Scientific Reports
·
2023
·Vol. 13
·期 1
·1-14
·
IF 4.6
Alishiri Mahsa,Gonbadi Maryam,Narimani Mehdi,Abdollahi Seyyed Amirreza,Shahsavaripour Negin
The contamination of the aquatic environment with antibiotics is among the major and developing problems worldwide. The present study investigates the potential of adsorbent magnetite-chitosan nanoparticles (Fe 3 O 4 /CS NPs) for removing trimethoprim (TMP) and sulfamethoxazole (SMX). For this purpose, Fe 3 O 4 /CS NPs were synthesized by the co-precipitation method, and the adsorbent characteristics were investigated using XRD, SEM, TEM, pH zpc , FTIR, and VSM. The effect of independent variables (pH, sonication time, adsorbent amount, and analyte concentration) on removal performance was modeled and evaluated by Box–Behnken design (BBD). The SEM image of the Fe 3 O 4 /CS adsorbent showed that the adsorbent had a rough and irregular surface. The size of Fe 3 O 4 /CS crystals was about 70 nm. XRD analysis confirmed the purity and absence of impurities in the adsorbent. TEM image analysis showed that the adsorbent had a porous structure, and the particle size was in the range of nanometers. In VSM, the saturation magnetization of Fe 3 O 4 /CS adsorbent was 25 emu g −1 and the magnet could easily separate the adsorbent from the solution. The results revealed that the optimum condition was achieved at a concentration of 22 mg L −1 , a sonication time of 15 min, an adsorbent amount of 0.13 g/100 mL, and a pH of 6. Among different solvents (i.e., ethanol, acetone, nitric acid, and acetonitrile), significant desorption of TMP and SMX was achieved using ethanol. Also, results confirmed that Fe 3 O 4 /CS NPs can be used for up to six adsorption/desorption cycles. In addition, applying the Fe 3 O 4 /CS NPs on real water samples revealed that Fe 3 O 4 /CS NPs could remove TMP and SMX in the 91.23–95.95% range with RSD (n = 3) < 4. Overall, the Fe 3 O 4 /CS NPs exhibit great potential for removing TMP and SMX antibiotics from real water samples.
研究领域:
环境科学
·
材料科学
·
药学
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产品关联
DOI
PubMed
高影响因子
SCIENCE OF THE TOTAL ENVIRONMENT
·
2024
·
IF 8.2
Tao Ai,Siyu Yao,Yuanyuan Yu,Kai Peng,Ling Jin,Xifen Zhu,Haijun Zhou,Jiahui Huang,Jianteng Sun,Lizhong Zhu
Sulfonamide antibiotics, extensively used in human and veterinary therapy, accumulate in agroecosystem soils through livestock manure and sewage irrigation. However, the interaction between sulfonamides and rice plants remains unclear. This study investigated the transformation behavior and toxicity of sulfamethoxazole (SMX) and its main metabolite, N4-acetyl-sulfamethoxazole (NASMX) in rice. SMX and NASMX were rapidly taken up by roots and translocated acropetally. NASMX showed higher accumulating capacity, with NASMX concentrations up to 20.36 ± 1.98 μg/g (roots) and 5.62 ± 1.17 μg/g (shoots), and with SMX concentrations up to 15.97 ± 2.53 μg/g (roots) and 3.22 ± 0.789 μg/g (shoots). A total of 18 intermediate transformation products of SMX were identified by nontarget screening using Orbitrap-HRMS, revealing pathways such as deamination, hydroxylation, acetylation, formylation, and glycosylation. Notably, NASMX transformed back into SMX in rice, a novel finding. Transcriptomic analysis highlights the involvements of cytochrome P450 (CYP450), acetyltransferase (ACEs) and glycosyltransferases (GTs) in these biotransformation pathways. Moreover, exposure to SMX and NASMX disrupts TCA cycle, amino acid, linoleic acid, nucleotide metabolism, and phenylpropanoid biosynthesis pathways of rice, with NASMX exerting a stronger impact on metabolic networks. These findings elucidate the sulfonamides' metabolism, phytotoxicity mechanisms, and contribute to assessing food safety and human exposure risk amid antibiotic pollution.
研究领域:
环境科学
·
植物生理学
·
药理学
·
分子生物学
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毒理学
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产品关联
DOI
PubMed
高影响因子
JOURNAL OF HAZARDOUS MATERIALS
·
2026
·
IF 10.6
Jie Chen,Peizeng Yang,Kai Wu,Yuefei Ji,Xuezhu Zhu,Jing Chen,Junhe Lu
The cryosphere plays a critical role in global biogeochemical cycles, however, the kinetic behavior and environmental fate of pollutants in ice remain insufficiently understood. In this study, we investigated for the first time the effect of freezing and syringic acid (SYA) on the transformation of sulfamethoxazole (SMX) mediated by manganese dioxide (MnO 2 ) under slightly acidic conditions. Freezing significantly accelerated SMX removal, reached 23.1% within 4 h in the absence of SYA, whereas this removal was negligible in aqueous solution. The presence of SYA further promoted the transformation of SMX, achieving 81.3% removal in ice compared to 46.5% in aqueous solution. We proposed that this enhanced transformation was driven by synergistic effects of solute aggregation and localized pH drop between ice crystals, arising from the freeze-concentration effect. These processes collectively elevated the redox activity of MnO 2 , and significantly promoted the rate of SMX transformation. Under this condition, SYA was first oxidized by MnO 2 to quinone, which subsequently underwent nucleophilic addition with SMX to form coupling products. These findings underscore that natural ice matrices serve as a potential medium for organic matter transformation, thereby exerting a profound influence on the environmental fate of sulfonamide antibiotics in polar and cold regions.
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DOI
PubMed
高影响因子
CHEMOSPHERE
·
2019
·
IF 5.108
Hai Chen,Jianlong Wang
In this study, Fe 3 O 4 /Co 3 O 4 composites were prepared and applied in the catalytic ozonation of sulfamethoxazole (SMX). Various parameters including initial solution pH, Fe 3 O 4 /Co 3 O 4 composites dose, O 3 dose and SMX concentration were investigated. Results showed that Fe 3 O 4 /Co 3 O 4 composites could significantly improve the mineralization of SMX by catalytic ozonation system and a synergic effect between Fe 3 O 4 and Co 3 O 4 was observed. Only about 16% total organic carbon (TOC) could be removed in 60 min by single ozonation under the condition of 20 mg/L SMX, 6.0 mg/min O 3 , pH 5.1 and room temperature, While in the presence of 0.10 g/L Fe 3 O 4 /Co 3 O 4 composites at the same conditions, 60% TOC removal were obtained by catalytic ozonation process. SMX could be degradation by O 3 rapidly and the removal was not significantly affected by the changing parameters. However, those operating parameters exerted different effects on SMX mineralization. Furthermore, the generation of hydroxyl radicals ( OH) and the utilization efficiency of O 3 would increase with the addition of Fe 3 O 4 /Co 3 O 4 composites. The quenching experiments indicated that OH might account for the enhancement of SMX mineralization and the mechanism of catalytic ozonation was proposed. Additionally, the intermediates were detected by using a high-performance liquid chromatography-mass spectrometry (LC-MS), from which some plausible transformation pathways were proposed.
研究领域:
环境科学
·
化学工程
✓ 已验证
DOI
高影响因子
Environmental Science-Water Research & Technology
·
2022
·Vol. 8
·期 12
·3007-3018
·
IF 5.819
Yanning Lv,Minghao Sui,Xinyuan Lv,Jingni Xie
Antibiotics, as emerging trace organic pollutants in water sources, pose a potential threat to drinking water safety. Piezoelectric catalysis is an innovative and green advanced oxidation technology in which mechanical energy can be converted into electrical energy or chemical energy, even without the addition of chemical reagents. Thus, piezoelectric catalysis can be used to degrade trace organic pollutants in water. However, such studies have seldom been reported. In this work, the performance of a typical piezoelectric catalyst, i.e., BaTiO3 (BTO), with mechanical energy from ultrasound (US) for the piezoelectric degradation of sulfamethoxazole (SMX) in water was studied systematically. The results showed that the BTO/US piezoelectric catalytic system exhibited the efficient degradation of SMX. The operating parameters in the BTO/US system were optimized for the effective degradation of SMX, and the influencing factors (initial concentration of SMX, pH, and the coexisting constituents in water) affecting the degradation of SMX by BTO/US were investigated. In addition, the reaction mechanism of the piezoelectric system was investigated via identifying the active species generated in BTO/US through quenching tests and electron paramagnetic resonance analysis. It was found that US could activate BTO to generate hydroxyl radicals (˙OH), superoxide radicals (˙O2−), and singlet oxygen (1O2), thus greatly enhancing the SMX degradation efficiency. Overall, the present study demonstrates that the BTO/US system is a promising form of technology for the green degradation of trace organic pollutants in water.
研究领域:
环境科学
·
催化化学
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DOI
高影响因子
CHEMOSPHERE
·
2020
·
IF 5.778
Shixiang Wang,Guangsheng Wang,Yongsheng Fu,Yiqing Liu
Exploration of novel advanced oxidation systems with high efficiency toward radical generation is of significant importance due to the extensive and versatile application of reactive species in the wastewater treatment . Herein we report a simple UV-catalytic homogeneous advanced oxidation system (UV/Fe 3+ /hydrogen sulfite (BS)), which is capable of generating abundant radicals (e.g., SO 3 - , SO 4 - , SO 5 - and HO ) in the aqueous environment. Sulfamethoxazole (SMX) degradation using this system was tested. Results indicated that SMX could be degraded effectively by UV/Fe 3+ /BS and sulfate radical (SO 4 - ) and hydroxyl radical (HO • ) were verified to be presented in this system and be contributive to SMX removal. The acidic pH (4.0) and a low BS/Fe 3+ ratio (10:1) were suitable for SMX degradation. The presence of fulvic acid (FA) and HCO 3 − strongly inhibited the degradation of SMX, but obvious acceleration was observed in the presence of NO 3 − due to its contribution on additional radical generation by photosensitization. Based on the detected transformation products through LC-MS analysis, the degradation pathway of SMX by UV/Fe 3+ /BS was proposed including hydroxylation and bond cleavage.
研究领域:
环境科学
·
化学工程
✓ 已验证
产品关联
DOI
PubMed
高影响因子
CHEMOSPHERE
·
2019
·
IF 5.108
Xuan Guo,Can Chen,Jianlong Wang
Microplastics and sulfamethoxazole (SMX) are ubiquitous in aquatic environment. In this study, we investigated the sorption of SMX onto six types of microplastics (polyamide (PA), polyethylene (PE), polyethylene terephthalate (PET), polystyrene (PS), polyvinyl chloride (PVC) and polypropylene (PP)). The sorption rate and mass transfer steps of SMX was studied by using the phenomenological kinetics models. The effect of pH and salinity on SMX sorption was examined. The results showed that the sorption of SMX onto microplastics reached equilibrium within 16 h. The external mass transfer was the slowest sorption step. The linear and Freundlich isotherms fitted well the sorption equilibrium data. PA had the highest sorption capacity (2.36 mg g −1 at SMX concentrations of 12 mg L −1 ), with high distribution coefficient ( K d ) value (284 L kg −1 ). The K d values of PE, PS, PET, PVC, and PP ranged from 22.2 to 30.9 L kg −1 . The sorption capacity of SMX decreased with increase of pH and salinity in the solution.
研究领域:
环境科学
·
生态学
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产品关联
DOI
PubMed
高影响因子
SEPARATION AND PURIFICATION TECHNOLOGY
·
2019
·
IF 5.107
Shixiang Wang,Hongbin Wang,Yiqing Liu,Yongsheng Fu
Peracetic acid (PAA), a green disinfectant, has been widely used in the wastewater treatment. Here, a novel heterogeneous advanced oxidation process (Fe 2+ -zeolite/PAA) capable of generating hydroxyl radical was developed to remove sulfamethoxazole (SMX) from the contaminated water. The influences of various operational parameters including the initial pH, dosages of PAA and Fe 2+ -zeolite and water matrix on the removal of SMX were investigated. The complete removal of SMX occurred at mild pH condition (around 7.0) within 50 min. With the increase in PAA concentration or Fe 2+ -zeolite dosage, the degradation of SMX both enhanced. Presence of metal cations, inorganic anions and natural organic matter in the reaction system had a different degree of influence on SMX degradation. Based on the radical scavenging experiment, hydroxyl radical was proved to be mainly responsible for SMX oxidation. The degradation mechanism of SMX by Fe 2+ -zeolite/PAA was tentatively proposed showing three different reaction pathways including hydroxylation, nitrosation and bond cleavage according to the detected transformation products.
研究领域:
环境科学
·
化学工程
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DOI
高影响因子
JOURNAL OF HAZARDOUS MATERIALS
·
2020
·
IF 9.038
Hai Chen,Jianlong Wang
In this study, the degradation and mineralization of sulfamethoxazole (SMX) by ozonation and ionizing radiation were investigated respectively, and the performance of the combined process of ozonation and ionizing radiation was evaluated. Results showed that complete degradation of SMX could be obtained by ozonation in 12 min or by ionizing radiation with the absorbed dose of 1.5 kGy. However, the mineralization of SMX was very limited in ozonation and ionizing radiation system, TOC removal efficiency was less than 15% and 27% in single-ozonation and single-radiation process, respectively. The combination of ozonation and radiation process obviously enhanced the mineralization of SMX, TOC removal efficiency increased to 65.7%. Moreover, the ozonation-radiation process also exhibited good performance in the mineralization of sulfamethazine (SMT) and sulfanilamide (SM), suggesting a good application prospect of the combined process in treating wastewater contaminated with antibiotics. In addition, some different intermediate products were identified during SMX degradation in ozonation process and ionizing radiation process by a high-performance liquid chromatography-mass spectrometry (LC-MS), and possible pathways of SMX degradation by ozonation and radiation were proposed.
研究领域:
环境科学
·
化学工程
✓ 已验证
DOI
高影响因子
RADIATION PHYSICS AND CHEMISTRY
·
2016
·
IF 1.207
Libing Chu,Jianlong Wang
Activated carbon (AC) has been widely used for reclamation and reuse of the effluent of wastewater treatment plant to further remove the emerging contaminants, such as PPCPs in recent years. How to regenerate the exhausted AC effectively and economically is still a challenge. In the present study, the regeneration of AC exhausted with SMX was performed by gamma irradiation to simultaneously recover the spent AC and degrade the pollutants. The results showed that the adsorption of SMX onto AC can be described by the Langmuir isotherm and the adsorption capacity was about 417 mg/g. SMX can be removed rapidly when exposed to gamma irradiation, with the initial concentration of 100 mg/L, more than 99% of SMX was removed at 5.0 kGy, while an extremely high dose (150 kGy) was needed to reach 80% mineralization ratio. The regeneration efficiency was about 21–30% at 50–200 kGy. The absorbed SMX and the intermediates formed during gamma irradiation were released into aqueous solution from AC and mineralized, leading to the partial regeneration of the adsorption capacity of AC. Further studies are needed to optimize the experimental conditions to increase the regeneration efficiency.
研究领域:
环境科学
·
水处理
·
辐射化学
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产品关联
DOI
高影响因子
BIOCHEMICAL ENGINEERING JOURNAL
·
2024
·
IF 3.7
Oluwadamilola Oluwatoyin Hazzan,Collins Chimezie Elendu,Claude Kiki,Geng Chen,Juvens Sugira Murekezi,Asmamaw Abat Getu,Yong Xiao
Antibiotics like Sulfamethoxazole (SMX) pose a significant threat to public health and environmental well-being. To address this issue, effective strategies are being developed to remove antibiotics from the environment. This study investigates the degradation of SMX with a focus on elucidating the mechanism by which extracellular electron transfer (EET) enhances the efficient degradation of the antibiotic. The results show that SMX was significantly degraded (97 %) by Shewanella oneidensis MR-1 after 120 hours in the presence of a bioelectrochemical system (BES) at a concentration of 1 mg L −1 , compared to the absence of BES (69 %) at the same concentration and time. BES was observed to simultaneously remove pollutants like SMX while generating electricity at this concentration. Proteomic analysis was further employed to clarify the mechanism behind this process. Three key SMX-degrading proteins; S-ribosylhomocysteine lyase (luxS), Deoxyribose-phosphate aldolase (deoC), and Amidohydrolase which mainly participated in C-S cleavage, S-N hydrolysis and isoxazole ring cleavage were identified. The study demonstrates that S. oneidensis MR-1 can promote the generation of Nicotinamide Adenine Dinucleotide and Adenosine Triphosphate and facilitate electron transfer to enhance the efficient degradation of SMX. The findings of this study provide new insights into the correlation mechanism between SMX degradation and EET, ultimately contributing to innovative solutions for environmental remediation.
研究领域:
环境科学
·
微生物学
·
生物技术
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产品关联
DOI
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2020
·
IF 10.652
Yaqun Yu,Yuefei Ji,Junhe Lu,Xiaoming Yin,Quansuo Zhou
In this study, a simple hydrothermal method was used to synthesize Co 3 O 4 -palygorskite composites. Transmission electron microscopy, X-ray spectroscopy and X-ray diffraction analysis showed that Co 3 O 4 nanoparticles with diameters of approximately 3–5 nm were uniformly distributed on the surface of palygorskite fibers. Co 3 O 4 -palygorskite composites were outstanding catalyst for activating peroxymonosulfate (PMS) to degrade the antibiotic sulfamethoxazole (SMX). Complete removal of 30 μM SMX at pH 3–5 was achieved with doses of 0.3 mM PMS and 125 mg/L Co 3 O 4 -palygorskite composites. The composites exhibited higher catalytical activity than unsupported Co 3 O 4 . The removal rate of SMX was accelerated under acidic conditions (pH 3–5), while was significantly inhibited under basic conditions (pH 11–12). Radical quenching tests revealed that SO 4 − and OH were responsible for the degradation. The oxidative degradation was initiated at either isoxazole or aniline moiety of the SMX molecule. Using solid phase extraction-liquid chromatography-time-of-flight-tandem mass spectrometry, a total of six transformation products formed from benzene ring hydroxylation, S-N bond cleavage, aniline moiety oxidation and coupling reactions were identified. Based on the products, three transformation pathways are proposed for the catalytic degradation of SMX in the Co 3 O 4 -palygorskite/PMS system.
研究领域:
环境科学
·
化学工程
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）