A One-pot Green Synthesis of Alkylidenesuccinimides
A mild and facile Wittig reaction between N -substituted maleimides and aldehydes has been developed. Various synthetically valuable alkylidenesuccinimides were obtained from this one-pot reaction in high yields (up to 99%). The product was obtained by simple filtration and no extra purification was necessary. Ethanol, an environment-benign solvent, was found to be a suitable reaction medium.
研究领域:
有机化学
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药物化学
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绿色化学
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合成方法学
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medicinal chemistry
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DOI
高影响因子
危险品化学品经营许可证（带存储）