JOURNAL OF MATERIALS SCIENCE
·
2023
·Vol. 58
·期 15
·6743-6756
·
IF 4.5
Zhou Huan,Wang Jie,Yang Bing,Sun Manna,Liang Chunyong,Yang Lei,Zhao Xiaoyan,Wang Hongshui
In this work, near-infrared light responsive upconversion nanoparticles TiO 2 /(Ca,Y)F 2 :Tm,Yb were hydrothermally prepared for tumor control. Moreover, femtosecond laser was adopted to reduce particle size and aggregation of TiO 2 /(Ca,Y)F 2 :Tm,Yb, as a strategy to enhance its dispersity. In vitro studies of the biocompatibility and tumor control efficacy of TiO 2 /(Ca,Y)F 2 :Tm,Yb were carried out via co-culturing human pancreatic carcinoma cells (CFPAC-1). It was found in the absence of near-infrared light, TiO 2 /(Ca,Y)F 2 :Tm,Yb showed no toxicity to CFPAC-1 cells. On contrast, when exposed to near-infrared light, particles exhibited irradiation time, irradiation interval and particle concentration dependent suppression of CFPAC-1 cells proliferation along with portion of S phase cells increase. A nude mouse model with CFPAC-1 cells injection was established and TiO 2 /(Ca,Y)F 2 :Tm,Yb was subsequently applied for in vivo tumor control. A 15 days tracking confirmed the antitumor capability of near-infrared light excited TiO 2 /(Ca,Y)F 2 :Tm,Yb. Overall, we anticipate that the here-introduced TiO 2 /(Ca,Y)F 2 :Tm,Yb can serve as an effective agent for photodynamic antitumor therapy. Graphical Abstract
研究领域:
纳米技术
·
生物医学工程
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癌症研究
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光动力治疗
·
材料科学
✓ 已验证
产品关联
DOI
高影响因子
OPTICAL MATERIALS
·
2023
·
IF 3.9
Xiaoyan Zhao,Yongcheng Zhou,Hua Guo,Yuqi Zhai,Xianrui Zou,Donghui Wang
Titanium dioxide (TiO 2 ) has received widespread attention as high stability, low toxicity and costless photocatalyst , but it only exhibits photocatalytic activity under ultraviolet (UV) light. To improve TiO 2 photocatalytic efficiency, Bio-CaCO 3 /WO 3 /TiO 2 /(Ca,Y)F 2 :Tm,Yb was prepared. TiO 2 was combined with upconversion materials, coupled with WO 3 and loaded on oyster shell powder (Bio-CaCO 3 ), which showed that the prepared photocatalyst effectively reduce the band gap of TiO 2 , expand the photoreaction range of the material and avoid agglomeration, thus improving its photocatalytic efficiency and antibacterial efficiency. The photocatalytic degradation efficiency of Bio-CaCO 3 /WO 3 /TiO 2 /(Ca,Y)F 2 :Tm,Yb (50 mg) was 24.32% higher than that of TiO 2 /(Ca,Y)F 2 :Tm,Yb in 90 min. And its antibacterial rates against Escherichia coli ( E. coli ) and Staphylococcus aureus ( S. aureus ) were enhanced by 38.68% and 25.89% compared to TiO 2 /(Ca,Y)F 2 :Tm,Yb, respectively.
研究领域:
材料科学
·
环境科学
·
生物学
✓ 已验证
产品关联
DOI
高影响因子
RARE METALS
·
2021
·Vol. 41
·期 2
·650-662
·
IF 4.003
Guo Hua,Li Jun,Zou Xian-Rui,Wang Hong-Shui,Kang An,Zhou Huan,Li Ming-Jun,Zhao Xiao-Yan
Abstract Development of photocatalytic materials able to profit from the whole spectrum of sun for efficient organic pollution removal and bacterial elimination is a fascinating strategy in environmental engineering. In current work, GO-TiO 2 /(Ca,Y)F 2 :Tm,Yb, a full-spectrum composite photocatalyst, was prepared via hydrothermal processing with TiO 2 /(Ca,Y)F 2 :Tm,Yb particles deposited on the surface of graphene oxide (GO). The surface properties of GO-TiO 2 /(Ca,Y)F 2 :Tm,Yb were characterized using various characterization techniques including X-ray diffraction (XRD), scanning electron microscopy (SEM), X-ray photoelectron spectroscopy (XPS) and Brunauer–Emmett–Teller (BET) surface area analyzer. Besides, ultraviolet–visible (UV–Vis) diffuse reflectance spectroscopy, electron spin resonance (ESR) and other methods were used to systematically explore the photocatalytic mechanism of GO enhancement of TiO 2 /(Ca,Y)F 2 :Tm,Yb. In photocatalytic degradation study, the degradation rate of methyl orange (MO) was improved by 40% when GO was added into the TiO 2 /(Ca,Y)F 2 :Tm,Yb system. In addition, the presence of GO also improves the antibacterial ability of TiO 2 /(Ca,Y)F 2 :Tm,Yb against Escherichia coli and Staphylococcus aureus . All results reveal high efficacy of GO-TiO 2 /(Ca,Y)F 2 :Tm,Yb under full spectrum light irradiation, in which (Ca,Y)F 2 :Tm,Yb and TiO 2 can improve its utilization of full spectrum sunlight, and GO can enhance adsorption ability of dye and electron–hole pair differentiation ability of TiO 2 /(Ca,Y)F 2 :Tm,Yb. Graphic abstract
研究领域:
环境工程
·
材料科学
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）