RSC Advances
·
2017
·Vol. 7
·期 74
·47091-47098
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IF 3.108
Yuling Liu,Longfei Lin,Jizheng Song,Ye Zhao,Zhimao Chao,Hui Li
Resveratrol (RES), a natural polyphenolic compound existing in plants, exhibits anticancer potential in inhibiting growth of various types of human cancers especially breast cancer. However, the poor aqueous solubility and low bioavailability limit its clinical application. Pluronic F127 (F127)-SS-Tocopherol (TOC) polymer is a redox-sensitive conjugate which has been synthesized by our previous study. Due to the amphiphilic properties of block copolymer F127-SS-TOC, RES was encapsulated by the F127-SS-TOC polymer and formed RES-loaded micelles (F127-SS-TOC/RES) in aqueous solution by self-assembly via a solvent evaporation method. The drug loading of F127-SS-TOC/RES micelles was 13.25 ± 2.29%, which remained stable for 7 days at 25 °C. The particle size and zeta potential of the above-mentioned micelles measured by dynamic light scattering (DLS) were 39.50 ± 1.39 nm and −4.55 ± 0.39 mV, respectively. Besides, F127-SS-TOC/RES micelles have significant cytotoxicity in human breast cancer cells MCF-7 and MDA-MB-231 compared to free RES and non-redox-sensitive F127-TOC/RES micelles. The results also showed that redox-sensitive F127-SS-TOC/RES micelles could induce apoptosis and elevate the intracellular reactive oxygen species (ROS) level against MDA-MB-231 cells. Hence, our results indicated that RES loaded F127-SS-TOC micelles hold potential in improving the treatment of breast cancer.
研究领域:
药剂学
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肿瘤学
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生物材料学
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DOI
高影响因子
JOURNAL OF HAZARDOUS MATERIALS
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2021
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IF 10.588
Ge Song,Xuedong Du,Yang Zheng,Pei Su,Yunping Tang,Minghua Zhou
To promote the reduction of Fe 3+ and improve the mineralization of organic pollutants , a novel electro-Fenton coupled with sulfite (Fe 3+ -EF/sulfite) process was constructed, which was superior to Fe 3+ -EF process in terms of carbamazepine (CBZ) degradation and mineralization with 5.99 times enhancement in degradation rate constant and 15.7 times enhancement on TOC removal. The complexation of Fe 3+ and sulfite prevented the precipitation of Fe 3+ , reduced Fe 3+ to Fe 2+ , and accelerated the iron cycle, so that H 2 O 2 utilization efficiency (0.051 mg TOC mg H2O2 −1 ) was greatly improved and electric energy consumption was greatly reduced (0.081 kWh g −1 TOC). The quenching experiments and EPR test confirmed that the reactive species, such as SO 3 •- , SO 4 •- , • OH, O 2 •- and 1 O 2 were responsible for the degradation of CBZ. This process also expanded the pH application range from 3 to 9 with satisfactory CBZ removal efficiency. This work verified the suitability of the Fe 3+ -EF/sulfite process for different sulfites (sulfite and bisulfite), typical pollutants (atrazine, sulfamethazine, rhodamine B) and real wastewater with 2.1–18.7 folds enhancement in degradation rate. The Fe 3+ -EF/sulfite process can achieve deep mineralization with low cost and simple operation, which has a broad and cost-effective application prospect in removal of refractory organic pollutants.
研究领域:
环境科学
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水处理技术
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产品关联
DOI
PubMed
高影响因子
SEPARATION AND PURIFICATION TECHNOLOGY
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2023
·
IF 8.6
Yusi Tian,Xuyang Zhang,Minghua Zhou,Ying Zhang
A bifunctional cathode with MoS 2 powder and carbon black deposited on carbon felt (MCB@CF) was prepared and first applied as bifunctional cathode to heterogeneous electro-Fenton (EF). This cathode presented higher H 2 O 2 production compared with other cathodes. Fe 0 modified by sulfidation coupled with pre-magnetization (pre-S/Fe 0 ) was used as a catalyst in the EF process. Compared to the conventional EF process, the established pre-S/Fe 0 -EF-MCB@CF process showed higher sulfamethazine (SMT) removal (removal rate constant improved by 3.01 times) and TOC removal (40% in 1 h) within wide pH range (pH 4–10). According to the radical quenching experiment, •OH was proved to be the main oxidation species for SMT degradation and O 2 •- played a marginal role. MoS 2 surface presented Mo 4+ active sites that could promote the conversion of Fe 3+ to Fe 2+ , during which Mo 4+ was oxidized to Mo 6+ . The promoted reduction of Fe 3+ to Fe 2+ enhanced the utilization of H 2 O 2 and thus the generation of ∙OH. The six consecutive runs of pre-S/Fe 0 -EF-MCB@CF process proved the excellent stability and reusability of prepared MCB@CF cathode. Compared with that by Fe 0 -EF-CB@CF process, the removal rates of pesticides, phenols, dyes and drugs by pre-S/Fe 0 -EF-MCB@CF process was enhanced more than two times, demonstrating the potential of this process for wide application. This study provides a green and sustainable approach for the treatment of refractory pollutants by heterogeneous EF process in a wide pH range.
研究领域:
环境科学
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水处理技术
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产品关联
DOI
高影响因子
JOURNAL OF HAZARDOUS MATERIALS
·
2023
·
IF 13.6
Xukai Li,Weirui Chen,Dongpo Liu,Gaozu Liao,Jing Wang,Yiming Tang,Laisheng Li
Due to its low interfacial electron migration ability and highly hydrophilic, Fe-MCM-41 (FeM) had poor activity and stability during catalytic ozonation . To this end, the secondary metal Zn and Si-F group were introduced into the framework of FeM to create surface potential difference and hydrophobic sites. Comparative characterizations showed that there existed rich acid sites with great potential difference on F-Fe-Zn-MCM-41 (FFeZnM). Additionally, because of the existence of hydrophobic and electron-withdrawing Si-F unit, the electron migration ability, hydrophobicity and acidity of FFeZnM were enhanced. The greater O 3 mass transfer was induced by Si-F group and O 3 was directly activated at Fe and Zn Lewis acid sites into •OH, •O 2 - and 1 O 2 . With •OH acting as main species, FFeZnM/O 3 achieved the superior IBP removal (93.4%, 30 min) and TOC removal (46.6%, 120 min) over those of sole O 3 and F-FeM/O 3 processes, respectively. HCO 3 - , Cl - , NO 3 - and SO 4 2- hindered IBP degradation by FFeZnM/O 3 , but high concentration humic acid (HA) exhibited promotion by forming HA-IBP complex. IBP degradation by FFeZnM/O 3 was enhanced with tap water , river water, and effluent from the secondary sedimentation tank of the sewage plant acting as medium. This study proposed an innovative approach to catalyst design for catalytic ozonation.
研究领域:
环境科学
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材料科学
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产品关联
DOI
PubMed
高影响因子
SCIENCE OF THE TOTAL ENVIRONMENT
·
2018
·
IF 4.61
Yang Yu,Fei Huang,Yide He,Xiyang Liu,Chenjing Song,Yanhua Xu,Yongjun Zhang
In this study, heterogeneous Fenton-like degradation of ofloxacin (OFX) was investigated by sludge derived carbon (SC). The effects of SC catalyst, temperature and pH on the efficiency of ofloxacin degradation were investigated. SC treated with sulfuric acid (SC-H 2 SO 4 ) performed high catalytic activity , indicating that sulfate group produced low pH of the surface and was beneficial for heterogeneous Fenton-like degradation. The removal of ofloxacin and TOC was 91.5% and 62.3%, respectively, after 180 min adsorption and 540 min oxidation, at pH 6 and a dosage of 138 mg L −1 H 2 O 2 . It was found that OFX conversion increased with the decrease of pH and OFX was degraded under the wide range of pH (3–6) by SC-H 2 SO 4 . These promising results clearly demonstrate the potential of the heterogeneous Fenton-like process for the effective degradation of ofloxacin by SC-H 2 SO 4 . Based on intermediated products identified by gas chromatography–mass spectrometry, a possible OFX oxidation pathway in Fenton-like reaction was proposed.
研究领域:
环境科学
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化学工程
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产品关联
DOI
PubMed
高影响因子
CHEMOSPHERE
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2022
·
IF 8.943
Zekun Dong,Yan Zhang,Jie Yao
Electro-peroxone (EP) is an emerging advanced oxidation process which combines electro-generation H 2 O 2 and ozone for removing organic contaminants . In this paper, a platinum plate as anode, a method of electrochemical oxidation is adopted to modify graphite felt (GF) cathode to promote H 2 O 2 yield and TOC removal from oxalic acid solution in EP process, its performance, mechanism and stability were discussed. Compared with original GF cathode, 2.6 times H 2 O 2 yield can be achieved by the 5 min electrochemically modified GF (GF-5). The high electrochemical activity of the modified GF can be ascribed to introducing numerous surface oxygen-containing functional groups (OGs), which not only decreased the impedance, but also increased the amount of active site of O 2 reduction. The production of H 2 O 2 with GF-5 cathode improved with the increased initial pH, cathodic potential and O 2 flow rate, while this promoting effect was not observed in GF cathode. Compared with GF cathode, TOC removal rate was improved by 21.5% with GF-5 cathode due to higher H 2 O 2 yield in EP process. The primary pathway of TOC removal is electrochemically-driven peroxone process, and hydroxyl radical (·OH) is the dominant reactive species. Furthermore, GF-5 cathode had a good stability due to the protection of H 2 O 2 and free electrons injected. The results indicate that the electrochemically modified GF severed as the cathode of EP processes has significant efficiency and stability in the removal of ozone-refractory organic contaminants .
研究领域:
环境科学
·
电化学工程
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DOI
PubMed
高影响因子
CHEMOSPHERE
·
2024
·
IF 8.1
Xu Yin,Jie Zhang,Siru Chen,Wei Li,Hongwei Zhu,Kajia Wei,Yonghao Zhang,Haoming Chen,Weiqing Han
In this work, an electric field-enhanced heterogeneous catalytic ozonation (EHCO) was systematically investigated using a prepared FeOx/PAC catalyst. The EHCO process exhibited high sulfadiazine (SDZ) and TOC removal efficiency compared with electrocatalysis (EC) and heterogeneous catalytic ozonation (HCO) process. Almost 100% of SDZ was removed within 2 min, and the TOC removal reached approximately 85% within 60 min. Quenching experiments and EPR analysis suggested that the prominent SDZ and TOC removal performance is supported by the enhanced ·OH generation ability. Further study proved that H 2 O 2 formed by O 2 electrochemical reduction, peroxone reaction and electrochemical reduction of ozone contributed to improving ·OH generation. Furthermore, the EHCO system showed satisfactory stability and recyclability compared to conventional HCO systems, and the SDZ and TOC removal rates were maintained at ≥95% and ≥70% in 16 consecutive recycles, respectively. Meanwhile, XPS analysis and Boehm's titration for the FeOx/PAC catalyst used in HCO and EHCO process confirmed that the external electron supply could restrain the oxidation of surface functional groups of PAC and maintain a balance of the Fe(II)/Fe(III) ratio, which proved the critical role of cathode reduction in catalyst in situ regeneration during long consecutive recycles. In addition, the EHCO system could achieve more than 80% SDZ removal within 2 min in different water matrices. These results confirmed that the EHCO process has a wide application perspective for refractory organics removal in actual wastewater.
研究领域:
环境科学
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催化化学
·
水处理工程
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产品关联
DOI
PubMed
高影响因子
JOURNAL OF MEMBRANE SCIENCE
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2020
·
IF 7.183
Songxue Wang,Jiayu Tian,Linran Jia,Jialin Jia,Sujie Shan,Qiao Wang,Fuyi Cui
CuO catalyst dispersed in the feed water (CDF) and CuO catalyst immobilized on the ceramic hollow fiber membrane (CIM) for peroxymonosulfate (PMS) activation were developed and employed in the submerged membrane filtration systems for drinking water treatment , respectively. The performance of the CDF and CIM systems was systematically investigated and compared. The result indicated that BPA concentration, PMS dosage and CuO content exerted much less influence on BPA degradation in the CIM system as compared with that in the CDF system. The CIM system exhibited a greater advantage in the performance of BPA degradation and TOC removal when treating a large volume of feed (>300 mL). In addition, the effect of actual water matrix on the two systems was evaluated. The CIM system showed higher resistance to the adverse influence and better anti-fouling performance than the CDF system. The comparative study on the performance of CDF and CIM systems provides meaningful information for developing the process of membrane filtration coupled with PMS oxidation .
研究领域:
环境科学
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水处理工程
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产品关联
DOI
高影响因子
Journal of Water Process Engineering
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2019
·
IF 3.173
Senlin Ma,Xingtao Zuo,Juan Xiong,Cong Ma,Zhongbing Chen
An ozonation process combined with hydrophobic adsorbent high silica ZSM-5 (HSZSM-5) was designed to enhance sulfamethoxazole (SMX) removal and reduce the ozone consumption. The promoted effect of HSZSM-5 on SMX removal was investigated in terms of SMX removal and TOC removal efficiency as well as the ozone consumption. The impacts of pH and CO 3 2− /HCO 3 - were also analyzed. The presence of HSZSM-5 helped to increase the SMX degradation and TOC removal efficiency and their kinetics rate constants. HSZSM-5 adsorption behaviors for SMX and its degradation intermediates were responsible for the findings. Direct ozone oxidation was the main mechanism of SMX removal as HZSM-5 could not contribute to producing H 2 O 2 and •OH. Much higher CO 3 2− /HCO 3 - concentration (≥10 mM) and pH value (>7) were in favor of SMX degradation. HSZSM-5 had a positive contribution to SMX removal. The mass ratio of ozone consumption to the removed SMX reduced to 0.63 g O 3 /g SMX. This system of introducing high silica zeolite in the ozonation/adsorption process is an environmentally and economically sound technology to removal micropollutants.
研究领域:
环境科学
·
水处理技术
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DOI
高影响因子
CHEMOSPHERE
·
2019
·
IF 5.108
Chengzhi Zhou,Yanping Wang,Jie Chen,Lei Xu,Haiming Huang,Junfeng Niu
Electrochemical degradation of antiviral drug abacavir was investigated by using a penetration flux porous Ti/SnO 2 –Sb anode prepared by sol-gel method. The effects of applied current density, initial pH, and inorganic anions on the degradation kinetics were systematically studied. Degradation efficiency more than 97% was performed in only 10 min at a current density of 0.2 mA cm −2 . The corresponding degradation rate constant and the lowest electrical energy per order were calculated to be 0.36 min −1 and 6.5 mWh L −1 , respectively. Extending the reaction duration to 5 h, 53.3% of TOC removal was observed. The results indicated that effective degradation of abacavir appeared in the penetration flux porous Ti/SnO 2 –Sb anode with a very low energy consumption. Furthermore, the electrochemical intermediate products and the reaction site during abacavir degradation were detected and recognized. The quantitative structure-activity relationship model revealed that the potential risks of abacavir to the aquatic organism, such as fish, greatly decreased after flowing through the penetration flux porous Ti/SnO 2 –Sb anode.
研究领域:
环境科学
·
药学
✓ 已验证
DOI
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2018
·
IF 6.735
Jiang Lu,Jingxiang Sun,Xixi Chen,Shuanghong Tian,Dingsheng Chen,Chun He,Ya Xiong
Herein a novel coupling process of simultaneous catalytic ozonation and photocatalysis (SCOP) using a bifunctional catalyst for the antibiotics wastewater treatment was developed. MgMnO 3 , as the first example of bifunctional catalyst, was successfully prepared by a simple sol-gel method. In the MgMnO 3 -mediated SCOP process, the TOC removal of sulfamethoxazole, tetracycline, ciprofloxacin, and trimethoprim within 80 min reached 94.7 ± 0.9%, 88.4 ± 0.9%, 97.8 ± 1.0%, and 76.3 ± 0.9%, respectively, much higher than that in ozonation or photocatalysis (less than 20%). The first order kinetics reaction constant of TOC removal in the case of tetracycline degradation by SCOP is 2.58 × 10 −2 min −1 , which is 2.7, 23.0, and 6.2 times that by catalytic ozonation, photocatalysis, and photo ozonation, respectively. ESR spectra show that much more ·OH radicals are generated in SCOP than the sum in photocatalysis and catalytic ozonation processes, indicating the synergism between two processes and explaining the high mineralization efficiency in SCOP. Finally, eight intermediates were identified by LC-MS analysis and the initial degradation pathway of tetracycline in SCOP was proposed. Excellent treatment efficiency, high ozonation utilization (>93%) and low energy consumption (14.9 KJ/mg TOC) suggest that SCOP is a promising choice for antibiotics-containing wastewater treatment.
研究领域:
环境科学
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化学工程
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产品关联
DOI
高影响因子
APPLIED CATALYSIS B-ENVIRONMENTAL
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2013
·
IF 5.825
Qizhou Dai,Jiayu Wang,Jie Yu,Jun Chen,Jianmeng Chen
A magnetic core/shell CeO 2 nanometer catalyst particle of Fe 3 O 4 @SiO 2 @CeO 2 for ozonation was prepared and the catalytic activity was evaluated by the degradation of acetylsalicylic acid (ASA). The characterizations of the magnetic nanoparticles, such as TEM, XRD and EDX, showed that Fe 3 O 4 @SiO 2 @CeO 2 had a ternary structure with a Fe 3 O 4 magnetic core, a silica membrane mid-layer and CeO 2 outer layer. The catalysts of Fe 3 O 4 @SiO 2 @CeO 2 showed an obviously high efficiency in catalytic ozonation on the degradation of ASA, and thus could also enhance the TOC removal. The ASA removal with Fe 3 O 4 @SiO 2 @CeO 2 catalyst at 60 min could reach 81.0%, while 67.3% with Fe 3 O 4 @SiO 2 , 66.1% with Fe 3 O 4 and only 64.1% with ozonation alone. Fe 3 O 4 @SiO 2 @CeO 2 catalysts could also enhance the ozone utilization during the reaction. The effect of radical scavengers showed that the high removal efficiency of catalytic ozonation over Fe 3 O 4 @SiO 2 @CeO 2 may be mainly attributed to surface reactions. According to stability and recyclability test of the Fe 3 O 4 @SiO 2 @CeO 2 catalysts, the results showed that the catalysts would be helpful in the separation and magnetic recyclability. In addition, based on the intermediates detected by GC/MS, a possible degradation pathway of ASA was proposed.
研究领域:
环境科学
·
催化材料
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产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）