Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negative regulator of osteogenesis.
宿主种属
兔(Rabbit)
特异性
14-3-3 alpha/beta/zeta/delta
种属反应性
人(Human),大鼠(Rat),小鼠(Mouse)
免疫原
A synthetic peptide derived from human 14-3-3 alpha/beta (AA 1-50).
阳性对照
WB: HeLa, Jurkat, Hep G2, MCF7, A549, NIH/3T3 and C6 cell lysates. IHC: Human breast cancer tissue.
Recombinant 14-3-3 alpha/beta/zeta/delta Antibody (Ab086582) - Western Blot All lanes: Recombinant 14-3-3 alpha/beta/zeta/delta Antibody (Ab086582) at 1/1000 dilution Samples: Lysates at 20 µg per lane Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution
Predicted band size: 28 kDa Observed band size: 28, 29 kDa Exposure time: 9.4 s
Recombinant 14-3-3 alpha/beta/zeta/delta Antibody (Ab086582) - IHC Immunohistochemical analysis of paraffin-embedded human breast cancer, using Recombinant 14-3-3 alpha/beta/zeta/delta Antibody (Ab086582).