FOOD CHEMISTRY
·
2025
·
IF 9.8
Huiling Li,Li Tian,Shuning Yang,Chao Li,Ruidan Li,Yujia Song,Yanjia Guo,Xuwen Li
To sensitively monitor trace-level of malathion (MAT) in vegetable samples, an ultrasensitive solid-state electrochemiluminescence (ECL) sensor was proposed based on TiO 2 @CdSe and Ru(bpy) 3 2+ @Ag NPs. In this system, the introduction of Ag NPs enhanced the initial ECL signal of Ru(bpy) 3 2+ - tripropylamine (TPrA). When TiO 2 @CdSe was introduced into the system, the ECL signal was further enhanced, which may be due to the synergistic effect of the two complexes. Based on the fact that the addition of MAT causes ECL strength to decrease, a ECL sensor for the ultrasensitive trace detection of MAT has been successfully established. Under the optimized conditions, a wide liner detection range of MAT concentrations from 4.0 × 10 −14 to 4.0 × 10 −9 mol L −1 and a low detection limit (S/N = 3) of 1.3 × 10 −14 mol L −1 were obtained. The ECL sensor has been applied to the detection of vegetable samples and satisfactory results were obtained.
研究领域:
分析化学
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环境科学
·
食品安全
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产品关联
DOI
PubMed
高影响因子
MICROCHEMICAL JOURNAL
·
2022
·
IF 5.304
Juan Lu,Xiangyu Shan,Qian Wu,Yingjie Zhao,Chao Li,Huiling Li,Shuning Yang,Li Tian
Metal oxides containing iron and zinc (ZnO-Fe 2 O 3 ) combined with ruthenium bipyridine [Ru(bpy) 3 2+ ], graphene oxide (GO) and multi-walled carbon nanotube (MWNTs) were applied in the field of electrochemiluminescence (ECL). And a new solid-state ECL sensor for malathion determination by modifying ZnO-Fe 2 O 3 , Ru(bpy) 3 2+ , GO@MWNTs, Acetylcholinesterase (AchE) and Nafion on the electrode surface. The synthesized ZnO-Fe 2 O 3 and GO@MWNTs with large specific surface area were used as carrier to anchor Ru(bpy) 3 2+ and AchE, respectively. ZnO-Fe 2 O 3 and GO@MWNTs can also be used as accelerators to promote electron transfer of the system. ZnO-Fe 2 O 3 was also involved in the luminescence reaction, which increased the sensitivity of the system together with Ru(bpy) 3 2+ . Taking advantages of the electrocatalysis and electron transport capacity of ZnO-Fe 2 O 3 and GO@MWNTs, the sensor obtained stable and amazing ECL response. The ECL response value decreased after malathion was introduced. In the range of 6.6 × 10 −11 to 6.6 × 10 −7 M, the decrease value (ΔI) was linearly related to the logarithm of malathion concentration, and the detection limit was 2.2 × 10 −11 M. The method was simple and stable, and can be used to determine malathion in vegetable samples.
研究领域:
分析化学
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环境科学
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生物传感技术
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产品关联
DOI
高影响因子
ANALYTICAL LETTERS
·
2020
·
IF 1.467
Xiaoxia Lai,Sizhe Zhang,Guorong Du,Yuxian Wang,Yang Han,Nengsheng Ye,Yuhong Xiang
Malathion is a toxic organophosphorus pesticide. When ingested by humans, it affects the nervous system and endangers health. Herein, a new type of aptamer-based sensor was developed for its determination. The results demonstrate that this sensor has high sensitivity and good selectivity and was successfully used for the determination of malathion in apples. The detection mechanism is as follows. The aptamer is adsorbed on the surface of gold nanoparticles (AuNPs) to prevent the aggregation of AuNPs in a high salt solution. After adding malathion, the aptamer specifically binds to malathion and is removed from the surface of the AuNPs. The quantity of aptamer adsorbed on the surface of AuNPs had a negative relationship with the malathion concentration. The unmodified AuNPs aggregated to different degrees in NaCl solution. In the Fehling reaction, various degrees of aggregated AuNPs catalyze the reduction to different size Cu2O and exhibit different resonance scattering intensities. An excellent linear response between the resonance scattering spectra intensity and malathion concentration was obtained. The limit of detection of the developed method was 5.24 ng/L (15.86 pM). The recovery and repeatability for the apple samples were satisfactory.
研究领域:
分析化学
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环境科学
·
食品安全
✓ 已验证
产品关联
DOI
高影响因子
ANALYTICAL CHEMISTRY
·
2025
·
IF 6.7
Chongyang Mu,Dawei Feng,Mashooq Khan,Haoyang Song,Sundas Munir,Qiongzheng Hu,Li Yu
Cholesteric liquid crystal elastomers (CLCEs) possess a unique characteristic that allows the manipulation of the reflected color by adjusting the spacing between layers. This attribute can create a reliable and cost-effective colorimetric sensing platform for the on-site detection of various substances. In this study, CLCE films were coupled with cross-linked poly(acrylic acid) (CLCE-PAA) or poly(dimethylaminoethyl methacrylate) (CLCE-PDA) films to monitor cholesterol and malathion levels, respectively. In both cases, the color change is recorded by a mobile phone camera, and the reflectance wavelength is measured spectrophotometrically. For on-site detection, a smartphone application was used to capture the film’s image, process the color data into hue (H) values, and calculate the corresponding concentration of the tested analyte via an analysis program. Cholesterol and malathion can be detected within a linear range of 0.2–1.0 mM and 1–10,000 ng/mL, respectively. The corresponding recoveries for actual sample analysis were 86–115% and 87–122% for cholesterol and malathion, respectively. This system offers a practical solution for on-site testing of cholesterol and malathion in biological and environmental samples.
研究领域:
生物传感
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环境监测
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医学检测
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产品关联
DOI
PubMed
高影响因子
JOURNAL OF MATERIALS SCIENCE
·
2023
·Vol. 58
·期 3
·1200-1213
·
IF 4.5
He Chunming,Yan Ru,Xue Qingwang,Li Shuxian,Wang Huaisheng
In this work, polyaniline (PANI) and overoxidized polyaniline (oPANI) nanorods doped by phytic acid (PA) with uniform size of 60–100 nm were prepared and modified on glassy carbon electrode (GCE) as non-enzymatic malathion sensors. Doping of PA has deep influence on structural and morphological properties, conductivity and detection performance of electrode materials. The obtained PANI nanorods doped with PA (PA-PANI) possess high affinity toward malathion, and thus the redox reaction of PANI molecules could be hindered and redox currents were inhibited. The electrode reaction process on PA-PANI/GCE is a typical adsorption-controlled process. By contrast, the oPANI nanorods doped with PA (PA-oPANI) presents good catalytic performance to malathion and the electron transfer process was enhanced and redox currents increased. Correspondingly, the electrochemical reduction process on PA-oPANI/GCE is a typical diffusion-controlled process. Both enzyme-free electrochemical sensors exhibit good stability, anti-interference ability, recovery in real samples and excellent detection performance, with a wide linear range of 0.01–200 ppb and low detection limit (1.58 ppt for PA-PANI and 2.23 ppt for PA-oPANI, respectively), indicating that PA-PANI and PA-oPANI could be used as an excellent malathion sensor. Moreover, the PA-oPANI sensor has some degree of reproducibility through further anodic polarity processing, and the detailed application needs to be further explored.
研究领域:
分析化学
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环境科学
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材料科学
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产品关联
DOI
高影响因子
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
·
2020
·
IF 3.232
Quansheng Chen,Ren Sheng,Pingyue Wang,Qin Ouyang,Ancheng Wang,Shujat Ali,Muhammad Zareef,Md. Mehedi Hassan
Malathion is an organophosphorus pesticide which could remain in agricultural products and exert irreversible harmful effects on human health. Hence, strict monitoring of malathion contents is very significant. Here, a highly sensitive fluorescent aptasensor was developed for the determination of malathion, the system was based on a cationic polymer-mediated fluorescence ‘turn-off’. In this system, malathion-specific aptamers were bound to cationic polymer through electrostatic interactions . To produce fluorescence resonance energy transfer (FRET), negatively charged upconversion fluorescent nanoparticles (UCNPs) and cationic-polymer encapsulated gold nanoparticles (GNPs) were combined. This combination resulted in fluorescence quenching , and the degree of quenching was correlated with the concentration of malathion. Under optimum conditions, the fluorescence intensities were observed to decrease linearly with the rising concentration of the malathion from 0.01 to 1 μM with a detection limit of 1.42 nM. Furthermore, the developed sensor possessed good selective recognition ability for malathion and was successfully used to detect malathion in adulterated tap water and matcha samples with high accuracy.
研究领域:
分析化学
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食品安全
·
生物传感
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DOI
高影响因子
Journal of Analysis and Testing
·
2024
·Vol. 8
·期 2
·170-179
·
IF 5.5
Chen Jia,Long Zerong,Li Yan,Qiu Hongdeng
The establishment of a low-cost and facile approach for the assay of acid phosphatase (ACP) and its inhibitor is a research focus. In this paper, we successfully synthesized NiCo 2 O 4 nanosheets with peroxidase-mimicking activity in alkaline deep eutectic solvents (DESs) composed of NaOH and PEG-200, which can catalyze 3,3′,5,5′-tetramethylbenzidine (TMB) to the oxidation state TMB (ox-TMB) in the presence of H 2 O 2 . Due to L-ascorbic acid-2-phosphate can be hydrolyzed into ascorbic acid by ACP, the peroxidase-like activity of NiCo 2 O 4 nanosheets is inhibited. However, the addition of malathion, an inhibitor of ACP, can inhibit the activity of ACP and thus limit the production of ascorbic acid (AA). Therefore, a colorimetric approach can be established for highly sensitive and selective detection of ACP and malathion with detection limits of 0.032 U/L and 0.65 nmol/L, respectively. More importantly, this method can be successfully applied to malathion detection in environmental samples tap water and food cucumber juice, indicating that it has potential application prospects in environmental and agricultural fields.
研究领域:
分析化学
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环境科学
·
农业科学
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DOI
高影响因子
SENSORS AND ACTUATORS B-CHEMICAL
·
2021
·
IF 7.46
Mengna Huang,Yanping Fan,Xiang Yuan,Lin Wei
Malathion is widely applied in agriculture as one of organophosphorus pesticides (OPs) and easily causes a number of health and environmental problems. Traditional methods for analyzing malathion residues have failed to meet the current requirements of detection. To address this challenge, we designed a colorimetric-based single particle detection (SPD) method to quantify malathion using MnO 2 -coated gold nanoparticles (GNP@MnO 2 NPs) as the probe. In the existence of alkaline phosphatase (ALP), p-aminophenyl phosphate (p-APP) can be hydrolyzed to p-aminophenol (p-AP), which employs as a reductant to induce MnO 2 to Mn 2+ and make the gold core exposure. With the dark field optical microscopy (DFM), the color change of the probe can be readily observed at the single particle level. However, malathion is able to inhibit the activity of ALP and makes the color of the probe remain. Thus, the content of malathion can be accurately quantified by monitoring the changes in color and scattering intensity of the probe. The linear range of this assay is 0.001–0.1 ng/mL and the limit of detection (LOD) is as low as 0.82 pg/mL. In addition, degradation of malathion can be achieved due to the interaction between malathion and ALP. Therefore, this strategy offers new insights on the design of an ultrasensitive assay for OPs detection and degradation in the future.
研究领域:
环境科学
·
分析化学
·
生物医学工程
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产品关联
DOI
高影响因子
MICROCHEMICAL JOURNAL
·
2023
·
IF 4.8
Xin Zhang,Li Tian,Zhuo Sun,Qian Wu,Xiangyu Shan,Shuning Yang,Huiling Li,Chao Li,Ruizhan Chen,Juan Lu
A novel electrochemiluminescence (ECL) biosensor for ultrasensitive detection of malathion was constructed by multiple signal amplification strategy. In this protocol, Ru(bpy) 3 2+ (as luminophore) was firstly immobilized on hydroxyapatite (HAP) to produce a stable composite film on the electrode surface. ECL signal is amplified by the adsorption of more Ru(bpy) 3 2+ onto HAP with high loading capacity. After Au@ZIF-7 nanocomposite (as co-reaction promoter) was modified to the electrode surface, the ECL signal was further increased. In addition, in order to enhance the selectivity of the sensor, the porosity of Au@ZIF-7 was used to load acetylcholinesterase (AChE). The ECL signal was significantly enhanced in the solution containing acetylthiocholine, possibly due to the promoting effect of the reaction products thiocholine of AChE and acetylthiocholine (ATCl). When the biosensor was incubated with malathion, ECL signal decreased gradually. Under optimal conditions, the linear range of malathion was wide in the range of 3.72 × 10 −11 to 3.72 × 10 −6 mol/L and the LOD of 1.32 × 10 -11 mol/L. The method has the advantages of outstanding stability and good specificity. It had a potential application prospect in the detection of OPs.
研究领域:
分析化学
·
环境科学
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产品关联
DOI
高影响因子
ACS Applied Nano Materials
·
2024
·
IF 5.3
Xuemei Pi,Yuanyuan Wang,Xianwen Kan
The intensive application of organophosphorus pesticides (OPs) and their acute toxicity have raised significant threats to human health. Herein, an electrochemiluminescence (ECL) nanomaterial was synthesized by successive modification of the Zn–N structure and Prussian blue (PB) nanoparticles on cerium(III) tetrakis(4-carboxyphenyl)porphine (CeTCPP). Because of the combination of CeTCPP (luminophore) and the Zn–N structure (coreaction accelerator) in one nanostructure, Zn-CeTCPP exhibited a high ECL response based on the self-enhancement strategy. The ECL signal was remarkably quenched in turn due to the resonance energy transfer (RET) from Zn-CeTCPP to PB. However, PB was disassembled in the presence of acetylcholinesterase and acetylthiocholine since the produced acetic acid and thiocholine destroyed PB and reduced PB to Prussian white, respectively. Therefore, the recovered ECL signal was employed to sensitively detect malathion with a wide linear range of 1.0 × 10–13–1.0 × 10–7 g/mL and a low limit of detection of 13 fg/mL, endowing the present ECL-RET sensor with excellent prospects for practical application based on the self-enhancement and acceptor disassembly strategies.
研究领域:
分析化学
·
环境科学
·
生物传感
✓ 已验证
产品关联
DOI
高影响因子
MICROCHEMICAL JOURNAL
·
2023
·
IF 4.8
Congyi Zhao,Yaxu Zhao,Wei Guo,Xiong Lu,Faming Gao
Multifunctional nanocomposites derived from metallic-organic frameworks @ metallic-organic frameworks (MOFs@MOFs) based on nanoarchitectonics may provide an innovative approach for the design of promising biosensors. A novel electrochemical biosensor based on tribulus-shaped ZrO 2 @Fe 2 O 3 -C nanocomposites for ultra-sensitive determination of organophosphorus pesticides (OPs) was prepared the pyrolysis of UiO-66@MIL-88B. ZrO 2 from the inner UiO-66 displayed an ultrahigh adsorption capability for OPs, and the interface electronic interaction of ZrO 2 @Fe 2 O 3 made Fe 2 O 3 positive, which can fix and enrich acetylcholinesterase (AChE) in the outer layer, since AChE was a negatively-charged enzyme. The dual enrichment property and synergistic effect of ZrO 2 @Fe 2 O 3 -C were responsible for enhanced detection performances toward OPs, including a wide linear range (3.07 × 10 −14 M−3.07 × 10 −8 M) and a low limit of detection (3.9 × 10 −15 M) (S/N = 3). The emergence of the multifunctional nanocomposites, through calcining MOFs@MOFs, opens a new chapter for the construction of biosensors for OPs determination.
研究领域:
分析化学
·
环境监测
·
纳米材料
·
生物传感器
·
电化学
✓ 已验证
DOI
高影响因子
JOURNAL OF ELECTROANALYTICAL CHEMISTRY
·
2018
·
IF 3.235
Yu Xie,Yunhui Yu,Limin Lu,Xue Ma,Lei Gong,Xigen Huang,Guangbin Liu,Yongfang Yu
In this work, a copper oxide nanoparticles (CuO-NPs) electro-catalyst was prepared on three-dimensional graphene (3DGR) and used as non-enzymatic sensing platform for malathion detection. The structural and morphological properties of the CuO-NPs/3DGR nanocomposite were characterized by scanning electron microscopy (SEM), X-ray photoelectron spectroscopy (XPS) and X-ray diffraction (XRD). 3DGR framework with pleated structures provided a large surface area for high dispersion of the CuO-NPs. The obtained CuO-NPs/3DGR nanocomposite was noted to possess high affinity towards malathion, and thus the redox reaction of CuO could be hindered. This feature was utilized to design as a simple strategy for electrochemical detection of malathion. The experimental parameters including accumulation time, pH value of buffer solution, and the volume of modified composite were optimized. Under optimal conditions, the CuO-NPs/3DGR modified electrode could detect malathion down to 0.01 nM on the basis of the suppressed signal measurements. The high sensitivity can be ascribed to the fact that the 3DGR worked as high-surface-area substrate to anchor CuO-NPs and provided excellent conductive pathways to promote electron transfer. Furthermore, for the determination of malathion in real samples, the sensor showed good recovery, stability, and selectivity.
研究领域:
分析化学
·
环境科学
·
材料科学
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）