MATERIALS CHEMISTRY AND PHYSICS
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2023
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IF 4.6
Lin Yang,Tingjiao Liu,Zheng Li,Changqing Liu,Feifeng Wang,Chunshan Wu
The application of metal organic frameworks (MOFs) for the recovery of low concentrations of rare-earth elements (REEs) has attracted increasing attention due to the precious value of REEs resources. In this study, UiO-66-COOH was modified by trifluoroacetic acid (TFA) to not only promote material crystallization and the pore structure verified by XRD and SEM characterization, but successfully enhance its adsorption capacity and achieve perfect selectivity for Lanthanum ion (La 3+ ). The adsorption capacity for UiO-66-COOH-24TFA was increased by 58% compared to unmodified material. The adsorption mechanism and application were comprehensively investigated. By adsorption kinetics , isotherm and thermodynamic studies, it was found that the adsorption process mainly exhibited monolayer adsorption with spontaneous endothermic-chemisorption characteristics, and –COOH of the modified materials (UiO-66-COOH-24TFA) played an important role, which was confirmed by XPS. Moreover, UiO-66-COOH-24TFA was applied to REEs actual wastewater by successive six-stage adsorption process , where the overall recovery rate on La 3+ reached 94.1% under the coexisting conditions of multiple ions. The application of this acid modified material in the field of the separation and recovery of REEs is of great promise.
研究领域:
材料科学
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环境科学
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高影响因子
FLUID PHASE EQUILIBRIA
·
2015
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IF 2.2
Zhixian Huang,Ling Li,Miaomiao Zhou,Haiming Jiang,Ting Qiu
Vapor–liquid equilibrium data for ethyl trifluoroacetate + trifluoroacetic acid , ethyl trifluoroacetate + ethanol, and trifluoroacetic acid + water at the pressure 101.3 kPa were measured with a modified Rose still. The thermodynamic consistency of the VLE data was confirmed by Herrington’s method. The VLE data were correlated by the NRTL and Wilson models with satisfactory results, and the interaction parameters of these mixtures were estimated.
研究领域:
化学工程
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热力学
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高影响因子
ACS Applied Polymer Materials
·
2025
·
IF 4.7
Wenjun Lu,Baiwang Sun
Trifluoroacetic acid (TFA) is a ubiquitous and persistent environmental pollutant with significant environmental and human health impacts. To the best of our knowledge, no study has reported the use of porous organic polymers to adsorb TFA vapor. In this study, we successfully synthesized a polymer (POPSP-4) that exhibits both physical and chemical adsorption for efficient TFA capture, and physical adsorption can occur at the sulfur sites. With the assistance of organic bases, the adsorption capacity of the polymer increases from 2.3 g·g–1 to over 4 g·g–1 in 1 h and effectively prevents the escape of TFA from the polymer. This study presents a promising methodology for the design and synthesis of porous organic materials, specifically for the efficient capture of TFA vapor.
研究领域:
材料科学
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环境科学
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高影响因子
ENVIRONMENTAL SCIENCE & TECHNOLOGY
·
2026
·
IF 12.2
Xiaolian Cao,Shuting Huang,Chenxin Li,Shuxin Jiang,Junru Li,Yingying Zhou,Kaiqin Huang,Wei Ma,Yu Chu,Panna Yang,Xiaoxing Kou,Yitao Pan,Shengtao Ma,Jiayin Dai,Xifei Yang,Yanhong Wei
Abstract Trifluoroacetic acid (TFA) is a two-carbon ultrashort-chain per- and polyfluoroalkyl substance (PFAS) and constitutes the most abundant PFAS in the environment. TFA has historically been regarded as a compound of relatively low acute lethality, yet its adverse effects on sensitive targets at environmentally relevant levels are largely unknown. Due to extreme hydrophilicity and anionic form in the aqueous phase of blood, TFA manifests high accessibility to the innermost layer of vasculature. In this study, we investigated the vascular toxicity of TFA using human umbilical vein endothelial cell and zebrafish embryo models at concentrations of 0.8–2000 μg/L. The results showed that TFA exposure reduced ATP content, lactate production, and glycolytic flux, concomitantly increasing pyruvate accumulation. The benchmark dose lower confidence limit (BMDL5) values ranged from 0.44 to 2.65 μg/L, falling within the range of environmental levels. Enzyme kinetics and molecular docking indicated that TFA competitively inhibited lactate dehydrogenase (LDH) at the pyruvate-binding site. In addition, TFA inhibited endothelial migration, induced cellular F-actin disruption, and impaired vascular development in zebrafish larvae. The AI-aided vascular phenomics revealed the most prominent defect in the subintestinal venous plexus. A quantitative adverse outcome pathway was subsequently established, and key-event relationships were robustly fitted, with R2 values exceeding 0.72. This study unravels a metabolic perturbation pathway of TFA-induced vascular toxicity and reinforces the need to reassess the health risks of TFA.
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高影响因子
Journal of Water Process Engineering
·
2026
·
IF 6.6
Shiyu Ge,Yanbang Ku,Wenyu Wang,Jing Xu,Feng Wu
Rapid defluorination of TFA in water is achieved using the anoxic UVC/S(IV) system. • UVC-induced S(IV) photoactivation generates hydrated electrons for C–F bond cleavage. • Key operational parameters for the defluorination process are optimized. • Kinetic simulation verifies stepwise hydrated-electron-mediated defluorination pathway. Trifluoroacetic acid (TFA), a representative ultrashort-chain PFAS, is highly mobile, persistent, and difficult to remove by conventional water treatment. In this study, an anoxic UVC/S(IV) system was developed for rapid TFA defluorination through sulfite photoactivation and hydrated-electron-induced C–F bond cleavage. The individual roles of UVC irradiation, sulfite, and dissolved oxygen (DO) were first examined, followed by evaluation of operating factors and water-matrix components. Negligible defluorination occurred with UVC or sulfite alone, whereas their combination induced rapid fluoride release, confirming the essential role of sulfite photoactivation. DO strongly inhibited defluorination by scavenging hydrated electrons, indicating that oxygen exclusion is necessary. Under baseline conditions of pH 11, 20 mM sulfite, and 0.2 mM TFA, approximately 90% defluorination was achieved within 30 min. Temperature, pH, sulfite concentration, and photon flux were the main factors governing fluoride release. Ca 2+ , Mg 2+ , NO 3 − , and humic acid markedly inhibited TFA defluorination, while Na + , K + , Cl − , and SO 4 2− showed little effect. A kinetic model incorporating sulfite photoactivation, hydrated-electron reactions, stepwise defluorination, and S(IV) depletion reproduced the experimental trends. Overall, this work clarifies the operating conditions and matrix limitations of an anoxic UVC/S(IV) process for TFA defluorination. Download: Download high-res image (261KB) Download: Download full-size image
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Nature Communications
·
2017
·Vol. 8
·期 1
·1-7
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IF 12.124
Lin Jin,Li Zhi,Kan Jian,Huang Shijun,Su Weiping,Li Yadong
Catalytic oxidative C–H bond functionalization reactions that proceed without requiring stoichiometric amounts of external oxidants or pre-functionalized oxidizing reagents could maximize the atom- and step-economy in chemical syntheses. However, such a transformation remains elusive. Here, we report that a photo-driven catalytic process enables decarboxylative C–H trifluoromethylation of (hetero)arenes with trifluoroacetic acid as a trifluoromethyl source in good yields in the presence of an external oxidant in far lower than stoichiometric amounts (for example, 0.2 equivalents of Na 2 S 2 O 8 ) using Rh-modified TiO 2 nanoparticles as a photocatalyst, in which H 2 release is an important driving force for the reaction. Our findings not only provide an approach to accessing valuable decarboxylative C–H trifluoromethylations via activation of abundant but inert trifluoroacetic acid towards oxidative decarboxylation and trifluoromethyl radical formation, but also demonstrate that a photo-driven catalytic process is a promising way to achieve external oxidant-free C–H functionalization reactions.
研究领域:
有机化学
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催化
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光化学
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DOI
PubMed
高影响因子
Journal of CO2 Utilization
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2018
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IF 5.503
Keng Xuan,Yanfeng Pu,Feng Li,Aixue Li,Jing Luo,Lei Li,Feng Wang,Ning Zhao,Fukui Xiao
A series of trifluoroacetic acid (TFA) modulated metal-organic frameworks UiO-66 catalysts were synthesized for the direct synthesis of dimethyl carbonate (DMC) from CO 2 and methanol in this work. Characterization results show that the surface area, pore size, pore volume as well as the amount of missing-linker defects, Lewis acid site, Lewis basic site and hydroxyl of UiO-66-X can be tuned by regulating the amount of TFA modulator. Catalytic activity assessments reveal that TFA modulation enhanced the activity of UiO-66-X. The catalytic activity improvement of the UiO-66-X could be attributed to the increased amount of active sites and the enlargement of porosity originated from TFA modulation. Moreover, a possible reaction mechanism for DMC synthesis from CO 2 and methanol over UiO-66-X was proposed based on the in situ FT-IR results.
研究领域:
化学工程
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材料科学
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DOI
高影响因子
ANALYTICAL CHEMISTRY
·
2019
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IF 6.35
Xiaoqun Wang,Yiwen Hou,Zhuanghao Hou,Wei Xiong,Guangming Huang
Imaging of cholesterol and other metabolites simultaneously by ambient mass spectrometry will greatly benefit biological studies, however, it still remains challenging. Herein, by adding acid into the desorption electrospray ionization (DESI) spray solvent, we achieved simultaneous mass spectrometry imaging of cholesterol and other metabolites directly from mouse brain sections. The introduction of acid increased the signal intensity of cholesterol in mouse brain tissues by approximately 21-fold. Additionally, the present strategy provided increased signal intensities for other metabolites up to 62-fold, as well as identification of seven more metabolites (23 vs 16 for acid-enhanced DESI vs DESI). Moreover, increased corelationships for alanine as well as putrescine and spermidine with cholesterol were discovered under acid-enhanced DESI. The potential of the present strategy in the fields of biological and medical research was demonstrated by investigating the level change for cholesterol, alanine, putrescine, and spermidine in Alzheimer’s disease (AD) mouse brain.
研究领域:
生物学
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医学研究
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DOI
PubMed
高影响因子
Journal of Materials Chemistry A
·
2024
·Vol. 12
·期 23
·13830-13840
·
IF 10.7
Xia Hu,Yao Wang,Weiqian Guo,Yao Tian,Xiang Zhang,Feiyu Kang,Dong Zhou,Baohua Li
Garnet electrolyte-based solid-state lithium metal batteries (SLMBs) are attractive owing to their high energy density and high safety. However, garnet electrolytes are sensitive to humid air, forming Li2CO3-rich contaminants on the surface that trigger a high kinetic barrier and premature battery failure. Herein, a straightforward “waste-to-treasure” strategy is proposed to transform Li2CO3 on a Li6.4La3Zr1.4Ta0.6O12 (LLZTO) surface into LiF by solvent-free trifluoroacetic acid (TFA)-induced interfacial engineering. The as-formed LiF interfacial layer with electronically insulating nature effectively improves the interface wettability between the Li anode and LLZTO, reduces the interface resistance and produces a symmetric cell with an ultralong-lifespan of up to 10 000 h at 0.1 mA cm−2. Furthermore, the SLMB paired with the LiFePO4 cathode delivers a high capacity of 155.6 mA h g−1 at 0.5C and retains 78% of the initial capacity after 900 cycles. This study offers a facile strategy to overcome the limitations associated with surface impurities, addresses critical interface issues, and accelerates the practical application of garnet-type solid-state electrolytes in high-performance SLMBs.
研究领域:
材料科学
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电化学
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DOI
高影响因子
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2024
·
IF 7.7
Yuanqi Duan,Zhengyu Hu,Long Jin,Tieqiang Zong,Xiaohui Zhang,Yanan Liu,Pengcheng Yang,Jinfeng Sun,Wei Zhou,Gao Li
The degradation of Belamcanda chinensis (L.) DC. polysaccharides was carried out by five concentrations of trifluoroacetic acid (TFA) (1–5 mol/L), and their physicochemical properties, degradation kinetics and anticomplementary activity were investigated. The findings revealed a notable reduction in the molecular weight of BCP, from an initial value of 2.622 × 10 5 g/mol to a final value of 6.255 × 10 4 g/mol, and the water solubility index increased from 90.66 ± 0.42 % to 97.78 ± 0.43 %. The degraded polysaccharides of B. chinensis exhibited a comparable monosaccharide composition comprising Man, GalA, Glc, Gal, and Ara. As the concentration of TFA increased, the degradation rate constant increased from 1.468 × 10 −3 to 5.943 × 10 −3 , and the process followed the first-order degradation kinetic model (R 2 > 0.97) and the random fracture model (R 2 > 0.96). Furthermore, the five degraded polysaccharides still exhibit good thermal stability. In vitro experiments showed that DBCP-3 exhibited more potent anticomplementary activity than the original polysaccharides and positive drugs, which was strongly correlated with its Mw ( r = 0.6–0.8), inhibiting complement activation by blocking C2 and C4. These results indicated that TFA degradation has a positive effect on polysaccharides, of which DBCP-3 is expected to treat diseases involving hyperactivation of the complement system.
研究领域:
植物化学
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免疫学
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药理学
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DOI
PubMed
高影响因子
MICROCHEMICAL JOURNAL
·
2024
·
IF 4.9
Leikeqing Shen,Xueping Dang,Huaixia Chen
The development of adsorption materials with good stability and high efficiency is significant in solid-phase microextraction (SPME). In this work, metal–organic framework MOF-808 (Zr) was modified by trifluoroacetic acid (TFA) to improve its hydrophobicity. MOF-808-TFA was electrochemically deposited on stainless steel wire with poly (3, 4-ethylenedioxthiophene) (PEDOT) to increase its extraction efficiency. The main parameters in the synthesis and extraction procedure were optimized. The prepared MOF-808-TFA@PEDOT nanocomposite coating was characterized by scanning electron microscopy, energy dispersive spectrometer, X-ray diffraction, Fourier transform infrared spectrometry and thermogravimetric analysis. A direct immersion solid-phase microextraction (DI-SPME) method for six phenols was developed based on the nanocomposite coating which had good service life (150 times). The extraction efficiency was 12 times higher than the commercial PDMS coating. Combined with gas chromatography-flame ionization detector (GC-FID), a simultaneous determination method for the six phenols was established, which exhibited wide linear range with 0.05–50 μg L −1 ( R 2 > 0.99). The limit of detection was 0.01–0.08 μg L −1 (S/N = 3), and the limit of quantification was 0.05–0.25 μg L −1 . The method was applied to determine the migration quantity of phenols from four metal cans with recovery rate between 85.6–116.8 % (RSD < 13.9 %), and it was verified by standard GC–MS method and SPSS statistical analysis. These results indicated the DI-SPME-GC-FID method had reliability and potential application in security testing for food contact materials.
研究领域:
分析化学
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材料科学
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环境科学
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DOI
高影响因子
ACS Applied Energy Materials
·
2020
·
IF 4.473
Zhiyong Zhao,Zhihua Liu,Qishi Zhong,Yujun Qin,Aizhen Xu,Wen Li,Jiahua Shi
Trifluoroacetic acid (TFA) is used for the first time as dopant in the synthesis of the graphene oxide/polyaniline (GO/PANI) composite. The composite was prepared through fast in situ polymerization of aniline (ANI) on GO sheets. After filtration and freeze-drying, the GO/PANI was reacted with hydrazine hydrate to produce reduced graphene/polyaniline (rGO/PANI). In the rGO/PANI, the morphology of PANI can be easily controlled by adjusting the mass ratio of GO to ANI. Oriented PANI was evenly and tightly attached on the rGO backbone to form a hierarchical composite for use as an electrode material in a flexible all-solid-state supercapacitor (ASSSC) with symmetric structure. At the optimal ratio of GO to ANI, the rGO/PANI on carbon cloth attained a high specific capacitance of 810 F g–1 at a current density of 1 A g–1 in a three-electrode system. The energy storage mechanism of the rGO/PANI was found to be mainly controlled by the surface redox reaction process. The rGO/PANI-based symmetric ASSSC displayed considerable capacitance retention of 91.3% after 2000 cycles. Furthermore, the device exhibited a maximum energy density of 62.2 Wh kg–1 at a power density of 0.8 kW kg–1. These favorable properties are primarily attributed to the enhanced interaction between rGO and PANI after the introducing of TFA, which accelerates the electron/ion transfer during charging and discharging by the synergistic effects of double-layer capacitance and pseudocapacitance.
研究领域:
材料科学
·
能源存储
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高影响因子
危险品化学品经营许可证（带存储）