ADVANCED FUNCTIONAL MATERIALS
·
2019
·Vol. 29
·期 23
·1901026
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IF 15.621
Weiran Zhou,Dan Li,Zhengguo Xiao,Zhilin Wen,Mengmeng Zhang,Wanpei Hu,Xiaojun Wu,Mingtai Wang,Wen-Hua Zhang,Yalin Lu,Shihe Yang,Shangfeng Yang
The organic–inorganic halide CH 3 NH 3 PbI 3 (MAPbI 3 ) has been the most commonly used light absorber layer of perovskite solar cells (PSCs); however, solution-processed MAPbI 3 films usually suffer from random crystal orientation and high trap density, resulting in inferior power conversion efficiency (PCE) with open circuit voltage ( V oc ) being typically below 1.2 V for PSC devices. Herein, for the first time an imidazole sulfonate zwitterion, 4-(1H-imidazol-3-ium-3-yl)butane-1-sulfonate (IMS), is applied as a bifunctional additive in regular-structure planar heterojunction PSC devices to regulate the crystal orientation, yielding highly ordered MAPbI 3 film and passivating the trap states of the film. Such a dual effect of IMS is fulfilled via coordination interactions between the sulfonate moiety of IMS with the Pb2 + ion and the electrostatic interaction between the imidazole of IMS with the I – ion of MAPbI 3 . As a result, under a optimized IMS doping ratio of 0.5 wt%, the PSC device exhibits a significant increase in PCE from 18.77% to 20.84%, with suppressed current–voltage hysteresis and promoted ambient stability. Moreover, a high V oc of 1.208 V is achieved under a higher IMS doping ratio of 1.2 wt%, which is the highest V oc for regular-structure MAPbI 3 planar PSC devices based on TiO 2 electron transport layer.
研究领域:
材料科学
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能源研究
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SEPARATION AND PURIFICATION TECHNOLOGY
·
2020
·
IF 5.774
Noor Ul Afsar,Xiaolin Ge,Zhang Zhao,Arif Hussain,Yubin He,Liang Ge,Tongwen Xu
Lithium extraction from saline water by electrodialysis is an energy-efficient process. Herein, we examined a synergetic impact of amino isophthalic acid (AIPA) and the fixed quaternized groups to produce stable, cost-effective, and efficient zwitterion membranes (ZIMs) via a sol-gel process. We developed different membranes such as QAIPA-10, QAIPA-15, and QAIPA-20 by varying the amount of AIPA from 10 to 20 wt% in the base membrane. It was found that when the amount of AIPA increases, the Li + flux also improved from 1.66 × 10 −10 mol cm −2 s −1 to 33.46 × 10 −10 mol cm −2 s −1 , respectively. By comparing the membranes based on the various amounts of AIPA, the membrane with 20 wt% (QAIPA-20) had a higher Li + flux and reasonable permselectivity due to the high WU, CEC as compared with the QAIPA-10, QAIPA-15 and base membranes. To further explore the performance of the QAIPA-20, we also studied various cation systems such as Na + /Mg 2+ , K + /Mg 2+ , and H + /Fe 2+ , respectively. The obtained results proved that AIPA strongly dictates the cation transport channels, hydrophilicity, and repulsive centers of the ZIMs. We may conclude that QAIPA-20 is effective for lithium extraction, water desalination, and acid recovery.
研究领域:
材料科学
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环境工程
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化学工程
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Nature Communications
·
2026
·
IF 18.1
Peng Haibao,Zeng Youming,Huang Yang,Lin Chenyu,Lei Zeyu,Sun Peixin,Yang Jiahui,Sheng Shaoqi,Huang Yuxin,Li Xiaohui,Zhao Jiaxu,Zeng Rui,Li Cheng,Yang Wanqi,Di Xiangjie,He Sisi,Wang Yongsheng,Yang Hanting,Yang Wuli,Chi Yudan
The central nervous system is a critical reservoir for cancer metastasis, underscoring the urgent need for effective strategies for targeted drug delivery that minimize systemic side effects. Here, we present a zwitterionic polycarboxybetaine (PCB) designed to achieve selective accumulation within the tumor vasculature of brain metastases, thereby facilitating the rapid release of therapeutics without relying on external stimuli in preclinical models. PCB selectively targets the betaine-γ-aminobutyric acid transporter 1 (BGT1) at the blood-brain-tumor barrier (BBTB), enabling localized enrichment of nanoparticles within the tumor vasculature. The intrinsic mechanical flexibility of PCB activates the Piezo1 ion channel in endothelial cells, resulting in calcium ion influx and enhanced calpain activity, which together facilitate the degradation of VE-cadherin. The burst-release mechanism improves vascular permeability and compromises the integrity of the tumor vascular barrier, allowing for the swift release of encapsulated therapeutics and promoting extensive drug distribution within the tumor microenvironment. Notably, PCB encapsulating either osimertinib or cisplatin demonstrates therapeutic efficacy, intratumoral targeting, and favorable biological safety in disease models. These findings indicate that this zwitterion-functionalized platform effectively surmounts the challenges posed by the BBTB, supporting improved drug delivery and therapeutic efficacy in brain metastases.
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高影响因子
Nature Communications
·
2025
·Vol. 16
·期 1
·1-14
·
IF 15.7
Wang Yonglin,Cui Yangfeng,Zhao Meiqi,Wang Jiazhi,Liu Xueqin,Zhu Yunhai,Yang Yingkui
Aqueous zinc-iodine (Zn||I 2 ) batteries, recognized for their cost-effectiveness, safety, and environmental sustainability, are emerging as the next-generation energy storage technologies. However, capacity degradation arising from the detrimental parasitic reactions at both the negative electrode and positive electrode interfaces presents substantial challenges for the practical implementations of Zn||I 2 batteries. Herein, we develop zwitterion-mediated interface chemistry to modulate the interface reactions using the zwitterion of 1-butylsulfonate-3-methylimidazolium (BM) as an electrolyte additive. At the negative electrode, the alignment of electric field-oriented BM molecules creates a dynamic dual-asymmetry interface, facilitating homogeneous Zn deposition and protecting the Zn metal electrode from the water and corrosive polyiodides. At the positive electrode, the reconfigured solvation configuration of iodide ions, involved by BM molecules, deactivates the interface reaction associated with the I 2 dissolution and polyiodide formation. Consequently, Zn||I 2 batteries with BM additive demonstrate enhanced rate capability (135.5 mAh g −1 at 20.0 A g −1 ) and extended durability (capacity retention of 91.9% after 50,000 cycles at 10.0 A g −1 ). The zwitterion-mediated interface chemistry effectively tackles the insurmountable challenges of aqueous Zn||I 2 batteries, facilitating their reliable and practical implementation.
研究领域:
储能
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电化学
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材料科学
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电池技术
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Materials Today Bio
·
2023
·
IF 8.2
Anning Chen,Zhengao Wang,Hailun Chen,Bo Pang,He Cai,Ziheng Chen,Chengyun Ning,Dong Ma,Jie Tang,Hongzheng Zhang
The cochlear implant (CI), an advanced electronic device replacing the entire cochlear function, is the ultimate treatment for over 466 million people with disabling hearing loss. Infection after cochlear implantation is a common and worrisome complication despite the routine administration of the antibiotic. The bacterial biofilms formed on the surface of CI are the main cause of antibiotic failure. To solve this problem, we developed a copper-containing zwitterionic coating consisting of anti-adherent poly sulfobetaine methacrylate (PSB) and steadfast polydopamine (PDA). CuSO 4 /H 2 O 2. was added to accelerate this co-deposition reaction and enhance the anti-bacterial property. The preparation method was simple, rapid, and suitable for clinical use. In our in vitro and in vivo studies, the PSB/PDA(Cu) coating showed high biocompatibility, and conferred CI implants excellent anti-inflammatory, strong anti-bacterial effects, and great anti-biofilm properties to representative Gram-positive and Gram-negative bacteria. These findings implied that the PSB/PDA(Cu) coating was a unique anti-bacterial strategy for enhancing CI performance.
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JOURNAL OF APPLIED POLYMER SCIENCE
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2021
·Vol. 139
·期 7
·51648
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IF 3.125
Huan Ding,Shouping Xu,Jiangjiang Wang,Zhouxiang Fan,Zhongquan Huang,Hui Wu,Pihui Pi,Jiang Cheng,Xiufang Wen
This paper proposes a cationic double-network hydrogel, which has good electrical conductivity, antibacterial properties, antiprotein adsorption, and mechanical properties. The cationic polymer formed a conductive path in the hydrogel network, so that the gel had good conductivity. With the increase of carboxybetaine ester, the conductivity gradually increases. As a sensor, hydrogel could respond quickly to strains such as stretching and bending. In addition, the hydrogel showed excellent antibacterial properties against Escherichia coli , the antibacterial rate can reach up to 99%. After hydrolysis, the hydrogel showed stable antiprotein adsorption performance. The tensile strength of the gel could reach 1.05 MPa, and the elongation at break was 474.31%. Therefore, this gel may be used for dressing and electronic skin. And the morphology of the hydrogel was characterized by FT-IR, X-ray diffraction, and SEM.
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Journal of the American Chemical Society
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2025
·
IF 15.6
Jianxiang Wu,Yuxin Chen,Wei Du,Yaming Hao,Shaoyan Wang,Ran Wang,Shuangshuang Cha,Xuejing Yang,Chang Yan,Cheng Lian,Honglai Liu,Ming Gong
The electrode/electrolyte interfacial structure is a seminal component that governs the activity of electrocatalytic water splitting, providing alternative approaches to electrocatalyst design. Herein, we demonstrate that a dense interface constituting of zwitterionic betaine could selectively accelerate the alkaline oxygen evolution reaction (OER) by 2 orders of magnitude in current. The hygroscopic betaine molecules not only bind water molecules strongly but also endow the underhydrated characteristics of the hydroxide anions that increase their activity coefficient. The underhydrated hydroxide anions can also be enriched within the inner Helmholtz plane, which forms the mixed hydroxide anion-betaine adsorbate layer that significantly increases the effective potential that drives the OER. This interface can further segregate the reactive zones to selectively promote hydroxide oxidation and retard the oxidative polymerization of neutral anilines for improving the durability by at least an order of magnitude, creating new possibilities for impure water electrolysis.
研究领域:
电化学
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催化
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材料科学
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表面科学
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能量转换
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物理化学
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Surfaces and Interfaces
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2026
·
IF 6
Tiangang Xu,Shuxue Zhou
Zwitterions were grafted to silicate networks by co-condensation using SBSi. • High hydrophilicity was achieved based on LK23 silicate and 15 wt% SBSi. • Optimized coating exhibited anti-oil performance under both wet and dry conditions. • Coating removed viscous oils and residues by simple water rinsing or immersion. • Coating showed excellent antifogging performance under varied fogging conditions. The development of anti-oil-fouling coatings is vital for applications ranging from industrial equipment to domestic kitchen appliances. In this study, anti-oil/antifogging coatings were fabricated by grafting zwitterions to silicate networks through the co-condensation of a sulfobetaine zwitterionic siloxane with silicate. Effects of the composition of silicate coatings, the content of zwitterions on the surface hydrophilicity, optical properties, durability of hydrophilicity, and anti-oil/antifogging performance of coatings were systematically investigated. Introduction of zwitterions favored the coating compactness as well as the enhanced surface hydrophilicity. Importantly, the ratio of lithium silicate-to-potassium silicate strongly influences the durability of hydrophilicity. High surface hydrophilicity, i.e., water contact angle below 10°, could be well maintained at 2:3 of lithium silicate-to-potassium silicate mass ratio even after 168 h of water immersion. The optimized zwitterion-bearing coating reduced the underwater oil adhesion force from 8.8 μN to 0.5 μN, confirming outstanding underwater anti-oil capability. More interestingly, the coating rapidly and completely detached viscous vegetable oil and oil fumes adhered under dry conditions through simple water rinsing or immersion. The coating also exhibited outstanding anti-fogging performance under wide spectrum of conditions. After 1000 cycles of steel wool abrasion, the optimized coating still maintained strong hydrophilicity and anti-oil-fouling performance, highlighting its promise for practical applications. Download: Download high-res image (267KB) Download: Download full-size image
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Advanced Science
·
2024
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IF 14.3
Jiahui Hou,Yanpeng Lin,Chencheng Zhu,Yupeng Chen,Rongmin Lin,Hancheng Lin,Dahai Liu,Daogang Guan,Bin Yu,Jun Wang,Hangtian Wu,Zhuang Cui
Chondrocyte senescence and reduced lubrication play pivotal roles in the pathogenesis of age-related osteoarthritis (OA). In the present study, highly lubricated and drug-loaded hydrogel microspheres are designed and fabricated through the radical polymerization of sulfobetaine (SB)-modified hyaluronic acid methacrylate using microfluidic technology. The copolymer contains a large number of SB and carboxyl groups that can provide a high degree of lubrication through hydration and form electrostatic loading interactions with metformin (Met@SBHA), producing a high drug load for anti-chondrocyte senescence. Mechanical, tribological, and drug release analyses demonstrated enhanced lubricative properties and prolonged drug dissemination of the Met@SBHA microspheres. RNA sequencing (RNA-seq) analysis, network pharmacology, and in vitro assays revealed the extraordinary capacity of Met@SBHA to combat chondrocyte senescence. Additionally, inducible nitric oxide synthase (iNOS) has been identified as a promising protein modulated by Met in senescent chondrocytes, thereby exerting a significant influence on the iNOS/ONOO-/P53 pathway. Notably, the intra-articular administration of Met@SBHA in aged mice ameliorated cartilage senescence and OA pathogenesis. Based on the findings of this study, Met@SBHA emerges as an innovative and promising strategy in tackling age-related OA serving the dual function of enhancing joint lubrication and mitigating cartilage senescence.
研究领域:
生物医学工程
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药学
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风湿病学
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老年学
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分子生物学
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Nano Energy
·
2025
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IF 17.1
Xiaoshuang Wang,Meixiu Song,Hongbo Liang,Jingzhe Hong,Baonian Zhu,Yanan Liu,Dechang Jia,Xiaoxiao Huang,Yu Zhou
Aqueous zinc metal batteries are promising for grid energy storage; however, their application is hindered by the irreversibility of Zn chemistry. Electrolyte additives have been demonstrated to be effective in improving Coulombic efficiency (CE), yet the incomplete understanding of the interplay between additives and Zn metal anode (ZMA) is an obstacle to advancing electrolytes. Herein, we propose and validate a molecular design strategy based on two critical factors, dipole moment and isotropic polarizability, which characterize the dynamic nature of additive molecules at the charged interface between ZMA and electrolyte. This design guideline inspires an exemplar molecule, choline glycerophosphate (GPC), to be used as an additive in aqueous ZnCl 2 electrolyte. The ZnCl 2 +GPC electrolyte achieves a high CE of 99.9 % for Zn plating/stripping. The comprehensive analysis of ZMA/electrolyte interface reveals a dynamic interplay mode that is responsible for the excellent reversibility. The high dipole moment and isotropic polarizability of GPC enable it to adsorb on ZMA surface during both charge and discharge processes, while the water reduction is greatly inhibited. The application of ZnCl 2 +GPC electrolyte is demonstrated in Zn||NH 4 V 4 O 10 cells at room and sub-zero temperatures. This molecular engineering strategy facilitates the rational design of electrolytes and can be extended to other aggressive alkali-metal batteries.
研究领域:
电化学
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能源材料
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界面化学
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分子工程
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储能技术
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LANGMUIR
·
2022
·
IF 4.331
Hui Zhang,Yi Li,Junping Miao,Xinran Zhu,Jing Yang,Qinglei Zhang,Yanfu Yang,Junqiang Zhao,Yunxia Hu,Yiping Zhao,Li Chen
N-Oxide zwitterionic polyethyleneimine (ZPEI), a new kind of aqueous phase monomer synthesized by commercially branched polyethyleneimine (PEI) via oxidation reaction, was prepared for fabrication of thin-film composite (TFC) polyamide membranes via interfacial polymerization. The main factors, including the monomer concentration and immersion time of the aqueous phase and organic phase, were investigated. Compared with PEI-TFC membranes, the obtained optimal defect-free ZPEI-TFC membranes exhibited a lower roughness (3.3 ± 0.3 nm), a better surface hydrophilicity, and a smaller pore size (238 Da of MWCO). The positively charged ZPEI-TFC membranes (isoelectric point at pH 8.05) showed higher rejections toward both divalent cationic (MgCl2, 93.0%) and anionic (Na2SO4, 96.1%) salts with a water permeation flux of up to 81.0 L·m–2·h–1 at 6 bar, which surpassed currently reported membranes. More importantly, mainly owing to N-oxide zwitterion with strong hydration capability, ZPEI-TFC membranes displayed a high flux recovery ratio (97.0%) toward a model protein contaminant (bovine serum albumin), indicating good anti-fouling properties. Therefore, the novel N-oxide zwitterion functionalized positively charged nanofiltration membranes provide an alternative for water desalination and sewage reclamation.
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NEW JOURNAL OF CHEMISTRY
·
2020
·Vol. 44
·期 5
·2059-2069
·
IF 3.288
Ding Sun,Peiyun Li,Xiong Li,Xuefen Wang
Here, a nanocomposite functional coating consisting of poly(sulfobetaine methacrylate)–vinyltrimethoxysilane–silica (PSBMA@VTMO@silica) hybrid nanoparticles and a combined adhesive of tannic acid (TA) and polyethylene glycol (PEG) was successfully developed through a facile deposition method, and is able to effectively block the adhesion of proteins and subsequent biofouling deposition. The PSBMA@VTMO@silica hybrid nanoparticles could endow the functional coating with high roughness, hydrophilicity and excellent abrasion-resistant properties, and the TA–PEG composite adhesive could be used as a bridge connecting the hybrid nanoparticles and the substrate to ensure the robustness and durability of the coating. Benefiting from these, the as-obtained coating not only is highly resistant to the fouling organisms but also exhibits high stability in harsh environments (for example, it maintained stable hydrophilicity for longer than 40 days in artificial seawater and still possessed good anti-adhesion of proteins after 12 sandpaper abrasion cycles). Additionally, the versatility of this approach was confirmed by successful application to other materials, such as nylon boards, polyethylene sheets and stainless steel foils. Overall, this work enriches the exploration of feasible, stable, and effective marine antifouling coatings under environmentally friendly conditions.
研究领域:
材料科学
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海洋科学
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化学工程
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表面化学
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高影响因子
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