FOOD CHEMISTRY
·
2025
·
IF 9.8
Xiaomu Shan,Jie Pan,Xuejian Du,Jian Shi,Zhuofan Wei,Yuanze Xu,Shouzhen Jiang
The excellent performance of surface-enhanced Raman spectroscopy (SERS) is closely related to the intensity, density and uniformity of hotspots. In this study, we introduce a PET/Au NPs@COF Raman substrate featuring three-dimensional hotspots. The spacing between each layer of gold nanoparticles (NPs) is precisely controlled by adjusting the thickness of the COF via the interfacial synthesis technique, causing the strong coupling between gold particles across the layers. The porosity of the COF enables the substrate to adsorb numerous analyte molecules into the large-area uniform hotspots. Through simulations and adsorption detection on the substrate, Raman testing further demonstrated that the substrate with double-layer Au NPs@COF exhibited the most favorable SERS performance. Additionally, the substrate allows for selective detection based on the particle size of the target molecule. The flexibility of the substrate enables it to conform to irregular surfaces, effectively capturing analytes from a variety of real samples.
研究领域:
材料科学
·
分析化学
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产品关联
DOI
PubMed
高影响因子
MICROCHIMICA ACTA
·
2024
·Vol. 191
·期 2
·1-11
·
IF 5.3
Li Kaiwei,Jiang Han,Wang Liying,Wang Rui,Zhang Xuewei,Yang Libin,Jiang Xin,Song Wei,Zhao Bing
Semiconductor materials have become a competitive candidate for surface-enhanced Raman scattering (SERS) substrate. However, powdered semiconductors are difficult to execute a fast in situ detection for trace analytes. Here, we developed a new flexible semiconductor SERS substrate by in situ densely growing anatase TiO 2 nanoparticles on the surface of cotton fabric through a filtration-hydrothermal method, in which TiO 2 exhibits excellent controllability in size and distribution by regulating the ratio of water to alcohol in synthesis and the number of filtration-hydrothermal repetitive cycle. Cotton fabric/TiO 2 (Cot/TiO 2 ) substrate exhibits a high SERS activity and excellent spectral repeatability. The developed substrate has an ultra-high stability that can withstand long-term preservation; it can even resist the corrosions of strong acid and alkali, as well as high temperature up to 100 °C and low temperature down to − 20 °C. The flexible substrate can be used to carry out a rapid in situ detection for quinolone antibiotic (enrofloxacin and enoxacin) residues on the fish body surface by using a simple swabbing method, with high quantitative detection potential (up to an order of magnitude of 10 −7 M), and even for the simultaneous detection of both drug residues. The flexible substrate also exhibits an excellent recyclability up to 6 recycles in the actual SERS detection. Graphical Abstract
研究领域:
材料科学
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分析化学
·
环境科学
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产品关联
DOI
PubMed
高影响因子
Analytical Methods
·
2024
·
IF 2.7
Wenxia Xue,Jihong Fu,Yaxue Zhang,Shuxian Ren,Guoqi Liu
Surface-enhanced Raman scattering (SERS) enables pesticide residue monitoring to become facile and efficient. In this study, a core–shell structured gold nanoparticles@ZnCo metal–organic framework (AuNPs@ZnCo-MOF) SERS substrate was designed and successfully synthesized for efficient and selective detection of thiram. The bimetallic ZnCo-MOF shell can not only enrich the targeted molecules in the electromagnetic field because of its excellent absorptive capacity, but also act as a stabilized matrix for protecting the AuNPs from aggregation. The AuNPs@ZnCo-MOFs exhibited a high enhancement factor (EF) of 3.51 × 106 and a low detection limit of 1 × 10−7 mol L−1. Besides, the substrate material showed exceptional stability for up to 28 days at room temperature. The AuNPs@ZnCo-MOFs were used to detect thiram which displayed wide linearity (1 × 10−7 to 1 × 10−4 mol L−1) and high recoveries (83.45–99.61%). Moreover, the AuNPs@ZnCo-MOF SERS substrate exhibited excellent anti-interference ability and size selectivity for the target molecules. These indicate that the AuNPs@ZnCo-MOF substrate has great potential for the detection of thiram residues in practical applications.
研究领域:
分析化学
·
材料科学
·
环境科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
RSC Advances
·
2017
·Vol. 7
·期 25
·14959-14965
·
IF 3.108
Xinxin Yu,Ranran Cai,Yuqing Song,Qiang Gao,Nan Pan,Mingzai Wu,Xiaoping Wang
During the past decades, researchers have made great efforts towards an ideal surface enhanced Raman spectroscopy (SERS) substrate. Here a smart SERS-active flexible substrate was designed and its performance was studied. The substrate is constructed from graphene and TiO2, and could be divided into two functional layers. Graphene provides a flat hot surface for Raman enhancement, which could be ascribed to chemical enhancement. The TiO2 layer is an effective photocatalyst, which could induce photocatalytic decomposition of adsorbed molecules under UV irradiation. Notably, the substrate was realized by a one-step transfer method, followed by annealing. In the synthesis process, a flexible TiO2 layer was produced by spin-coating on the CVD graphene and was used as a support in the transfer process of graphene instead of PMMA, which could exclude contamination and avoid degradation of the Raman enhancement performance. Combining detection with degradation of trace amounts of analyte, the versatility of the SERS substrate is greatly enhanced and could be adapted to fit a wide range of sensing and photocatalytic applications.
研究领域:
材料科学
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分析化学
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环境科学
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产品关联
DOI
高影响因子
MACROMOLECULAR RESEARCH
·
2013
·Vol. 21
·期 3
·306-310
·
IF 1.639
Zhang Wen-Yi,Xiao Xin-Ze,Lv Chao,Zhao Jia,Wang Gong,Gu Xuan,Zhang Ran,Xu Bin-Bin,Zhang Dan-Dan,Li Ai-Wu,Zhang Yong-Lai,Sun Hong-Bo
Reported here is the fabrication of photopolymer hierarchical micronanostructures through a combinative process of electrospinning and subsequent photolithography. Electrospun SU-8 (epoxy-based negative photoresist) nanofiber films have been patterned into gratings with periods of 100, 200, 300, and 400 μm, respectively. Deposition of a silver nanolayer on these interlaced nanofiber films would lead to the formation of various plasmonic nanostructures, and therefore, giving rise to abundant surface-enhanced Raman scattering (SERS) “hot spots”. In the detection of Rhodamine 6G (R6G), probing molecule, the resultant SERS substrates show both high sensitivity and good reproducibility. The SERS enhancement factor could reach as high as ∼10 8 , indicating high efficiency. The fabrication of patterned, highly efficient SERS substrates may hold a great promise for the integration of SERS substrates in various microdevices such as microfluidic chips.
研究领域:
材料科学
·
光学
·
分析化学
✓ 已验证
产品关联
DOI
高影响因子
FOOD RESEARCH INTERNATIONAL
·
2022
·
IF 7.425
Yaodi Zhu,Weijia Liu,Shijie Liu,Miaoyun Li,Lijun Zhao,Lina Xu,Na Wang,Gaiming Zhao,Qiuying Yu
In this study, we developed a novel and sensitive AgNPs self-assembled solid-phase (AgNPs-SASP) SERS substrate platform using seed-mediated and liquid interface self-assembly methods and applied the platform for the detection of three bacterial spores. Multivariate statistical analysis (HCA and LDA) were employed for identification and categorization of the obtained data. The results illustrated that AgNPs-SASP exhibited high reproducibility and Raman enhancement effect (1.43 × 10 4 ). The Raman shift bands of the three bacterial spores ranged from 400 to 1800 cm −1 demonstrating the difference in reigon and intensity. And the intensities of their Ca 2+ -DPA Raman bands are significantly different. HCA results revealed that the spectra for the three bacterial spores were statistically different while LDA completely differentiated the spectra for the three bacterial spores with 100 % sensitivity and specificity. Overall, the novel SERS platform based on AgNPs-SASP provides an effective tool for food safety risk control and detection.
研究领域:
食品科学
·
分析化学
·
生物技术
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产品关联
DOI
PubMed
高影响因子
SENSORS AND ACTUATORS B-CHEMICAL
·
2025
·
IF 7.7
XianWei Wang,Yue Zhai,Yuanhui Chen,Wei Zhang,Pei Liang,Qiangqiang Zhu,Hong Zhang,Juan Kang,Le Wang
s The development of a highly sensitive and reliable surface-enhanced Raman scattering (SERS) substrate is crucial for overcoming the limitations in its practical applications. Herein, a novel 3D waffle-like SERS substrate with high activity is constructed for detecting trace amounts of myricetin in complex analytes extracted from green tea. The substrate is achieved through a layered ternary film structure, where ordered poly (methyl methacrylate) opal photonic crystals (PMMA OPCs) serving as a 3D hot spots template and enhancing the performance of CsPbBr 3 film that facilitates efficient charge transport, and an Au film covered over the CsPbBr 3 film modulating the vibronic coupling and providing plasmonic hot spots. The PMMA-CsPbBr 3 -Au substrate exhibits a low detection limit of 10 −10 M with an 8.9 × 10 7 enhancement factor, signal repeatability and stability for R6G molecules. Furthermore, the SERS detection of myricetin content in Longjing green tea from different years is carried out, and the results show a good linear positive correlation with storage years (R 2 =98.2 %), demonstrating the potential application of 3D substrate for sensitive and reproducible SERS.
研究领域:
材料科学
·
分析化学
✓ 已验证
产品关联
DOI
高影响因子
FOOD CHEMISTRY
·
2025
·
IF 9.8
Tianxing Fang,Qingyi Wei,Erwen Wu,Hongbin Pu
Malachite green (MG), with teratogenic and reproductive toxicity, is widely misused as an antimicrobial agent, posing a serious threat to animal and human health. Therefore, this study developed a novel recyclable Surface-enhanced Raman scattering (SERS) hydrogel substrate, TiO 2 /MXene/PAA-PAM@AuNPs (TMPA), by forming a dual hydrogen-bond network using a PAA-PAM hydrogel matrix with TiO 2 /MXene and embedding AuNPs, for detecting MG residues in aquatic products. This hydrogel exhibits high sensitivity, with a detection limit for MG of 8.13 × 10 −6 mg/L. Additionally, it can completely degrade surface-adsorbed MG within 60 min under light irradiation, achieving self-cleaning and enabling reuse for more than seven cycles, and can be stored for over 50 days while maintaining its SERS activity due to the support and preservation provided by the hydrogel network. Additionally, this substrate can rapidly detect MG residues on or within fish, offering a new strategy for monitoring MG residues in aquatic products.
研究领域:
食品安全
·
分析化学
·
环境科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
LANGMUIR
·
2022
·
IF 4.331
Rong Chang,Tao Wang,Qian Liu,Jun Tang,Dongling Wu
Flexible surface-enhanced Raman scattering (SERS) substrates have become one of the research hot spots due to the facile sampling by swabbing or wrapping on rough surfaces and the sensitive and nondestructive detection of contaminants. In this work, we proposed a simple and fast in situ reduction method to prepare Ag nanoparticles (Ag NPs) composited agar hydrogel (Ag NPs@Agar) flexible SERS substrate. Owing to the three-dimensional (3D) structure, good hydrophilicity and adsorption of the agar hydrogel, Ag NPs were grown uniformly in the 3D cross-linked structure. The distribution density of Ag NPs was further increased by the volume shrinkage when the hydrogel was dried in air. This high density and uniformly distribution of Ag NPs produced a large number of highly active SERS regions. In addition, the sensitivity of Ag NPs@Agar was further improved with the assistance of hydrophilic agar gel, which can trap the probe molecules into highly active SERS areas. The SERS results showed that the substrate can be used to detect dye molecules (rhodamine 6G), the minimum detectable concentration was 10–15 M, the relative standard deviation tested at 18 different positions was only 7.58%, and the intensity of the characteristic peak at 611 cm–1 decreased only about 10% after 49 days of storage, demonstrating the superior stability. Moreover, the Ag NPs@Agar substrate also could successfully achieve the micro-trace detection of melamine and sodium penicillin G in Xinjiang specialty camel milk powder. The above available results show that the prepared flexible Ag NPs@Agar SERS substrates possess potentials for the illegal additives and antibiotics in food safety analysis.
研究领域:
材料科学
·
分析化学
·
食品安全检测
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF ALLOYS AND COMPOUNDS
·
2022
·
IF 6.371
Jiaxi Sui,Dongdong Liu,Chunyu Wang,Lijuan Wang,Bo Zhong,Yuanyuan Ma
Non-metallic Surface-Enhanced Raman Scattering (SERS) substrate materials with unique structures are considered as promising candidates for detection of dyes in the environment. In this work, a sea urchin-like K 2 Ti 8 O 17 (KTO) nanomaterial was prepared by a facile and efficient hydrothermal method . The enhancement factors of the sea urchin-like KTO for crystal violet and methylene blue are 3.8 × 10 5 and 2.45 × 10 5 respectively, and the minimum detection limits of both can reach 10 −8 M, which means the sea urchin-like KTO a promising non-metallic SERS substrate for detecting dyes in the environment. The excellent SERS performance of the sea urchin KTO was attributed to the excellent charge transfer and probe adsorption capability of KTO by energy band and zeta potential analysis. Finally, the excellent application potential of the sea urchin KTO was verified by simulating a practical use scenario.
研究领域:
材料科学
·
环境科学
✓ 已验证
产品关联
DOI
高影响因子
Plasmonics
·
2025
·
IF 4.3
Chen Kun,Ma Chaoqun,Chen Guoqing,Yang Taiqun,Gao Hui,Li Lei,Hu Anqi,Cao Jun,Zheng Chenkai,Ma Longyao,Chen Zehao
The detection of pefloxacin (PEF) in milk is of significant importance for food safety. Traditional methods for detecting PEF often rely on techniques such as high-performance liquid chromatography (HPLC), which are complex and time-consuming. This article introduces a surface-enhanced Raman scattering (SERS) substrate based on a composite of covalent organic frameworks (COFs) and silver nanoparticles (AgNPs) for the rapid detection of PEF in milk. After testing PEF in both water and milk, the detection limits were calculated to be 6.31 μg/L for water and 82 μg/L for milk, with correlation coefficients of 0.991 and 0.998, respectively. Furthermore, the average recovery rate of PEF in milk ranged from 96.25% to 106.17%, with a relative standard deviation (RSD) of 4.32% to 8.88%. This work offers a simple and rapid method for detecting PEF in milk. Graphical
研究领域:
食品安全
·
分析化学
·
药物残留检测
✓ 已验证
产品关联
DOI
高影响因子
MICROCHEMICAL JOURNAL
·
2024
·
IF 4.9
Jie Shi,Xiaoqing Huang,Jiangtao Xu
Island-shaped Ag nanoparticles are prepared under the support platform of quartz fabric by a simple chemical deposition method. The prepared flexible SERS substrate in this study demonstrates highly sensitive, excellent signal reproducibility and stability. The enhancement ability can be adjusted by varying concentration of Ag + during synthesizing process, which would lead to the variation of size and gaps of Ag nanoparticles , thus affecting the LSPR effect. Moreover, the prepared SERS substrate shows great practical potential in rapid detection of contaminated fruit with different sampling method.
研究领域:
材料科学
·
分析化学
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）