SENSORS
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2019
·Vol. 19
·期 6
·1281
·
IF 3.031
Qihua Sun,Zhaofeng Wu,Haiming Duan,Dianzeng Jia
Triacetone triperoxide (TATP) is a self-made explosive synthesized from the commonly used chemical acetone (C3H6O) and hydrogen peroxide (H2O2). As C3H6O and H2O2are the precursors of TATP, their detection is very important due to the high risk of the presence of TATP. In order to detect the precursors of TATP effectively, hierarchical molybdenum disulfide/reduced graphene oxide (MoS2/RGO) composites were synthesized by a hydrothermal method, using two-dimensional reduced graphene oxide (RGO) as template. The effects of the ratio of RGO to raw materials for the synthesis of MoS2on the morphology, structure, and gas sensing properties of the MoS2/RGO composites were studied. It was found that after optimization, the response to 50 ppm of H2O2vapor was increased from 29.0% to 373.1%, achieving an increase of about 12 times. Meanwhile, all three sensors based on MoS2/RGO composites exhibited excellent anti-interference performance to ozone with strong oxidation. Furthermore, three sensors based on MoS2/RGO composites were fabricated into a simple sensor array, realizing discriminative detection of three target analytes in 14.5 s at room temperature. This work shows that the synergistic effect between two-dimensional RGO and MoS2provides new possibilities for the development of high performance sensors.Keywords:(TATP) precursors;MoS2/RGO composites;sensor arrays;synergistic effect
研究领域:
化学工程
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材料科学
·
传感技术
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产品关联
DOI
PubMed
高影响因子
Nano Select
·
2020
·Vol. 1
·期 4
·419-431
·
IF 0
Guanshun Xie,Xiaorong Lv,Peng Zhang,Bingxin Liu,Li Gao,Junyuan Duan,Bin Ma,Zhaofeng Wu
Triacetone triperoxide (TATP) is widely used in terrorist attacks because of its simple synthesis but hard to be directly detected. Herein, polyphenylene vinylene (PPV) derivative with the vinyl group on the side chain is cross-linked by Au nanoclusters (Au NCs) to construct flexible Schottky sensors to arrange the uncontactless detection of TATP vapor. Experiments and simulations show that Au NCs generate a strong electromagnetic field with collective coupling which can effectively promote the photoinduced electron-hole separation of the PPV and detection sensitivity to TATP. The simple fingerprint patterns can discriminate TATP from 2,4,6-trinitrotoluene (TNT), 2,4-dinitrotoluene (DNT), p-nitrotoluene
(PNT), picric acid (PA), Hexogen (RDX), and tetryl by pattern to recognize inherent kinetics and thermodynamics of interaction between the sensors and specimen. The electron transfers from Au NCs to PPV after the adsorption of TATP molecules as the electronegativity of TATP is smaller than that of Au NCs and which is obvious in electron donating effect. Therefore, Au acts as a hole trap and reduces the hole concentration as well as restricting the carrier transport. However, the oscillator strength of the charge transferred from Au NCs to PPV simulation indicates that the role of Au NCs change from the hole trap to electron trap after adsorption of other explosives. Furthermore, the flexibility and stability of the sensor films are also demonstrated in this paper which is of great significance for the practical application of flexible electronic devices with high performance.
研究领域:
材料科学
·
分析化学
·
电子工程
·
物理化学
✓ 已验证
DOI
ANALYTICAL SCIENCES
·
2023
·Vol. 39
·期 6
·935-943
·
IF 1.6
Wang Jingyu,Cui Yunyi,Lin Ying,He Yi
Abstract A long-standing challenge in colorimetric detection of triacetone triperoxide (TATP) explosive is low sensitivity. We herein developed an iodine-mediated photoinduced auto-inductive tandem chromogenic system to achieve exponential signal amplification. The strategy employs the KI-TATP reaction and photo-induced autocatalytical oxidation of o-phenylenediamine (OPD) that work in tandem. The resulting I 3 − from the KI-TATP reaction oxidizes OPD to yellow 2,3-diaminophenazine (DAP) that is further excited by blue light illumination to produce reactive oxygen species (ROS). The obtained ROS, in turn, promotes the oxidation of OPD to gain more DAP, causing the auto-inductive chromogenic reaction processes. This tandem chromogenic system is applied for visual colorimetric detection of TATP, allowing the selective and sensitive detection of TATP down to 42.8 μM. Moreover, analyses of TATP in real samples are performed, and the satisfactory recovery results are achieved. Furthermore, a field detection kit is also developed. Graphical abstract
研究领域:
分析化学
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爆炸物检测
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光化学
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比色传感器
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产品关联
DOI
PubMed
高影响因子
DRUG DELIVERY
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2022
·
IF 6.819
Dongliang Cheng,Zhiwei Wen,Hui Chen,Shiyuan Lin,Wei Zhang,Xin Tang,Wei Wu
To increase the antitumor drug concentration in the liver tumor site and improve the therapeutic effects, a functionalized liposome (PPP-LIP) with tumor targetability and enhanced internalization after matrix metalloproteinase-2 (MMP2)-triggered cell-penetrating peptide (TATp) exposure was modified with myrcludex B (a synthetic HBV preS-derived lipopeptide endowed with compelling liver tropism) for liver tumor-specific delivery. After intravenous administration, PPP-LIP was mediated by myrcludex B to reach the hepatocyte surface. The MMP2-overexpressing tumor microenvironment deprotected PEG, exposing it to TATp, facilitating tumor penetration and subsequent efficient destruction of tumor cells. In live imaging of small animals and cellular uptake, PPP-LIP was taken up much more than typical unmodified liposomes in the ICR mouse liver and liver tumor cells. Hydroxycamptothecin (HCPT)-loaded PPP-LIP showed a better antitumor effect than commercially available HCPT injections among MTT, three-dimensional (3 D) tumor ball, and tumor-bearing nude mouse experiments. Our findings indicated that PPP-LIP nanocarriers could be a promising tumor-targeted medication delivery strategy for treating liver cancers with elevated MMP2 expression.
研究领域:
药理学
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肿瘤学
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纳米技术
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药物递送系统
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产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）