SEPARATION AND PURIFICATION TECHNOLOGY
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2024
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IF 8.1
Jianhua Zu,Jingjie Diao,Gang Han,Wenjuan Xue,Xiaohan Pan,Mingjie Jin,Qing Tang
In this study, a carboxyl-functionalized covalent organic framework (COF) rich in nitrogen (N) and oxygen (O) functional groups was prepared and characterized, which provided a new opportunity for the efficient and rapid treatment of radioactive contamination in nuclear wastewater. The synthesis of the COF (Tp-DTA) was constructed using 1,3,5-triformylphloroglucinol (TFP) and 2,5-diaminoterephthalic acid (DTA), providing a large specific surface area, mesoporous pore, and abundant coordination sites with high adsorption capacity and exceptional affinity for Sr 2+ . Batch adsorption experiments exhibited that Tp-DTA achieved a maximum adsorption capacity of 145.4 mg/g for Sr 2+ in alkaline solutions, reaching adsorption equilibrium within 60 min. Tp-DTA exhibited rapid kinetics for 90 Sr, with the amounts of 90 Sr removed more than 95% within 3 min. In the presence of coexisting ions (Na + , K + , Cs + , Mg 2+ , and Ca 2+ ), Tp-DTA displayed excellent preferential selectivity for Sr 2+ and high removal efficiency. Even in simulated groundwater containing multiple complex ions, Tp-DTA demonstrated a strong affinity for Sr 2+ and showed practical applicability with a nearly 100% removal efficiency for 90 Sr. XPS and FTIR characterizations confirmed that the adsorption mechanism of Sr 2+ involved chelation exchange between the carboxyl groups of Tp-DTA and Sr 2+ in the solution. Furthermore, the desorption efficiency of HCl (>0.01 mol/L) can reach 95% and five cyclic desorption-adsorption experiments demonstrated the reusability of Tp-DTA, endowing the carboxyl-functional COF with great potential in the treatment of 90 Sr-contaminated radioactive wastewater and environmental remediation.
研究领域:
环境科学
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材料科学
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放射化学
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高影响因子
JOURNAL OF FOOD COMPOSITION AND ANALYSIS
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2025
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IF 4.6
Xingyan Liu,Jinfeng Zhao,Jie Hao,Ying Zhang,Weiyi Cui,Dawei Lou,Xiyue Wang
The solvothermal approach was used to create a three-dimensional covalent organic framework (TP-PA) using p-phenylenediamine (PA), 1,3,5-triformyl phoroglucinol (TP), and anhydrous ethanol as the solvent. It was utilized as a coating material for needle trap devices (NTD) to determine five polychlorinated biphenyls (PCBs) from milk coupled with gas chromatography (GC). The results displayed that TP-PA presented excellent extraction performance to PCBs owing to its abundant micro/mesopores structure, high specific surface area and good chemical and thermal stability. The proposed needle-type micro-extraction (NTME)-GC method had wide linearity (0.025–200 μg L −1 ) with R 2 ≥ 0.9928, low limits of detection (0.0072–0.0146 μg L −1 ), and good single device repeatability and device-to-device reproducibility with the relative standard deviations (RSDs) below 7.07 %. It was applied to detect five trace PCBs in milk, and satisfactory spiked recoveries were obtained (79.7 %∼96.4 %) with relative standard deviations less than 11.9 %. The above results indicated that the method has excellent application potential for detecting PCBs in food.
研究领域:
分析化学
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环境科学
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食品安全
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材料科学
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高影响因子
MOLECULES
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2022
·Vol. 27
·期 12
·3686
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IF 4.927
Xinlong Wang,Huahui Zeng,Xin Zhu,Duanjie Xu,Qikang Tian,Can Wang,Lingzhou Zhao,Junwei Zhao,Mingsan Miao,Xiangxiang Wu
Triptolide (TP) is a potential drug candidate for the treatment of cancer, but its use was hampered by its systemic toxicity and poor water solubility. Hence, a TP-CSO prodrug was synthesized by conjugating TP to chitosan oligosaccharide (CSO), and characterized by1H NMR, FTIR, DSC and XRD analyses. The TP-CSO containing about 4 wt% of TP exhibited excellent water solubility (15 mg/mL) compared to TP (0.017 mg/mL). Compared with TP, the pharmacokinetics of the conjugate after oral administration showed a three-fold increase in the half-life in the blood circulation and a 3.2-fold increase in AUC(0–∞). The orally administered TP-CSO could more effectively inhibit tumor progression but with much lower systemic toxicity compared with TP, indicating significant potential for further clinical trials. In conclusion, CSO-based conjugate systems may be useful as a platform for the oral delivery of other sparingly soluble drugs.Keywords:triptolide;toxicity;water solubility;pharmacokinetics;pancreatic cancer
研究领域:
药学
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癌症研究
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药物递送系统
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PubMed
高影响因子
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
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2025
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IF 4.6
Shan Sun,Dan Yang,Zheng Li,Wei Cheng,Yanli Yang,Ling Li,Xiangjie Luo,Yong Qian
Biogenic amines (BAs) are a class of nitrogen-containing natural organic compounds. Elevated levels of BAs are a reliable indicator of food spoilage and pose a significant risk to human health. Thus, the development of real-time sensors for BAs monitoring is crucial. In this study, we present a novel fluorescence probe, TP-A , based on ylidenemalononitrile enamine, which can detect various BAs including putrescine, cadaverine, and spermine. TP-A exhibits a significant fluorescence intensity increase at 600 nm in the presence of these BAs in an aqueous system, which can effectively monitor BAs in representative vegetable onion tissues. Notably, TP-A -loaded filter paper has been developed into test strips for real-time monitoring of BAs released from shrimp under different temperatures. This work offers a precise method for probing the release of BAs in real food samples, which is promising for application in food quality control.
研究领域:
食品科学
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分析化学
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生物化学
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DOI
PubMed
高影响因子
TRANSPLANTATION
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2024
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IF 5.3
Jia Degong,Wu Kun,Luo Jiefu,Xu Xuesong,Pan Wei,Zhao Minjie,Li Shengwei,Gong Jianping,Gong Junhua
Background. Donation after circulatory death livers are more susceptible to ischemia/reperfusion injury (IRI) because of a longer period of warm ischemia. Growing evidence now suggests that ferroptosis plays a key regulatory role in the development of IRI, so targeting ferroptosis may be an effective strategy to alleviate IRI in liver transplantation (LT). Methods. Using donation after circulatory death LT models in rats and oxygen-glucose deprivation/reoxygenation (OGD/R) models in BRL-3A cells, we tested the effect of the Chinese medicine monomer wogonin on liver IRI and explored the specific mechanism. Results. Wogonin attenuated liver IRI and increased the survival rate of rats by inhibiting lipid peroxidation and ferroptosis. Mechanistically, arachidonic acid 15-lipoxygenase-1 (ALOX15) and inducible nitric oxide synthase (iNOS) were identified as potential targets of baicalein through bioinformatics analysis combined with in vivo and in vitro experiments. This result was further confirmed by molecular docking and cellular thermal shift assays. Finally, we silenced ALOX15 and iNOS in the OGD/R cell model and found that silencing ALOX15 and iNOS could reproduce the regulatory effect of wogonin and abrogate the regulatory effect of wogonin. Conclusions. In brief, this study emphasizes that wogonin exerts a protective effect in liver IRI through the regulation of ALOX15- and iNOS-mediated ferroptosis. ALOX15 and iNOS are potential targets for intervention in IRI induced by LT, and wogonin is a drug candidate for LT patients. Export
研究领域:
移植医学
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药理学
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分子生物学
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PubMed
高影响因子
JOURNAL OF APPLIED POLYMER SCIENCE
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2026
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IF 2.8
Hong Ji,Kexin Hao,Song Zheng,Ke Yang,Zhixiang Xing
With the intensification of industrial activities, oil pollution in water bodies has become increasingly severe, necessitating the development of highly efficient and environmentally friendly oil–water separation technologies. This study employed a combined impregnation and vacuum filtration method to modify mixed cellulose ester (MCE) membranes with tea polyphenols (TP) and hydrophilic silica (SiO 2 ) nanoparticles, creating SiO 2 /TP-MCE composite membranes exhibiting high hydrophilicity and submerged oleophobicity. Results indicate that TP modification significantly enhances membrane surface hydrophilicity, reducing the water contact angle to 62° after 24 h immersion and achieving a water flux of 31,217.1 L·m −2 ·h −1 , representing a 2.85-fold increase over the original membrane. The incorporation of SiO 2 further endows the membrane surface with high hydrophilicity and underwater superhydrophobicity. The optimal composite membrane (M5) achieved a separation efficiency of 99.6% for diesel emulsion, demonstrating excellent anti-fouling properties and cycling stability. Based on green and sustainable materials and processes, this composite membrane holds broad application prospects in industrial oily wastewater treatment and marine oil spill emergency response.
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Solar RRL
·
2022
·Vol. 6
·期 6
·2200101
·
IF 9.173
Han Li,Hongkang Gong,Mengjie Sun,Huimin Zhang,Chao Ji,Chunjun Liang,Fangtian You,Xiping Jing,Xiangfei Kong,Zhiqun He
A donor–acceptor (D–A)-type discotic organic material (TP-2-PIE), having a self-organization ability, is selected to be the third component blending with poly[4,8-bis(5-(2-ethylhexyl)thiophen-2-yl)benzo[1,2-b:4,5-b’]dithiophene - co-3-fluorothieno [3,4-b]-thiophene-2-carboxylate] (PTB7-Th): [6,6]-phenyl-C 71 -butyric acid methyl ester (PC 71 BM) in ternary bulk-heterojunction polymer solar cells. The complementary absorption and energy transfer between TP-2-PIE and PTB7-Th contributes to the enhancement in photocurrent generation, improving the short-circuit current. In addition, TP-2-PIE alters the molecular interaction leading to an enhanced phase separation, which promotes carrier transport with a good balance and minimizes the density of trap states simultaneously. In this way, the overall photovoltaic performances are markedly enhanced at an optimal condition of 10 wt% TP-2-PIE in donors with a 12.6% efficiency increase. Current understanding on the functionality of this third component in ternary solar cells may be able to guide future device development.
研究领域:
材料科学
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光伏技术
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高影响因子
INTERNATIONAL JOURNAL OF HYDROGEN ENERGY
·
2026
·
IF 9.2
Yu Han,Liting Lai,Weiye Zhang,Rui Li,Wenbei Jia,Ruixuan Chu,Shipeng Wan,Xuan Liu,Qin Zhong,Zhaoxiang Zhong
This photocatalyst was prepared using an ultrasonic-assisted hydrothermal method regulated by iodide ions. • The resultant Zn 0.2 Cd 0.8 S/TP-PCN exhibits a flake-like structure enveloping the nanospheres. • The Zn 0.2 Cd 0.8 S/TP-PCN exhibited an excellent H 2 evolution rate of 2.83 mmol g −1 h −1 in alkaline PET solution. • Photoreduction mechanism of Zn 0.2 Cd 0.8 S/TP-PCN is proposed and analyzed. Zn 0.2 Cd 0.8 S/TP-PCN nanocomposite photocatalysts were prepared via an ultrasound-assisted hydrothermal method regulated by iodide ions. The resulting composite features intimate interfacial contact and strong electronic coupling, generating a built-in electric field that promotes efficient charge separation and directional transfer while suppressing the photocorrosion of Zn 0.2 Cd 0.8 S. As a result, this composite exhibits an excellent hydrogen evolution rate of 2.83 mmol g −1 h −1 in an alkaline PET solution, which is approximately 4.7 times that of pure TP-PCN. Liquid-state NMR analysis confirms that PET is effectively degraded into small organic molecules such as methanol and formate, demonstrating efficient PET upcycling coupled with hydrogen production. Mechanistic investigations demonstrate that the reaction proceeds via a direct hole-driven oxidation pathway coupled with electron-mediated hydrogen evolution, consistent with a Z-scheme charge transfer mechanism. This work provides a promising strategy for coupling plastic waste upcycling with sustainable hydrogen production, offering new insights into addressing both environmental and energy challenges. Download: Download high-res image (345KB) Download: Download full-size image
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JOURNAL OF THE TEXTILE INSTITUTE
·
2023
·
IF 1.7
Jie Wu,Shuqiang Liu,Gaihong Wu,Man Zhang,Yifan Jing,Jingjing Li,Md Moinul Hossain Patowary,Romen Chakma,Cailiu Wang,Fu Li,Lu Jia,Yujing Zhang,Dongdong Lu
This paper presented the composite antibacterial agent of nano-silver (Ag) and tea polyphenol (TP) by bioreduction method. Then polylactic acid (PLA) nanofiber membranes with different antibacterial content were prepared by electrostatic spinning method. The morphologies, structural characteristics and properties of electrostatic spun fiber membranes were investigated by scanning electron microscope (SEM), infrared spectroscopy (FTIR), electronic single fiber strength machine and flat colony counting method. The results showed that Ag@TP was loaded with silver nanoparticles with uniform particle size distribution. When the content of Ag@TP of electrospun fiber was less than 2.0%, the diameter of electrostatic spinning fiber was uniformly distributed and had smooth surface. It could be seen from the FTIR spectrum that Ag@TP and PLA were well compounded through valence bonds. As the content of antibacterial agent increased, the elongation at break of the fiber membrane first decreased and then increased. While the breaking strength was found to first decrease, then increase and decrease again. The water contact angle of the fiber membrane was gradually decreased with the increase of the antibacterial agent content. When the amount of Ag@TP was added 2.0%, the relative antibacterial rate of the electrospun fiber membrane to E.coli and S.aureus was as high as 95%, indicating an excellent antibacterial effect.
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高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2026
·
IF 12.5
Xueying Shan,Qixin Huang,Jiao Gao,Hanchao Liu,Jingru Wang,Jinchun Li
The design of low-smoke and low-toxicity epoxy resin (EP) composite materials remained a significant challenge. In this study, a multifunctional MOF-based flame retardant (TP-P-Co-MOF) was synthesized using ZIF-67 as the framework via a three-step modification process. TP-P-Co-MOF incorporated Schiff base-conjugated structures, Co P synergistic flame-retardant sites, and a porous architecture, while exhibiting excellent compatibility with EP. At a 4 wt% loading, the EP/TP-P-Co-MOF composite attained a UL-94 V-0 classification and an LOI of 31.3%. Additionally, in comparison with EP, the EP/TP-P-Co-MOF composite exhibited marked reductions in the peak heat release rate (PHRR), total heat release (THR), peak smoke production rate (PSPR), and total smoke production (TSP), which decreased by 43.1%, 14.9%, 64.0%, and 52.6%, respectively, thereby demonstrating outstanding flame-retardant efficiency and toxic-smoke suppression performance. Investigation of the flame-retardant mechanism indicated that TP-P-Co-MOF not only significantly improved the quality of the graphitized carbon layer in EP, but also reduces the concentration of combustible gases, thereby exerting synergistic flame-retardant effects in both the condensed and gas phases. With respect to mechanical properties, the incorporation of TP-P-Co-MOF improved both the toughness and strength of the EP. The tensile strength and impact strength increased by 11.1% and 24.7%, respectively, in comparison with neat EP. This study provided a promising strategy for developing highly efficient MOF flame retardants while offering a novel approach to designing low-smoke, low-toxicity flame-retardant EP.
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CHEMICAL ENGINEERING JOURNAL
·
2025
·
IF 13.2
Bingfan Li,Xiaowen Qian,Wenbo Wu,Shiyuan Liu,Shijun Wu,Jiang Han,Yong Han,Chao Yang,Tifeng Jiao
Plastic pollution and the treatment of oily wastewater have become significant challenges in the field of environmental protection. This study presents a method for fabricating electrospun membranes from waste polyethylene terephthalate (PET) beverage bottles, which are surface-modified by co -depositing tea polyphenols (TP), 3-aminopropyltriethoxysilane (APTES), and tetraethoxysilane (TEOS). The resulting superhydrophilic membrane, denoted as PET-T-100, exhibits excellent mechanical properties and structural stability due to the optimization of precursor solution composition and electrospinning parameters. The modified membrane shows a water contact angle of 0° in air and an underwater oil contact angle of 161°, demonstrating outstanding wettability. In oil-water separation experiments, PET-T-100 achieves a separation efficiency of over 99.5 % for various oil-water mixtures, and over 98 % for emulsions, maintaining stable wettability and separation performance even in harsh acidic, alkaline, and saline environments. This study provides an efficient and environmentally friendly approach for the high-value utilization of waste PET and offers a novel strategy for the development of high-performance oil-water separation membranes and environmental remediation technologies.
研究领域:
环境科学
·
材料科学
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化学工程
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废水处理
·
聚合物回收
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高影响因子
ENVIRONMENTAL SCIENCE & TECHNOLOGY
·
2025
·
IF 11.3
Zhenhua Dai,Jihong Xu,Jian Guan,Mingyang Feng,Yang Liu,Cuili Xing,Xuanying Cai,Shuchen Wang,Lushi Lian,Hongyu Dong,Zhiyong Jason Ren,Wei Shi,Alicia Kyoungjin An,Shifa Zhong,Xiaohong Guan
Chemical oxidation is pivotal in remediating organic pollutants in aquatic systems; however, it frequently yields transformation products (TPs) with potential toxicological profiles surpassing those of the parent pollutants. Comprehensive identification of these TPs is imperative for environmental risk assessment and optimization of oxidation methodologies. Traditional experimental approaches for TP elucidation are often hindered by substantial financial and technical constraints, limiting their applicability in high-throughput scenarios. Here, we introduce TP-Transformer, an advanced deep learning framework designed to predict both the structures of TPs and their corresponding formation pathways. Trained on Chem_Oxi_2K, a meticulously curated data set comprising 2780 pollutant degradation reactions, TP-Transformer achieved a notable accuracy of 86.28% in TP prediction. The model adeptly reconstructs complete degradation pathways, addressing the intricate challenge of pathway elucidation. Attention analyses indicate that the TP-Transformer discerns reactive moieties within substrates and correlates them with specific reaction conditions, emulating expert-level chemical reasoning. Experimental validations corroborate the model’s robustness, with accurate TP predictions ranging from 80.20 to 92.86% for five pollutants absent from the training data set. These findings underscore TP-Transformer’s potential to transform environmental chemistry by offering a scalable, precise, and efficient alternative to traditional experimental methodologies, thereby enhancing water treatment strategies and safeguarding ecological and human health.
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高影响因子
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