Wheat germ lectin (WGA) from Triticum vulgaris exists as a homodimer and has multiple N-acetyl glucosamine (GlcNAc) binding sites. It is resistant to protein denaturation agents and is used for the detection of O-GlcNAc proteins. WGA binding to N-glycolylneuraminic acid (Neu5Ac) may modulate pro-inflammatory immune response.
Application:
Lectin from Triticum vulgaris (wheat) has been used:
in lectin binding assay of samples from intrauterine stages of filarial parasites
in the histological studies of mice myocytes
for the generation bead-biotin-WGA complex with Dynabeads M-280 Streptavidin magnetic beads for lectin magnetic separation of Toxoplasma gondii oocytes from water samples