ANALYST
·
2021
·Vol. 146
·期 9
·3052-3061
·
IF 4.616
Jie Min,Xiang-Long Qu,Bing Yan
By means of post-synthetic treatment on the UiO-66 derivative with –SO3H, a novel luminescent hybrid material named Tb3+@UiO-66–SO3H has been prepared simply and efficiently. Given its wonderful luminescence properties like intense green emission, a long lifetime, a robust structure and photostability, it is further developed as a fluorescent probe for the sensing of trans,trans-muconic acid (tt-MA, a biomarker of benzene) and Fe3+, which are closely related to human health. Notably, Tb3+@UiO-66–SO3H shows an outstanding recognition ability for Fe3+ among common cations with a low detection limit (0.11 μM, 0.006 ppm). More importantly, Tb3+@UiO-66–SO3H can realize highly sensitive and selective detection of tt-MA (detection limit, 0.58 μM, 0.083 ppm). Besides, this rapid response probe is facilely prepared, non-toxic and reusable, showing the potential of Tb3+@UiO-66–SO3H in the practical monitoring of tt-MA and Fe3+.
研究领域:
材料科学
·
分析化学
·
环境健康
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DOI
PubMed
高影响因子
ChemCatChem
·
2024
·
IF 3.8
Siyang Yan,Ruilin Feng,Jiaxu Liu,Chenxi Bai,Yanlong Qi
Graphical The dehydration of 2,4-pentanediol to unsaturated alcohol was performed over ceria-based catalysts with high selectivity. A stereocatalytic effect of CeO 2 catalyst was observed for the production of trans -3-penten-2-ol, with negligible content of cis -3-penten-2-ol. The transformation of biobased alkanediols over heterogeneous catalysts is a major object. Here, a series of catalysts were prepared for 2,4-pentanediol dehydration to 3-penten-2-ol. Ceria-based catalysts had a unique property of showing high efficiency. More importantly, a stereocatalytic effect was observed for CeO 2 , yielding trans -3-penten-2-ol with a high selectivity. Raman, XPS, TPD, and TPR were carried out to clarify the catalyst structure, and the relationship between the catalyst structure and catalytic performance were studied. The amount of Lewis acid sites can hardly be correlated with the total concentrations of the oxygen vacancies. It was suggested that the geometry structure of the active sites played a crucial role in trans -3-penten-2-ol production. The oxygen vacancies originating from CeO 2 consisted of active sites with a geometrical structure, which were different from those created by Pr doping CeO 2 . In addition, the Pr doping enhanced the oxygen migration, which resulted in side reactions, consequently, giving a lower selectivity to trans -3-penten-2-ol.
研究领域:
催化化学
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材料科学
·
绿色化学
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产品关联
DOI
高影响因子
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
·
2025
·Vol. 26
·期 5
·2251
·
IF 4.9
Canhong Wang,Yulan Wu,Bao Gong,Xiangsheng Zhao,Hui Meng,Junyu Mou,Xiaoling Cheng,Yinfeng Tan,Jianhe Wei
Dalbergia odoriferais widely used to treat cardiovascular diseases. Our research group found thatDalbergia odoriferavolatile oil has a good anti-myocardial ischemic effect, and its main pharmacodynamic components are trans-nerolol and its oxides. However, the exact mechanisms underlying this effect have not yet been elucidated. This study aimed to explore the potential myocardial protective effects of trans-nerolol and its underlying molecular mechanisms. Molecular docking was used to predict and visualize the possible mechanism of the anti-apoptotic myocardial protection by trans-nerolol. The myocardial protective effect of trans-nerolol was evaluated by observing pathological injury, myocardial enzyme levels, oxidation, antioxidant levels, and the expression of related proteins. Molecular docking results showed that trans-nerolol binds closely to cytochrome C (Cytc) and apoptosis-related proteins, suggesting that it may play a role in interacting with these target proteins. The results showed that pre-treatment with dose-dependent trans-nerolol significantly mitigated the myocardial histological damage; decreased lactate dehydrogenase (LDH), creatinine kinase (CK), alanine transaminase (ALT), and aspartate transaminase (AST) levels; reduced nitric oxide (NO) production, hydrogen peroxide (H2O2), and lipid peroxide (LPO); and increased the total antioxidant content (T-AOC), glutathione (GSH), catalase (CAT), and superoxide dismutase (SOD) activities compared with the model group. In addition, dose-dependent trans-nerolol significantly increased the Na+-K+-ATPase and Ca2+-Mg2+-ATPase levels. Moreover, trans-nerolol markedly reduced the endogenous and external apoptotic pathways; downregulated the protein expression of Cytc, apoptotic protease activating factor-1 (Apaf1), Fibroblast-associated (Fas), Cysteine-aspartate protease 3 (Caspase3), Cysteine-aspartate protease 8 (Caspase8), and Cysteine-aspartate protease 9 (Caspase9); and upregulated the expression of Heat shock protein 70 (Hsp70) and B-cell lymphoma-2 (Bcl-2). These data indicate that trans-nerolol exerts protective effects against myocardial ischemia (MI), and its mechanism is associated with the suppression of the Cytc- and caspase-signaling pathways. Trans-nerolol has a therapeutic effect on MI, and its mechanism of action is related to its anti-apoptotic effect. These results suggest thatDalbergia odoriferahas a potential role to be developed as an MI-promoting therapeutic agent.
研究领域:
药理学
·
心血管疾病
·
分子生物学
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产品关联
DOI
PubMed
高影响因子
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
·
2015
·
IF 2.912
Qian Lu,Qin Zhao,Qiong-Wei Yu,Yu-Qi Feng
In this study, a simple and convenient method for the determination of trans-resveratrol (TRA) in peanut oils based on pollen grain solid-phase extraction (SPE) was developed. Pollen grains were used as normal-phase SPE sorbent to separate TRA from peanut oils for the first time. As a naturally occurring material, pollen grains exhibited an excellent adsorption capacity for polyphenolic compounds due to their particular functional structures such as hydroxyl groups, saturated and unsaturated aliphatic chains with aromatics. Their stable compositions as well as adequate particle size (30–40 μm) also make them suitable for SPE. Several parameters influencing extraction performance were investigated. Coupled with high-performance liquid chromatography-ultraviolet detection (HPLC-UV), a green purification method for fast determination of TRA in peanut oils using pollen grain cartridges as sorbents was established. The linearity range of the proposed method was 10–2500 ng·g–1 with a satisfactory correlation coefficient (r2) of 0.9999. The limit of detection (LOD) for TRA in peanut oils was 2.7 ng·g–1, and the recoveries in spiked oil samples were from 70.2% to 98.4% with the relative standard deviations (RSDs) less than 4.9% (intraday) and 5.2% (interday). This method was successfully applied to the analysis of TRA in several peanut oils with different brands from local market as well as other kinds of vegetable oils.
研究领域:
食品科学
·
分析化学
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DOI
高影响因子
JOURNAL OF MATERIALS SCIENCE-MATERIALS IN ELECTRONICS
·
2024
·Vol. 35
·期 9
·1-11
·
IF 2.8
Yang Ting,Deng Haoyun,Zhang Zhengli,Hu Mi,Cheng Kaiqiang,Chen Yuanjian,Li Junli
Within organic solar cells (OSCs), the cathode interface layer (CIL) is indispensable for promoting the transport and extraction of charges. In this research, an environmentally friendly and cost-effective trans-cinnamic acid (TCA) is doped into PFN-Br to serve as the CIL in OSCs. The molecular structure and electronic structure of TCA were studied in this article using density functional theory (DFT) calculations executed with the Gaussian’16W software. The calculation results based on DFT indicate that TCA exhibits excellent planarity and the lowest unoccupied molecular orbital (LUMO) matching with PFN-Br. Excellent planarity and matched energy levels are advantageous for charge transport and harvesting. Doping TCA into the PFN-Br cathode interface layer improved charge extraction efficiency, and reduced charge recombination phenomena. Consequently, this led to a notable amplification in the maximum power conversion efficiency (PCE) of PBDB-T: IT-M -based non-fullerene devices, achieving an impressive 11.32%. This study furnishes an uncomplicated and cost-effective strategy for improving the PCE in OSCs.
研究领域:
材料科学
·
物理化学
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产品关联
DOI
高影响因子
WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY
·
2024
·Vol. 41
·期 1
·1-14
·
IF 4
Tan Xiaoli,Jiang Xiaobing,Chen Xiumei,Reymick Okwong Oketch,Zhu Chen,Tao Nengguo
Neofusicoccum parvum is one of the most hazardous pathogens causing mango fruit decay. The present study utilized trans -2-hexenal (TH), a typical antifungal component of plant essential oils (EOs), to control N. parvum both in vivo and in vitro, and attempted to explore the mechanisms involved. The findings showed that at concentrations greater than 0.4 µL/mL, TH exhibited exceptional antifungal activity against N. parvum in vitro. TH application led to the disruption of the structural integrity of both cell walls and cell membranes, with a particular impact on the latter, as evidenced by the dramatically increased propidium iodide level, as well as reduced total lipids and ergosterol content. Further DCFH-DA staining experiments showed that TH induced mycelial reactive oxygen species (ROS) accumulation, which exacerbated cell membrane lipid peroxidation. For easier application of TH, we fabricated aerogel-loaded TH (ALTH) materials, which demonstrated excellent antifungal activity in vitro. Infestation studies on fruits demonstrated that ALTH mitigated mango stem-end rot in a dose-dependent fashion, with a concentration of 40 µL/L showing efficacy comparable to the conventional fungicide prochloraz, while maintaining fruit quality. In light of these results, TH works by inducing ROS buildup and oxidative damage to the cell membrane of N. parvum , and is a particularly promising preservative for preventing postharvest infections in mangoes.
研究领域:
植物病理学
·
食品科学
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DOI
PubMed
高影响因子
APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY
·
2025
·
IF 3.3
Zhao Bingshan,Micklefield Jason,Wang Yonghua,Wang Fanghua
N-trans -feruloyltyramine (FLA) is one kind of phenylpropanoid compound found in various plants. Numerous studies have confirmed that it exhibits a wide range of physiological functions, such as antioxidant, ɑ-glucosidase inhibition, and anti-inflammatory activity. However, the low content of FLA in plants greatly limits its potential use in food and pharmaceutical industries. It is, therefore, very important to establish an effective synthesis of FLA. In this study, a green and efficient method to synthesize FLA was sought using an amide bond synthetase (ABS) biocatalyst. Ten kinds of ABS enzymes, including AlCfaL from Azospirillum lipoferum , were screened as the potential biocatalysts for the production of FLA. To obtain optimum reaction conditions, the effects of various parameters on conversion of FLA were firstly evaluated. Under the optimum conditions using 1 mM N-trans -ferulic acid, 50 mM tyramine (substrate ratio of 1:50), 10 mM MgCl₂, 8 mM ATP, and 35 µM AlCfaL enzyme at 30 °C with a shaking speed of 500 r/min for 48 h, maximum conversion rate of 74% was reached. Given that the amidation reaction is mediated by relative expensive ATP, we further optimized reaction systems to incorporate an ATP recycling system consisting of a polyphosphate kinase enzyme (CHU) and an inexpensive polyphosphate (PolyP) as the phosphate donor. Response surface methodology (RSM) based on five-level, five-variable central composite design (CCD) was used to evaluate the optimal parameters for the production of FLA. The effects of AMP, PolyP, AlCfaL, CHU concentrations, and reaction time on the conversion rate of FLA were analyzed. The optimum conditions derived via RSM were 7.12 mM AMP, 5.96 mg/mL PolyP, 39.72 μM AlCfaL, 27.68 μM CHU, and a reaction time of 36 h. Validation experiments conducted under these optimized conditions yielded an actual conversion rate of 63.5%, which compared well to the maximum predicted value of 64.2%.
研究领域:
生物化学
·
酶工程
·
食品科学
·
药学
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DOI
PubMed
高影响因子
JOURNAL OF ECONOMIC ENTOMOLOGY
·
2021
·Vol. 114
·期 2
·979-987
·
IF 2.381
Cui Kaidi,He Leiming,Cui Guangrui,Zhang Tao,Chen Yue,Zhang Tao,Mu Wei,Liu Feng
Grain commodities in postharvest storage often deteriorate because of fungal and insect attacks. With the green consumption requirements of consumers, ecofriendly and safe pesticides are needed for grain storage. The current study investigated the efficacy of the plant volatile compound trans-2-hexenal against the storage insect pest Tribolium castaneum (Herbst) and three commonly occurring storage fungi, viz., Fusarium graminearum, Aspergillus flavus, and Aspergillus niger, to recommend its application as a botanical fumigant for grain commodities. trans-2-Hexenal weakly repels T. castaneum but has favorable insecticidal activity against multiple developmental stages of T. castaneum, ranging in sensitivity as follows: eggs (LC50 = 14.3 µl/l) > adults (31.6 µl/l) > young larvae (42.1 µl/l) > mature larvae (64.5 µl/l) > pupae (70.5 µl/l). Moreover, trans-2-hexenal caused a high malformation rate and high mortality in adults developed from fumigated pupae. In a 7-d grain, trans-2-hexenal at 0.8 µl/ml provided an appreciable efficacy (81.3%), and concentrations ≥ 0.1 µl/ml completely inhibited the offspring of T. castaneum. trans-2-Hexenal was nonphytotoxic to the seed germination and seedling growth of wheat seeds. Furthermore, trans-2-hexenal completely inhibited the growth of A. flavus, F. graminearum, and A. niger at 5, 10, and 10 µl/l, respectively. The favorable biological activity of trans-2-hexenal against T. castaneum and three frequently occurring mycotoxigenic storage fungi indicated the potential of trans-2-hexenal for simultaneously controlling pests and pathogens, which could reduce its application frequency in grains and decrease pesticide resistance risks.
研究领域:
昆虫学
·
植物化学
·
食品科学
·
真菌学
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DOI
高影响因子
JOURNAL OF CHROMATOGRAPHY A
·
2013
·
IF 4.612
Chao Han,Jinfang Xu,Xiaobing Wang,Xiaoming Xu,Jianguang Luo,Lingyi Kong
A preparative chiral high speed counter-current chromatography (HSCCC) method based on induced circular dichroism (ICD) spectrum was developed to separate trans -δ-viniferin (TVN) enantiomers successfully. The important parameters for the chiral HSCCC separation process, including the type of chiral selector (CS), the concentration of chiral selector and the equilibrium temperature, were optimized using induced circular dichroism spectrum. The final separation procedure was established with a biphasic solvent system composed of n -hexane–ethyl acetate–25 mmol L −1 hydroxypropyl-β-cyclodextrin aqueous solution (5:5:10, v/v/v) in the head-to-tail elution mode at 5 °C. Under optimum chiral HSCCC separation conditions, 8.2 mg of (7 S , 8 S )-TVN ( 1 ) and 9.4 mg of (7 R , 8 R )-TVN ( 2 ) were successfully separated from 20 mg TVN enantiomers with the purity of 99.51% and 99.36%, respectively.
研究领域:
分析化学
·
植物化学
✓ 已验证
DOI
PubMed
高影响因子
JOURNAL OF APPLIED POLYMER SCIENCE
·
2024
·Vol. 142
·期 10
·e56550
·
IF 2.7
Yuhang Huang,Yingkang Zhu,Lijun Cao,Yidan Jing,Zhigang Xu,Guochu Tang,You Shu,Xiaoqing Liu,Xiaomin Zhang
The photo-induced cis-trans isomerization of azobenzene molecules, known for their significant color changes, is extensively utilized in the functional modification of polymeric materials. However, the research on the functionalization of biomass-based polyesters with azobenzene is limited. A key raw material for biomass-based coatings possess reactive double bonds and excellent film-forming capabilities, offering significant advantages for azobenzene functionalization in biomass-based polyester applications. In this study, AESO served as the polyester matrix and acrylate azobenzene derivatives as the functional molecules. Under ultraviolet radiation, AESO underwent a carbon–carbon crosslinking reaction with the azobenzene derivatives to synthesize a novel resin. The coating of this resin on a PET substrate exhibited excellent pencil hardness (3B), adhesion (5B), and solvent resistance. By alternating exposure to ultraviolet and blue light, the coating displayed reversible switching between cis and trans isomers, enabling reversible writing and erasing of patterns. Even after 20 cycles of writing and erasing, high-resolution patterns could still be observed (clearly visible under a 12x microscope). Furthermore, the image could be retained for up to 2 h under sunlight irradiation. This study presents a new method for functionalizing biobased polyesters.
研究领域:
材料科学
·
生物质化学
·
光学材料
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DOI
高影响因子
FOOD CHEMISTRY
·
2022
·
IF 9.231
Tian Li,Qin Guo,Yang Qu,Hongzhi Liu,Li Liu,Yu Zhang,Qiang Wang
The unanticipated inhibitory effect of trans -resveratrol ( trans -Res) on the formation of trans fatty acids (TFAs) by thermal isomerization of peanut oil (PO) and its mechanism were investigated by experiment and density functional theory. Results showed that trans -Res inhibited the amount and formation rate of TFAs. t rans -Res first inhibited the formation of C18:2, then C18:1, by the mechanism of proton transfer isomerism. The most active reaction site of trans -Res (4′-OH free radical) preferentially combined with the OOL-L-C11• (di-allyl) and then with OOL-O-C11• (mono-allyl) allyl groups in PO, resulting in the higher reaction energy barrier of speed control steps in OOL-L (transition state 1) and OOL-O (transition state 2), and the lower reaction rate of OOL-L and OOL-O (both decreased by 1–10 3 times), to reduce the formation of TFAs. Our study provided a theoretical foundation for the precise regulation of natural hydroxy compound to TFAs in oil.
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产品关联
DOI
PubMed
高影响因子
INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY
·
2013
·Vol. 48
·期 11
·2324-2330
·
IF 1.24
Ming Cai,Xiangyang Guo,Hanhua Liang,Peilong Sun
Summary In this study, microwave-assisted extraction with ethanol (MAEE) of star anise oil from Illicium verum Hook.f . has been optimised by response surface methodology (RSM). A maximum yield of star anise oil was obtained at an optimum condition: the ratio of solvent to sample 17 mL g −1 , extraction time 16 min and microwave power 505 W. Accordingly, the highest yield of star anise oil was about 24.98%, which was much higher than that of steam distillation (SD), 7.17%. Oxygenated organic compounds in representative of trans-anethole are a major component in star anise oil, nearly 94.21% for SD and 86.66% for MAEE, identified and determined by GC-MS. The oils extracted by SD and MAEE both have strong antioxidant activities that were demonstrated by the DPPH and ABTS assays.
研究领域:
植物化学
·
食品科学
·
分析化学
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）