CHEMICAL PHYSICS LETTERS
·
2021
·
IF 2.328
Qianqian Shang,Xin Tan,Mingcan Chen,Songyue Han,Tao Yu
High-efficient SERS substrates containing dense hot spots were fabricated by assembling 3D Ag nanoflowers (AgNFs)@Au-FTO substrate by using citrate ions as the shape-guiding agent. The vertical growth of 3D AgNFs could be attributed to the synergistic effects of the concentration gradient layer of Ag + and the density gradient of the charge carrier. Combined with the simulation result of FDTD method, the enhanced SERS sensitivity and repeatability of AgNFs@Au-FTO could be attributed to the enlarged specific surface area, and the improved density of hot spots contributed by the overlap between the vertically stacked AgNSs with a high population of sharp edges.
研究领域:
材料科学
·
分析化学
✓ 已验证
产品关联
DOI
高影响因子
FOOD CONTROL
·
2021
·
IF 5.548
Alberta Osei Barimah,Zhiming Guo,Akwasi A. Agyekum,Chuang Guo,Ping Chen,Hesham R. El-Seedi,Xiaobo Zou,Quansheng Chen
Arsenic (As) is one of the toxic, persistent, and lethal heavy metalloids and requires rapid, less costly, and sensitive detection methods. This study proposed a label-free cuprous oxide/silver (Cu 2 O/Ag) surface-enhanced Raman scattering (SERS) nanoprobe to detect total As in tea. Different total As spiked tea concentrations were mixed with the Cu 2 O/Ag SERS nanoprobe for the SERS detection. Quantitative models were established for predicting the total As in tea by comparatively applying chemometric algorithms. Amongst the algorithms, competitive adaptive reweighted sampling partial least squares (CARS-PLS) optimized the most effective spectral variables to predict the total As in tea efficiently. The CARS-PLS gave the highest correlation coefficient value (R p = 0.9935), very low root means square error (RMSEP = 0.0496 μg g −1 ) in the prediction set and recorded the highest RPD value of 8.819. The proposed nanoprobe achieved a lower detection limit (0.00561 μg g −1 ), excellent selectivity, satisfactory reproducibility, and stability. No significant difference was recorded when the performance of the Cu 2 O/Ag total As SERS sensor was compared with the inductively coupled plasma mass spectrometry (ICP-MS) method. Therefore, this developed Cu 2 O/Ag coupled chemometrics SERS sensing method could be used to efficiently determine, quantify, and predict total As in tea to promote monitoring of heavy metal contaminants.
研究领域:
食品科学
·
分析化学
·
环境科学
✓ 已验证
DOI
高影响因子
Micro & Nano Letters
·
2018
·Vol. 13
·期 6
·868-871
·
IF 0.841
Yan-meng Li,Li-wei Wang,Ruo-ping Li,Jun-he Han,Ming-ju Huang
Malachite green (C 23 H 25 ClN 2 ) is an illegal fungicide of aquatic products due to its potential carcinogenic, teratogenic, and mutagenic effects. It is typically challenging to detect C 23 H 25 ClN 2 in fish with conventional techniques. The study reported a simple and rapid method for detecting C 23 H 25 ClN 2 on fish surface with surface-enhanced Raman scattering (SERS). Using the seed growth method with trometamol as the modifier, 110 nm in-diameter gold nanoparticles on thin glass as SERS substrate were prepared, which exhibited high SERS activity, reproducibility, stability, and flexibility in SERS measurement. The fish samples required no pretreatment and the entire measurement took <5 min. Quantitative analyses were also conducted. Excellent linear relationships ( R 2 = 0.9397–0.9977) were obtained between the concentrations and the peak intensities of C 23 H 25 ClN 2 at some characteristic peaks with a wide concentrations range (0.5–10 μM). The detection limit can reach 0.5 μM. This method provided an easy and fast way to detect C 23 H 25 ClN 2 on fish surface for food safety.
研究领域:
分析化学
·
食品科学
·
环境科学
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF ALLOYS AND COMPOUNDS
·
2023
·
IF 6.2
Wenqian Yan,Wen Ai,Wei Liu,Zhiyang Zhao,Xiaohui Hu,Sheng Cui,Xiaodong Shen
SnO 2 is a charming contributor to sensors, while the intrinsic deficiencies, like facile conglomeration, hard stimulation, and poor stability, limit its potential prospects. The SnO 2 aerogel (SA) is proposed through an achievable fabrication, effectively solving the difficulties and exhibiting a satisfactory ability in ethanol detection. The SA450 behaves as the spearhead, which owns the narrowest bandgap of 3.2 eV and the largest double-layer capacitance of 559 μF/cm 2 , symbolizing the most prone electronic transitions and active sites. Besides, SEM, TEM , and AFM are served to obtain the nanoparticle size and the rough surface. The SA450 exhibits an outstanding sensing ability at 150 ℃, and the DFT calculation is taken as evidence. Interestingly, the SA0 without calcination can exhibit a satisfying SERS detection towards 4-MBA, which applies to explosive detection. Finally, the bandgap structure and response process are discussed. This work introduces a brand-new preparation of metal oxide semiconductors (MOSs), overcoming plenty of aporias in gas sensors and simultaneously producing the SERS response, which can lead to a fresh direction for sensing materials.
研究领域:
材料科学
·
传感器技术
·
表面增强拉曼光谱
✓ 已验证
产品关联
DOI
高影响因子
ACS Applied Nano Materials
·
2023
·
IF 5.9
Ya Lu,Zhuanfang Bi,Guangyi Shang
Fluorene, as one of the important organic compounds widely used in the field of medicine and photoelectric materials, could damage human health even if it is extremely low in the environment. The development of ultrasensitive and easy-recyclable surface-enhanced Raman scattering (SERS) detection of trace fluorene is highly desired. In this work, a nanocomposite of Ag nanoparticles (Ag NPs) and porous g-C3N4 is synthesized by a facile method. The advantageous features of the as-prepared nanocomposite include a high SERS sensitivity due to the plasmonic effect of the Ag NPs, excellent recyclability due to the self-cleaning ability originating from the photocatalytic degradation of porous g-C3N4 under visible light irradiation, and good adsorption due to the large specific surface area of porous g-C3N4. The experimental results show that an ultralow detection limit of 1.35 × 10–13 M for R6G can be achieved. Especially, the nanocomposite exhibits excellent performance for the detection of fluorene with the detection limit of 3.11 × 10–11 M and multidetection of at least 13 cycles. The present research provides a nanocomposite with excellent synergistic activity of plasmonic enhancement and photocatalytic degradation for the recyclable SERS detection of trace fluorene.
研究领域:
材料科学
·
环境科学
·
分析化学
✓ 已验证
产品关联
DOI
高影响因子
TALANTA
·
2025
·
IF 6.1
Shuojiang Liu,Ying Chen,Xingliang Cheng,Gongke Li,Yuling Hu
Surface-enhanced Raman scattering (SERS) in conjunction with nanozymes has emerged as a powerful technique for bioanalysis due to their signal conversion and amplification effect. However, clinical applications continue to encounter challenges such as inadequate selectivity. Herein, we proposed a novel approach for the selective SERS detection of L-DOPA in human serum with dual enzyme-mimicking MOF-919(Fe–Cu). This material exhibits both catechol oxidase-like and peroxidase-like activities, enabling it to catalyze catecholic compounds to o -quinones and subsequently oxidize 3,3′,5,5′-tetramethylbenzidine (TMB) molecules into SERS-active ox-TMB. Ultrasonic-assisted synthesis ensures uniform and dense loading of AgNPs within MOF-919(Fe–Cu), thereby enhancing SERS activity. A sensitive and selective method for SERS detection of L-DOPA was developed. The catechol oxidase-like activity of MOF-919(Fe–Cu) provides ideal selectivity and anti-interference to L-DOPA, while the cascade catalytic system transforms weak SERS signals of L-DOPA into amplified SERS signals of ox-TMB. The mechanism of dual enzyme-mimicking activity was further discussed. The detection process was optimized to achieve high sensitivity towards L-DOPA with a linear range 0.5–100 μmol/L and low limit of detection (LOD) of 0.16 μmol/L. Furthermore, it has been applied in serum sample of Parkinson's patients, demonstrating excellent recovery and low relative error compared to HPLC-UV. This approach offers an economical, efficient and accurate strategy for the detection of L-DOPA and provides valuable insights for the integration of selective multifunctional nanozyme and sensitive SERS detection method.
研究领域:
生物化学
·
纳米医学
·
分析化学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
SENSORS AND ACTUATORS B-CHEMICAL
·
2021
·
IF 7.46
Lili Kong,Jie Chen,Meizhen Huang
In this paper, we have developed a graphene oxide/Au@Ag nanobones membrane (GO/Au@Ag NBs membrane) for simultaneous enrichment and SERS detection of colorants in beverages. Raman enhancement effect of Au@Ag nanobones (NBs) and enrichment capability of graphene oxide (GO) are contributed to the high sensitivity of GO/Au@Ag NBs membrane. Microporous membrane provides a support template for uniformly loading high-density GO/Au@Ag NBs. When beverage flow through the portable filtration unit with GO/Au@Ag NBs membrane, colorant molecules could be efficiently enriched. The prepared GO/Au@Ag NBs membrane exhibits an excellent sensitivity with a LOD of Rhodamine 6 G at 1.12 × 10 −9 mol/L, and has good performances of uniformity (with an RSD of 7.87 %), repeatability (with an RSD of 10.44 %), time stability (stored up to 60 days). Six types of colorants were sensitively detected combined with GO/Au@Ag NBs membranes, portable filtration unit and self-development portable Raman system. The lowest distinguished amounts of molecular accumulation are well below the maximum usage limits and the limits of visual recognition. Support vector machine model was established to identify the types of colorants, including colorants with coincident Raman peaks or similar visual colors, with an average accuracy of 94.8 %. In addition, GO/Au@Ag NBs membranes were used to enrich and detect colorant additives in commercial beverages, brilliant blue in energy beverage and carmine in bayberry wine were successfully detected. These results indicate GO/Au@Ag NBs membranes combined with a portable filtration unit can effectively enrich and rapidly detect colorants in beverages, and has great potential in the field of on-site and sensitive food safety detection.
研究领域:
分析化学
·
食品安全检测
·
纳米材料科学
✓ 已验证
产品关联
DOI
高影响因子
RSC Advances
·
2017
·Vol. 7
·期 58
·36201-36207
·
IF 3.108
Lingzhi Wang,Yin Xu,Xianjun Tan,Sen Tapas,Jinlong Zhang
A sensitive and selective SERS sensor with easy and excellent recyclability is highly demanded because of its great potential application in complex detection environments. Here, using methylene blue (MB) as a model target, a semiconductor-based SERS substrate composed of a MoO3 nanorod core and a uniform molecule-imprinting polymethacrylic acid shell (MIP) with a thickness of 4 nm was designed and fabricated (MoO3@MIP) to achieve selective detection. The key to the successful coating of the ultrathin uniform MIP shell lies in the pretreatment of a MoO3 core with nitric acid, providing sufficient surficial hydroxyls for the anchoring of a polymer precursor. The molecule-imprinted voids for MB were formed simply via light irradiation as a result of photocatalytic degradation by a MoO3 semiconductor. This core–shell MIP composite shows a high SERS selectivity towards low-level MB in a mixed MB/CV solution. The enhanced factor (EF) is high, at 1.6 × 104. More importantly, the selective detection allows the further photocatalytic recycling of MoO3@MIP in an “aim-and-shoot” way, which well preserves the detection selectivity and sensitivity towards MB at least for 4 cycles. Based on decreased sensitivity with the increasing shell thickness (10–24 nm), a MIP-gating charge transfer mechanism is proposed to demonstrate the high EF instead of the molecule-enrichment effect. This “aim-and-shoot” strategy is expected to push forward the prosperous application of selective SERS for trace detection in versatile environments.
研究领域:
分析化学
·
环境科学
·
材料科学
✓ 已验证
产品关联
DOI
高影响因子
RSC Advances
·
2021
·Vol. 11
·期 59
·37443-37448
·
IF 3.361
Huiting Wang,Hairan Zhang,Ling Zhang,Shibo Zhao,Yaxian Chen,Yu Wan,Qian Zhang,Lixin Xia
An ionic liquid (IL)-based liposome was utilized as a substrate to construct a SERS platform. The isotropy of the IL outer surface together with its ion-exchange property led to the array-like growth of Au nanoparticles (NPs), generating hot-spots and resulting in anionic probes being present on the hot-spot regions. The simultaneous strategy of enrichment and localization endowed the platform with ability to detect trace amounts of anionic probes.
研究领域:
分析化学
·
纳米技术
·
生物医学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF FOOD AND DRUG ANALYSIS
·
2022
·
IF 6.157
Wenwen Chen,Qiang Chen,Wei Zhang,De Zhang,Zhi Yu,Ying Song,Xiubing Zhang,Dejiang Ni,Pei Liang
The problem of aflatoxin contamination emerged gradually in the field of food safety. Surface-enhanced Raman spectroscopy (SERS) is an ultra-sensitive and non-destructive spectroscopy technology with extensive application prospects in the detection field. In this paper, with the detection of AFB1 as the target, Au@Ag NPs substrate with uniform morphology and strong SERS effect was prepared. Furthermore, the intermediates formed by hydrogen bonding between AFB1 and melamine facilitate the binding of toxin molecules to the substrate. Moreover, the AFB1-melamine-Au@Ag NPs detection system was established by optimizing the melamine dosage, and the limit of detection can reach 10 −8 mol/L (M). In this method, AFB1 (concentration range of 10 −4 M – 10 −7 M) in tea oil, the Raman signal intensity of AFB1 shows an excellent linear, logarithmic relationship, and the correlation coefficient is 0.9685. Therefore, this work has achieved simple, sensitive, and stable AFB1 detection and has broad application potential in food safety detection.
研究领域:
分析化学
·
食品科学
·
毒理学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Materials Today Communications
·
2023
·
IF 3.8
Ran Feng,Jiazhi Meng,Hualei Yuan,Xu Zhang,Chunlang Gao,Chaogang Ban,Yizhong Guo,Kaiwen Wang
Cancers, Down’s syndrome, Alzheimer’s and other diseases of gene mutation always occur with anomalous changes of DNA nucleic acid base. Therefore, the development of highly sensitive and reproducible nucleic acid sensors that based upon surface enhanced Raman scattering (SERS) is of immense interest for clinical medical analysis and diagnosis. Herein, a rationally designed core-shell assembly of Au nanoparticle wrapped with Au doped Bi 5 O 7 Br nanotube with eliminated fluorescent background and notable chemical enhancement effect was exploited and served as a SERS sensor for detection of adenine. Especially, we found the fluorescent background was remarkably suppressed in Raman spectra by introducing Au element into Bi 5 O 7 Br. The sensor exhibited a maximum SERS enhancement factor of up to 5.45 × 10 7 and a detection limit as low as 10 −11 M after constructing Au nanoparticle/Au atom doped Bi 5 O 7 Br heterojunction . More importantly, good reproducibility and long term stability under work condition were achieved. To gain in-depth understanding into chemical mechanism (CM) of the Raman signal enhancement, density functional calculations (DFTs) were combined with atom-specific model derived via aberration corrected transmission electron microscope (AC-TEM) to demonstrate the enhanced charge transfer (CT) and substrate-adsorbate adsorption. The doping and coupling strategy holds the potential to fabricate high signal-to-noise ratio SERS sensors for other molecule detection.
研究领域:
生物医学工程
·
分子生物学
·
分析化学
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF FOOD COMPOSITION AND ANALYSIS
·
2023
·
IF 4.3
Baihui Wang,Huan Jiang,Ruyi Tang,Yaoyu Tan,Xuemin Xia,Xia Zhang
The activity of nanozymes is dependent on their surface for catalysis, and bioconjugation or adsorption of DNA aptamers will promote their activity. This paper aims to develop a novel aptamer sensor, for rapid, sensitive and specific detection of histamine. The design of the aptamer biosensor is based on the adsorption of histamine aptamers onto the surface of Au NPs by bioconjugation, which promotes the peroxidase activity of the nanozymes. Since histamine is strongly selective and specific for histamine aptamers, the histamine aptamer can be detached from the surface of Au NPs and bound to histamine, during which the catalytic activity of the nanozymes falls back due to the detachment of the histamine aptamer, which can be quantitative analysis by the TMB-H 2 O 2 system. The decrease in enzyme catalytic activity became larger with increasing histamine concentration, with a good linear correlation. Finally, the histamine aptamer biosensor was constructed, which has the advantages of ultrasensitive, high-accuracy, and wide linear range. The linear range and detection limit are 10 −11 ∼10 −3 M and 1.22 × 10 −12 M, respectively. With reference to this aptamer sensor design, this approach can also be extended to other schemes where the aptamer is combined with Au NPs as a way to detect the corresponding molecules.
研究领域:
生物化学
·
分析化学
·
纳米技术
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）