Speed and precision: unveiling an ICP-MS method for ultra-trace 239Pu quantification in food
A rapid, accurate, and sensitive inductively coupled plasma mass spectrometry (ICP-MS) method has been developed and validated for the determination of ultra-trace levels of Plutonium-239 ( 239 Pu) in food. After ashing, samples were digested with lefort aqua regia and treated with FeCl 3 to mask phosphorus (P) interference, thereby preventing it from inhibiting the adsorption of Pu by the resin column. Subsequently, a two-stage TK200 resin column was employed for separation and purification, followed by ICP-MS analysis using kinetic energy discrimination (KED) mode. By combining a chromatographic column with ICP-MS, this method achieved an overall decontamination factor (DF) of 3.53×10 12 for uranium hydride ions ( 238 UH + ) and demonstrated excellent linearity within the given concentration range, with a correlation coefficient ( r ) exceeding 0.999. The limit of detection (LOD) was 3.6 fg/g (ash), with an average recovery of over 74% and a relative standard deviation below 6.6%. Furthermore, the proposed method's applicability was evaluated by quantifying 239 Pu in food. The results indicate that this method is rapid, accurate, and sensitive, making it ideal for 239 Pu detection.
危险品化学品经营许可证（带存储）