EUROPEAN POLYMER JOURNAL
·
2023
·
IF 6
Lu Wang,Xin Gang,Yu Xiao,Yi Ren,Jianhong Wang,Baolong Niu,Wenfeng Li
In this study, CMCS-CuO nanoparticles were added to the SA matrix by blending method to prepare SA/CMCS-CuO composite microspheres. The chemical structure and morphology of the composite beads were characterized. The results showed that there was a certain molecular interaction between CMCS-CuO NPs and SA matrix. The swelling experiment showed that with the increase of the mass of CMCS-CuO NPs, the maximum swelling ratio of gel microspheres decreased from 49.83% to 38.2%, and the time to reach the maximum swelling ratio also increased from 8 h to 11 h. Cytotoxicity test, hemolysis test, and cell migration test showed that the composite microspheres had good biocompatibility. Curcumin was added to the composite bead matrix by the blending method, and curcumin-loaded SA/CMCS-CuO composite beads were prepared by the crosslinking method. In vitro release experiments showed that SA/CMCS-CuO composite microspheres had good pH sensitivity, and the addition of CMCS-CuO NPs prolonged the in vitro release time of cur. It has certain application potential in the field of drug release.
研究领域:
材料科学
·
药学
✓ 已验证
产品关联
DOI
高影响因子
LANGMUIR
·
2024
·
IF 3.7
Xiaonan Li,Jing Li,Xiyu Jia,Nian Liu,Xinrui Gao,Zuoqin Zhou,Wei Yang,Bing Wei,Zheng Yang,Suhua Fan,Hai Wu,Hui Zhang
The magnetic composite gel bead (Fe3O4–C@SA GB) adsorbent was prepared by sodium alginate (SA) crosslinking with pitaya peel-derived porous carbons (PPDPCs) and magnetic iron oxide nanoparticles (Fe3O4 NPs). The adsorption effects of Fe3O4–C@SA GBs on heavy metal ions (HMIs) and 17 β-estradiol (E2) in water are evaluated by classical kinetic models and isotherm models. The pseudo-second-order kinetic model shows that Fe3O4–C@SA GBs have maximum adsorption capacities of 9.62, 7.50, and 13.61 mg/g for Cu (II), Cd (II), and Pb (II), respectively. Meanwhile, the highest adsorption performance of the synthesized gel beads to E2 is of ca. 276.3 mg/g. In addition, the Fe3O4–C@SA GBs can still maintain a high level of adsorption efficiency after five adsorption cycles, displaying economic efficiency and reusability. Hence, this work provides useful insights into the efficient adsorption elimination of pollutants in sewage and the corresponding adsorption mechanisms.
研究领域:
环境科学
·
材料科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
FIBERS AND POLYMERS
·
2025
·
IF 2.3
Bin Guoan,Song Jiali,Liu Yichen,Hao Longyun
In this research, an amphiphilic sodium alginate (SSA) was prepared by grafting styrene (St) onto sodium alginate (SA) to serve as a dispersant for preparing copper phthalocyanine (CuPc) pigment dispersion (SSA-CuPc). The results indicated that SSA exhibited optimal dispersibility for CuPc at 20% dosage. Compared to SA, the SSA-CuPc particle size was reduced by 63.61%, zeta potential from − 15.30 mV to − 29.16 mV. FT-IR, XPS, and TG analyses confirmed the effective binding of SSA on CuPc surface. The SSA-CuPc dispersion displayed excellent stability and compatibility in SA solution, with stability R value decreased to 5.66%. The SSA-CuPc was incorporated into SA spinning solution to fabricate dope-dyed SA fibers by wet spinning. Rheological tests revealed enhanced compatibility between SSA-CuPc and SA matrix, favorable for wet-spinning processing. Mechanical tests indicated a 35.33% improvement in elongation at break for dope-dyed SA fibers compared to original SA fibers. SEM, FT-IR, and TG analyses further verified the uniform distribution and stable existence of SSA-CuPc in SA fibers.
研究领域:
高分子科学
·
材料工程
·
纺织工程
·
胶体与界面科学
✓ 已验证
产品关联
DOI
高影响因子
DIAMOND AND RELATED MATERIALS
·
2024
·
IF 4.3
Yu Li,Yuxin Xu,Jiayu Zhu,Xianghui Meng,Shuang Ai,Meiling Zhang,Fan Yang,Huabing Yin,Kui Cheng
Heavy metal contamination, particularly from Pb(II), poses severe environmental and health risks due to its toxicity and persistence in ecosystems. This study presents an innovative and sustainable adsorbent composed of nitrogen doped carbon quantum dots (NCDs), derived from sodium alginate and immobilized on a sodium alginate hydrogel (HL-NCDs), for the efficient extraction of Pb(II) from water. The experimental results indicate that Pb N and Pb C interactions, particularly involving the N H moieties within the carbon quantum dots, are the predominant mechanisms facilitating Pb(II) removal, as confirmed by density functional theory (DFT) calculations. These interactions are substantiated by thermodynamic analyses and charge distribution studies, which highlight the enhanced affinity of HL-NCDs towards Pb(II) ions. The novel HL-NCDs composite material not only demonstrates excellent Pb(II) adsorption efficiency but also suggests broad applicability in water treatment technologies, marking a significant advancement in the use of biomass-derived materials for environmental remediation.
研究领域:
环境科学
·
材料科学
✓ 已验证
产品关联
DOI
高影响因子
THERIOGENOLOGY
·
2018
·
IF 2.136
Gang Liu,Shubin Li,Haihan Yuan,Mengrui Hao,Wurihan,Zhizhong Yun,Jie Zhao,Yuzhen Ma,Yanfeng Dai
The survival rate of vitrified-thawed ovarian tissues after autotransplantation still needs to be improved. Therefore finding an ideal cryoprectant to reduce the damage to ovaries that caused by vitrification will pave the way for application of ovary cryopreservation on clinics. Experiments were conducted to investigate the effect of sodium alginate in cryoprotectant solution on mouse ovaries during the vitrification process. The ovaries obtained from 6-weeks old CD1 were assigned into six groups from A to F. Group A without treatment was used as the normal control. Group B cryopreserved with the basic cryoprotectant solution containing 15% each Me 2 SO and EG was used as the experimental control. Groups C, D, E, and F cryopreserved with the basic cryoprotectant solution supplemented with 0.05%, 0.10%, 0.15%, and 0.20% of sodium alginate, respectively, were assigned for the experimental groups. The in vitro analyses showed that the developmental capability of the oocytes isolated from vitrified-thawed ovaries significantly increased with increasing concentration of sodium alginate in the cryoprotectant solution (groups: A = 70 ± 2; B = 43 ± 2; C = 48 ± 3; D = 53 ± 3; E = 60 ± 3; B < C < D < A, P < 0.05), and reached its highest level in group E with 0.15% of sodium alginate (P < 0.05). The lowest developmental capability of all groups was group F (41 ± 1%)(P < 0.05) with 0.20% of sodium alginate. The similar results were obtained by the autotransplantation in vivo . These finding demonstrated that sodium alginate can significantly reduce the damage to ovaries by vitrification.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2023
·
IF 8.2
Hongkai Zhang,Xiaofang Bian,Shunjing Luo,Chengmei Liu,Xiuting Hu
The effect of sodium alginate (SA) on the yogurt stability and the related mechanisms were investigated. It was found that low-concentration SA (≤0.2 %) increased the yogurt stability, while high-concentration SA (≥0.3 %) decreased the yogurt stability. Sodium alginate increased the viscosity and viscoelasticity of yogurt and this effect was positively correlated with its concentration, suggesting that SA worked as the thickening agent in yogurt. However, addition of ≥0.3 % SA damaged the yogurt gel. These results suggested that interaction between milk protein and SA might play an important role in the yogurt stability besides the thickening effect. Addition of ≤0.2 % SA did not change the particle size of casein micelles. However, addition of ≥0.3 % SA induced aggregation of casein micelles and increased the size. And the aggregated casein micelles precipitated after 3 h storage. Isothermal titration calorimetry analysis showed that casein micelles and SA were thermodynamically incompatible. These results suggested that the interaction between casein micelles and SA induced aggregation and precipitation of casein micelles, which was critical in the destabilization of yogurt. In conclusion, the effect of SA on the yogurt stability was dependent on the thickening effect and the interaction between casein micelles and SA.
研究领域:
食品科学
·
化学
✓ 已验证
DOI
PubMed
高影响因子
Journal of Macromolecular Science Part B-Physics
·
2023
·
IF 1.4
Wen-jie Tang,Jin-xin Zhang,Liang Liu,Lu-yao Zhao,Liu Wang,Chang Shi,Yang Liu,Mei-ling Wen
Calcium alginate gel microspheres exhibiting pH response release characteristics were prepared, and utilizing Bovine serum albumin (BSA) to evaluate drug release performance. Hydrogels composed of gelatin (GL) and sodium alginate oxide (NALO), with varying ratios (7:3; 4:1; 3:2) were prepared by controlling their composition. Scanning electron microscopy (SEM) and a microplate reader (ELIASA) were used to characterize the microspheres’ microstructure and in vitro BSA release behavior, respectively. The results demonstrated that, under acidic conditions, the BSA release was slower than in neutral conditions. The hydrogels’ physical and chemical properties were analyzed using optical microscopy, Fourier transform infrared spectroscopy (FTIR), swelling experiments and mechanical testing of the hydrogels and microsphere loaded hydrogels. The results showed that a GL to NALO ratio of 7:3 increased the swelling degree, while a 4:1 ratio optimized the mechanical characteristics. The study concluded that the microsphere-loaded hydrogels exhibited significant potential for human drug delivery applications.
研究领域:
生物医学工程
·
药学
·
材料科学
·
高分子科学
✓ 已验证
DOI
高影响因子
DESALINATION
·
2026
·
IF 9.9
Bashir Hashim Bashir,Gideon Muradi,Baoquan Zhang
Pervaporation desalination is a promising technology for treating hypersaline water, yet its broader application is constrained by the low water flux of conventional membranes. Herein, novel sodium alginate-polyamide (SA-PA) composite membranes were fabricated on hydrolyzed polyacrylonitrile (hPAN) ultrafiltration membranes via interfacial polymerization (IP) using a sequential deposition and one-step co-deposition method for pervaporation desalination. Comprehensive characterization revealed that the SA layer enhances hydrophilicity while the PA network ensures structural integrity. The sequentially fabricated s-SA-PA 1.0/hPAN membrane, with a well-defined layer structure, achieved a flux of 34.21 kg m −2 h −1 with 99.99% rejection (3.5 wt% NaCl, 70 °C), owing to its distinct hydrophilic SA layer and dense PA-selective layer. In the one-step co-deposition method, SA binds preferentially with piperazine (PIP) and tiles the water-hexane interface, thereby reducing the diffusion rate of PIP and restricting its diffusion pathways towards the hexane phase, resulting in a nanoscale structure with a thin, selective layer (~75–130 nm). This modulation of IP kinetics resulted in the one-step co-deposited c-SA-PA 2.0/hPAN membrane, which exhibited a superior flux (59.32 kg m −2 h −1 ) with a maintained rejection of 99.9%. Systematic evaluation of operational parameters and long-term testing confirmed the stability of these SA-PA composite membranes, demonstrating a sustainable strategy for high-performance desalination through bio-based polymers and scalable fabrication. This work establishes that precisely engineered nanoscale architectures in polymer composites can simultaneously enhance multiple membrane performance metrics, providing new design principles for advanced desalination materials.
✓ 已验证
DOI
高影响因子
Nanomaterials
·
2024
·
IF 4.4
Xiaohang Lin,Yuzhu Xiong,Fuping Dong
Environmental pollution of phosphorus is becoming increasingly concerning, and phosphate removal from water has become an important issue for controlling eutrophication. Modified metal–organic framework (MOF) materials, such as UiO-66-NH 2 , are promising adsorbents for phosphate removal in aquatic environments due to their high specific surface area, high porosity, and open active metal sites. In this study, a millimeter-sized alginate/UiO-66-NH 2 composite hydrogel modified by polyethyleneimine (UiO-66-NH 2 /SA@PEI) was prepared. The entrapping of UiO-66-NH 2 in the alginate microspheres and its modification with PEI facilitate easy separation in addition to enhanced adsorption properties. The materials were characterized by SEM, FTIR, XRD, and BET. Static, dynamic, and cyclic adsorption experiments were conducted under different pH, temperature, adsorbent dosage, and initial concentration conditions to assess the phosphate adsorption ability of UiO-66-NH 2 /SA@PEI. Under optimal conditions of 65 °C and pH = 2, 0.05 g UiO-66-NH 2 /SA@PEI adsorbed 68.75 mg/g, and the adsorption rate remained at 99% after five cycles of UiO-66-NH 2 /SA@PEI. These results suggest that UiO-66-NH 2 /SA@PEI composite materials can be used as an effective adsorbent for phosphate removal from wastewater.
研究领域:
环境科学
·
材料科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION
·
2025
·
IF 3.6
Yongze Liu,Mei Li,Genyuan Li,Lei He,Xiaofeng Ma,Zhaoxiang Zhang,Jun Zhang
The risks associated with wound infections are significant, making a snug-fitting hydrogel dressing an optimal choice for wound management. For it, we employed the self-cross-linking method of oxidized sodium alginate (SCSA), incorporating clarithromycin (Cla) and basic fibroblast growth factor (bFGF) to formulate a rapidly forming, bacteriostatic, and wound-healing hydrogel (SCSA@C/b). Bacteriostatic and cytocompatibility assays demonstrated that SCSA@C/b exhibits exceptional antibacterial activity alongside strong biocompatibility. A fractional infected wound model showed that SCSA@C/b accelerated healing of infected wounds by approximately three days compared to the healing time of the control group, with nearly complete wound recovery. H&E staining and SEM analysis of the healed wound sections revealed significant pro-healing effects. Thus, SCSA@C/b is a promising medicinal hydrogel for encouraging wound healing in contaminated areas.
研究领域:
生物材料学
·
医学工程
·
药理学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
FOOD CHEMISTRY
·
2022
·
IF 9.231
Liming Ge,Zijing Li,Miao Han,Yongjie Wang,Xinying Li,Changdao Mu,Defu Li
Food security is an important global public health issue, which will not only endanger consumers’ life and health, but also cause serious food waste. Herein, antibacterial dialdehyde sodium alginate/ ε -polylysine microspheres (DSA-PL MPs) were developed to effectively prolong the shelf life of fruit. DSA was prepared by periodate oxidation of sodium alginate. Then the PL was conjugated onto DSA backbone via the Schiff’s base reaction to synthesize DSA-PL conjugates, followed by the emulsification and Ca 2+ ions crosslinking to obtain DSA-PL MPs. The results indicate that DSA-PL MPs show smooth spherical particle, relatively narrow size distribution and good dispersity. In vitro degradation rate of DSA-PL MPs is higher in acetate buffer (pH = 5.0) than that in PBS buffer (pH = 7.4), showing acid-sensitive degradation property. Significantly, DSA-PL MPs possess strong broad-spectrum antibacterial activity, which can effectively extend the shelf life of fruit. Overall, DSA-PL MPs possess promising application as antibacterial agents for fruit preservation.
研究领域:
食品科学
·
材料科学
✓ 已验证
DOI
PubMed
高影响因子
JOURNAL OF THE CHINESE CHEMICAL SOCIETY
·
2017
·Vol. 64
·期 2
·231-238
·
IF 0.935
Jie Wu,Zongmei Wu,Xuejiao Sun,Shichao Yuan,Ruling Zhang,Qingliang Lu,Yueqin Yu
Sodium alginate (SA) was combined with poly( N -isopropylacrylamide) (PNIPAAm) to prepare thermosensitive hydrogels through semi-interpenetrating polymer network (semi-IPN) and fully interpenetrating polymer network (full-IPN). The thermosensitive, swelling, mechanical, and thermal properties of pure PNIPAAm, SA/PNIPAAm semi-IPN, and Ca-alginate/PNIPAAm full-IPN hydrogels were investigated. The formation of semi-IPN and full-IPN significantly improved the hydrogels’ swelling capability and mechanical properties without altering their thermosensitivity. 5-Fluorouracil (5-Fu) was selected as a model drug to study the release behaviors of the hydrogels. It was found that in vitro controlled drug release from semi-IPN hydrogels showed an initial release burst, followed by a slower and sustained release, before reaching equilibrium. Full-IPN hydrogels showed slow and sustained release during the whole process. Temperature and pH were found to affect the rate of drug release. Ca-alginate/PNIPAAm full-IPN hydrogels have potential application as drug delivery matrices in controlled drug release.
研究领域:
生物材料
·
药剂学
·
高分子科学
·
组织工程
·
药物递送系统
✓ 已验证
DOI
高影响因子
危险品化学品经营许可证（带存储）