Rong Zhao,Wei Jia,Youfa Jiang,Xiaoju Wu,Xuefeng Jiang,Saijie Song,Jun Zhang,He Shen,Jian Shen
Lambda-Cyhalothrin (LC) is a high-efficiency and broad-spectrum insecticide. However, due to its poor water dispersion stability and unstable efficacy, it has many problems in practical applications. Therefore, there is an urgent need to develop new formulations with stability, low toxicity, and environmental friendliness to overcome the drawbacks of traditional pesticide formulations. This study designed an iron-based metal–organic framework (MIL-101(Fe)) as a nanocarrier for the loading of LC and then surface modified it with polydopamine (PDA) to form the nanopesticide PDA-LC-MIL. The results showed that PDA-LC-MIL has good stability and can achieve controlled release of pesticide by adjusting the pH value. In addition, it also has a good leaf affinity and can effectively adhere on crop leaves, improving the utilization rate of pesticides. The insecticidal experimental results indicate that PDA-LC-MIL has significantly improved sustained insecticidal activity. PDA-LC-MIL also has good biocompatibility and shows no significant inhibitory effect on seed germination and seedling growth of Vigna radiata (L.) Wilczek and maize. Therefore, we firmly believe that MIL-based nanopesticides will have broad application prospects in the field of green pesticides and modern agriculture.
In recent years, stimuli-responsive controlled-release pesticide formulations have drawn extensive as they show huge potential in the practical application of agriculture. Herein, a multifunctional composite nanocarrier was prepared by our group, Poly(N-isopropylacrylamide) modified graphene oxide (PNIPAm-GO), this is a temperature-responsive release pesticide formulation that can regulate pesticide release based on the temperature change. Lambda-cyhalothrin (LC) was loaded on PNIPAm-GO nanocomposite carrier via a simple physisorption process and LC@PNIPAm-GO exhibited temperature-responsive controlled release performance leading to release of LC at a specified temperature and extended its persisted release time. In addition, the LC@PNIPAm-GO controlled-release pesticide formulations showed both good water solubility and dispersion stability while its anti-UV property. Furthermore, we also assessed the biological safety of LC@PNIPAm-GO and proved that PNIPAm-GO is non-toxic. The study of this temperature-responsive pesticide formulation has promoted the development of intelligent pesticide formulations to great extent.
危险品化学品经营许可证（带存储）