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SLP-2
CARBOHYDRATE POLYMERS · 2022 · IF 10.723

A novel Stauntonia leucantha fruits arabinogalactan: isolation and structural characterization

Hui Li,Tao Gao,Zhonghao Zhang,Jiangping Lei,Junchao Hu,Zizhong Tang,Shiling Feng,Chunbang Ding,Tao Chen,Yanger Chen,Shu Yuan,Ming Yuan

Polysaccharides were the key ingredients of many herbal medicines, and were responsible for multiple pharmacological activities. In this study, a novel polysaccharide fraction, named SLP-2, was isolated from Stauntonia leucantha fruits, and purified by DEAE-52 and Sephadex G-100 column chromatography . Furthermore, SLP-2 was identified by congo red, methylation , partial acid hydrolysis and NMR . The results indicated that the backbone of SLP-2 was composed of →4)-β-D-Gal p -(1 → 4)-β-D-Gal p -(1→ substituted at C-6 with 1,5-linked arabinan . SLP-2 had good anti-oxidation ability in vitro. Surprisingly, we found that reduction of carboxyl groups and methylation of hydroxyl groups enhanced the ability to scavenge 2,2′-azinobis (3-ethylbenzothiazoline-6-sulfonic acid) diammonium salt (ABTS) radicals and inhibit lipid peroxidation , and weakened the activity to scavenge 1,1-diphenyl-2-picrylhydrazyl (DPPH) radicals and reduce ferric iron.

研究领域: 药理学 · 化学 · 植物科学 · 生物化学
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