5′-Azido-2′,5′-dideoxy-2′-fluorouridine

CAS: 1012080-88-4 货号: A1426899 PubChem CID: 168006055
有货
储存条件
-20°C储存
运输条件
超低温运输
★
规格
库存
价格
数量
1mg
A1426899-1mg
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概述


5′-Azido-2′,5′-dideoxy-2′-fluorouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis , etc. 5′-Azido-2′,5′-dideoxy-2′-fluorouridine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

规格

英文名称
5′-Azido-2′,5′-dideoxy-2′-fluorouridine
储存条件
-20°C储存
运输条件
超低温运输
名称和识别符
分子类型
小分子
IUPAC Name
1-[5-(azidomethyl)-3-fluoro-4-hydroxyoxolan-2-yl]pyrimidine-2,4-dione
INCHI
1S/C9H10FN5O4/c10-6-7(17)4(3-12-14-11)19-8(6)15-2-1-5(16)13-9(15)18/h1-2,4,6-8,17H,3H2,(H,13,16,18)
InChi Key
IKZBULOUWHBODB-UHFFFAOYSA-N
Smiles
C1=CN(C(=O)NC1=O)C2C(C(C(O2)CN=[N+]=[N-])O)F
PubChem CID

高级数据

三维结构
交互式化学结构模型





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