MICROPOROUS AND MESOPOROUS MATERIALS
·
2020
·
IF 4.551
Haijie Li,Qingshan Miao,Yali Chen,Mingyuan Yin,Hao Qi,Meichen Yang,Qiliang Deng,Shuo Wang
In this study, carbon spheres (CS) with ideal particle sizes (~700 nm) and regular morphology were prepared by extending the Stöber method followed by oxidative modification of nitric acid to obtain carbon spheres (MCS) with abundant carboxyl and nitryl functional groups. Characterisation by SEM, BET, XRD , Raman spectroscopy , FTIR, XPS, and elemental analysis confirmed that these materials possessed regular morphology, large specific surface area (636 m 2 /g for CS and 339 m 2 /g for MCS), a good degree of graphitisation and many carboxyl groups. Because of abundant functional groups, MCS showed excellent adsorption properties for cationic targets (paraquat (PQ), chrysoidine G (CG) and malachite green (MG)), where the maximum adsorption capacities for PQ, CG and MG were 134.63, 299.44 and 326.93 mg/g, respectively. Compared with the linearity of Langmuir, Freundlich, Temkin and Dubinin-Radushkevich isotherm models and the pseudo-first-order, pseudo-second-order, Elovich and intra-particle diffusion kinetics models, the adsorption models for PQ, CG and MG were best represented by the Temkin, Langmuir, and Freundlich isotherms, respectively, and the adsorption kinetics all fitted well with the Elovich model. Moreover, the good regeneration demonstrated in this study (the adsorption capacity remained at more than 80% after five cycles) makes MCS an outstanding candidate for water purification .
研究领域:
环境科学
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材料科学
✓ 已验证
产品关联
DOI
高影响因子
SENSORS AND ACTUATORS B-CHEMICAL
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2015
·
IF 4.097
Jia Tu,Liangliang Xiao,Yingfang Jiang,Qingyuan He,Shiguo Sun,Yongqian Xu
Paraquat (PQ) is one of an effective herbicides but it has extremely toxic effects on animals and humans. It is of great importance to selectively detect PQ with fluorescence response. The first “off–on” fluorescent method based on mechanism of surfactant-controlled aggregate–deaggregate of squaraines (SQ) for paraquat (PQ) recognition in near infrared region was constructed. In this approach, remote-controlled regulation endows unique advantages to fulfill the turn-on response to electron-deficient featured PQ which prefers to quench all reported fluorophores through electron transfer. The assembled system can selectively recognize PQ over other herbicides. The detection limit was calculated to be 95.7 μg L −1 (3.72 × 10 −7 M), which is lower than that of value (200 μg L −1 ) recommended by the US Environmental Protection Agency (EPA). In addition, the system can be used for PQ detection in real sample.
研究领域:
分析化学
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环境科学
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毒理学
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产品关联
DOI
高影响因子
MICROCHIMICA ACTA
·
2020
·Vol. 187
·期 10
·1-10
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IF 6.232
Yao Jianmei,Zhang Lingxue,Ran Jinfeng,Wang Shasha,Dong Nan
Molecularly imprinted stir-bar coatings were created based on a hydroxylcucurbit[7]uril–paraquat inclusion complex. The inclusion complex that contained paraquat (PQ) as a template and monohydroxylcucurbit[7]uril ((OH)Q[7]) as a monomer was preassembled mainly through cavity inclusion interaction of (OH)Q[7] to form a one-dimensional self-assembly structure. The inclusion complex was anchored chemically on the surface of a glass stir bar with hydroxy-terminated poly(dimethylsiloxane) by the sol–gel technique to obtain a molecularly imprinted polymer-coated stir bar (MIP-SB). The molecularly imprinted coating showed specific adsorption for cationic PQ in aqueous media. Other quaternary amine compounds with a similar structure that coexisted in the solution, such as ethyl-viologen, diquat, and difenzoquat, were almost not extracted by the prepared MIP-SB. The sorptive capacity of the MIP-SB for PQ was nearly four times that of the non-imprinted stir bar (NIP-SB). The recognition mechanism indicated that the selectivity and extraction capacity resulted mainly from the imprinted cavity in the polymer that was formed by a one-dimensional assembly structure consisting of the (OH)Q[7]–PQ inclusion complex. The imprinted cavity was complementary to the PQ in shape, size, and functionality. A method to determine PQ in environmental water and vegetable samples was developed by combining MIP-SB sorptive extraction with HPLC-UV. The linear range was from 100 to 10,000 ng L −1 with a 8.2 ng L −1 detection limit for water samples and 0.02–0.85 mg kg −1 with a 0.005 mg kg −1 detection limit for vegetable samples. The limit of detection for both samples was lower than the EU-established maximum residual levels and that of other previously reported methods. The average recoveries were 70.0–96.1% with a relative standard deviation ≤ 7.6%, which showed the successful application in real sample analysis.
Molecularly imprinted stir-bar coatings were created based on a hydroxylcucurbit[7]uril–paraquat (PQ) inclusion complex, which showed a specific recognition toward cationic PQ. A method to determine PQ in environmental water and vegetable samples was established by combining MIP-SB sorptive extraction with HPLC-UV.
研究领域:
环境科学
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分析化学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Materials Science & Engineering C-Materials for Biological Applications
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2020
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IF 5.88
Zhong-Hui Wang,Yun-Fei Zhang,Xiao-Wen Sun,Ying-Jie Li,You-Ming Zhang,Tai-Bao Wei,Hong Yao,Qi Lin
Paraquat, one of non-selective herbicides, is widely used in agricultural production. However, it can cause death of people or animals quickly owing to its fatal toxicity. In the present work, for efficient separation and removal of the paraquat, a concept “employ collaboration effect to enhance the Host-Guest interactions” was rationally introduced into the design of paraquat adsorbent material. According to this concept, a novel linear tri-pillar[5]arene-based acceptor molecule was synthesized. Interestingly, the acceptor shows outstanding adsorption properties for paraquat through the collaboration effect of the adjacent pillar[5]arene moieties in the linear tri-pillar[5]arene acceptor. Compared with other adsorbents such as activated carbon and single-pillar[5]arene-based adsorbent materials, the linear tri-pillar[5]arene acceptor shows higher adsorption rate for paraquat. Additionally, the linear tri-pillar[5]arene acceptor was applied to adsorb the commercial pesticide paraquat sample in water with adsorption rate of 98%. Therefore, the linear tri-pillar[5]arene acceptor could serve as a paraquat adsorbent material and convey greatly potential application in the field of removal of paraquat. The concept “employ collaboration effect to enhance the Host-Guest interactions” is a useful way for the development of adsorption materials.
研究领域:
环境科学
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化学
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产品关联
DOI
PubMed
高影响因子
NANOTECHNOLOGY
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2019
·Vol. 30
·期 28
·285502
·
IF 3.399
Fen-Ying Kong,Rong-Fang Li,Lei Yao,Zhong-Xia Wang,Heng-Ye Li,Wen-Juan Wang,Wei Wang
In this paper, a novel electrochemical sensor based on Au nanoparticles/8-aminoquinoline functionalized graphene oxide (AuNPs/GAQ) nanocomposite was developed and tested for the first time for detection of paraquat (PQ). The morphology and composition of AuNPs/GAQ nanocomposite were characterized by various techniques, including transmission electron microscopy, Fourier transform infrared spectroscopy, Raman spectroscopy, and x-ray photoelectron spectroscopy. Cyclic voltammetry and differential pulse voltammetry were utilized to investigate the electrochemical performances of AuNPs/GAQ nanocomposite modified glassy carbon electrode. The obtained modified electrode exhibited excellent electrocatalytic activity towards detection of PQ. Under the optimized conditions, the proposed sensor showed low detection limit (6 nM, S/N = 3), wide linear range (0.02–24 μM), high selectivity and good stability. In addition, it was successfully applied for detection of PQ in natural water samples with satisfactory results.
研究领域:
分析化学
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环境科学
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纳米技术
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产品关联
DOI
PubMed
高影响因子
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
·
2018
·
IF 2.88
Zuzhi Zhao,Fengwei Zhang,Zipin Zhang
Development of a technically simple yet effective method for paraquat (PQ) detection is of great importance due to its high clinical and environmental relevance. In this study, we developed a pyranine-based fluorescent “turn-off” method for PQ sensing based on pyranine-PQ interaction. We investigated the dependence of analytical performance of this method on the experimental conditions, such as the ion strength, medium pH, and so on. Under the optimized conditions, the method is sensitive and selective, and could be used for PQ detection in real-world sample. This study essentially provides a readily accessible fluorescent system for PQ sensing which is cheap, robust, and technically simple, and it is envisaged to find more interesting clinical and environmental applications.
研究领域:
分析化学
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环境科学
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临床化学
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产品关联
DOI
PubMed
高影响因子
MICROCHIMICA ACTA
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2020
·Vol. 187
·期 6
·1-8
·
IF 6.232
Liang Pei,Cao Yu,Dong Qianmin,Wang Dan,Zhang De,Jin Shangzhong,Yu Zhi,Ye Jiaming,Zou Mingqiang
Simple and traditional hydrothermal fabrication of a novel balsam pear-shaped CuO with high SERS enhancement is presented. XRD (X-ray diffraction), SEM (scanning electronic microscopy), TEM (transmission electron microscope), HRTEM (high-resolution transmission electron microscope), UV-Vis, and Raman are adopted to ensure that this balsam pear-shaped CuO with dense nanoparticle protuberance is successfully prepared. The LOD of this CuO SERS substrate is 4.79 μg L −1 with R6G as molecular probe. By using DFT (density functional theory) calculation and FDTD (finite difference time domainmethod) simulation, both EM (electromagnetic enhancement) and CM (chemical enhancement) mechanisms are investigated, and the results show that these two-enhancement mechanisms can coexist in this balsam pear-shaped CuO. Finally, the prepared substrate has been applied for the determination of trace levels of paraquat in solution , and results show that its LOD for paraquat is 275 μg L −1 (optimum Raman band: 1646 cm −1 Raman shift), which is better than the government standard in China. A dexterous and facile way for fabrication of CuO SERS-active substrates with low cost and high performance, quite promising in detection of chemically hazardous substances and pesticide residue is provided.
Graphical abstract
研究领域:
分析化学
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环境科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
BIOLOGICAL & PHARMACEUTICAL BULLETIN
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2015
·Vol. 38
·期 7
·1049-1053
·
IF 1.828
Zhiyi Wang,Jianshe Ma,Meiling Zhang,Congcong Wen,Xueli Huang,Fa Sun,Shuanghu Wang,Lufeng Hu,Guanyang Lin,Xianqin Wang
Paraquat is one of the most widely used herbicides in the world and is highly toxic to humans and animals. In this study, we developed a serum metabolomic method based on GC/MS to evaluate the effects of acute paraquat poisoning on rats. Pattern recognition analysis, including both principal component analysis and partial least squares-discriminate analysis revealed that acute paraquat poisoning induced metabolic perturbations. Compared with the control group, the level of octadecanoic acid, L-serine, L-threonine, L-valine, and glycerol in the acute paraquat poisoning group (36 mg/kg) increased, while the levels of hexadecanoic acid, D-galactose, and decanoic acid decreased. These findings provide an overview of systematic responses to paraquat exposure and metabolomic insight into the toxicological mechanism of paraquat. Our results indicate that metabolomic methods based on GC/MS may be useful to elucidate the mechanism of acute paraquat poisoning through the exploration of biomarkers.
研究领域:
毒理学
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分析化学
✓ 已验证
DOI
PubMed
高影响因子
ENVIRONMENTAL POLLUTION
·
2017
·
IF 5.099
Xiaoji Fan,Jiahui Xu,Michel Lavoie,W.J.G.M. Peijnenburg,Youchao Zhu,Tao Lu,Zhengwei Fu,Tingheng Zhu,Haifeng Qian
Carbon nanotubes can be either toxic or beneficial to plant growth and can also modulate toxicity of organic contaminants through surface sorption . The complex interacting toxic effects of carbon nanotubes and organic contaminants in plants have received little attention in the literature to date. In this study, the toxicity of multiwall carbon nanotubes (MWCNT, 50 mg/L) and paraquat (MV, 0.82 mg/L), separately or in combination, were evaluated at the physiological and the proteomic level in Arabidopsis thaliana for 7–14 days. The results revealed that the exposure to MWCNT had no inhibitory effect on the growth of shoots and leaves. Rather, MWCNT stimulated the relative electron transport rate and the effective photochemical quantum yield of PSII value as compared to the control by around 12% and lateral root production up to nearly 4-fold as compared to the control. The protective effect of MWCNT on MV toxicity on the root surface area could be quantitatively explained by the extent of MV adsorption on MWCNT and was related to stimulation of photosynthesis, antioxidant protection and number and area of lateral roots which in turn helped nutrient assimilation. The influence of MWCNT and MV on photosynthesis and oxidative stress at the physiological level was consistent with the proteomics analysis, with various over-expressed photosynthesis-related proteins (by more than 2 folds) and various under-expressed oxidative stress related proteins (by about 2–3 folds). This study brings new insights into the interactive effects of two xenobiotics (MWCNT and MV) on the physiology of a model plant.
研究领域:
植物学
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环境科学
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毒理学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Theranostics
·
2019
·
IF 8.063
Xiangjun Zhang,Xiaoqiu Xu,Shengke Li,Lanlan Li,Jianxiang Zhang,Ruibing Wang
Accidental or suicidal ingestion of the world's most widely used herbicide, paraquat (PQ), may result in rapid multi-organ failure with a 60% fatality rate due to the absence of an effective detoxification solution. Effective, specific antidotes to PQ poisoning have been highly desired. Methods: The binding constant of PQ and a synthetic receptor, cucurbit[7]uril (CB[7]), was first determined in various pH environments. The antidotal effects of CB[7] on PQ toxicity were firstly evaluated with in-vitro cell lines. With in-vivo mice models, the pharmacokinetics and the biodistribution of PQ in major organs were determined to evaluate the influence of CB[7] on the oral bioavailability of PQ. Major organs' injuries and overall survival rates of the mice were systemically examined to evaluate the therapeutic efficacy of CB[7] on PQ poisoning. Results: We demonstrate that CB[7] may complex PQ strongly under various conditions and significantly reduce its toxicity in vitro and in vivo . Oral administration of PQ in the presence of CB[7] in a mouse model significantly decreased PQ levels in the plasma and major organs and alleviated major organs' injuries, when compared to those of mice administered with PQ alone. Further studies indicated that oral administration of CB[7] within 2 h post PQ ingestion significantly increased the survival rates and extended the survival time of the mice, in contrast to the ineffective treatment by activated charcoal, which is commonly recommended for PQ decontamination. Conclusion: CB[7] may be used as a specific oral antidote for PQ poisoning by strongly binding with PQ and inhibiting its absorption in the gastrointestinal tracts.
研究领域:
毒理学
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药学
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化学
✓ 已验证
DOI
PubMed
高影响因子
CHEMOSPHERE
·
2020
·
IF 5.778
Haijie Li,Hao Qi,Mingyuan Yin,Yujie Chen,Qiliang Deng,Shuo Wang
Paraquat (PQ) pollution has become an increasing seriously threat to the ecological environment. Thus, it is vital to study novel adsorption materials capable of removing PQ. Modified carbon tubes (MCT-600) were prepared by carbonizing the seed hair fibers of Metaplexis japonica at 600 °C and further modifying with nitric acid . The MCT-600 was found to possess a regular morphology, a good graphitization degree and an abundance of carboxyl functional groups. Moreover, this materil exhibits excellent adsorption performance for paraquat (PQ), such as a fast adsorption rate (adsorption equilibrium within 20 min), large adsorption capacity (218.61 mg g −1 ) and good regeneration ability (reused more than 5 times). The adsorption process for PQ onto MCT-600 was found to be well matched to a Langmuir isotherm and pseudo-second-order kinetics model. Owing to its unique surface properties, green raw material source and simple preparation process, MCT-600 shows potential as an outstanding candidate for PQ removal from water.
研究领域:
环境科学
·
材料科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Frontiers in Physiology
·
2020
·
IF 3.367
Zhang Zhen-Dong,Huang Mei-Zhou,Yang Ya-Jun,Liu Xi-Wang,Qin Zhe,Li Shi-Hong,Li Jian-Yong
Aspirin eugenol ester (AEE) is a new potential drug with anti-inflammatory and antioxidant stress pharmacological activity. Paraquat (PQ) is an effective and commercially important herbicide that is widely used worldwide. However, paraquat is highly toxic and can cause various complications and acute organ damage, such as liver, kidney and lung damage. The purpose of this study was to investigate whether AEE has a protective effect on hepatotoxicity induced by PQ in vivo and in vitro. Cell viability, apoptosis rate, mitochondrial function and intracellular oxidative stress were detected to evaluate the protective effect of AEE on PQ-induced BRL-3A (normal rat hepatocytes) cytotoxicity in vitro. In vivo, AEE pretreatment could attenuate oxidative stress and histopathological changes in rat liver induced by PQ. The results showed that AEE could reduce the hepatotoxicity induced by PQ in vivo and in vitro. AEE reduced PQ-induced hepatotoxicity by inhibitingoxidative stress and maintaining mitochondrial function. This study proved that AEE is an effective antioxidant and can reduce the hepatotoxicity of PQ.
研究领域:
药理学
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毒理学
·
肝病学
✓ 已验证
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）