计算溶液所需的质量、体积或浓度。
,适用于对基线干扰要求严格的色谱和分析工作流程。
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在色谱分析、有机合成和交叉偶联反应领域已被 0 篇同行评审文献引用。
AKR1C3-IN-9 is a selective inhibitor of Aldo-keto Reductase 1C3 (AKR1C3) with an IC 50 value of 8.92 nM. AKR1C3-IN-9 significantly reverses the Doxorubicin ( HY-15142A ) (DOX) resistance in a resistant breast cancer cell line.
IC50& Target:IC50: 8.92 nM (AKR1C3)
In Vitro:AKR1C3-IN-9 (compound 24) (10-100 μM; 72 h and 96 h) results weak antiproliferative effect up to 100 μM in all three breast cancer cell lines (MDA-MB-231, MCF-7). AKR1C3-IN-9 (10 μM, 25 μM, and 50 μM; 72 h) synergistically inhibits the proliferation
Biological Activity:AKR1C3-IN-9 is a selective inhibitor of Aldo-keto Reductase 1C3 (AKR1C3) with an IC 50 value of 8.92 nM. AKR1C3-IN-9 significantly reverses the Doxorubicin ( HY-15142A ) (DOX) resistance in a resistant breast cancer cell line.