CHEMICAL ENGINEERING & TECHNOLOGY
·
2018
·Vol. 41
·期 6
·1188-1198
·
IF 1.588
Li Wang,Bolin Lian,Weiwei Wu,Yiping Deng,Yanjie Liu,Lingling Wang,Yuanyuan Li,Zijian Wang,Xiuhua Zhao
Ellagic acid (EA) was produced from pomegranate husk by extraction of tannins followed by acid hydrolysis and purified by antisolvent recrystallization. Response surface methodology, based on a five-level, four-variable central composite design, was employed to find the optimum purification conditions. Under these conditions, high purity and yield of EA was obtained in close agreement with the predicted values by the model. Analyzes of surface morphology and in vitro percutaneous absorption experiments of EA let conclude that the granule morphology of the purified EA was significantly different from the crude EA, and its particle size was much smaller than that of the crude EA. Evaluation in vitro demonstrated that the permeation rate of the purified EA was higher compared with the crude EA.
研究领域:
植物化学
·
药物化学
·
食品科学
✓ 已验证
DOI
高影响因子
IONICS
·
2016
·Vol. 23
·期 4
·985-996
·
IF 2.119
Sun Kanjun,Li Jindan,Peng Hui,Feng Enke,Ma Guofu,Lei Ziqiang
Nitrogen-doped porous activated carbons (N-PHACs) have been successfully synthesized using pomegranate husk as carbon precursor via ZnCl 2 -activation carbonization and subsequent urea-assisted hydrothermal nitrogen-doping method. The obtained N-PHACs possesses abundant mesoporous structure, high specific surface area (up to 1754.8 m 2 g −1 ), pore volume (1.05 cm 3 g −1 ), and nitrogen-doping content (4.51 wt%). Besides, the N-PHACs-based material showed a high specific capacitance of 254 F g −1 at a current density of 0.5 A g −1 and excellent rate performance (73% capacitance retention ratio even at 20 A g −1 ) in 2 M KOH aqueous electrolyte, which is attributed to the contribution of double-layer capacitance and pseudocapacitance. The assembled N-PHACs-based symmetric capacitor with a wide operating voltage range of 0–1.8 V exhibits a maximum energy density of 15.3 Wh kg −1 at a power density of 225 W kg −1 and superior cycle stability (only 6% loss after 5000 cycles) in 0.5 M Na 2 SO 4 aqueous electrolyte. These exciting results suggest that the novel N-doping porous carbon material prepared by a green and low-cost design strategy has a potential application as high-performance electrode materials for supercapacitors.
研究领域:
材料科学
·
电化学
·
纳米能源
·
储能材料
·
碳材料
✓ 已验证
DOI
高影响因子
JOURNAL OF SEPARATION SCIENCE
·
2016
·Vol. 39
·期 10
·1963-1970
·
IF 2.741
Guang-Ying Sun,Chao Wang,Yu-Qin Luo,Yong-Xin Zhao,Jian Yang,Zhao-Sheng Liu,Haji Akber Aisa
The combination of molecular crowding and virtual imprinting was employed to develop a cost-effective method to prepare molecularly imprinted polymers. By using linear polymer polystyrene as a macromolecular crowding agent, an imprinted polymer recognizable to punicalagin had been successfully synthesized with punicalin as the dummy template. The resulting punicalin-imprinted polymer presented a remarkable selectivity to punicalagin with an imprinting factor of 3.17 even at extremely low consumption of the template (template/monomer ratio of 1:782). In contrast, the imprinted polymer synthesized without crowding agent, did not show any imprinting effect at so low template amount. The imprinted polymers made by combination of molecular crowding and virtual imprinting can be utilized for the fast separation of punicalagin from pomegranate husk extract after optimizing the protocol of solid-phase extraction with the recovery of 85.3 ± 1.2%.
研究领域:
分析化学
·
天然产物分离纯化
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产品关联
DOI
PubMed
高影响因子
JOURNAL OF CHROMATOGRAPHY A
·
2017
·
IF 3.981
Guangying Sun,Yanfang Liu,Hasanjan Ahat,Aijin Shen,Xinmiao Liang,Xingya Xue,Yuqin Luo,Jian Yang,Zhao-Sheng Liu,Haji Akber Aisa
In this study, “two dimensional” molecularly imprinted solid-phase extraction (2D-MIP-SPE) of semi-preparative grade was constructed to fast purify ellagitannins in pomegranate husk extract with the help of crystallization and reverse-phase liquid chromatgoraphy (RPLC). Ellagic acid and punicalagin imprinted polymers were synthesized in batch mode and two semi-preparative MIP-SPE columns were individually packed. After investigaing “functional complementation”, 2D-MIP-SPE was constructed using ellagic acid MIP and punicalagin MIP-SPE as the first and second dimension, respectively. Then, pomegranate husk extract was fast divided into four fractions individually enriching in ellagic acid, granatin A, punicalagin and ellagic acid glucoside by 2D-MIP-SPE. With the aid of crystallization and RPLC, ellagic acid (13.5 mg) and punicalagin (53.4 mg) were fast obtained in 30 min. Ellagic acid glucoside was purified to the purity near 100% with a recovery of 86.1%. Granatin A (92%) was directly obtained by 2D-MIP-SPE with the recovery of 81.8%. All above indicated that 2D-MIP-SPE was highly efficient in natural product purification. The concept of “functional complementation” was expected to be a useful tool in the construction of 2D-MIP-SPE.
研究领域:
分析化学
·
天然产物化学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）