Nano Today
·
2025
·
IF 10.9
Kecheng Quan,Yupu Lu,Ting Zhang,Shuren Wang,Hao Tang,Chunhao Yu,Yongsheng Zhou,Yunsong Liu,Dandan Xia,Yufeng Zheng
Antimicrobial coatings with the capabilities to prevent and treat biofilm infections on implant are promising surface treatment strategies, but it is difficult to eradicate an already-formed biofilm by the coating. Magnetically-drivable coatings can physically destruct the surface-attached biofilm to enhance antimicrobial killing. However, current magnetic coatings cannot inhibit the initial bacteria growth and the demand of coating stability restricts their magnetic controllability. Herein, a magnetically-drivable, pH-responsive coating is developed by simply mixing Fe 3 O 4 and ZIF-8 nanoparticles on titanium surface. In physiological pH, Fe 3 O 4 nanoparticles are stable and non-magnetically drivable on surface due to charge attractions and electrostatic interactions. While in acidic pH caused by bacterial growth, ZIF-8 degradation is significantly accelerated, releasing Zn 2 + and recovering the magnetic controllability of Fe 3 O 4 nanoparticles. The released Zn 2+ kills the initially-attached bacteria, inhibiting subsequent biofilm formation. Once a biofilm has formed, Fe 3 O 4 nanoparticles can be magnetically pulled-off to destruct the biofilm structure and then enhance antibiotic killing. The Fe 3 O 4 /ZIF-8 coating shows excellent biocompatibility and osteogenesis to compare with bare Ti disc. Animal experiments further proved the in-vivo antimicrobial and osteogenic performances of the coating. Therefore, this work put forward a new surface strategy to solve biofilm-related infections on implants.
研究领域:
生物材料学
·
医学工程
·
微生物学
✓ 已验证
产品关联
DOI
高影响因子
Water Cycle
·
2025
·
IF 8.7
Xiaobin Zhou,Chenyu Zhou,Min Huang,Yingxue Wang,Mengxin Zhao,Yanan Zhang,Yinming Fan,Yinian Zhu,Zongqiang Zhu
Nano zero-valent iron (nZVI) has garnered significant attention as an excellent environmental remediation material for Cr(Ⅵ) adsorption. However, its practical utilization is significantly impeded by inherent limitations, notably its propensity for aggregation and susceptibility to oxidation. This study proposed an innovative approach that using zeolite imidazole framework-8 (ZIF-8) as a cladding material for encapsulating nZVI particles. This encapsulation served to safeguard nZVI from oxidation and agglomeration. Furthermore, the ZIF-8 coating possessed suitable pore channels, allowing the migration of Cr(VI) ions towards the nZVI’s surface, thereby enabling efficient reduction. The ZIF-8-coated nZVI composite (ZIF-8@nZVI) achieved a remarkable Cr(VI) removal efficiency of 98.43% under the optimized conditions. After 10 days of exposure in the aqueous solution, the efficiency remained above 84%. The uptake of Cr(VI) by ZIF-8@nZVI proceeded via a chemisorption pathway, inherently spontaneous and endothermic in character. The mechanism analysis indicated that ZIF-8 and nZVI exhibited synergistic enhancement effect on Cr(VI) removal. The protonated nitrogen groups within ZIF-8 facilitated the swift diffusion of negatively charged Cr(VI) ions to the surface of ZIF-8@nZVI. Once adsorbed, Cr(VI) was directly reduced to Cr(III) by Fe 0 , which in turn underwent oxidation to Fe(II)/Fe(III). Notably, Fe(II) indirectly reduced Cr(VI) to Cr(III), while itself being oxidized to Fe(III). Consequently, the resulting Cr(III) ions co-precipitated with Fe(III), forming hydroxide complexes that were eliminated from the aqueous environment. Overall, this research demonstrated the practicability of employing ZIF-8 as a coating material to develop highly efficient nZVI-based adsorbents and highlighted the potential of ZIF-8@nZVI in addressing Cr(VI) contamination challenges.
研究领域:
环境修复
·
材料科学
·
化学工程
✓ 已验证
产品关联
DOI
高影响因子
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
·
2024
·
IF 4.9
Yongwei Cai,Yao Chen,Ruru Wang,Jianxiang Li,Hong Yang,Yuanju Li,Danni Qu
Developing a superhydrophilic/underwater oleophobic mesh membrane using an economical and eco-friendly method is still challenging to achieve high efficiency for oily wastewater separation. In this study, we proposed a novel approach to fabricate superhydrophilic/underwater oleophobic PVP/ZIF-8 coatings on stainless steel (SS) mesh using a low-cost and environmentally friendly electrodeposition method. The prepared PVP/ZIF-8@SS mesh membrane exhibited remarkable self-cleaning and anti-oil-fouling properties, along with a strong chemical robustness in extreme environments. Additionally, the mesh membrane demonstrated strong antimicrobial ability and excellent corrosion resistance property. The mesh membrane also showed promising potential in gravitational oil-water separation and oil recovery, achieving a separation efficiency of 99.0% and a water flux of 3.8 × 10 3 L·m −2 ·h −1 for rapeseed oil-water mixtures. Importantly, the PVP/ZIF-8@SS mesh membrane maintained exceptional separation efficiency, high water flux, and underwater oleophobicity properties even after undergoing 35 cycles of oil-water separations. The oil-water separation mechanism of the PVP/ZIF-8@SS mesh membrane suggested that the surface of the mesh membrane contained PVP/ZIF-8 particles with a significant negative charge. These particles preferentially interacted with positively charged water, facilitating the rapid passage of water phase through the pores, while impeding the permeation of negatively charged oil phase. This research provides an effective strategy for practical applications, including marine oil spill cleanup, oily wastewater treatment, and recycling of residual cooking oil in the restaurant industry.
研究领域:
材料科学
·
环境工程
✓ 已验证
产品关联
DOI
高影响因子
ACS Omega
·
2022
·
IF 4.132
Xiaoqiang Zhang,Shuoshuo Yang,Ruofei Lu,Xingjie Zan,Na Li
Anchoring metal–organic framework (MOF) coating has attracted extensive interest due to its wide applications in drug delivery, gas storage and separation, catalysis, and so forth. Here, we reported a flexible strategy on generating ZIF-8 coatings onto diverse substrates in the scale up to hundreds cm2, independent of the geometry of the substrate, with controllable thickness, texture structure, and crystal size of coating. By understanding the mechanism and factors on the formation of ZIF-8 coatings, various zeolitic imidazolate framework coatings were successfully produced. This general strategy and in-depth insights pave the new highway to the design and synthesis of MOF coatings onto diverse substrates.
研究领域:
材料科学
·
化学工程
✓ 已验证
产品关联
DOI
PubMed
高影响因子
TALANTA
·
2016
·
IF 4.035
Jie Huang,Changrong Ou,Fangying Lv,Yuting Cao,Haiqing Tang,You Zhou,Ning Gan
Some harmful aliphatic diamines, e.g., putrescine (Put) and cadaverine (Cad), play important roles in food safety evaluation. In this study, we proposed on-fiber derivatization solid-phase microextraction analysis of non-volatile aliphatic diamines in fish using zeolitic imidazolate framework 8 (ZIF-8) as a solid-phase microextraction (SPME) coating. It was employed to encapsulate isobutyl chloroformate (IBCF, 40 °C, 15 min) for aqueous extraction of Put and Cad. After that, the derivatized aliphatic amines were thermally desorbed in the GC injection port and analyzed by GC-MS. The porous and hydrophobic ZIF-8 with high surface area can increase the IBCF loading amount and prevent it from decomposing, thus increasing the amine extraction effectiveness and sensitivity. In SIM mode and using the molecular ion for quantification, the limits of detection for Put and Cad were 27.1 and 33.2 μg L −1 , respectively under the optimal conditions. The fiber-to-fiber reproducibility values (RSDs) for three ZIF-8 coated fibers were less than 11.4% for both Put and Cad. The extraction with the new fiber was reproducible for at least 30 cycles without a noticeable decrease of performance (RSD<10%). The new fiber was successfully applied to the detection of putrescine and cadaverine in several fish samples and showed good recoveries (78.6–104%).
研究领域:
食品科学
·
分析化学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Chem
·
2023
·
IF 23.5
Xinyu Liu,Ziwei Ye,Qian Xiang,Zehong Xu,Wenhui Yue,Chunchun Li,Yikai Xu,Lingzhi Wang,Xiaoming Cao,Jinlong Zhang
Surface-enhanced Raman spectroscopy (SERS) is a powerful technique that has found applications in many research fields. As promising alternatives to the current most popular plasmonic metal SERS substrates, semiconductor SERS substrates have many appealing attributes. However, they permit signal enhancement only to analytes adsorbed chemically on their surface, which means that semiconductor-based SERS can only be used for studying model analytes such as dyes or thiols. Using volatile organic compounds (VOCs) as an example, we demonstrate for the first time the detection of non-adsorbing analytes on ZnO nanoparticles. Specifically, this was achieved by coating ZnO nanoparticles with ZIF-8 shells, which enriches VOC molecules and dampens the decay of the electromagnetic field around their surface, thereby significantly boosting their electromagnetic enhancing capability such that it permits signal enhancement for non-adsorbing analytes. Importantly, the MOF-coating strategy is universal, which means that it may enable the detection of a wider variety of non-adsorbing analytes where conventional semiconductor-based SERS fails.
研究领域:
材料科学
·
光谱学
✓ 已验证
DOI
高影响因子
Nanoscale
·
2025
·
IF 5.1
Yongcheng Li,Dajian Li,Yuhong Zheng,Sirui Lu,Yuepeng Cai,Renfeng Dong
Wastewater treatment is a key component in maintaining environmental health and sustainable urban life, and the rapid development of micro/nanotechnology has opened up new avenues for more efficient treatment processes. This work developed a novel biohybrid microrobot for the efficient adsorption of a series of organic pollutants in water—the microrobot with a biodegradable Spirulina skeleton and biocompatible ZIF-8 skin. The microrobot not only has a low-cost and simple preparation method but also shows attractive propulsion in various contaminant solutions (including rhodamine B, methylene blue, and methyl orange) under a low-intensity (3 mT) rotating magnetic field and has excellent directional control. Our research results show that the biohybrid microrobot can significantly improve the adsorption performance of various organic pollutants in the moving state, thereby improving the purification rate. In addition, the microrobot also has good swarming motion control to achieve directional and efficient adsorption of organic pollutants in the microspace. Such Spirulina@ZIF-8 microrobots can be prepared in large quantities as highly controllable, biocompatible, and wireless tools, showing great potential for water treatment.
研究领域:
环境科学
·
材料科学
·
生物学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2019
·
IF 8.355
De Zhao,Zhihua Wu,Jian Yu,Hongzhi Wang,Yaogang Li,Yourong Duan
In this work, a synergetic fluorescence enhancement strategy based on micro/nanostructure optimization of ZnO nanorod arrays and in situ ZIF-8 coating was proposed for the highly sensitive microfluidic detection of carcinoembryonic antigen (CEA). The glass capillary was chosen as the microfluidic channel, and controllable construction of ZnO nanorod arrays on the inner wall of the microchannel was conducted via the intermittent reaction method. Additionally, the application of the optimal ZnO nanorod array to glass capillary-based microfluidic fluorescence detection was demonstrated. The fluorescence enhancement characteristic of the zeolitic imidazolate framework-8 (ZIF-8) towards organic fluorescence labels were investigated and successfully applied to protein marker detection. After formation of sandwich immunoassay on the ZnO/PAA nanorod arrays, the in situ ZIF-8 coating via a moderate chemical method could significantly improve the fluorescence intensity of fluorescent labels via direct contact. In CEA detection, the limit of detection (LOD) reached as low as 0.01 pg mL −1 , and the dynamic range was 0.01 pg mL −1 to 100 pg mL −1 . Hence, the microfluidic fluorescence detection strategy based on the ZnO nanorod arrays/PAA layers/ZIF-8 coating with a synergetic fluorescence enhancement effect provides a superior, promising, and highly sensitive approach for the detection of protein markers, including CEA.
研究领域:
生物化学
·
分析化学
·
纳米技术
·
生物传感器
·
癌症诊断
✓ 已验证
产品关联
DOI
高影响因子
ADVANCED FUNCTIONAL MATERIALS
·
2024
·
IF 18.5
Shiyuan Liang,Liyuan Chen,Cong Liu,Bowen Guo,Yijie Fan,Zhou Li,Yan Liu,Dan Luo
Antioxidant enzymes are considered to be the most direct and safe candidates to effectively resist oxidative stress and treat senile osteoporosis. However, due to their size, existing enzyme delivery carriers are inevitably endocytosed by cells and subsequently enter endosomes/lysosomes with low pH and rich in acid hydrolase, resulting in the limited therapeutic effects. In this work, an ultrasmall superoxide dismutase (SOD) nanoformulation reinforced with ultrathin ZIF-8 coating (utZIF-SOD) via in situ coordination-mediated self-assembly strategy is constructed. Notably, utZIF-SOD achieves direct, efficient cellular uptake mediated by small size effect, thereby avoiding lysosomal degradation. In particular, ultrathin ZIF-8 coating strengthened the stability of enzyme. Even in aged cells with high oxidative stress levels, utZIF-SOD maintained excellent stability, and its efficiency in scavenging excess intracellular reactive oxygen species (ROS) is ≈1.5 times that of native SOD, better promoting the osteogenic differentiation of aged bone marrow mesenchymal stem cells. In a senile osteoporosis mouse model, the bone mineral density increment after treatment with utZIF-SOD is ≈2 times that of native SOD, achieving the reversal of senile osteoporosis. This work demonstrates the great promise in the synthesis of ultrasmall nanoformulations with ultrathin metal-organic framework coating and opens new avenues for efficient enzyme delivery.
研究领域:
纳米技术
·
生物医学工程
·
药学
·
老年学
·
细胞生物学
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）