MICROCHEMICAL JOURNAL
·
2021
·
IF 4.821
Miaomiao Li,Xiuying Peng,Yujie Han,Lifang Fan,Zhiguang Liu,Yujing Guo
MXenes are attractive for various biosensors owning to their tunable versatile properties. Herein, Ti 3 C 2 nanosheets (Ti 3 C 2 NSs) were found to possess intrinsic peroxidase-like activity, and which could be enhanced by single-stranded DNA (ssDNA) adsorbed on the nanosheets. Hence, a simple label-free sensing strategy was developed for colorimetric detection of biomolecules, based on Ti 3 C 2 NSs as a peroxidase mimic enzyme and ssDNA aptamer as an enzymatic activity enhancement factor along with a recognition substance for the target. In the presence of target biomolecules, the aptamers were desorbed from Ti 3 C 2 NSs due to the specific binding of targets to aptamers, thus bringing about the decrease of catalytic activity. Thrombin (TB) as the model was determined by this constructed biosensor with a linear range of 1.0 × 10 −11 to 1.0 × 10 −8 M, and evaluated subsequently in the real blood samples with satisfactory results. This work highlights Ti 3 C 2 MXenes as a nanomaterial mimic enzyme (called nanozyme) for monitoring biomolecules by target-specific recognition strategy.
研究领域:
生物传感
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材料科学
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医学检测
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DOI
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2023
·
IF 15.1
Hao Ai,Siyu Jian,Yuan Yao,Kaifeng Du
Designing and tuning macropores into aligned structure is of considerable importance in promoting mass transfer, improving chromatographic performance and enhancing column efficiency. Herein, we have synthesized an innovative aligned porous Chitosan/Ti 3 C 2 MXenes monolith via a facile, versatile and reproducible unidirectional “freeze-casting” method. Typically, the accumulation of Ti 3 C 2 MXenes directs the formation of aligned structure during the unidirectional freezing process and thus aligned macropores are formed by a subsequent freeze-drying process. By various physical characterization, the distribution of aligned macropores, micropores and specific surface area are determined to be 21 μm, 2.53 nm and 103.09 m 2 ·g −1 , respectively. In addition, monolith bed permeability is calculated to be 1.94 × 10 -12 m 2 , approximately 10 times than conventional monolith. Batch adsorptive experiments confirm that adsorptive capacities to bovine serum albumin and bovine hemoglobin are remarkably elevated on account of the high affinity of proteins onto those imbedding Ti 3 C 2 MXenes. Meanwhile, continuous mass transfer equation describes the aligned macropores facilitate the film mass transfer factor ([ k L a ] f ) in a separation process thus driving the global mass transfer factor ([ k L a ] g ). It is expected that the aligned porous Chitosan/Ti 3 C 2 MXenes monolith promises great potential for a continuous separation of proteins when a wholesale production is required.
研究领域:
生物材料
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分离科学
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生物化学
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产品关联
DOI
高影响因子
ANALYST
·
2021
·Vol. 146
·期 8
·2664-2669
·
IF 4.616
Liling Lu,Xiao Han,Jingwen Lin,Yingxin Zhang,Minghao Qiu,Ying Chen,Meijin Li,Dianping Tang
Herein a rapid and sensitive fluorometric bioanalysis platform for mercury(II) (Hg2+) detection was innovatively developed using ultrathin two-dimensional MXenes (Ti3C2) as fluorescence quencher and Hg2+-induced exonuclease III (Exo III)-assisted target recycling strategy for efficient signal amplification. Initially, fluorophore-labeled single-stranded DNA (FAM-labeled probe) can be easily adsorbed onto the surface of ultrathin Ti3C2 nanosheets by hydrogen bonding and metal chelating interaction, and the fluorescence signal emitted by the FAM-labeled probe is quenched strongly owing to the fluorescence resonance energy transfer between the FAM and ultrathin Ti3C2 nanosheets. Upon sensing the target Hg2+, the protruding DNA fragment at the 3′ end of hairpin will hybridize with primer (hairpin-Hg2+-primer), and then further digested by Exo III to produce a probe (nicker). The released target Hg2+ and primer continue to participate in the next recycling, resulting in more hairpin probes becoming nickers. The combination of a large number of nickers and FAM-probe resulted in a significant increase in the fluorescence signal of the system, which was attributed to the fact that the double helix DNA was more rigid and separated from the surface of the ultrathin Ti3C2 nanosheets. The obvious fluorescence signal change of the Ti3C2-based Exo III-assisted target recycling can be accurately monitored by fluorescence spectrometry, which is also proportional to the concentration of Hg2+. Under optimum operating conditions, the peak intensity (520 nm wavelength) of fluorescence increased with increasing Hg2+ within a wide dynamic working range from 0.05 nM to 50 nM (R2 = 0.9913) with a limit of detection down to 42.5 pM. The proposed strategy uses ultrathin MXenes as a platform for binding nucleic acids, which contributes to its potential in nucleic acid hybridization-based biosensing and/or nucleic acid signal amplification bio-applications.
研究领域:
分析化学
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环境科学
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纳米技术
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生物传感
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DOI
PubMed
高影响因子
CERAMICS INTERNATIONAL
·
2020
·
IF 3.83
Yi Cui,Meiying Liu,Hongye Huang,Dongao Zhang,Junyu Chen,Liucheng Mao,Naigen Zhou,Fengjie Deng,Xiaoyong Zhang,Yen Wei
Transition-metal carbides, nitrides or carbonitrides (named as MXenes) are a novel type of two-dimensional (2D) materials with the features of traditional 2D materials but more variable chemical compositions. MXenes and related materials have raised more and more research attention and been extensively explored for different applications. In this work, we developed a novel method to synthesize magnetic MXene composites (Ti 3 C 2 -MNPs) for the first time through a one-pot route, which relied on the incorporation of Fe 3 O 4 nanoparticles into Ti 3 C 2 nanosheets via thermal treatment. The potential utilization of these Ti 3 C 2 -MNPs for catalytic degradation of organic dyes through advanced oxidation processes (AOPs) were also evaluated in details. We demonstrated that Fe 3 O 4 nanoparticles with size about 5 nm could be anchored onto Ti 3 C 2 with well dispersed state. The catalytic degradation results demonstrated that Ti 3 C 2 -MNPs possess extremely high degradation efficiency towards different organic dyes under optimal conditions. The electron spin resonance (ESR) spectra identified that both hydroperoxyl radicals (•OH) and superoxide radicals (•O 2 - ) radicals were involved in the degradation process. This work reported a novel one-step method for fabrication MXenes based multifunctional composites, which show extremely high efficiency for AOPs. This method could also be extended for fabrication of many other multifunctional composites for various applications.
研究领域:
材料科学
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环境科学
·
化学工程
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产品关联
DOI
高影响因子
MICROCHIMICA ACTA
·
2021
·Vol. 188
·期 2
·1-12
·
IF 5.833
Hong Juncheng,Wang Wenhai,Wang Jiaqi,Wang Xiao,Xie Hongzhen,Li Tianhua,Gan Ning
A pair of composite probes based on aptamer modified polyhedral oligomeric silsesquioxane-perovskite quantum dots (POSS-PQDs-Apt) as signal probe and titanium carbide (Ti 3 C 2 ) MXenes as quencher were prepared for the first time. They were employed to fabricate one turn-on–type aptasensor relying on fluorescence resonance energy transfer (FRET) for Vibrio parahaemolyticus (VP) determination. The POSS-PQDs-Apt can be adsorbed on the MXenes nanosheets, and its fluorescence was quenched due to the FRET. After the composite probes were incubated with VP for 50 min, the POSS-PQDs-Apt binding with VP can be released from the surface of MXenes, and the signal recovered due to its higher affinity to the VP than MXenes. The fluorescence intensity from 519 nm emission of the system was measured at 480 nm excitation. Under In optimized conditions, the assay can determine VP in the concentration range 10 2 - 10 6 cfu/mL, and the detection limit (LOD) was 30 cfu/mL using fluorescence detection. The LOD is still 100 cfu/mL by naked eye detection which is proper for on-line monitoring VP in aquaculture water. This method was also used to detect VP in actual samples of seawater, the recovery of spiked samples was between 93% and 106%, and relative standard deviation (RSD) was between 2.7% and 6.7%. The result is consistent with the plate count. Therefore, this assay could provide a candidate platform for screening VP in aquaculture industry. Graphical abstract
研究领域:
生物传感器
·
分析化学
·
环境监测
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产品关联
DOI
PubMed
高影响因子
BIOSENSORS & BIOELECTRONICS
·
2021
·
IF 10.618
Yan Sun,Peipei Li,Yu Zhu,Xiaohua Zhu,Youyu Zhang,Meiling Liu,Yang Liu
A sensitive electrogenerated chemiluminescence (ECL) biosensor for glucose was developed based on in situ growth of TiO 2 nanowires on Ti 3 C 2 MXenes (TiO 2 –Ti 3 C 2 ) as the nanoplatform. Via tuning the alkaline oxidation time, different amount of TiO 2 nanowires can be found on MXenes. An ECL biosensor for glucose was constructed by covalent immobilization of glucose oxidase (GODx) on the glycine functional TiO 2 –Ti 3 C 2 surface, with the ECL signal depending on the in-situ formation of H 2 O 2 via the specifically catalysis of glucose by GODx, resulting in the apparent increase of ECL signal. The TiO 2 –Ti 3 C 2 can also act as the catalyst for the oxidation of H 2 O 2 into O 2 to enhance the ECL of luminol. Based on this strategy, a highly sensitive ECL biosensor for glucose was obtained in wide concentration range of 20 nM-12 mM with a low detection limit of 1.2 nM (S/N = 3). The synergistic effects of large surface area, excellent conductivity, and high catalytic activity of the TiO 2 –Ti 3 C 2 make the sensor highly sensitive toward glucose; the specific enzyme catalysis reaction promises excellent selectivity of the ECL sensor. The proposed biosensor has been employed to detect glucose in human serum, fruits, and sweat samples with excellent performance, providing a universal approach for glucose in various samples, which shows great prospect in clinical diagnostics and wearable sensors .
研究领域:
分析化学
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生物传感器
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材料科学
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生物医学工程
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临床诊断
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产品关联
DOI
PubMed
高影响因子
APPLIED SURFACE SCIENCE
·
2024
·
IF 6.3
Jianbo Wan,Ruiqing Wu,Yiyi Chen,Hao Zhang,Huafeng Li,Bohai Wang,Tomasz Liskiewicz,Shengwei Shi
MXenes show great potential in energy storage due to their excellent conductivity, abundant surface groups and adjustable interlayer spacing. Amino modification is an effective strategy to improve electrochemical properties of MXene. However, the selection of amino source is still a key issue. Herein, the amino modification of Ti 3 C 2 MXenes for high-performance supercapacitors has been investigated. The structure and electrochemical properties of Ti 3 C 2 are modified by different amino sources, such as ethylenediamine (EDA), monoethanolamine (MEA) and hydrazine monohydrate (HM). EDA ensures Ti 3 C 2 the largest interlayer spacing (13.96 Å) and highest specific surface area (52.2 m 2 g −1 ). In addition, there are more functional groups in EDA-modified Ti 3 C 2 (EDA-Ti 3 C 2 ) resulted from the stronger electron-donating nature of EDA than HM and MEA. Thus, EDA-Ti 3 C 2 exhibits the largest specific capacitance of 683 F g −1 in 1 M H 2 SO 4 electrolyte at 2 mV/s, and the capacitance maintains 97.3 % of the original after 10,000 cycles at 50 mV/s. As a comparison, MEA-Ti 3 C 2 and HM-Ti 3 C 2 show specific capacitances of 553 F g −1 and 470 F g −1 , respectively. Furthermore, the symmetric supercapacitor based on EDA-Ti 3 C 2 electrode achieves maximum energy density of 7.87 W h kg −1 at power density of 600 W Kg −1 , and the energy density still remains at 6.34 W h Kg −1 even at an increased power density of 3000 W Kg −1 . This study proposes a simple strategy to enhance electrochemical properties of MXene by amino modification, providing valuable insights for high-performance supercapacitors.
研究领域:
材料科学
·
电化学
·
能源存储
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产品关联
DOI
高影响因子
TALANTA
·
2023
·
IF 6.1
Peng Jin,Wenlong Tan,Xu Li,Jinsong Fan,Kun Li
Iodine intake remains a major public health concern, as both iodine excess and deficiency are related to adverse effects on health. Therefore, developing simple and economical methods to detect I − is still in great demand. Herein, we constructed a visual I − sensing platform based on the uncoated Ag–Ti 3 C 2 nanohybrids using methyl orange (MO) as a colorimetric indicator . Plasmonic nanostructures are frequently employed in colorimetric analysis , but uncoated Ag nanoparticles (NPs) are unstable because their surface energies are usually high. Considering that Ag NPs can be etched by I − via forming Ag–I bond, we introduce Ag–Ti 3 C 2 nanohybrids because uncoated Ag NPs with immaculate surfaces are more conducive to binding with I − and being etched. Dissolved O 2 molecules adsorbed on Ti 3+ of Ti 3 C 2 MXenes enable the in situ generation of H 2 O 2 by iodine-etching of uncoated Ag–Ti 3 C 2 nanohybrids. ∙OH radicals promote the degradation of MO through a self-driven Fenton-like process, exhibiting the color variation from orange to transparent. Under optimal conditions, the absorbance of MO at 465 nm decreases linearly with the concentration of I − in the range of 0.5–300 μM, with a limit of detection as low as 0.31 μM. This work opens the feasibility of iodine-etching of Ag in developing novel probes for facile colorimetric determination of I − .
研究领域:
分析化学
·
环境科学
·
公共卫生
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产品关联
DOI
PubMed
高影响因子
JOURNAL OF MATERIALS RESEARCH
·
2023
·Vol. 38
·期 21
·4784-4794
·
IF 2.7
Wang Haoran,Cao Tongtong,Zhou Yicheng,Zhang Jiazheng,Zhang Yuhan,Dong Li,Liu Lin,Zhu Jing,Liu Chao,Tong Zhiwei
A novel electrochemical sensor based on titanium carbide (Ti 3 C 2 ) and cobalt porphyrin (CoTMPyP) nanocomposite was developed to detect catechol (CC). X-ray diffraction (XRD), transmission electron microscopy (TEM), energy-dispersive spectroscopy (EDS), X-ray photoelectron spectroscopy (XPS), and scanning electron microscopy (SEM) methods were used to characterize the CoTMPyP/Ti 3 C 2 nanocomposite and illuminate the electrochemical oxidation process, as well as electrochemical techniques such as electrochemical impedance spectroscopy (EIS), cyclic voltammetry (CV), and differential pulse voltammetry (DPV) were measured. The results indicate that the introduction of CoTMPyP greatly enhanced the electron transfer capability and maintained high stability, good reproducibility, and interference resistance. Moreover, it has a lower detection limit (2.5 μM) in the range of 5–268 μM and has greater application potential in the detection of CC. Hence, Ti 3 C 2 nanocomposites are considered as a candidate material for combination with carbon materials and have potential applications in environmental analysis and catechol detection. Graphical abstract
研究领域:
材料科学
·
环境分析
·
电化学
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产品关联
DOI
高影响因子
ACS Nano
·
2020
·
IF 14.588
Quanquan Guo,Xinxing Zhang,Fengyuan Zhao,Quancheng Song,Gehong Su,Yuxiang Tan,Qingchuan Tao,Tao Zhou,Yanmei Yu,Zehang Zhou,Canhui Lu
Progress toward the integration of electronic sensors with a signal processing system is important for artificial intelligent and smart robotics. It demands mechanically robust, highly sensitive, and self-healable sensing materials which could generate discernible electric variations responding to external stimuli. Here, inspired by the supramolecular interactions of amino acid residues in proteins, we report a self-healable nanostructured Ti3C2MXenes/rubber-based supramolecular elastomer (NMSE) for intelligent sensing. MXene nanoflakes modified with serine through an esterification reaction assemble with an elastomer matrix, constructing delicate dynamic supramolecular hydrogen bonding interfaces. NMSE features desirable recovered toughness (12.34 MJ/m3) and excellent self-healing performance (∼100%) at room temperature. The NMSE-based sensor with high gauge factor (107.43), low strain detection limit (0.1%), and fast responding time (50 ms) can precisely detect subtle human motions (including speech, facial expression, pulse, and heartbeat) and moisture variations even after cut/healing processes. Moreover, NMSE-based sensors integrated with a complete signal process system show great feasibility for speech-controlled motions, which demonstrates promising potential in future wearable electronics and soft intelligent robotics.
研究领域:
材料科学
·
生物仿生学
·
传感器技术
✓ 已验证
DOI
PubMed
高影响因子
ACS Applied Materials & Interfaces
·
2021
·
IF 9.229
Haizhen Liu,Chenglin Lu,Xinchun Wang,Li Xu,Xiantun Huang,Xinhua Wang,Hua Ning,Zhiqiang Lan,Jin Guo
Two-dimensional vanadium carbide (V2C) and titanium carbide (Ti3C2) MXenes were first synthesized by exfoliating V2AlC or Ti3AlC2 and then introduced jointly into magnesium hydride (MgH2) to tailor the hydrogen desorption/absorption performances of MgH2. The as-prepared MgH2–V2C–Ti3C2 composites show much better hydrogen storage performances than pure MgH2. MgH2 with addition of 10 wt % of 2V2C/Ti3C2 initiates hydrogen desorption at around 180 °C; 5.1 wt % of hydrogen was desorbed within 60 min at 225 °C, while 5.8 wt % was desorbed within 2 min at 300 °C. Under 6 MPa H2, the dehydrided MgH2–2V2C/Ti3C2 can start to recover hydrogen at room temperature, and 5.1 wt % of H2 is obtained within 20 s at a constant temperature of 40 °C. The reversible capacity (6.3 wt %) does not decline for up to 10 cycles, which shows excellent cycling stability. The addition of 2V2C/Ti3C2 can remarkably lower the activation energy for the hydrogen desorption reaction of MgH2 by 37% and slightly reduce the hydrogen desorption reaction enthalpy by 2 kJ mol–1 H2. It was demonstrated that the combination of V2C and Ti3C2 promotes the hydrogen-releasing process of MgH2 compared with addition of only V2C or Ti3C2, while Ti3C2 impacts MgH2 more significantly than V2C in the hydrogen absorption process of MgH2 at ambient temperatures. A possible mechanism in the hydrogen release and uptake of the MgH2–V2C–Ti3C2 system was proposed as follows: hydrogen atoms or molecules may preferentially transfer through the MgH2/V2C/Ti3C2 triple-grain boundaries during the desorption process and through the Mg/Ti3C2 interfaces during the absorption process. Microstructure studies indicated that V2C and Ti3C2 mainly act as efficient catalysts for MgH2. This work provides an insight into the hydrogen storage behaviors and mechanisms of MgH2 boosted by a combination of two MXenes.
研究领域:
材料科学
·
能源存储
✓ 已验证
DOI
PubMed
高影响因子
Journal of Materials Chemistry C
·
2017
·Vol. 5
·期 16
·4068-4074
·
IF 5.256
Xinliang Li,Xiaowei Yin,Meikang Han,Changqing Song,Hailong Xu,Zexin Hou,Litong Zhang,Laifei Cheng
Ti3C2Tx MXenes modified with in situ grown carbon nanotubes (CNTs) are fabricated via a simple catalytic chemical vapor deposition (CVD) process. The as-prepared Ti3C2Tx/CNT nanocomposites show that one-dimensional (1D) carbon nanotubes are uniformly distributed in the interlayers of two-dimensional (2D) Ti3C2Tx MXene flakes. Compared with the pristine Ti3C2Tx MXenes, the hierarchical sandwich microstructure makes a contribution to the excellent electromagnetic wave absorption performance in the frequency range of 2–18 GHz, including higher absorption intensity (the minimum reflection coefficient reaches −52.9 dB, ∼99.999% absorption), broader effective absorption bandwidth (4.46 GHz), lower filler loading (35 wt%) and thinner thickness (only 1.55 mm). In addition, with the adjustment of thickness from 1.55 to 5 mm, the effective absorption bandwidth can reach up to 14.54 GHz (3.46–18 GHz). Different absorption mechanisms mainly based on polarization behaviors and conductivity loss are discussed. This work not only proposes the design of a novel electromagnetic wave absorber, but also provides an effective route for extending further the applications of 2D MXene materials in the field of electromagnetic wave absorption.
研究领域:
材料科学
·
电磁学
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产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）