Magnesium-Mediated Umpolung Carboxylation of p-Quinone Methides with CO2
Magnesium-mediated reductive carboxylation of p-QMs with CO2 via an Umpolung strategy has been developed, which can be used for the preparation of various aryl acetic acids. This protocol featured high atom economy, mild conditions, and operational simplicity. The creation of this Umpolung carboxylation of p-QMs will unprecedentedly extend the application of p-QMs to nucleophilic reagents.
研究领域:
有机化学
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环境化学
✓ 已验证
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）