Anti-inflammatory agent 74 (B5) is an anti-inflammatory agent that can inhibit NO , IL-6 , and TNF-α , with IC 50 values of 10.88 μM and 4.93 μM for NO and IL-6 , respectively. Anti-inflammatory agent 74 alleviates acute lung injury (ALI) by regulating inflammatory mediators and inhibiting the MAPK and NF-κB signaling pathways.