF 4.098
Wenxian Wei,Dan Yu,Yu Du,Yicheng Ding,Qingli Huang
Au-Ag alloy nanoparticles (NPs) with controllable size and composition were synthesized by a facile, one-pot hydrothermal method. Various characterization techniques including TEM, UV–vis, EDX, HAADF-STEM and XPS were used to discuss the influencing factors for the size and composition of Au-Ag alloy NPs. It is obvious that the size and composition of Au-Ag alloy NPs could be adjusted by the experimental parameters. Catalytic and SERS performance of the Au-Ag alloy NPs were further investigated. Ideal catalytic and SERS performance could be also obtained via optimizing the size and composition of Au-Ag alloy. This work is of importance in theory research and practical application of the noble metal nanocomposites.
研究领域:
材料科学
·
化学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
FOOD CHEMISTRY
·
2025
·
IF 9.8
Xishun Peng,Yiheng Yuan,Anjiang Lu,Cunwei Wang,Caizhen Zu,Haili Zhang,Zhongchen Bai
Glyphosate (Gly) residues in agricultural products have a serious health risk, so it is urgent to seek a sensitive and convenient method for recognizing Gly residues in food. In this study, we proposed an electrochemical surface-enhanced Raman spectroscopy (EC-SERS) sensor of polyaniline/reduced graphene oxide/Ag/Cu (PANI/RGO/Ag/Cu) film to detect Gly residues. The EC-SERS sensor of PANI/RGO/Ag/Cu film had a large specific surface area, which could increase the binding sites of cu 2+ /Gly clathrates for boosting specifically its SERS signal. Moreover, Ag/Cu nanoparticles on the surface of film could effectively increase the differential pulse voltammetry signal and SERS signal of Gly molecules. The limit of detection of EC-SERS sensor to Gly could reach 1.9 nM. In addition, the EC-SERS sensor we prepared could also sensitively identify Gly residues on fresh fruit peels. The PANI/RGO/Ag/Cu film we proposed in this paper has great potential for selective and accuracy detecting Gly residues in agricultural products.
研究领域:
食品科学
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分析化学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Biosensors-Basel
·
2025
·Vol. 15
·期 7
·426
·
IF 5.6
Kai Hua,Liang Li,Pei Liang
MXenes are a class of two-dimensional materials exhibiting excellent surface-enhanced Raman scattering (SERS) performance. Currently, the SERS studies of MXenes have been primarily focused on those with M2X and M3X2structural motifs. In order to expand the SERS sensing application based on MXenes, in this paper, a SERS sensor made of Ta4C3@AgNP nanocomposite material was fabricated by electrostatic self-assembly. Tests such as different concentrations of R6G probe molecules showed that the minimum detection limit of this SERS sensor was 10−8M, demonstrating excellent sensitivity. When different test areas are selected, the relative error of intensity under the same wave number is less than 10.7%, showing good repeatability and consistency. Furthermore, the Ta4C3@AgNP nanocomposite SERS sensor was used to detect the pesticide Ziram, and a quantitative model was established. Application detection indicates that this sensor has good sensitivity for the pesticide Ziram, and the minimum detection limit was 10−6M, which exceeded national standard requirements. The findings of this study have potential application value in the fields of food safety and environmental protection.
研究领域:
分析化学
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材料科学
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食品安全
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环境监测
✓ 已验证
产品关联
DOI
PubMed
高影响因子
TALANTA
·
2023
·
IF 6.1
Shuyan Ruan,Ru Liu,Xi Chen,Qian Huang,Chongxin Xiao,Ruiyun You,Luqiang Huang,Yunzhen Liu,Jingbo Chen,Xiufeng Xiao,Qingqiang Lin,Yudong Lu
As a reactive oxygen species (ROS), excessive production of H 2 O 2 contributes to the development of several diseases such as, inflammation, cancer, and respiratory diseases. Supplementation with endogenous or exogenous antioxidants can scavenge ROS and reduce the oxidation of cellular molecules, thus alleviating the generation of diseases. Therefore, the determination of H 2 O 2 content and its antioxidant activity is of great importance in disease diagnosis and treatment. In this paper, a ratiometric SERS sensor with a flexible cellulose membrane was designed for quantitative detection of H 2 O 2 and assessment of antioxidant activity. First, gold seeds were reduced on bacterial cellulose membrane (BCM) and Au NPs were smoothly deposited on the bacterial cellulose membrane (BCM) using halides to reduce the reduction potential in the growth solution to form a flexible BCM@Au NPs SERS substrate. Afterwards, the oxidation of H 2 O 2 was used to convert 3-mercaptophenylboronic acid (3-MPBA) to the corresponding phenol form 3-hydroxyphenylethanol (3-HTP). The change of substance resulted in a good linear relationship between the intensity ratio corresponding to the two Raman shifts of 881 cm −1 and 995 cm −1 and the H 2 O 2 concentration with a detection limit of 0.0186 μM. This opens up a new method for the detection of H 2 O 2 with high sensitivity and accuracy. In addition, this SERS platform was successfully used for the determination of antioxidant activity. It is promising to be applied to disease diagnosis and efficacy evaluation.
研究领域:
分析化学
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生物医学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
ACS Applied Nano Materials
·
2024
·
IF 5.3
Yahui Zhang,Xia Huang,Jiachang Chen,Jiyuan Li,Shen Zhou,Junying Chen
Quantitative analysis of harmful patina components on the surface of bronzeware is crucial as patina can corrode artifacts. Surface-enhanced Raman spectroscopy (SERS) has a common application in surface analysis. However, there exists an absence of documented investigations concerning the quantitative analysis of detrimental patina, particularly the chloride patina. To achieve high sensitivity in targeting harmful patina, we report a fabrication method for constructing Ag/Au alloys in the pores and on the surface of UiO-66 (zirconium 1,4-dicarboxybenzene metal–organic framework) nanomaterials, resulting in Ag/Au/UiO-66 nanoparticle monolayers formed by self-assembly at the oil–water interface. By incorporating them onto the surface of PVA hydrogel, we obtained SERS sensor devices with excellent flexibility, outstanding optical transparency, and ultrahigh activity. These sensor devices efficiently sample irregular surfaces and detect micrometer-scale specimen. They significantly enhance the Raman characteristic peaks of measured objects, facilitating precise analysis of the patina composition on the surface of bronze artifacts. The Raman peak at 118 cm–1 was boosted from 367 to 11,909 for detecting harmful patina, and the enhancement factor of the SERS substrate was calculated to be 3.6 ×1010 for detecting the Raman peak of rhodamine 6G (R6G), which could be easily detected at 610 cm–1 at a concentration of 10–13 mol/L (M). The Raman peaks at 610 cm–1 from the SERS substrate could also be readily detected. By grafting the organic fluorescent group amino-MQAE onto the surface of Ag/Au/UiO-66 nanoparticles (NPs), the content of harmful patina on the surface of bronze artifacts treated for different durations was indirectly determined. These results indicate the successful construction of the Ag/Au alloy on the surface of UiO-66 NPs, resulting in SERS sensor devices with excellent flexibility, optical transparency, and ultrahigh sensitivity.
研究领域:
材料科学
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考古学
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光谱学
✓ 已验证
产品关联
DOI
高影响因子
SENSORS AND ACTUATORS B-CHEMICAL
·
2021
·
IF 7.46
Qiao-Yan Jiang,Ding Li,Yuhui Liu,Zheng-Sheng Mao,Youjia Yu,Ping Zhu,Qilan Xu,Yang Sun,Li Hu,Jie Wang,Jin Chen,Feng Chen,Yue Cao
A novel, recyclable, portable, and low-cost SERS sensor-AuBPs@MoS 2 @tinfoil box is fabricated layer-by-layer by self-assembly method for the first time, which achieved the purpose of high throughput SERS tracking. Diquat (DQ) is one of the most widely used herbicides in the world since paraquat was banned. Benefiting from the “hot spots” generated by AuBPs@MoS 2 , the sensor successfully realizes straightforward SERS recognition of DQ in complex compounds, which detection limit is as low as 1.0 × 10 −15 M. The preprocessing is not required for the detection of real samples, which promotes the practical application of forensic medicine and environmental engineering.
研究领域:
环境科学
·
分析化学
✓ 已验证
产品关联
DOI
高影响因子
ANALYTICAL CHEMISTRY
·
2024
·
IF 6.7
Biao Zhang,Jun Cao,Si-Jie Liao,Peng-Cheng Zhou,Yu-Ting Shen,Wei Yu,Wei Li,Ai-Guo Shen
At present, there is a lack of sufficiently specific laboratory diagnostic indicators for schizophrenia. Serum homocysteine (Hcy) levels have been found to be related to schizophrenia. Cysteine (Cys) is a demethylation product in the metabolism of Hcy, and they always coexist with highly similar structures in vivo. There are few reports on the use of Cys as a diagnostic biomarker for schizophrenia in collaboration with Hcy, mainly because the rapid, economical, accurate, and high-throughput simultaneous detection of Cys and Hcy in serum is highly challenging. Herein, a click reaction-based surface-enhanced Raman spectroscopy (SERS) sensor was developed for simultaneous and selective detection of Cys and Hcy. Through the efficient and specific CBT-Cys click reaction between the probe containing cyan benzothiazole and Cys/Hcy, the tiny methylene difference between the molecular structures of Cys and Hcy was converted into the difference between the ring skeletons of the corresponding products that could be identified by plasmonic silver nanoparticle enhanced molecular fingerprint spectroscopy to realize discriminative detection. Furthermore, the SERS sensor was successfully applied to the detection in related patient serum samples, and it was found that the combined analysis of Cys and Hcy can improve the diagnostic accuracy of schizophrenia compared to a single indicator.
研究领域:
医学诊断
·
分析化学
·
生物医学工程
✓ 已验证
产品关联
DOI
PubMed
高影响因子
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
·
2022
·
IF 4.831
Zhengdong Zhu,Xiaoyi Shi,Yating Feng,Meng He,Cheng Ye,Hongyang Zhou,Maofeng Zhang,Wei Zhang,Jianhua Li,Changlong Jiang
Conventional surface-enhanced Raman scattering (SERS) molecular detection are based on hard and brittle substrate, which are not suitable for in-situ detection of analytes adsorbed on nonplanar surfaces. Here, we report a simple biomimetic synthesis method to fabricate lotus leaf mastoid structured AgNPs micro/nanoarrays as reliable SERS substrate. By ideal replicating mastoid structure of lotus leaf into a flexible and transparent PDMS film, followed by depositing plasmonic AgNPs, a powerful chemical sensor with high sensitivity and multiplex detecting capability is demonstrated. The employ of periodic mastoid structure array endows the sensor with high signal repeatability (RSD ∼ 8.6 %), solving the general repeatability problem of SERS substrates. In addition, the detailed designed flexible and transparent PDMS substrate is capable of identifying trace analytes on curved surfaces with excellent durability. In the proof-of-concept experiment, a limit of detection (LOD) of (10 −5 M to 10 −7 M) was achieved on a portable Raman device for three common pesticides residues (thiram, fonofos and triadophos) on dendrobium leaves and stem according to the molecular fingerprint, indicating its excellent in-situ detection capability. Further, the multiplex detection ability of the Ag/PDMS film is also demonstrated by analyzing the mixture of four typical analytes. Benefiting from its high signal uniformity, this flexible Ag/PDMS substrate also showed good quantitative detection capabilities.
研究领域:
材料科学
·
分析化学
·
环境科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
TALANTA
·
2025
·
IF 6.1
Ao Chen,Yiwen Gui,Kuang Luo,Ning Cai,Jumei Li
In this study, a novel magnetic composite, Ag@Fe 3 O 4 /UiO-66-NH 2 (Ag@FUN), was developed by incorporating a porous metal-organic framework (MOF), UiO-66-NH 2 , which offers selective enrichment capabilities and facilitates solar-driven photoreduction of Cr(VI). The surface coverage of silver nanoparticles on Ag@FUN was precisely controlled by adjusting the AgNO 3 feed concentration, enabling tunable SERS sensitivity. SERS measurements revealed that the Ag@FUN composites exhibited strong signal intensity for Cr(VI), along with excellent signal reproducibility and storage stability. These composites were capable of detecting Cr(VI) at concentrations of as low as 7.81 × 10 -8 M in tap water and 8.89 × 10 -8 M in pond water. The remarkable SERS performance is attributed to the porous MOF structure, which enriches Cr(VI) via Zr–O coordination, electrostatic interactions, and pore-filling effects. Importantly, under simulated sunlight, Ag@FUN effectively reduced Cr(VI) within 70 minutes. The composites also demonstrated outstanding recyclability, retaining their SERS sensitivity and photocatalytic efficiency through five consecutive "detection–reduction" cycles. Overall, the Ag@FUN composites developed in this work exhibit high SERS sensitivity and robust photocatalytic activity, offering significant potential for environmental monitoring and ecological remediation.
研究领域:
环境科学
·
材料科学
·
分析化学
·
纳米技术
✓ 已验证
产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）