NEW JOURNAL OF CHEMISTRY
·
2017
·Vol. 41
·期 4
·1834-1839
·
IF 3.269
Ying Zhang,Zijian Gao,Zhe Yu,Xiuyan Ren,Lijie Duan,Guang Hui Gao
In this manuscript, hydrogels with pH-tunable mechanical properties were prepared via transforming the non C–C covalent synergistic interactions of hydrogen bonding, metal ion coordination and hydrophobic effects. The fracture stress of hydrogels exhibited a tendency to firstly decrease and then increase with an increase of pH from 3.0 to 9.0. That is, the fracture stress was enhanced due to the synergistic interactions of hydrophobic effects and hydrogen bonding among carboxylic acid groups at pH 3.0. Then, the strength gradually decreased due to the disappearance of hydrogen bonding at pH from 3.0 to 5.0. Moreover, the fracture stress was also significantly enhanced at pH over 5.0 due to the synergistic interactions of hydrophobic effects and metal ion coordination. Consequently, it is envisioned that the strategy to design novel hydrogels with pH-tunable mechanical properties would provide more interesting directions for hydrogels based on non C–C covalent synergistic interactions in potential biomedical applications.
研究领域:
材料科学
·
生物医学工程
✓ 已验证
产品关联
DOI
高影响因子
ACS Applied Materials & Interfaces
·
2018
·
IF 8.097
Yuan Zhan,Lifeng Lin,Min Chen,Limin Wu
Dual-state emission (DSE) fluorophores with strong photoluminescence in both solution and solid states have wide applications in fluorescent probes and photoelectric devices. However, most of the existing DSE fluorophores involve complex synthetic strategies or only one or two emission colors in the solid state, which may hinder their practical applications. Herein, we report a facile and effective strategy to fabricate a kind of novel adjustable DSE fluorophore TPAA–Cu based on the small molecule terephthalic acid (TPA) and ascorbic acid (AA) with CuCl2 as the catalyst. Not only can the TPAA–Cu solution emit blue, blue-green, and yellow colors depending upon the pH of solution, but also it shows reversible pH-tunable fluorescence colors. More importantly, corresponding TPAA–Cu solid fluorophores with blue, blue-green, and yellow colors can also be obtained with the quantum yields of 16.3, 26.7, and 29.6%, respectively.
研究领域:
材料科学
·
光学
·
化学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
CHEMISTRY OF MATERIALS
·
2022
·
IF 10.508
Wenchao Xu,Yi Nan,Yijie Jin,Xinran Chen,Manqing Xie,Chongyi Chen,Chuanzhuang Zhao
The adhesion to wet, acidic, and saline biointerfaces with large deformation is important in the fields of wound dressing and motion monitoring but has proven to be extremely challenging. There is a need for a facile method to improve the stretchability and salt resistance simultaneously. Here, an ultrastretchable, pH-tunable, surface-adaptive, and salt-resistant hydrogel adhesive is reported. The hydrogel adhesive is prepared through cross-linking acrylamide with a supramolecular complex of poly(β-cyclodextrin) (PCD) and benzimidazole (BI). The dynamic association between PCD and BI causes an extra energy dissipation and improves the breaking strain to be larger than 4000%. The hydrogel exhibits stable adhesiveness to varieties of surfaces due to the multiple types of hydrogel–surface interactions, including ionic bond, π–π stacking, and hydrogen bond. Notably, the adhesive strength of the hydrogel gets significantly enhanced in an acidic environment and shows no attenuation in a saline environment. This is due to the unique adjacent cation−π structure of BI: the imidazole can be protonized upon acidification, and the phenyl group can repel water and enhance the ionic attraction with the substrates. The ultrastretchability, the stable adhesion on biointerfaces, and the salt resistance render the hydrogel a promising candidate for the surgical patch and motion sensors that serve in wet, acidic, and dynamic environments.
研究领域:
生物材料学
·
医学工程
✓ 已验证
产品关联
DOI
高影响因子
ACS Applied Energy Materials
·
2021
·
IF 6.024
Liangmiao Zhang,Hui Xia,Fang Xia,Yi Du,Yupeng Wu,Yanfeng Gao
Hydroxypropyl cellulose (HPC) hydrogels exhibit thermal-responsive transparency change due to their temperature-sensitive miscible–immiscible transitions, making them promising thermochromic materials for fabricating energy-saving smart windows. However, their transition temperatures, named lower critical solution temperature (LCST), are too high for building window applications, and it is also challenging to reduce LCST to comfortable room temperature range (e.g., 26–28 °C) in hot seasons. In this work, we report smart windows prepared using poly(acrylic acid) (PAA)-modified HPC hydrogels and demonstrate that the LCST of the resulting HPC/PAA hybrid hydrogels can be effectively tuned by solution pH, from 44 to 10 °C with decreasing pH from 6.0 to 1.0. At pH 2.5, an optimized LCST at 26.5 °C has been achieved. The sandwich-structured smart window, composed of two glass panes and an optimized HPC/PAA hydrogel in between, shows a high visible-light transmittance (Tlum = 90.1%), excellent solar energy modulation (ΔTsol = 47.5%), outstanding heat-shielding performance, and excellent stability after 100 heating and cooling cycles. These optical properties outperform the reported thermosensitive cellulose-based materials, vanadium oxide based smart windows, and other thermosensitive hydrogel-based smart windows. Furthermore, HPC/PAA hydrogels are easy to prepare, nontoxic, biocompatible, low-cost, and environmentally friendly, making them very promising materials for energy-saving and climate-adaptable smart windows.
研究领域:
材料科学
·
化学工程
·
能源效率
·
建筑技术
✓ 已验证
产品关联
DOI
高影响因子
SENSORS AND ACTUATORS B-CHEMICAL
·
2025
·
IF 7.7
Quanming Xu,Feng Zhang,Guizhen Luo,Jiayi Liu,Xue He,Zemiao Wang,Mingdian Yu,Zongwen Wang
The growth of gold nanobipyramids (AuNBPs) provides a superior colorimetric quantification method for point-of-care testing due to their superior growth uniformity, high-resolution multicolor response, and excellent seed storage stability. However, conventional growth methods face significant limitations in sensing applications due to their reliance on a single reductant and stringent acidic conditions. This study systematically investigated the reductant mechanism in AuNBP growth, revealing that the pH-regulated redox potential is crucial for achieving anisotropic AuNBP growth. By employing nine different reductants, the growth pH was expanded from 1.5 to 8.5. Notably, dihydroxybenzene-mediated systems exhibited a slender morphology, reduced reductant consumption, enhanced stability, and comparable analytical performance compared to the conventional growth system. Among these systems, the hydroquinone (HQ)-mediated system was integrated with horseradish peroxidase (HRP)-catalyzed reactions in a pH-compatible manner. By incorporating this integrated system into a commercial HRP immunoassay, a novel multicolor immunosensor was developed for thyroglobulin (Tg) detection. This immunosensor exhibited a distinct nine-color gradient across a ten-fold Tg concentration range (0.1-1.3 ng/mL), achieving a visual detection limit of 0.1 ng/mL and an instrumental detection limit of 29 pg/mL. It accurately detected Tg in human serum with good recoveries of 94.1%-104.8% and signal stability for six hours. The results correlated well with the commercial immunoassay while offering superior visual readout for point-of-care settings. These findings validate the applicability of the HQ-mediated system in converting conventional single-color HRP immunoassays to multicolor immunosensors. Furthermore, expanding reductant selection and pH adaptability in AuNBP growth offers more possibilities for developing versatile pH-flexible multicolor sensors.
研究领域:
纳米技术
·
生物传感器
·
免疫分析
·
分析化学
·
生物医学工程
✓ 已验证
DOI
高影响因子
Nature Communications
·
2024
·Vol. 15
·期 1
·1-13
·
IF 14.7
Li Xuefeng,Liang Xin,Yang Cuiqin,Yan Qiang
Polymer nanoparticles that can sharply sense and detect biological signals in cells are promising candidates for biomedical and theranostic nanomaterials. However, the response ability of current polymer assemblies poorly matches the requirement of trace concentration level (10 −6 ~ 10 −9 mol/L) of cellular biosignals due to their linear signal input-to-function output mode, which impedes their practical applications in vivo. Here we report a kind of nanobowl system with pH-tunable invaginated morphology that can nonlinearly amplify the response abilities toward biosignals by modulating the surface concavity. Compared to conventional spherical nanoparticles, nonspherical nanobowls with a specific concave structure reduce the critical response threshold of polymers by up to 5 orders of magnitude, from millimole to nanomole level, covering most of biosignal concentration windows. Moreover, we find that this nonlinear signal gain effect is originated from the collective impact of a single signal on transitioning the polymer chain aggregation state of individual assemblies, rather than just altering a certain unit or chain. This nonlinear signal-to-response mechanism is potential to solve the tricky problems of probing and sensing endogenous signals with trace physiological concentration.
研究领域:
纳米技术
·
生物医学工程
·
生物传感器
·
材料科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）