CRYSTENGCOMM
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2022
·Vol. 24
·期 47
·8321-8325
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IF 3.756
Shang-Wei Yuan,Pei-Hui Shan,Mao-Xiao Yang,Pei-Hua Ma,Timothy J. Prior,Carl Redshaw,Gang Wei,Zhu Tao,Xin Xiao
Herein, we have investigated the host–guest inclusion complexes formed on interaction of the symmetric tetramethyl-substituted cucurbit[6]uril (TMeQ[6]) with glycine (Gly) under different conditions. The interactions have been studied both in solution (by 1H NMR spectroscopy and mass spectrometry) and in the solid state by single crystal X-ray diffraction. The molecular structures of two products are reported, namely TMeQ[6]·(H2O)2(PO4)(NH3CH2COOH)2 (1) and TMeQ[6]·Ca(H2O)5·(Cl)3(NH3CH2COOH)·16H2O (2). Complex 1 adopts a hydrogen-bonded dimeric structure with two glycinium ions contained within a TMeQ[6] molecule with the NH3+ portions of the two molecules located just above the opposite rims of the bowl and forming hydrogen bonds with C–O. In 2, there are centrosymmetric dimers bridged by pairs of calcium ions.
研究领域:
化学
·
材料科学
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DOI
高影响因子
Materials Chemistry Frontiers
·
2022
·Vol. 6
·期 19
·2859-2868
·
IF 8.683
Ming Liu,Ran Cen,Ji-Hong Lu,Tie-Hong Meng,Chun-Rong Li,Carl Redshaw,Timothy J. Prior,Zhu Tao,Xin Xiao
Fluorescent nitrogen and fluorine doped carbon dots (CDs) were prepared by a hydrothermal method using levofloxacin (LVFX) and cucurbit[6]uril (Q[6]) as the nitrogen and carbon sources, respectively. Decomposition of LVFX occurred at elevated temperature affording N,N′-desethylene levofloxacin hydrochloride (N,N′-DLH). The crystal structure of the resulting inclusion complex N,N′-DLH@Q[6]·[CdCl4]2(H3O)·9H2O was determined, where N,N′-DLH is protonated on each of the terminal nitrogens and the quinone functionality is a quinol which forms an intramolecular hydrogen bond to the carboxylic acid. The synthesized N,N′-DLH containing Q[6]-CDs emitted intense blue fluorescence with high photostability and exhibited stability at high ionic strength. In particular, the original rigid macrocyclic skeletons of these hosts were retained during the fabrication process, which helps in uniquely distinguishing them from other reported CDs. Meanwhile, the performance of the Q[6]-CDs was characterized using fluorescence and NMR spectroscopies. Subsequently, using the obtained Q[6]-CDs, an efficient sensing method for L-tryptophan (L-Trp) and capecitabine (CAP) has been developed based on macrocyclic host–guest chemistry. Under applicable conditions, the detection limits for L-Trp and CAP were calculated to be 5.13 × 10−8 M and 1.48 × 10−8 M, respectively.
研究领域:
分析化学
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材料科学
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药物化学
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DOI
高影响因子
NEW JOURNAL OF CHEMISTRY
·
2022
·Vol. 46
·期 11
·5026-5033
·
IF 3.925
Yuhua Luo,Wei Xiang,Xinyu Zhang,Liqiao Hu,Yongping Dong
In this work, an electrogenerated chemiluminescence (ECL) sensor was fabricated to detect silver ions based on the competitive interaction between luminol, silver ions and cucurbit[6]uril (Q[6]). The Q[6]-modified electrode (Q[6]/GCE) exhibited the best electrochemical response among various Q[n]-modified electrodes and was selected for ECL measurements. Strong anodic luminol ECL was obtained at the Q[6]/GCE due to the interaction between luminol, oxygen, and Q[6]. In the presence of Ag+, the strong coordination interaction between Ag+ and Q[6] could decrease the concentration of luminol and oxygen on the electrode surface, resulting in a decreased ECL signal. The variation of the ECL intensity was linearly correlated with the Ag+ concentration. Therefore, an ECL sensor for the quantitative detection of Ag+ was proposed. Under the optimal conditions, Ag+ can be detected in the range of 10 nM to 5 μM, and the detection limit was calculated as 8.2 nM (3σ). The proposed ECL sensor shows outstanding specificity and accuracy, indicating that cucurbit[n]urils have great potential applications in the detection of metal ions.
研究领域:
分析化学
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材料科学
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环境科学
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产品关联
DOI
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2024
·
IF 13.3
Pengfei Yang,Yanan Liu,Gowan-Hugh Whalley,Chengzhi Guo,Ya Li,A.Ozgur Yazaydin,Zhongyi Jiang,Marc-Olivier Coppens,Yang Lan
Graphene oxide (GO) membranes exhibit promising potential in nanofiltration due to their controllable transport channel size and low transport resistance of water molecules, resulting in exceptional water permeability. However, the trade-off between water flux and rejection ratio stemming from tightly packed interlayers poses a challenge to the application of GO membranes in nanofiltration. To overcome this trade-off, a practical method is urgently needed to regulate the interlayer space of GO membranes. In this study, a macrocyclic molecule with a rigid porous structure, cucurbit[6]uril (CB[6]), has been introduced to enlarge and precisely adjust the interlayer distance of GO membranes, effectively addressing the trade-off dilemma. The interlayer distance can be precisely adjusted within a range of 0.46 to 1.35 nm, making it suitable for the removal of small organic molecules from wastewater. Through the optimization of GO and CB[6] quantities, the GO membrane containing 20 µg GO and 49.9 wt% CB[6] (CB6GO-4) demonstrates a high pure water flux (PWF) exceeding 171.3 L m -2 h −1 bar −1 , more than 5.9 times higher than a pure GO membrane (28.8 L m -2 h −1 bar −1 ), alongside a dye rejection ratio over 92 %, indicating the promising potential of CB[6]-intercalated GO membranes in removing organics from industrial saline wastewater.
研究领域:
材料科学
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环境工程
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产品关联
DOI
高影响因子
JOURNAL OF MEMBRANE SCIENCE
·
2020
·
IF 7.183
Jing Cai,Xue-Li Cao,Yi Zhao,Fu-Yi Zhou,Zhaoliang Cui,Yong Wang,Shi-Peng Sun
In this work, annular supramolecular cucurbit[6]uril (CB6) and dendritic polyamidoamine (PAMAM) were employed to construct high-performance nanofiltration (NF) membranes via one-step interfacial polymerization (IP) process. The obtained membrane features not only the enlarged polyamide tunnels based on the large steric hindrance of CB6 and PAMAM but also the novel hydrophobic rotaxane tunnels based on the host-guest chemistry between CB6 and piperazine (PIP) or PAMAM. The CB6/PAMAM-modified membrane achieved nearly four times enhancement of pure water permeability (PWP) compared to the unmodified traditional membranes with still high Na 2 SO 4 rejection. This indicates the positive contribution of CB6/PAMAM-modification to overcome the “trade-off” effect limiting NF development. In addition, the modified membrane shows the industry-leading separation performance for monovalent and bivalent anions due to the cooperation between the modified pore-size and surface charge. More valuably, CB6/PAMAM-modified membrane manifests the strong anti-fouling property not only in inorganic salt system but also in organic pollutant system based on the modified surface characteristics, indicating its broader application fields. This provides a feasible method to prepare a high-performance anti-fouling NF membrane.
研究领域:
材料科学
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环境工程
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化学工程
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产品关联
DOI
高影响因子
CHEMISTRY-A EUROPEAN JOURNAL
·
2017
·Vol. 24
·期 9
·2242-2248
·
IF 5.317
Dandan Jiang,Xiqian Li,Qiong Jia
Graphical A facile synthetic strategy based on host–guest interactions was developed to prepare multilayer cucurbit[6]uril-based magnetic nanoparticles, MNPs-(HA-DAH 5 /HA-CB[6] 5 ). The compound was employed as a blood purification material for the removal of LDL from plasma because it had good blood compatibilitiy and could be easily separated with an external magnet. Efficient removal of low density lipoprotein (LDL) is a key challenge due to its high level in plasma as a primary risk factor in the pathogenesis of atherosclerotic cardiovascular disease. In this work, a facile synthesis strategy based on host–guest interactions was developed to prepare multilayer cucurbit[6]uril-based magnetic nanoparticles, MNPs-(HA-DAH 5 /HA-CB[6] 5 ). The compound was employed as a blood purification material for the removal of LDL from plasma because it had good blood compatibility and could be easily separated with an external magnet. The efficient removal of LDL was attributed to the electrostatic interactions between the positive charged apoB-100 domain of LDL and the negative charged adsorbent. Moreover, the prepared material exhibited high recyclability and could release LDL in physiological saline for recyclable use. MNPs-(HA-DAH 5 /HA-CB[6] 5 ) offered promising perspectives and broad applications in extracorporeal treatment for the removal of LDL.
研究领域:
生物医学工程
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材料科学
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心血管疾病研究
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产品关联
DOI
PubMed
高影响因子
JOURNAL OF MOLECULAR STRUCTURE
·
2024
·
IF 4
Qiqi Wang,Mei Liu,Shuo Wang,Lulu Shi
A novel supramolecular framework [Cd(QDS) 2 ]·(CB[6]) 2 ( 1 ) based on cucurbit[6]uril (CB[6]) and 8-hydroxyquinoline-5-sulfonic acid ion (QDS − ) was successfully synthesized under solvothermal conditions. The single crystal X-ray diffraction analyses indicated that the construction of this supramolecular framework is attributed to the non-covalent interactions between the QDS − and the outer surface of CB[6]. The performance study demonstrates that 1 exhibits a remarkable sensitivity and selectivity in detecting anions Cr 2 O 7 2− , MnO 4 − , furan antibiotics nitrofurantoin (NFT) and nitrofurazone (NFZ) through fluorescence quenching with the limit of detection (LOD) were 95, 89, 132, and 113 ppb, respectively. Meanwhile, due to the remarkable fluorescent properties of 1 , anti-counterfeiting marks were incorporated into the positioning boxes of quick response (QR) codes. The anticounterfeiting signs appear yellow in daylight while exhibit bright green fluorescence when excited at 365 nm. Furthermore, 1 also have been successfully applied to real samples with satisfactory results. These remarkable findings suggest that 1 hold promise as an effective fluorescent sensor.
研究领域:
化学
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材料科学
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环境科学
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DOI
高影响因子
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
·
2015
·Vol. 2015
·期 31
·6806-6810
·
IF 3.065
Li Liu,Yuhang Yao,Xuefang Zhang,Ce Hao
Graphical A highly ordered 3D framework from 1,5-naphthalenedisulfonate (1,5-NDS) and cucurbit[6]uril (CB[6]) is synthesized, wherein the 1,5-NDS anions act as linkers to connect the CB[6] units together through C–H ··· O H-bonds. The fluorescence wavelength of the assembly structure is blueshifted relative to that of 1,5-NDS and the fluorescence intensity is decreased, which are ascribed to the formed H-bonds. A highly ordered 3D framework from 1,5-naphthalenedisulfonate (1,5-NDS) and cucurbit[6]uril was synthesized and structurally determined by single-crystal X-ray diffraction analysis. The crystal structure demonstrates that the 1,5-NDS anions act as linkers to connect the cucurbit[6]uril units together through C–H ··· O hydrogen bonds between the 1,5-NDS anions and cucurbit[6]uril. Furthermore, with 1,5-NDS as the fluorophore, the fluorescence properties of the corresponding assembly structure were investigated in the solid state. Relative to that observed for 1,5-NDS, the assembly exhibited a blueshift in the fluorescence wavelength from λ = 406 to 340 nm along with decreased fluorescence intensity. Theoretical calculations were in good agreement with the experimental results and disclosed that the fluorescence mechanism of the assembly structure could be ascribed to the hydrogen bonds formed between the 1,5-NDS anion and cucurbit[6]uril.
研究领域:
化学
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材料科学
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产品关联
DOI
高影响因子
AICHE JOURNAL
·
2019
·Vol. 66
·期 4
·e16879
·
IF 3.463
Xue-Li Cao,Jia-Lin Guo,Jing Cai,Mei-Ling Liu,Susilo Japip,Weihong Xing,Shi-Peng Sun
The considerable performance enhancement of small molecule-sieving nanofiltration membrane has been achieved by the functional combination between host–guest chemistry and interfacial polymerization (IP) for the first time in this work. First, the water-insolubility of cucurbit[6]uril (CB6) was ameliorated by constructing host–guest complex (CB6-PIP) with piperazine. Second, the incorporation of water-soluble CB6-PIP in the selective layer via IP leads to the generation of not only the enlarged conventional polyamide network tunnels but also rotaxane tunnels. Such enrichment of solvent transport tunnels contributes to an amazing pure water permeability of 15.5–25.4 Lm −2 bar −1 h −1 , three times higher than that of traditional polyamide membranes, with a high R/MgSO 4 of 99.5–92.5%, perfect SO 4 2− /Cl − selectivity due to the electronegative contribution of CB6, as well as untapped potential in organic solvent nanofiltration. This work not only provides a fire-new strategy to design new type of NF materials but also promotes the application of CBs in many other fields.
研究领域:
材料科学
·
化学工程
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产品关联
DOI
高影响因子
ChemSusChem
·
2021
·Vol. 14
·期 8
·1847-1852
·
IF 8.928
Ya Zhang,Xiao-Yu Zhang,Kai Chen,Wei-Yin Sun
Graphical There by the grace of gourd : Cu 2 O modified by cucurbit[6]urils acts as an efficient supramolecular inorganic catalyst for the electrochemical CO 2 reduction reaction. In 0.5 m KHCO 3 , it demonstrates a maximum total faradaic efficiency (FE CO+formate ) of 93.96 % at −0.7 V vs. RHE Electrochemical conversion of CO 2 into value-added fuels and feedstocks attracts worldwide attention to mitigate energy and environmental problems. However, pursuing highly efficient electrocatalyst is still a challenge. In this study, cuprous oxide (Cu 2 O) modified by cucurbit[6]urils (Q[6]), a kind of rigid macromolecule, is found to act as an efficient supramolecular inorganic nanocomposite catalyst for the electrochemical CO 2 reduction reaction (CO 2 RR) to C 1 fuels. This catalyst affords a high total faradaic efficiency (FE CO+formate ) of 93.96 % at a potential of −0.7 V vs. reversible hydrogen electrode and over 85 % from −0.6 to −0.9 V in 0.5 M KHCO 3 , which is higher than that of pure Cu 2 O (39.89 %). The enhancements in selectivity and activity for CO 2 RR could significantly benefit from the strong CO 2 adsorption capacity and hydrophobic nature of the cavity of Q[6], which simultaneously trap gaseous reactants near the catalyst to tune the local environment and limit the diffusion of water molecules. This study provides a strategy to adjust catalytic environments through supramolecular engineering.
研究领域:
材料科学
·
环境科学
·
化学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
CHEMICAL PHYSICS LETTERS
·
2021
·
IF 2.328
Chenrui Jiang,Zhaorui Song,Meriem Fizir,Ping Yang,Meiru Liu,Pierre Dramou,Hua He
The interaction between cucurbit[6]uril and chain amino acids was studied via fluorescence probe method, molecular simulation, Fourier transform infrared spectroscopy, and nuclear magnetic resonance spectroscopy. The experimental results of this work show that the cucurbit[6]uril host possesses a strong binding force with the chain amino acids leucine and methionine, and can form a host–guest inclusion complex. At the same time, the side chain alkyl moieties of the guests leucine, methionine and valine are contained in the hydrophobic cavity of cucurbit[6]uril, but the host–guest interaction between cucurbit[6]uril and valine molecule is weak.
研究领域:
化学
·
生物化学
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DOI
高影响因子
INORGANICA CHIMICA ACTA
·
2023
·
IF 2.8
Zhi-Nian Liu,Jian-Hang Hu,Yu Xiong,Jia-Yi Zhang,Run-Xin Hou,Chun-Rong Li,Tie-Hong Meng,Timothy J. Prior,Carl Redshaw,Xin Xiao
In this study, single crystal X-ray diffraction and 1 H NMR spectroscopy were used to examine the interaction of the guest 1,5-pentanediamine with inverted cucurbit[6]uril ( i Q[6]) in the presence of [ZnCl 4 ] 2− anion. The results show that [ZnCl 4 ] 2− and [Zn(H 2 O)Cl 3 ] − anions form a honeycomb framework structure, and i Q[6] forms a 1:1 complex with 1,5-pentanediamine. Inverted cucurbit[6]uril forms molecular chains via outer surface interactions, which in turn fill in the honeycomb framework structure. The amino groups at both ends of the 1,5-pentanediamine guest are situated at the entrance of the central cavity, while the alkyl chain part resides in the central cavity of the i Q[6].
研究领域:
化学
·
材料科学
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产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）