Aijuan Xie,Linghui Cao,Tianyu Shen,Yuanxinyi Zhou,Haoye Wang,Shiping Luo
As para -aminophenol (PAP) is toxic to humans, causing skin irritation, eye damage, and central nervous system depression, and it can form as a degradation product of paracetamol (PAT) under certain conditions, the simultaneous determination of PAP and PAT is crucial. This work presents the fabrication of three-dimensional ZnCo 2 O 4 @Fe 3 O 4 /MWCNTs hybrid for the simultaneous determination of PAP and PAT using ZIF-8/67@Fe 3 O 4 as precursor and MWCNTs as conductive substrate. The ZnCo 2 O 4 @Fe 3 O 4 /MWCNTs/GCE sensor exhibits linear ranges 1.0–150.0 μM with detection limits of 0.033 μM and 0.018 μM for PAP and PAT, respectively. The developed sensor was successfully used for the determination of PAP and PAT in acetaminophen tablets and lake water with satisfactory results.
Multifunctional cotton fabric holds significant promise for domestic and healthcare applications. A key challenge remains developing sustainable fabrication routes for mechanically durable cotton textiles integrating intrinsic and photothermally amplified antibacterial functions. Herein, we prepared ZIF-8/67-loaded Ag nanoparticles on cotton fabric using in-situ reduction technology (ZIF-8/67-Ag@CCT). Subsequent dip-coating with polydimethylsiloxane (PDMS) produced ZIF-8/67-Ag@CCT@PDMS, enhancing superhydrophobicity. The modified fabric exhibited exceptional superhydrophobicity (water contact angle: 148.55 ± 0.21°) and UV-blocking capabilities (UPF value: 186). The surface demonstrated excellent self-cleaning properties against dyes and maintained robust stability after 30 washing cycles and immersion in acidic/alkaline solutions (>97.0% antibacterial efficacy retention). Critically, the fabric exhibited excellent biocompatibility, as validated by human induced pluripotent stem cell-derived skin organoid assays showing no adverse effects on cell proliferation, apoptosis, or survival rates. Antibacterial effects originated from the penetration of AgNPs and Ag⁺/Zn²⁺/Co²⁺ ions into bacterial structures, disrupting metabolism via reactive oxygen species (ROS) generation. The multifunctional ZIF-8/67-Ag@CCT@PDMS fabric presents a highly promising solution for durable antibacterial medical textiles, offering combined antibacterial activity, exceptional stability, self-cleaning, UV resistance, and biocompatibility.
危险品化学品经营许可证（带存储）