Membranes
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2021
·Vol. 11
·期 4
·242
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IF 4.106
Yahui Meng,Yunfeng Cao,Kaifeng Xiong,Li Ma,Wenyuan Zhu,Zhu Long,Cuihua Dong
As an important functional material in food industry, intelligent packaging films can bring great convenience for consumers in the field of food preservation and freshness detection. Herein, we fabricated pH-sensing films employing hydroxypropyl guar (HPG), 1-butyl-3-methylimidazolium chloride (BmimCl), and anthocyanin (Anth). Besides, the effects of adding cellulose nanocrystals (CNC) into the composite films upon the films’ structures and physicochemical properties are elucidated. The addition of CNC promoted more compact film structures. Moreover, CNC dramatically improved several properties of the pH-sensing films, including the distinguishability of their color changes, sensitivity to pH, permeability to oxygen and water vapor, solvent resistance, durability, and low-temperature resistance. These results expand the application range of pH-sensing films containing CNC in the fields of food freshness detection and intelligent packaging.Keywords:pH-sensing film;cellulose nanocrystal;barrier properties;stability
研究领域:
食品科学
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材料科学
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DOI
PubMed
高影响因子
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
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2024
·
IF 7.7
Kejin Yu,Lina Yang,Siyu Zhang,Ning Zhang,Mengxi Xie,Miao Yu
The use of biopolymers as matrices and anthocyanins as pH-sensing indicators has generated increasing interest in freshness detection. Nevertheless, the weak mechanical properties and color stability of biopolymer-based smart packaging systems restrict their practicality. In this study, a nanocellulose hydrogel colorimetric film with enhanced stretchability, antifatigue properties, and color stability was prepared using soy hull nanocellulose (SHNC), polyvinyl alcohol (PVA), sodium alginate (SA), and anthocyanin (Anth) as raw materials. This hydrogel colorimetric film was used to detect beef freshness. The structure and properties (e.g., mechanical, thermal stability and hydrophobicity) of these hydrogel colorimetric films were characterized using different techniques. Fourier-transform infrared spectroscopy revealed the presence of hydrogen and ester bonds in the hydrogel colorimetric films, whereas scanning electron microscopy revealed the fish scale-like and honeycomb network structure of the hydrogel colorimetric films. Mechanical testing demonstrated that the SHNC/PVA/SA/Anth-2 hydrogel colorimetric film exhibited excellent tensile properties (elongation = 261 %), viscoelasticity (storage modulus of 11.25 kPa), and mechanical strength (tensile strength = 154 kPa), and the hydrogel colorimetric film exhibited excellent mechanical properties after repeated tensile tests. Moreover, the hydrogel colorimetric film had high transparency, excellent anti-UV linearity, thermal stability and hydrophobicity, and had displayed visually discernible color response to pH buffer solution and volatile NH 3 by naked eyes, which was highly correlated with the TVB-N and pH values. Notably, the release of anthocyanin in distilled water decreased from 81.23 % to 19.87 %. The designed SHNC/PVA/SA/Anth hydrogel colorimetric films exhibited potential application as smart packaging film or gas-sensing labels in monitoring the freshness of meat products.
研究领域:
材料科学
·
食品科学
·
化学
·
生物技术
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产品关联
DOI
PubMed
高影响因子
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2024
·
IF 7.7
Zhichao Yang,Menglu Wu,Ziqiang Qin,Di Wu,Kunsong Chen
Anthocyanins (ATH), which are plant pigments with potential health benefits, possess antioxidant and natural indicator properties. However, their inherent instability poses a hurdle for practical applications in the food industry. In the present study, we addressed this challenge by encapsulating ATHs in nisin/gelatin (GA)/pullulan (PUL) bioaerogels through freeze-drying. The results showed that the ATH + nisin@GA/PUL bioaerogels exhibited antibacterial activity against S. aureus and E. coli , and pH-responsiveness to the increase in biogenic amines during the spoilage of shrimp, indicating their potential as a freshness indicator. The bioaerogels also displayed sustained antioxidant effects after two months of storage at room temperature. In summary, the ATH + nisin@GA/PUL bioaerogel serves as a stable matrix for preserving the antioxidant activity of ATHs, and facilitates the indication of freshness in perishable foods. This innovative encapsulation technique represents an advancement in the utilization of ATHs in food packaging.
研究领域:
食品科学
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材料科学
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生物技术
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产品关联
DOI
PubMed
高影响因子
ADVANCED FUNCTIONAL MATERIALS
·
2024
·
IF 18.5
Hongxia Xie,Zheng Wang,Ruizi Wang,Qianqian Chen,Aixi Yu,Ang Lu
Chronic diabetic wound repair is a global medical challenge. Developing a hydrogel dressing to effectively promote angiogenesis and detect wound state in diabetic wound management is an unmet medical requirement. Herein, a facile and efficient strategy to prepare self-healing hydrogel with enhanced angiogenesis and real-time monitoring for diabetic wounds is presented, by cross-linking carboxymethyl cellulose (CMC) with precoordinated europium-ethylenediaminetetraacetic acid (Eu-EDTA) complexes. Benefiting from the dynamic and reversible coordination interaction formation, the hydrogel exhibits remarkable injectability and self-healing properties, thus forming efficient coverage in irregular and deep wounds with minimally invasive procedures. Furthermore, the fluorescence of the hydrogel changes linearly with pH value in the range of 4.5–7.5 and enables real-time pH measurement to monitor the wound state. More importantly, the hydrogel can effectively promote the proliferation and migration of endothelial cells and enhance tube formation ability, demonstrating great angiogenesis capacity in tissue remodeling. The in vivo experiments manifested that the hydrogel can enhance angiogenesis by upregulating the expression of angiogenesis-related factors and downregulating matrix metalloproteinase-9 (MMP-9), contributing to granulation tissue formation, collagen deposition, and diabetic wound repair. This work can provide a promising strategy for diagnosis and therapy in clinical diabetic wounds.
研究领域:
生物医学工程
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材料科学
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伤口愈合
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糖尿病管理
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产品关联
DOI
高影响因子
International Journal of Nanomedicine
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2022
·
IF 7.033
Poyu Chen,Chuangwei Zhang,Ping He,Shengyuan Pan,Wenjie Zhong,Yue Wang,Qingyue Xiao,Xinyan Wang,Wenliang Yu,Zhangmin He,Xiang Gao,Jinlin Song
Introduction: The functional reconstruction of periodontal tissue defects remains a clinical challenge due to excessive and prolonged host response to various endogenous and exogenous pro-inflammatory stimuli. Thus, a biomimetic nanoplatform with the capability of modulating inflammatory response in a microenvironment-responsive manner is attractive for regenerative therapy of periodontal tissue. Methods: Herein, a facile and green design of engineered bone graft materials was developed by integrating a biomimetic apatite nanocomposite with a smart-release coating, which could realize inflammatory modulation by "on-demand" delivery of the anti-inflammatory agent through a pH-sensing mechanism. Results: In vitro and in vivo experiments demonstrated that this biocompatible nanoplatform could facilitate the clearance of reactive oxygen species in human periodontal ligament stem cells under inflammatory conditions via inhibiting the production of endogenous proinflammatory mediators, in turn contributing to the enhanced healing efficacy of periodontal tissue. Moreover, this system exhibited effective antimicrobial activity against common pathogenic bacteria in the oral cavity, which is beneficial for the elimination of exogenous pro-inflammatory factors from bacterial infection during healing of periodontal tissue. Conclusion: The proposed strategy provides a versatile apatite nanocomposite as a promising "inflammation scavenger" and propels the development of intelligent bone graft materials for periodontal and orthopedic applications.
研究领域:
牙科材料
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组织工程
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纳米技术
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炎症生物学
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再生医学
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产品关联
DOI
PubMed
高影响因子
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